iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000019843.1	ENSONIT00000024998.1	ENSONIP00000024977.1
ENSONIG00000019843.1	ENSONIT00000024999.1	ENSONIP00000024978.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.20e-85	287.2	114	412

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl+N+gNtC++NS+LQcL+ +p+l++++l+++++k+      ep  ++++++q+ + ++  ++ ++++p  +l+ lk++a++f+  +q+
   Q: 114  GLQNMGNTCFLNSALQCLTYTPPLANYMLTREHSKTC----HEPGFCMMCTMQNHVIQVFANSGNVIKPIGVLNELKRIAKHFRYGSQE 198
           9*****************************5544444....36899******************************************* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           Da+Efl++ +d++++++          + +++          + +++ +s+i+++F+g l+s++kcl+c+ vs +++pfld++l+++  
   Q: 199  DAHEFLRYTVDAMQKSC----------LPGTK---------LDRQTQATSFIHQVFGGYLRSRVKCLNCKAVSDTFDPFLDITLEIKTA 268
           *****************..........32322.........46789999**************************************99 PP
   S: 180  eetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctsp 268
                 +++++Le+f+k+e+l+gen+y+c+kckk ++a+k++++++  +vL+l LkRf    ++ s  ki+k v++ ++Ldl+pf++++
   Q: 269  P-----NVSKALEQFVKPEQLDGENAYKCTKCKKMVTASKRFTIHRSANVLTLSLKRF----ANFSGGKITKDVKYLEHLDLRPFMSQS 348
           9.....9***************************************************....668899********999*********5 PP
   S: 269  eekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
           + +   ++ Y L+av+vHsG s++ GHY++y+k ++g+W++++Ds+V++++  +vl+   ++aYvlfY +
   Q: 349  QGE---PQLYGLYAVLVHSGfSCHAGHYFCYIKASNGQWYQMNDSSVSVSDIRTVLN---QQAYVLFYIK 412
           544...9**************************************************...********76 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MTIVDRSSEK SDHESAGCNR SSFTSRDVGM DGSCSSSWAV GPTVPSDSPR LKAPVGCLAP 60
TPGAAVYNST PSSVDRPKEQ VMCSGDGIDL PQKVLFSPDR LSLKWAQVHR IGAGLQNMGN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGATTCACG GTTTGCAGAG GAAGGTTGAA GAGCAGGAGG AAGAGATCAT GCAGCTGAGG 60
AGACGGATCA CTCAGCTCCA GACTTCACAA CTCACAGTTA ATTTCTCCGA GCTGGAAAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001055	Aegilops tauschii	41.40	3.00e-67	250.00
IUUC-Atr-003102	Amborella trichopoda	48.53	6.00e-88	319.00
IUUC-Apl-003459	Anas platyrhynchos	52.80	1.00e-146	514.00
IUUC-Aca-004440	Anolis carolinensis	57.56	0.00e+00	682.00
IUUC-Ame-011358	Astyanax mexicanus	73.91	0.00e+00	738.00
IUUC-Bta-012803	Bos taurus	58.29	0.00e+00	639.00
IUUC-Cja-019199	Callithrix jacchus	60.73	0.00e+00	642.00
IUUC-Cfa-020597	Canis familiaris	60.55	0.00e+00	635.00
IUUC-Cpo-021945	Cavia porcellus	60.73	0.00e+00	643.00
IUUC-Csa-023485	Chlorocebus sabaeus	61.14	0.00e+00	640.00
IUUC-Cho-024575	Choloepus hoffmanni	60.05	9.00e-132	465.00
IUUC-Dre-028442	Danio rerio	62.92	0.00e+00	793.00
IUUC-Dno-029673	Dasypus novemcinctus	61.72	0.00e+00	632.00
IUUC-Ete-033088	Echinops telfairi	72.26	1.00e-148	521.00
IUUC-Eca-033579	Equus caballus	61.06	0.00e+00	643.00
IUUC-Eeu-035019	Erinaceus europaeus	43.42	5.00e-74	270.00
IUUC-Fca-035792	Felis catus	60.59	0.00e+00	632.00
IUUC-Fal-037075	Ficedula albicollis	58.30	3.00e-166	580.00
IUUC-Gmo-038478	Gadus morhua	85.75	0.00e+00	700.00
IUUC-Gga-040504	Gallus gallus	57.97	6.00e-159	555.00
IUUC-Gma-044075	Glycine max	49.19	2.00e-86	313.00
IUUC-Ggo-044798	Gorilla gorilla	62.80	1.00e-159	558.00
IUUC-Hsa-046072	Homo sapiens	61.14	0.00e+00	639.00
IUUC-Hvu-047620	Hordeum vulgare	41.56	1.00e-69	258.00
IUUC-Itr-048078	Ictidomys tridecemlineatus	56.90	0.00e+00	659.00
IUUC-Lch-049867	Latimeria chalumnae	57.90	0.00e+00	711.00
IUUC-Loc-052621	Lepisosteus oculatus	68.51	0.00e+00	737.00
IUUC-Laf-054330	Loxodonta africana	60.37	0.00e+00	630.00
IUUC-Mla-059049	Melampsora laricipopulina	41.88	4.00e-61	229.00
IUUC-Mga-059501	Meleagris gallopavo	52.88	2.00e-142	500.00
IUUC-Mmr-060864	Microcebus murinus	56.92	0.00e+00	664.00
IUUC-Mdo-062395	Monodelphis domestica	62.25	0.00e+00	677.00
IUUC-Mmu-064236	Mus musculus	58.94	0.00e+00	636.00
IUUC-Mac-065039	Musa acuminata	45.24	1.00e-87	318.00
IUUC-Mpu-065822	Mustela putorius furo	61.05	0.00e+00	647.00
IUUC-Mlu-067091	Myotis lucifugus	59.64	1.00e-180	627.00
IUUC-Nle-069004	Nomascus leucogenys	61.14	0.00e+00	640.00
IUUC-Opr-071170	Ochotona princeps	71.17	2.00e-146	513.00
IUUC-Oan-073711	Ornithorhynchus anatinus	68.49	0.00e+00	647.00
IUUC-Ocu-074596	Oryctolagus cuniculus	60.88	0.00e+00	633.00
IUUC-Oga-088641	Otolemur garnettii	61.90	0.00e+00	649.00
IUUC-Oar-089760	Ovis aries	71.79	1.00e-177	617.00
IUUC-Ptr-091445	Pan troglodytes	61.14	0.00e+00	639.00
IUUC-Pan-092484	Papio anubis	61.14	0.00e+00	640.00
IUUC-Psi-093277	Pelodiscus sinensis	62.96	0.00e+00	665.00
IUUC-Pfo-096469	Poecilia formosa	62.87	0.00e+00	1199.00
IUUC-Pab-097794	Pongo abelii	67.83	0.00e+00	633.00
IUUC-Pva-103238	Pteropus vampyrus	54.70	3.00e-160	560.00
IUUC-Pgr-103270	Puccinia graminis	45.31	8.00e-69	255.00
IUUC-Rno-105068	Rattus norvegicus	60.77	0.00e+00	637.00
IUUC-Sha-106713	Sarcophilus harrisii	62.61	0.00e+00	688.00
IUUC-Sar-113340	Sorex araneus	65.85	1.00e-173	604.00
IUUC-Tgu-117149	Taeniopygia guttata	58.12	3.00e-165	576.00
IUUC-Tru-117776	Takifugu rubripes	60.04	0.00e+00	966.00
IUUC-Tsy-118974	Tarsius syrichta	66.32	0.00e+00	635.00
IUUC-Tni-120774	Tetraodon nigroviridis	82.07	0.00e+00	801.00
IUUC-Ttr-128764	Tursiops truncatus	54.48	9.00e-146	511.00
IUUC-Vvi-131535	Vitis vinifera	47.57	8.00e-88	318.00
IUUC-Xtr-132544	Xenopus tropicalis	53.31	2.00e-154	538.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence