iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-054483

Ensembl Protein ID

ENSLAFP00000024076.1

UniProt Accession

G3U8B8; G3U8B8_LOXAF

Protein Name

Uncharacterized protein

Gene Name

PPARG

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000030870.1	ENSLAFT00000029258.1	ENSLAFP00000024076.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	96.04	0.00e+00	974.00	IUUC-Hsa-046916

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MGETLGDSLI DPESCCFSDT LSASTSQGIT MVDTEMPFWP TNFGISSMDL SVMDDHSHSF 60
DIKPFTTVDF SSISTPHYED IPFTRADPVM TDYKYDLKLQ DYQSAIKVEP ASPPYYSEKT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGTGAAA CTCTGGGAGA TTCTCTCATT GACCCTGAGA GCTGTTGCTT CAGTGATACA 60
CTGTCTGCAA GCACTTCACA AGGTAAAGTC TGTTCTAGAA AGGGCTATTT GGGATATTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0675--Receptor
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003074--1Cnucl_rcpt
IPR003077--1Cnucl_rcpt_G
IPR000536--Nucl_hrmn_rcpt_lig-bd
IPR001723--Nuclear_hrmn_rcpt
IPR022590--PPARgamma_N
IPR001628--Znf_hrmn_rcpt
IPR013088--Znf_NHR/GATA

PROSITE

PS00031--NUCLEAR_REC_DBD_1
PS51030--NUCLEAR_REC_DBD_2

Pfam

PF00104--Hormone_recep
PF12577--PPARgamma_N
PF00105--zf-C4

PRINTS

PR01288--PROXISOMEPAR
PR01291--PROXISOMPAGR
PR00398--STRDHORMONER
PR00047--STROIDFINGER

SMART

SM00430--HOLI
SM00399--ZnF_C4

Gene Ontology

GO:0090575--C:RNA polymerase II transcription factor complex
GO:0008144--F:drug binding
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0004879--F:RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
GO:0043565--F:sequence-specific DNA binding
GO:0003707--F:steroid hormone receptor activity
GO:0044212--F:transcription regulatory region DNA binding
GO:0008270--F:zinc ion binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0048469--P:cell maturation
GO:0032869--P:cellular response to insulin stimulus
GO:0042593--P:glucose homeostasis
GO:0042953--P:lipoprotein transport
GO:0045713--P:low-density lipoprotein particle receptor biosynthetic process
GO:0010742--P:macrophage derived foam cell differentiation
GO:0030224--P:monocyte differentiation
GO:0010887--P:negative regulation of cholesterol storage
GO:0060336--P:negative regulation of interferon-gamma-mediated signaling pathway
GO:0010745--P:negative regulation of macrophage derived foam cell differentiation
GO:0010871--P:negative regulation of receptor biosynthetic process
GO:0010891--P:negative regulation of sequestering of triglyceride
GO:0048662--P:negative regulation of smooth muscle cell proliferation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0035357--P:peroxisome proliferator activated receptor signaling pathway
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0008217--P:regulation of blood pressure
GO:0055098--P:response to low-density lipoprotein particle
GO:0032526--P:response to retinoic acid
GO:0006351--P:transcription, DNA-templated

KEGG

lav:100654408

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001214	Ailuropoda melanoleuca	94.06	0.00e+00	954.00
IUUC-Aca-005129	Anolis carolinensis	87.73	0.00e+00	869.00
IUUC-Ame-010818	Astyanax mexicanus	65.99	0.00e+00	641.00
IUUC-Bta-013226	Bos taurus	94.65	0.00e+00	965.00
IUUC-Cja-019236	Callithrix jacchus	96.04	0.00e+00	979.00
IUUC-Cfa-020281	Canis familiaris	96.63	0.00e+00	986.00
IUUC-Cpo-021587	Cavia porcellus	94.76	0.00e+00	917.00
IUUC-Csa-023400	Chlorocebus sabaeus	97.47	0.00e+00	936.00
IUUC-Cho-024593	Choloepus hoffmanni	85.54	0.00e+00	849.00
IUUC-Dre-028176	Danio rerio	61.05	1.00e-152	532.00
IUUC-Dno-029063	Dasypus novemcinctus	92.48	0.00e+00	939.00
IUUC-Ete-032520	Echinops telfairi	93.07	0.00e+00	940.00
IUUC-Eeu-034683	Erinaceus europaeus	51.56	9.00e-14	71.20
IUUC-Fca-035935	Felis catus	96.44	0.00e+00	984.00
IUUC-Fal-037524	Ficedula albicollis	91.58	0.00e+00	880.00
IUUC-Gga-041223	Gallus gallus	92.42	0.00e+00	885.00
IUUC-Gac-042156	Gasterosteus aculeatus	62.52	0.00e+00	640.00
IUUC-Ggo-045265	Gorilla gorilla	95.64	0.00e+00	976.00
IUUC-Hsa-046916	Homo sapiens	96.04	0.00e+00	978.00
IUUC-Lch-049759	Latimeria chalumnae	80.05	0.00e+00	676.00
IUUC-Loc-051870	Lepisosteus oculatus	73.35	0.00e+00	742.00
IUUC-Meu-056587	Macropus eugenii	93.20	0.00e+00	909.00
IUUC-Mga-059530	Meleagris gallopavo	92.42	0.00e+00	885.00
IUUC-Mmr-060576	Microcebus murinus	94.26	0.00e+00	962.00
IUUC-Mdo-061854	Monodelphis domestica	97.05	0.00e+00	928.00
IUUC-Mmu-063724	Mus musculus	94.46	0.00e+00	966.00
IUUC-Mpu-066888	Mustela putorius furo	97.05	0.00e+00	964.00
IUUC-Mlu-067978	Myotis lucifugus	96.04	0.00e+00	1010.00
IUUC-Nle-070069	Nomascus leucogenys	96.04	0.00e+00	978.00
IUUC-Opr-070630	Ochotona princeps	92.43	0.00e+00	783.00
IUUC-Ont-071399	Oreochromis niloticus	59.56	1.00e-180	625.00
IUUC-Ocu-074862	Oryctolagus cuniculus	95.60	0.00e+00	925.00
IUUC-Ola-087266	Oryzias latipes	56.05	7.00e-159	553.00
IUUC-Oga-089143	Otolemur garnettii	94.46	0.00e+00	967.00
IUUC-Oar-089725	Ovis aries	94.65	0.00e+00	964.00
IUUC-Ptr-091580	Pan troglodytes	95.84	0.00e+00	977.00
IUUC-Psi-093041	Pelodiscus sinensis	90.38	0.00e+00	867.00
IUUC-Pfo-097438	Poecilia formosa	58.74	8.00e-178	616.00
IUUC-Pab-098333	Pongo abelii	96.44	0.00e+00	924.00
IUUC-Pca-100861	Procavia capensis	98.11	0.00e+00	944.00
IUUC-Pva-102186	Pteropus vampyrus	86.34	0.00e+00	857.00
IUUC-Rno-105583	Rattus norvegicus	94.46	0.00e+00	966.00
IUUC-Sha-107484	Sarcophilus harrisii	95.09	0.00e+00	934.00
IUUC-Sar-112996	Sorex araneus	84.04	0.00e+00	638.00
IUUC-Ssc-115945	Sus scrofa	96.04	0.00e+00	975.00
IUUC-Tsy-119098	Tarsius syrichta	86.73	0.00e+00	852.00
IUUC-Tni-120902	Tetraodon nigroviridis	61.49	5.00e-174	603.00
IUUC-Tbe-127225	Tupaia belangeri	73.66	0.00e+00	694.00
IUUC-Ttr-129292	Tursiops truncatus	96.24	0.00e+00	979.00
IUUC-Vpa-130378	Vicugna pacos	90.16	0.00e+00	774.00
IUUC-Xtr-132171	Xenopus tropicalis	31.98	9.00e-17	81.60

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence