iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tbe-127225

Ensembl Protein ID

ENSTBEP00000009744.1

UniProt Accession

L7P7H9; L7P7H9_TUPBE

Genbank Protein ID

AFP75244.1

Protein Name

Peroxisome proliferator-activated receptor alpha

Genbank Nucleotide ID

JX444170

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTBEG00000011278.1	ENSTBET00000011274.1	ENSTBEP00000009744.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	75.64	0.00e+00	715.00	IUUC-Hsa-046916

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Tupaia belangeri

Protein Sequence
(Fasta)

MGETLGVSPV DLGGDSFPDT LSASTSQEVT MVDTEMPFWP TNFGISSVDL SVMDDPSHSF 60
DIKPFTTVDF SSISAPHYED IPFPRADPMV ADYKYDLKLQ EYQNAIKVEP VSPPYYSEKT 120

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Nucleotide Sequence
(Fasta)

ATGGGTGAAA CTCTGGGAGT TTCTCCTGTT GACCTAGGGG GTGATTCCTT CCCGGATACA 60
TTGTCTGCAA GCACTTCACA AGGTAAAGTG GGTTGCAGAG GTTGCTCTGG GGGGTGCTCT 120

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Sequence Source

Ensembl

Keyword

KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0675--Receptor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003074--1Cnucl_rcpt
IPR003076--1Cnucl_rcpt_A
IPR000536--Nucl_hrmn_rcpt_lig-bd
IPR001723--Nuclear_hrmn_rcpt
IPR001628--Znf_hrmn_rcpt
IPR013088--Znf_NHR/GATA

PROSITE

PS00031--NUCLEAR_REC_DBD_1
PS51030--NUCLEAR_REC_DBD_2

Pfam

PF00104--Hormone_recep
PF00105--zf-C4

PRINTS

PR01288--PROXISOMEPAR
PR01289--PROXISOMPAAR
PR00398--STRDHORMONER
PR00047--STROIDFINGER

SMART

SM00430--HOLI
SM00399--ZnF_C4

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0008144--F:drug binding
GO:0008289--F:lipid binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0004879--F:RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
GO:0003707--F:steroid hormone receptor activity
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001190--F:transcriptional activator activity, RNA polymerase II transcription factor binding
GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0008270--F:zinc ion binding
GO:0032922--P:circadian regulation of gene expression
GO:0070166--P:enamel mineralization
GO:0008544--P:epidermis development
GO:0006631--P:fatty acid metabolic process
GO:0032099--P:negative regulation of appetite
GO:0010887--P:negative regulation of cholesterol storage
GO:0050728--P:negative regulation of inflammatory response
GO:1903038--P:negative regulation of leukocyte cell-cell adhesion
GO:0010745--P:negative regulation of macrophage derived foam cell differentiation
GO:1902894--P:negative regulation of pri-miRNA transcription from RNA polymerase II promoter
GO:0010871--P:negative regulation of receptor biosynthetic process
GO:0010891--P:negative regulation of sequestering of triglyceride
GO:0046321--P:positive regulation of fatty acid oxidation
GO:0045722--P:positive regulation of gluconeogenesis
GO:0072366--P:regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter
GO:0042752--P:regulation of circadian rhythm
GO:0072363--P:regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter
GO:0072369--P:regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter
GO:0042060--P:wound healing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001214	Ailuropoda melanoleuca	74.06	0.00e+00	692.00
IUUC-Aca-005129	Anolis carolinensis	67.48	7.00e-177	612.00
IUUC-Bta-013226	Bos taurus	74.46	0.00e+00	703.00
IUUC-Cja-019236	Callithrix jacchus	75.64	0.00e+00	715.00
IUUC-Cfa-020281	Canis familiaris	76.44	0.00e+00	721.00
IUUC-Cpo-021587	Cavia porcellus	74.48	0.00e+00	668.00
IUUC-Csa-023400	Chlorocebus sabaeus	76.42	0.00e+00	679.00
IUUC-Cho-024593	Choloepus hoffmanni	76.83	0.00e+00	652.00
IUUC-Dno-029063	Dasypus novemcinctus	74.95	0.00e+00	673.00
IUUC-Ete-032520	Echinops telfairi	73.86	0.00e+00	684.00
IUUC-Fca-035935	Felis catus	76.04	0.00e+00	718.00
IUUC-Fal-037524	Ficedula albicollis	69.89	3.00e-178	617.00
IUUC-Gga-041223	Gallus gallus	70.53	1.00e-179	621.00
IUUC-Ggo-045265	Gorilla gorilla	76.04	0.00e+00	718.00
IUUC-Hsa-046916	Homo sapiens	75.64	0.00e+00	715.00
IUUC-Lch-049759	Latimeria chalumnae	60.71	2.00e-124	438.00
IUUC-Laf-054483	Loxodonta africana	73.66	0.00e+00	692.00
IUUC-Meu-056587	Macropus eugenii	73.00	0.00e+00	648.00
IUUC-Mga-059530	Meleagris gallopavo	70.53	1.00e-179	621.00
IUUC-Mmr-060576	Microcebus murinus	74.26	0.00e+00	702.00
IUUC-Mdo-061854	Monodelphis domestica	75.58	0.00e+00	666.00
IUUC-Mmu-063724	Mus musculus	74.85	0.00e+00	708.00
IUUC-Mpu-066888	Mustela putorius furo	76.21	0.00e+00	710.00
IUUC-Mlu-067978	Myotis lucifugus	75.64	0.00e+00	747.00
IUUC-Nle-070069	Nomascus leucogenys	76.04	0.00e+00	719.00
IUUC-Opr-070630	Ochotona princeps	73.98	2.00e-155	541.00
IUUC-Ocu-074862	Oryctolagus cuniculus	75.47	0.00e+00	674.00
IUUC-Oga-089143	Otolemur garnettii	74.65	0.00e+00	710.00
IUUC-Oar-089725	Ovis aries	74.85	0.00e+00	705.00
IUUC-Ptr-091580	Pan troglodytes	75.84	0.00e+00	717.00
IUUC-Psi-093041	Pelodiscus sinensis	68.55	3.00e-173	600.00
IUUC-Pab-098333	Pongo abelii	75.47	0.00e+00	668.00
IUUC-Pca-100861	Procavia capensis	74.42	0.00e+00	663.00
IUUC-Pva-102186	Pteropus vampyrus	84.75	0.00e+00	719.00
IUUC-Rno-105583	Rattus norvegicus	74.85	0.00e+00	707.00
IUUC-Sha-107484	Sarcophilus harrisii	74.08	0.00e+00	670.00
IUUC-Sar-112996	Sorex araneus	85.04	9.00e-149	519.00
IUUC-Ssc-115945	Sus scrofa	76.04	0.00e+00	714.00
IUUC-Tsy-119098	Tarsius syrichta	84.95	0.00e+00	712.00
IUUC-Ttr-129292	Tursiops truncatus	76.04	0.00e+00	718.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence