iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-036169

Ensembl Protein ID

ENSFCAP00000001203.3

UniProt Accession

M3VWD9; M3VWD9_FELCA

Genbank Protein ID

ENSFCAP00000001203

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02023210

Gene Name

DDX58

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000001294.3	ENSFCAT00000001294.3	ENSFCAP00000001203.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	2.50e-45	152.9	2	74

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 2    deeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktL..vqkegWfrefl 73
           + e r+ l ++qd+v k+Ld+t++l+ y+s++++  e+++i a++++kg m+aa l+Lk+L  +q+egWfr+fl
   Q: 2    TAEERRNLRAFQDYVIKILDPTYILS-YMSPWFKDDEVQYIWAEKNNKGTMEAASLFLKFLleLQEEGWFRGFL 74
           5678999*******************.*********************************************96 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MTAEERRNLR AFQDYVIKIL DPTYILSYMS PWFKDDEVQY IWAEKNNKGT MEAASLFLKF 60
LLELQEEGWF RGFLDALAHA GYSGLYEAIE SWDFQTIERL EEYRSLLKRL QPEFKTTVNP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACGGCGG AGGAGAGGAG GAATCTGCGC GCCTTCCAGG ACTATGTCAT CAAGATTCTG 60
GACCCTACCT ATATCCTGAG CTACATGTCG CCCTGGTTTA AGGACGGTGA GTGGTCCCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR031964--CARD_dom
IPR011029--DEATH-like_dom
IPR006935--Helicase/UvrB_N
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00271--Helicase_C
PF04851--ResIII
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005923--C:bicellular tight junction
GO:0005829--C:cytosol
GO:0032587--C:ruffle membrane
GO:0005524--F:ATP binding
GO:0003690--F:double-stranded DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0009597--P:detection of virus
GO:0045087--P:innate immune response
GO:0002230--P:positive regulation of defense response to virus by host
GO:0032725--P:positive regulation of granulocyte macrophage colony-stimulating factor production
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0032755--P:positive regulation of interleukin-6 production
GO:0032757--P:positive regulation of interleukin-8 production
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0030334--P:regulation of cell migration
GO:0043330--P:response to exogenous dsRNA
GO:0039529--P:RIG-I signaling pathway

KEGG

fca:101095926

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001898	Ailuropoda melanoleuca	87.65	0.00e+00	1630.00
IUUC-Apl-003966	Anas platyrhynchos	52.09	0.00e+00	915.00
IUUC-Aca-004499	Anolis carolinensis	47.01	0.00e+00	805.00
IUUC-Ame-011950	Astyanax mexicanus	43.28	0.00e+00	704.00
IUUC-Bta-012489	Bos taurus	83.50	0.00e+00	1545.00
IUUC-Cel-018230	Caenorhabditis elegans	30.65	7.00e-75	275.00
IUUC-Cja-018716	Callithrix jacchus	81.10	0.00e+00	1531.00
IUUC-Cfa-020269	Canis familiaris	88.81	0.00e+00	1689.00
IUUC-Cpo-022507	Cavia porcellus	73.93	0.00e+00	1389.00
IUUC-Csa-024209	Chlorocebus sabaeus	82.38	0.00e+00	1554.00
IUUC-Cho-025104	Choloepus hoffmanni	69.86	0.00e+00	1294.00
IUUC-Cin-025792	Ciona intestinalis	32.75	7.00e-83	301.00
IUUC-Cgl-026385	Colletotrichum gloeosporioides	24.77	2.00e-20	95.90
IUUC-Dno-028954	Dasypus novemcinctus	79.18	0.00e+00	1450.00
IUUC-Eca-034039	Equus caballus	83.96	0.00e+00	1568.00
IUUC-Eeu-035009	Erinaceus europaeus	70.80	0.00e+00	937.00
IUUC-Fal-037579	Ficedula albicollis	53.82	0.00e+00	927.00
IUUC-Fso-038398	Fusarium solani	25.33	6.00e-19	90.50
IUUC-Ggo-045318	Gorilla gorilla	80.34	0.00e+00	1409.00
IUUC-Hsa-046671	Homo sapiens	82.49	0.00e+00	1524.00
IUUC-Itr-047996	Ictidomys tridecemlineatus	76.62	0.00e+00	1412.00
IUUC-Lch-050461	Latimeria chalumnae	50.05	0.00e+00	875.00
IUUC-Loc-052582	Lepisosteus oculatus	47.71	0.00e+00	835.00
IUUC-Laf-054324	Loxodonta africana	80.94	0.00e+00	1483.00
IUUC-Mcc-055390	Macaca mulatta	81.42	0.00e+00	1532.00
IUUC-Meu-056365	Macropus eugenii	62.90	5.00e-131	462.00
IUUC-Mpo-057328	Magnaporthe poae	23.94	4.00e-01	30.80
IUUC-Mmr-061407	Microcebus murinus	80.77	0.00e+00	1550.00
IUUC-Mmu-063939	Mus musculus	74.27	0.00e+00	1380.00
IUUC-Mpu-066226	Mustela putorius furo	88.21	0.00e+00	1561.00
IUUC-Mlu-068092	Myotis lucifugus	84.91	0.00e+00	1546.00
IUUC-Nfi-068405	Neosartorya fischeri	23.69	1.00e-21	99.00
IUUC-Opr-070246	Ochotona princeps	66.86	0.00e+00	680.00
IUUC-Oan-072742	Ornithorhynchus anatinus	60.56	0.00e+00	967.00
IUUC-Ocu-073959	Oryctolagus cuniculus	75.24	0.00e+00	1415.00
IUUC-Oga-089173	Otolemur garnettii	80.88	0.00e+00	1504.00
IUUC-Oar-089369	Ovis aries	82.96	0.00e+00	1511.00
IUUC-Ptr-091032	Pan troglodytes	82.49	0.00e+00	1524.00
IUUC-Pan-092383	Papio anubis	81.85	0.00e+00	1539.00
IUUC-Psi-093432	Pelodiscus sinensis	56.38	0.00e+00	1066.00
IUUC-Pma-094367	Petromyzon marinus	41.58	8.00e-114	404.00
IUUC-Pab-098416	Pongo abelii	82.63	0.00e+00	1429.00
IUUC-Pca-101006	Procavia capensis	79.75	0.00e+00	668.00
IUUC-Pva-102966	Pteropus vampyrus	84.70	0.00e+00	1591.00
IUUC-Pgr-103529	Puccinia graminis	26.51	2.00e-26	115.00
IUUC-Rno-105059	Rattus norvegicus	75.38	0.00e+00	919.00
IUUC-Ssl-108450	Sclerotinia sclerotiorum	28.57	2.00e-04	43.10
IUUC-Sar-113202	Sorex araneus	67.70	0.00e+00	1055.00
IUUC-Ssc-116120	Sus scrofa	82.42	0.00e+00	1509.00
IUUC-Tgu-117314	Taeniopygia guttata	53.09	0.00e+00	951.00
IUUC-Tsy-119453	Tarsius syrichta	81.18	0.00e+00	870.00
IUUC-Tre-122194	Trichoderma reesei	25.33	2.00e-18	89.00
IUUC-Ttr-128421	Tursiops truncatus	80.92	0.00e+00	1269.00
IUUC-Vpa-130602	Vicugna pacos	81.86	0.00e+00	1467.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence