iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Vvi-131116

UUCD1 version

UUC-ViV-01147

Ensembl Protein ID

VIT_19s0014g03920.t01

UniProt Accession

F6H2F7; F6H2F7_VITVI

Genbank Protein ID

CCB46401.1

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

FN595229

Gene Name

VIT_19s0014g03920

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
VIT_19s0014g03920	VIT_19s0014g03920.t01	VIT_19s0014g03920.t01

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.40e-53	182.8	312	809
UBD/Alpha-Helix/UBA	4.60e-16	58.9	624	663

Active Site

Position(s)	Description	Evidence
321	Nucleophile	{ECO:0000256\|PIRSR:PIRSR016308-1}
772	Proton acceptor	{ECO:0000256\|PIRSR:PIRSR016308-1}

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelre.lllekkkeklneenpkepkgellkslqklfeel.....................w.kskk 65
           tGl NlgN+CY+ S++Q+ ++++++ + ++l++  ++  e++p +p+ +l ++l+kl + +                     + +sk+
   Q: 312  TGLVNLGNSCYLASTMQVVFSTQSFHSrYYLSQSLKAAFETAPADPTVDLNMQLTKLAHGMlsgkysfpasekidianaaapMsSSKQ 399
           7************************7526666777777788999*****************999999999999999887766269999 PP
   S: 66   kavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksq 153
           + + pr++++++++ ++efs+++qqDa Ef+ +lldq+e+                               + +   s+ F++ ++++
   Q: 400  EGIPPRMFKAVIAASHPEFSSMRQQDALEFFLHLLDQVERVN---------------------------AGHPELDPSRSFKFGIEER 460
           9*************************************9977...........................33444557899******** PP
   S: 154  ikclecdnvssreepfldlslpvpgkeetkke.............................slqdcLesftkeeelegenkyycekck 212
           + c++ +  ++r+ + + lsl++p +e t+k                               l+ cL+sf+++ee++g   +y++  k
   Q: 461  LFCPSGKVAYNRRGD-YILSLNIPLHEATNKDqleafnklkaekkaegkevsgdeivrprvPLEACLASFSAPEEVHG---FYSTALK 544
           ****99888866654.5666666666665555679******************************************9...******* PP
   S: 213  kkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts................................. 267
            k++a+k+ +l+++P++L+lh+ +f + ee+++++k++ ++++p+ +d+s++ ++                                 
   Q: 545  TKTTAVKTAGLTSFPDYLVLHMRKF-VMEEGWVPKKLDVYIDVPDIIDISHMRSRgiqpgeellpeavdegkvesekllaneeivaql 631
           *************************.67889*******************99999999999999999988888888888888888888 PP
   S: 268  ................................................peekqke................................. 274
                                                                 e                                 
   Q: 632  vsmgfnhlhcqkaaintsnagveeamnwllshmddpdidfpisqeaenA-----Ealsfvdqskvdtlisfgfqedisrralrasggd 714
           8888877777777777776666666666666666666666665555440.....1555666666666666666666666666677777 PP
   S: 275  .....................................kkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevle 324
                                                  +Y+Li+ v+H G s+++GHYva++++ +g+W+ f+D+kV ++   +  +
   Q: 715  iekatdwifsnpdaasssdmdattsstptadaglpdgGGRYRLIGLVSHIGtSTQCGHYVAHIYK-DGRWVIFNDDKVGAS--INPPK 799
           77777777777777777788888888899999999999***************************.9***********988..34455 PP
   S: 325  etgstaYvlfYkr 337
              + +Y++f++r
   Q: 800  ---DMGYLYFFER 809
           ...7888888876 PP

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
           +e++++qlv+MGF+  ++++a  ++ n  +e+A+++Ll++
   Q: 624  NEEIVAQLVSMGFNHLHCQKAAINTsNAGVEEAMNWLLSH 663
           89************************************97 PP

Organism

Vitis vinifera

Protein Sequence
(Fasta)

MLDPMDLLRS NLSRVRIPEP TNRIYKQECC VSFATPKSEG GLFIDMSTFL AFGKDCVDWN 60
YEKTGNPVYL HIKQTKKLVP EDRPLKKPTL LAIGVDGGFD NNEPEYEEAH NIVILPSYVS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAGCTTAGGG CAAAGAACCT ATTCTCCTCC CCTCCTCTTT ATCTCTTTGA AACGCGGCGT 60
CTTGTCCAGA GAATGTTGGA CCCCATGGAC CTCCTTCGAT CCAACCTCTC TCGTGTCCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

vvi:100264052

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000394	Aegilops tauschii	66.75	0.00e+00	1054.00
IUUC-Aml-002104	Ailuropoda melanoleuca	47.32	0.00e+00	742.00
IUUC-Atr-002580	Amborella trichopoda	71.73	0.00e+00	1245.00
IUUC-Apl-003774	Anas platyrhynchos	47.64	0.00e+00	733.00
IUUC-Aca-005368	Anolis carolinensis	48.28	0.00e+00	773.00
IUUC-Aly-005727	Arabidopsis lyrata	76.24	0.00e+00	1270.00
IUUC-Ath-006974	Arabidopsis thaliana	76.49	0.00e+00	1271.00
IUUC-Ago-007890	Ashbya gossypii	27.00	6.00e-70	258.00
IUUC-Acl-008057	Aspergillus clavatus	34.55	3.00e-121	428.00
IUUC-Afl-008547	Aspergillus flavus	35.88	2.00e-110	392.00
IUUC-Afu-008805	Aspergillus fumigatus	34.50	2.00e-107	382.00
IUUC-Ani-009441	Aspergillus nidulans	34.83	4.00e-97	348.00
IUUC-Ang-009720	Aspergillus niger	34.43	7.00e-110	390.00
IUUC-Aor-010111	Aspergillus oryzae	33.66	6.00e-119	421.00
IUUC-Ate-010531	Aspergillus terreus	32.84	3.00e-100	358.00
IUUC-Ame-011470	Astyanax mexicanus	41.70	0.00e+00	653.00
IUUC-Bgr-012183	Blumeria graminis	31.64	2.00e-106	379.00
IUUC-Bta-013179	Bos taurus	47.31	0.00e+00	743.00
IUUC-Bci-013858	Botrytis cinerea	33.45	7.00e-121	427.00
IUUC-Bdi-014904	Brachypodium distachyon	71.15	0.00e+00	1157.00
IUUC-Bol-015536	Brassica oleracea	76.64	0.00e+00	1268.00
IUUC-Bra-017939	Brassica rapa	76.70	0.00e+00	1272.00
IUUC-Cel-018625	Caenorhabditis elegans	33.02	9.00e-114	403.00
IUUC-Cja-019063	Callithrix jacchus	47.09	0.00e+00	739.00
IUUC-Cfa-020976	Canis familiaris	48.63	0.00e+00	758.00
IUUC-Cpo-022265	Cavia porcellus	48.39	0.00e+00	760.00
IUUC-Cre-022640	Chlamydomonas reinhardtii	40.99	8.00e-117	413.00
IUUC-Csa-024177	Chlorocebus sabaeus	47.92	0.00e+00	671.00
IUUC-Cho-024702	Choloepus hoffmanni	41.59	8.00e-116	410.00
IUUC-Cin-025411	Ciona intestinalis	42.87	6.00e-179	620.00
IUUC-Csv-026347	Ciona savignyi	40.83	4.00e-175	607.00
IUUC-Cgl-026667	Colletotrichum gloeosporioides	34.27	3.00e-108	385.00
IUUC-Cne-026831	Cryptococcus neoformans	35.25	1.00e-117	416.00
IUUC-Cme-027335	Cyanidioschyzon merolae	34.43	6.00e-38	152.00
IUUC-Dre-027982	Danio rerio	43.75	0.00e+00	655.00
IUUC-Dno-029034	Dasypus novemcinctus	47.31	0.00e+00	748.00
IUUC-Dor-030130	Dipodomys ordii	38.75	1.00e-108	386.00
IUUC-Dse-031467	Dothistroma septosporum	34.71	6.00e-117	414.00
IUUC-Dme-032075	Drosophila melanogaster	43.35	0.00e+00	659.00
IUUC-Ete-032865	Echinops telfairi	43.87	0.00e+00	660.00
IUUC-Eca-034059	Equus caballus	47.56	0.00e+00	747.00
IUUC-Eeu-035304	Erinaceus europaeus	45.33	0.00e+00	673.00
IUUC-Fca-035515	Felis catus	47.43	0.00e+00	747.00
IUUC-Fal-037271	Ficedula albicollis	48.57	0.00e+00	723.00
IUUC-Fox-037745	Fusarium oxysporum	35.76	2.00e-122	432.00
IUUC-Fso-038158	Fusarium solani	34.68	2.00e-117	415.00
IUUC-Gmo-039071	Gadus morhua	44.19	0.00e+00	661.00
IUUC-Ggr-040098	Gaeumannomyces graminis	33.41	3.00e-111	395.00
IUUC-Gga-040635	Gallus gallus	47.56	0.00e+00	766.00
IUUC-Gac-042528	Gasterosteus aculeatus	43.58	0.00e+00	672.00
IUUC-Gma-043614	Glycine max	80.76	0.00e+00	1288.00
IUUC-Ggo-044602	Gorilla gorilla	47.55	0.00e+00	749.00
IUUC-Hsa-045959	Homo sapiens	47.55	0.00e+00	749.00
IUUC-Hvu-047563	Hordeum vulgare	70.52	0.00e+00	912.00
IUUC-Itr-048712	Ictidomys tridecemlineatus	47.55	0.00e+00	751.00
IUUC-Kpa-049156	Komagataella pastoris	30.94	2.00e-102	365.00
IUUC-Lch-049648	Latimeria chalumnae	47.31	0.00e+00	746.00
IUUC-Lpe-051523	Leersia perrieri	69.10	0.00e+00	1148.00
IUUC-Loc-052072	Lepisosteus oculatus	42.19	0.00e+00	653.00
IUUC-Lma-053216	Leptosphaeria maculans	35.22	1.00e-111	397.00
IUUC-Laf-054327	Loxodonta africana	47.43	0.00e+00	750.00
IUUC-Mcc-055443	Macaca mulatta	47.66	0.00e+00	753.00
IUUC-Meu-056298	Macropus eugenii	49.83	2.00e-153	535.00
IUUC-Mor-057106	Magnaporthe oryzae	34.27	2.00e-120	426.00
IUUC-Mpo-057589	Magnaporthe poae	33.13	4.00e-113	401.00
IUUC-Mtr-058680	Medicago truncatula	81.68	0.00e+00	1333.00
IUUC-Mla-058903	Melampsora laricipopulina	34.13	1.00e-108	386.00
IUUC-Mga-059669	Meleagris gallopavo	47.54	0.00e+00	729.00
IUUC-Mvi-060476	Microbotryum violaceum	33.85	3.00e-103	368.00
IUUC-Mmr-060575	Microcebus murinus	47.43	0.00e+00	747.00
IUUC-Mdo-062183	Monodelphis domestica	47.68	0.00e+00	753.00
IUUC-Mmu-063592	Mus musculus	47.55	0.00e+00	750.00
IUUC-Mac-065446	Musa acuminata	70.51	0.00e+00	1204.00
IUUC-Mpu-066082	Mustela putorius furo	48.63	0.00e+00	758.00
IUUC-Mlu-067345	Myotis lucifugus	47.21	0.00e+00	738.00
IUUC-Nfi-068558	Neosartorya fischeri	35.04	2.00e-118	419.00
IUUC-Ncr-068960	Neurospora crassa	32.32	2.00e-103	369.00
IUUC-Nle-070173	Nomascus leucogenys	48.63	0.00e+00	758.00
IUUC-Opr-070556	Ochotona princeps	47.78	0.00e+00	761.00
IUUC-Ont-071502	Oreochromis niloticus	45.38	0.00e+00	678.00
IUUC-Oan-072959	Ornithorhynchus anatinus	54.75	7.00e-69	252.00
IUUC-Ocu-074861	Oryctolagus cuniculus	48.75	0.00e+00	766.00
IUUC-Oba-075109	Oryza barthii	70.74	0.00e+00	1163.00
IUUC-Obr-076292	Oryza brachyantha	71.89	0.00e+00	1146.00
IUUC-Ogl-077065	Oryza glaberrima	72.35	0.00e+00	1203.00
IUUC-Ogu-078776	Oryza glumaepatula	70.49	0.00e+00	1172.00
IUUC-Oin-080048	Oryza indica	71.85	0.00e+00	1185.00
IUUC-Olo-080711	Oryza longistaminata	69.08	0.00e+00	1075.00
IUUC-Ome-081506	Oryza meridionalis	70.48	0.00e+00	1083.00
IUUC-Oni-082320	Oryza nivara	68.79	0.00e+00	1154.00
IUUC-Opu-083801	Oryza punctata	71.48	0.00e+00	1138.00
IUUC-Oru-085139	Oryza rufipogon	68.67	0.00e+00	1148.00
IUUC-Osa-085713	Oryza sativa	72.47	0.00e+00	1206.00
IUUC-Ola-086951	Oryzias latipes	42.68	0.00e+00	650.00
IUUC-Olu-087822	Ostreococcus lucimarinus	39.78	6.00e-163	567.00
IUUC-Oga-088625	Otolemur garnettii	47.37	0.00e+00	749.00
IUUC-Oar-089995	Ovis aries	47.26	0.00e+00	737.00
IUUC-Ptr-090640	Pan troglodytes	46.96	0.00e+00	749.00
IUUC-Pan-091974	Papio anubis	47.44	0.00e+00	747.00
IUUC-Psi-093957	Pelodiscus sinensis	47.56	0.00e+00	776.00
IUUC-Pma-094242	Petromyzon marinus	48.34	2.00e-105	374.00
IUUC-Pno-094835	Phaeosphaeria nodorum	37.09	9.00e-109	387.00
IUUC-Ppa-095901	Physcomitrella patens	64.79	0.00e+00	1095.00
IUUC-Pfo-097148	Poecilia formosa	45.04	0.00e+00	677.00
IUUC-Pab-098068	Pongo abelii	43.52	4.00e-180	624.00
IUUC-Pop-098855	Populus trichocarpa	83.11	0.00e+00	1309.00
IUUC-Pca-100738	Procavia capensis	44.99	3.00e-143	501.00
IUUC-Ppe-101315	Prunus persica	84.15	0.00e+00	1390.00
IUUC-Pva-102154	Pteropus vampyrus	46.97	0.00e+00	735.00
IUUC-Pgr-103343	Puccinia graminis	34.36	9.00e-102	363.00
IUUC-Ptt-103928	Puccinia triticina	29.50	2.00e-93	336.00
IUUC-Pte-104306	Pyrenophora teres	35.29	3.00e-104	372.00
IUUC-Pyt-104696	Pyrenophora triticirepentis	35.01	4.00e-110	391.00
IUUC-Rno-105801	Rattus norvegicus	47.66	0.00e+00	751.00
IUUC-Sce-106304	Saccharomyces cerevisiae	30.58	9.00e-67	247.00
IUUC-Sha-107635	Sarcophilus harrisii	47.73	0.00e+00	746.00
IUUC-Sja-107678	Schizosaccharomyces japonicus	32.51	8.00e-94	337.00
IUUC-Spo-108144	Schizosaccharomyces pombe	33.95	2.00e-112	399.00
IUUC-Smo-108848	Selaginella moellendorffii	61.32	0.00e+00	976.00
IUUC-Sit-110728	Setaria italica	72.13	0.00e+00	1213.00
IUUC-Sly-111523	Solanum lycopersicum	77.97	0.00e+00	1332.00
IUUC-Sar-113733	Sorex araneus	45.99	4.00e-96	345.00
IUUC-Sbi-114419	Sorghum bicolor	72.75	0.00e+00	1207.00
IUUC-Sre-115225	Sporisorium reilianum	32.19	8.00e-108	384.00
IUUC-Ssc-115686	Sus scrofa	47.08	0.00e+00	746.00
IUUC-Tgu-117346	Taeniopygia guttata	47.39	0.00e+00	745.00
IUUC-Tru-118350	Takifugu rubripes	42.84	0.00e+00	660.00
IUUC-Tsy-119278	Tarsius syrichta	39.49	2.00e-166	578.00
IUUC-Tni-120658	Tetraodon nigroviridis	42.79	0.00e+00	643.00
IUUC-Tca-121585	Theobroma cacao	82.43	0.00e+00	1330.00
IUUC-Tre-122043	Trichoderma reesei	34.88	4.00e-113	401.00
IUUC-Tvi-122303	Trichoderma virens	34.31	2.00e-115	408.00
IUUC-Tae-123798	Triticum aestivum	71.15	0.00e+00	1171.00
IUUC-Tur-126732	Triticum urartu	66.71	0.00e+00	1099.00
IUUC-Tme-126909	Tuber melanosporum	33.37	4.00e-105	374.00
IUUC-Tbe-127261	Tupaia belangeri	39.90	7.00e-118	417.00
IUUC-Ttr-128295	Tursiops truncatus	38.40	2.00e-163	568.00
IUUC-Uma-129599	Ustilago maydis	33.30	1.00e-112	399.00
IUUC-Vda-129688	Verticillium dahliae	34.64	2.00e-113	402.00
IUUC-Vpa-130170	Vicugna pacos	37.50	1.00e-147	516.00
IUUC-Xtr-131953	Xenopus tropicalis	46.42	0.00e+00	724.00
IUUC-Xma-133837	Xiphophorus maculatus	45.15	0.00e+00	679.00
IUUC-Yli-134510	Yarrowia lipolytica	33.62	2.00e-105	375.00
IUUC-Zma-135786	Zea mays	71.02	0.00e+00	1160.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence