iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-090842

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03118794

Gene Name

ZNRF4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000010331.2	ENSPTRT00000018987.2	ENSPTRP00000017574.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.60e-10	39.9	309	352

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdg..plvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiCl+++k+g  +++lpC H++h++C+  w     s+ ++ +CP+C+
   Q: 309  CAICLDEYKEGdqLKILPCSHTYHRKCIDPW----FSQAPRRSCPVCK 352
           ********66555******************....9***********7 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

VLLCRLEHLM PRASRVTVAA SLPLSHAVIP TQLPSRPGHR PPGRPRRCPK ASCLPPPVGP 60
SSTQPAKRVT MGWPRPGRAL VAVKALLVLS LLQVPAQAVV RAMLEDNSSS VDFADLPALF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCTGCCAGA AAGGCTACCT GCGCCAGCAC CTCCTGAGAC CGGCCTTCAA AGACACGATG 60
CGTGCTGCTC TGCCGTCTGG AGCACTTAAT GCCTAGAGCC AGCAGGGTTA CAGTGGCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003137--PA_domain
IPR001841--Znf_RING
IPR011016--Znf_RING-CH
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF02225--PA
PF13639--zf-RING_2

SMART

SM00184--RING
SM00744--RINGv

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0016021--C:integral component of membrane
GO:0008270--F:zinc ion binding
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001654	Ailuropoda melanoleuca	70.46	1.00e-132	466.00
IUUC-Bta-012572	Bos taurus	66.32	1.00e-113	403.00
IUUC-Cja-019445	Callithrix jacchus	77.99	5.00e-149	520.00
IUUC-Cfa-020828	Canis familiaris	71.30	6.00e-121	427.00
IUUC-Csa-023281	Chlorocebus sabaeus	89.98	1.00e-174	605.00
IUUC-Dor-030690	Dipodomys ordii	53.52	1.00e-57	216.00
IUUC-Ete-032610	Echinops telfairi	65.00	1.00e-119	422.00
IUUC-Ggo-045531	Gorilla gorilla	96.98	0.00e+00	717.00
IUUC-Hsa-045802	Homo sapiens	94.61	0.00e+00	686.00
IUUC-Itr-048891	Ictidomys tridecemlineatus	74.17	2.00e-110	392.00
IUUC-Laf-053469	Loxodonta africana	67.35	7.00e-117	413.00
IUUC-Mcc-054662	Macaca mulatta	90.21	3.00e-175	607.00
IUUC-Meu-056499	Macropus eugenii	56.45	8.00e-93	333.00
IUUC-Mdo-062468	Monodelphis domestica	52.45	3.00e-98	351.00
IUUC-Mmu-064409	Mus musculus	49.41	3.00e-59	221.00
IUUC-Mpu-066553	Mustela putorius furo	71.02	5.00e-127	447.00
IUUC-Oan-073710	Ornithorhynchus anatinus	50.38	5.00e-66	244.00
IUUC-Pan-092278	Papio anubis	90.44	5.00e-177	613.00
IUUC-Pab-097537	Pongo abelii	91.38	5.00e-175	607.00
IUUC-Rno-104830	Rattus norvegicus	47.98	2.00e-53	202.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence