iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000022043.18	ENSMUST00000022623.12	ENSMUSP00000022623.6
ENSMUSG00000022043.18	ENSMUST00000121006.1	ENSMUSP00000112877.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	microRNA	TRANSFAC	RepTar
RAID2
Protein-protein Interaction
HINT
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.30e-07	32.6	31	99
E3 activity/RING/RING	1.40e-06	29.9	36	76

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwlasggk.tcPvtrqplteedlvPnltlrrliqawce 70
            ee+lC++ ++++rd v+l +G+ + r+++  + + + + +cPv++++  + +l  n+tl +l++  + 
   Q: 31   KEELLCAVCYDPFRDAVTLRCGHNFCRRCVSGCWEVQTTpSCPVCKERAVPGELRTNHTLNNLVETLLR 99
           689******************************9888888**********************9987665 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           Ca+C+++f+d  ++l+CgH f++ C+  +w     + +++ +CP+C+
   Q: 36   CAVCYDPFRD-AVTLRCGHNFCRRCVsGCW-----EVQTTPSCPVCK 76
           ********99.999************9999.....79999******7 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MKAATPVVVT AAAPAMEPGP SVSPGPSRSF KEELLCAVCY DPFRDAVTLR CGHNFCRRCV 60
SGCWEVQTTP SCPVCKERAV PGELRTNHTL NNLVETLLRE EAEGARWTGR RSPRPCRAHR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCCCAGATCT TCAGCAGGGA CAACGCCCGC AGGCTAGGCA TGAAGGCGGC GACACCGGTG 60
GTGGTGACGG CGGCTGCTCC TGCGATGGAG CCGGGCCCTT CTGTGTCCCC GGGGCCTTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box
PF13445--zf-RING_UBOX

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005622--C:intracellular
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0045930--P:negative regulation of mitotic cell cycle
GO:1902187--P:negative regulation of viral release from host cell
GO:0043065--P:positive regulation of apoptotic process

KEGG

mmu:66854

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001788	Ailuropoda melanoleuca	80.00	0.00e+00	852.00
IUUC-Apl-003958	Anas platyrhynchos	49.49	8.00e-122	430.00
IUUC-Aca-005199	Anolis carolinensis	42.72	8.00e-116	410.00
IUUC-Bta-013359	Bos taurus	78.07	0.00e+00	810.00
IUUC-Cja-018900	Callithrix jacchus	69.04	0.00e+00	721.00
IUUC-Cfa-020685	Canis familiaris	80.20	0.00e+00	857.00
IUUC-Cpo-022253	Cavia porcellus	73.00	0.00e+00	727.00
IUUC-Csa-023777	Chlorocebus sabaeus	80.60	0.00e+00	852.00
IUUC-Dno-029065	Dasypus novemcinctus	75.29	0.00e+00	813.00
IUUC-Dor-030248	Dipodomys ordii	59.04	9.00e-95	339.00
IUUC-Ete-033183	Echinops telfairi	68.00	0.00e+00	677.00
IUUC-Eca-033263	Equus caballus	77.61	0.00e+00	728.00
IUUC-Eeu-034699	Erinaceus europaeus	73.58	1.00e-107	383.00
IUUC-Fca-036366	Felis catus	79.20	0.00e+00	843.00
IUUC-Fal-037257	Ficedula albicollis	52.57	5.00e-145	507.00
IUUC-Gmo-038512	Gadus morhua	35.17	1.00e-65	244.00
IUUC-Gga-041125	Gallus gallus	49.86	1.00e-98	352.00
IUUC-Ggo-045233	Gorilla gorilla	79.88	5.00e-157	546.00
IUUC-Hsa-046042	Homo sapiens	80.60	0.00e+00	853.00
IUUC-Itr-048751	Ictidomys tridecemlineatus	78.32	0.00e+00	816.00
IUUC-Laf-054322	Loxodonta africana	79.84	0.00e+00	827.00
IUUC-Mcc-055555	Macaca mulatta	78.66	0.00e+00	833.00
IUUC-Meu-055900	Macropus eugenii	71.07	0.00e+00	729.00
IUUC-Mga-059380	Meleagris gallopavo	52.23	2.00e-98	352.00
IUUC-Mmr-061296	Microcebus murinus	78.20	0.00e+00	822.00
IUUC-Mdo-062811	Monodelphis domestica	71.14	0.00e+00	738.00
IUUC-Mpu-066219	Mustela putorius furo	79.92	0.00e+00	829.00
IUUC-Mlu-067033	Myotis lucifugus	76.40	0.00e+00	814.00
IUUC-Nle-069806	Nomascus leucogenys	80.38	0.00e+00	795.00
IUUC-Opr-070248	Ochotona princeps	71.40	0.00e+00	708.00
IUUC-Ont-072047	Oreochromis niloticus	33.06	4.00e-66	245.00
IUUC-Oan-073364	Ornithorhynchus anatinus	61.34	4.00e-93	333.00
IUUC-Ocu-074572	Oryctolagus cuniculus	80.91	0.00e+00	872.00
IUUC-Oga-088378	Otolemur garnettii	78.80	0.00e+00	822.00
IUUC-Oar-089516	Ovis aries	77.62	0.00e+00	798.00
IUUC-Ptr-091313	Pan troglodytes	80.60	0.00e+00	853.00
IUUC-Pan-092877	Papio anubis	80.80	0.00e+00	853.00
IUUC-Psi-093928	Pelodiscus sinensis	54.90	1.00e-153	536.00
IUUC-Pfo-096690	Poecilia formosa	34.09	1.00e-68	253.00
IUUC-Pab-098624	Pongo abelii	80.20	0.00e+00	845.00
IUUC-Pca-100469	Procavia capensis	72.90	0.00e+00	753.00
IUUC-Pva-103227	Pteropus vampyrus	79.80	0.00e+00	849.00
IUUC-Rno-105778	Rattus norvegicus	98.97	0.00e+00	953.00
IUUC-Sha-107392	Sarcophilus harrisii	62.38	0.00e+00	637.00
IUUC-Sar-113297	Sorex araneus	72.09	4.00e-52	197.00
IUUC-Ssc-115739	Sus scrofa	78.69	0.00e+00	812.00
IUUC-Tru-117718	Takifugu rubripes	30.31	1.00e-60	227.00
IUUC-Tbe-127926	Tupaia belangeri	76.31	2.00e-123	436.00
IUUC-Ttr-129293	Tursiops truncatus	80.20	0.00e+00	843.00
IUUC-Vpa-130379	Vicugna pacos	78.76	3.00e-143	500.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence