iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cja-019911

Ensembl Protein ID

ENSCJAP00000017595.2

UniProt Accession

F7I7M0; F7I7M0_CALJA

Genbank Protein ID

ENSCJAP00000017595

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACFV01033365

Gene Name

OPTN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000009575.2	ENSCJAT00000018610.2	ENSCJAP00000017595.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBAN	3.20e-25	88.8	454	513

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBAN

   S: 1    keelletvevLkqQveiYkeDFqaERadRErlneekeeLqeqveklqkqvsklndslkas 60
           +ee+let+ +L++Q+e+Y++DF+aERa+RE+++eeke+L+ q+++l+k+++ ++d++++s
   Q: 454  QEEDLETMSILRAQMEVYCSDFHAERAAREKIHEEKEQLALQLAVLLKENDVFEDGGRQS 513
           79*******************************************************998 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MSHQPLSCLT EKGASPSEST GNGPPHLAHP NLDTFTPEEL LQQMKELLTE NHQLKEAMKL 60
NNQAMKGRFE ELSAWTEKQK EERQFFETQS KEAKERLMAL SQENEKLKEE LGKLKGKSER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCTCCCCGA GCCCCGCTGT CCCCGCCGCC CCGCAGCAGG TGCCCTGGTC ATCATCACAA 60
CCCGGTCCGG AGCCCTCTCC CGGCGGCATG ATGCCGAGGA AACAGTGACC CTGAGCGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032419--CC2-LZ_dom
IPR021063--NEMO_N
IPR032939--Optineurin
IPR034735--ZF_CCHC_NOA

PROSITE

PS51801--ZF_CCHC_NOA

Pfam

PF16516--CC2-LZ
PF11577--NEMO

Gene Ontology

GO:0031410--C:cytoplasmic vesicle
GO:0005829--C:cytosol
GO:0048471--C:perinuclear region of cytoplasm
GO:0005802--C:trans-Golgi network
GO:0050829--P:defense response to Gram-negative bacterium
GO:0090161--P:Golgi ribbon formation
GO:0043001--P:Golgi to plasma membrane protein transport
GO:0016236--P:macroautophagy
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0001920--P:negative regulation of receptor recycling
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:1904417--P:positive regulation of xenophagy
GO:0000042--P:protein targeting to Golgi

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002037	Ailuropoda melanoleuca	80.77	0.00e+00	782.00
IUUC-Apl-003812	Anas platyrhynchos	56.31	4.00e-150	524.00
IUUC-Aca-004625	Anolis carolinensis	55.27	4.00e-146	511.00
IUUC-Aly-005781	Arabidopsis lyrata	55.00	2.10e-02	33.50
IUUC-Ame-011116	Astyanax mexicanus	37.50	5.00e-72	265.00
IUUC-Bta-013240	Bos taurus	83.07	0.00e+00	898.00
IUUC-Cfa-020330	Canis familiaris	83.62	0.00e+00	831.00
IUUC-Cpo-021753	Cavia porcellus	80.41	0.00e+00	809.00
IUUC-Csa-023662	Chlorocebus sabaeus	94.97	0.00e+00	977.00
IUUC-Cho-024574	Choloepus hoffmanni	68.43	1.00e-130	459.00
IUUC-Cme-027299	Cyanidioschyzon merolae	35.96	3.00e-03	37.00
IUUC-Dre-027720	Danio rerio	41.87	4.00e-94	338.00
IUUC-Dno-029079	Dasypus novemcinctus	79.31	0.00e+00	771.00
IUUC-Dor-030890	Dipodomys ordii	80.48	0.00e+00	830.00
IUUC-Ete-032568	Echinops telfairi	81.11	0.00e+00	743.00
IUUC-Eca-033528	Equus caballus	83.76	0.00e+00	847.00
IUUC-Eeu-035219	Erinaceus europaeus	74.61	0.00e+00	809.00
IUUC-Fca-035852	Felis catus	83.11	0.00e+00	834.00
IUUC-Fal-036862	Ficedula albicollis	59.43	8.00e-149	520.00
IUUC-Gmo-038735	Gadus morhua	40.84	9.00e-80	290.00
IUUC-Gga-040939	Gallus gallus	56.99	1.00e-152	533.00
IUUC-Gac-041580	Gasterosteus aculeatus	44.22	5.00e-98	351.00
IUUC-Ggo-045034	Gorilla gorilla	83.71	0.00e+00	887.00
IUUC-Hsa-046624	Homo sapiens	93.93	0.00e+00	1001.00
IUUC-Itr-048288	Ictidomys tridecemlineatus	78.35	0.00e+00	816.00
IUUC-Lch-049720	Latimeria chalumnae	49.49	8.00e-82	297.00
IUUC-Loc-052185	Lepisosteus oculatus	46.66	1.00e-107	383.00
IUUC-Laf-054079	Loxodonta africana	82.66	0.00e+00	827.00
IUUC-Mcc-055674	Macaca mulatta	94.28	0.00e+00	953.00
IUUC-Meu-056769	Macropus eugenii	83.93	2.00e-74	273.00
IUUC-Mga-060203	Meleagris gallopavo	57.27	3.00e-144	504.00
IUUC-Mmr-061492	Microcebus murinus	85.34	0.00e+00	843.00
IUUC-Mdo-063051	Monodelphis domestica	75.30	0.00e+00	793.00
IUUC-Mmu-063409	Mus musculus	76.99	0.00e+00	857.00
IUUC-Mpu-065907	Mustela putorius furo	77.27	0.00e+00	817.00
IUUC-Mlu-066957	Myotis lucifugus	82.93	0.00e+00	784.00
IUUC-Nle-069973	Nomascus leucogenys	93.41	0.00e+00	984.00
IUUC-Opr-071049	Ochotona princeps	77.55	0.00e+00	734.00
IUUC-Ont-071915	Oreochromis niloticus	44.08	1.00e-94	340.00
IUUC-Oan-072965	Ornithorhynchus anatinus	71.65	0.00e+00	761.00
IUUC-Ocu-074029	Oryctolagus cuniculus	74.95	0.00e+00	683.00
IUUC-Ola-087019	Oryzias latipes	42.52	8.00e-93	334.00
IUUC-Oga-088613	Otolemur garnettii	86.57	0.00e+00	878.00
IUUC-Oar-090386	Ovis aries	83.07	0.00e+00	894.00
IUUC-Ptr-091619	Pan troglodytes	94.11	0.00e+00	1001.00
IUUC-Pan-092178	Papio anubis	94.14	0.00e+00	958.00
IUUC-Psi-093214	Pelodiscus sinensis	63.21	6.00e-171	593.00
IUUC-Pfo-096901	Poecilia formosa	41.58	2.00e-86	312.00
IUUC-Pab-097560	Pongo abelii	85.10	0.00e+00	863.00
IUUC-Pca-100853	Procavia capensis	76.20	1.00e-127	449.00
IUUC-Pva-102255	Pteropus vampyrus	82.73	0.00e+00	783.00
IUUC-Rno-105812	Rattus norvegicus	79.22	0.00e+00	850.00
IUUC-Sha-107225	Sarcophilus harrisii	79.68	1.00e-157	548.00
IUUC-Sar-113736	Sorex araneus	73.77	7.00e-131	460.00
IUUC-Ssc-115422	Sus scrofa	83.45	0.00e+00	873.00
IUUC-Tgu-116924	Taeniopygia guttata	59.31	2.00e-150	525.00
IUUC-Tru-117695	Takifugu rubripes	38.62	4.00e-90	325.00
IUUC-Tsy-119090	Tarsius syrichta	84.92	1.00e-156	546.00
IUUC-Tni-120645	Tetraodon nigroviridis	41.38	2.00e-92	333.00
IUUC-Tbe-127970	Tupaia belangeri	68.39	0.00e+00	662.00
IUUC-Ttr-129244	Tursiops truncatus	83.42	0.00e+00	826.00
IUUC-Vpa-130313	Vicugna pacos	81.87	0.00e+00	791.00
IUUC-Xtr-132115	Xenopus tropicalis	44.42	6.00e-101	361.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence