iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
FBgn0058045	FBtr0331585	FBpp0303975
FBgn0058045	FBtr0111163	FBpp0110481
FBgn0058045	FBtr0331586	FBpp0303976

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
PINA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.90e-50	169.2	10	157

Active Site

Position(s)	Description	Evidence
90	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 2    lkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk...........e 88
           lkk+l+el+k+p+eg+sa++ de+d+++wevli+Gp+dt Yegg+Fk++++fp++YP++PP++kf+t+i+hPn+++nG+vC+sil+            
   Q: 10   LKKQLAELNKNPVEGFSAGLIDENDIFRWEVLIIGPPDTLYEGGFFKAHLYFPKEYPLRPPRMKFVTEIWHPNIEKNGDVCISILHepgddkwgyekA 107
           7899*********************************************************************************8888899999999 PP
   S: 89   eekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           +e+W p+++ve++l+s++s+la+pn esp+n++aa++++++ +++k+kv 
   Q: 108  SERWLPVHTVETILISVISMLADPNDESPANVDAAKEWRESYTDFKRKVA 157
           9**********************************************985 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MSELQSSLLL KKQLAELNKN PVEGFSAGLI DENDIFRWEV LIIGPPDTLY EGGFFKAHLY 60
FPKEYPLRPP RMKFVTEIWH PNIEKNGDVC ISILHEPGDD KWGYEKASER WLPVHTVETI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATAACTAGTT CTTTTTTATG TTTGGCCTTT ATAGAAAATT CGGTGGTCGA TGTCGATCAT 60
TATATTTACT TTCAATACTA ACTTATTTTT AAGCATACAA TTTTTATTTG TGTTAATTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0000209--P:protein polyubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

dme:Dmel_CG40045

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000411	Aegilops tauschii	47.46	3.00e-44	170.00
IUUC-Aml-001379	Ailuropoda melanoleuca	82.61	1.00e-78	284.00
IUUC-Atr-003150	Amborella trichopoda	68.00	2.00e-49	187.00
IUUC-Apl-003579	Anas platyrhynchos	80.61	8.00e-79	285.00
IUUC-Aca-005146	Anolis carolinensis	84.21	6.00e-76	275.00
IUUC-Aly-005673	Arabidopsis lyrata	69.18	1.00e-54	204.00
IUUC-Ath-007644	Arabidopsis thaliana	69.18	1.00e-54	204.00
IUUC-Afl-008660	Aspergillus flavus	56.55	2.00e-51	193.00
IUUC-Ang-009536	Aspergillus niger	55.36	4.00e-50	189.00
IUUC-Aor-009951	Aspergillus oryzae	56.97	3.00e-51	193.00
IUUC-Ame-010634	Astyanax mexicanus	84.62	1.00e-67	251.00
IUUC-Bta-013324	Bos taurus	84.56	8.00e-75	271.00
IUUC-Bdi-014844	Brachypodium distachyon	63.70	2.00e-51	193.00
IUUC-Bol-016017	Brassica oleracea	66.67	3.00e-62	229.00
IUUC-Bra-017324	Brassica rapa	67.33	4.00e-56	209.00
IUUC-Cja-018734	Callithrix jacchus	79.75	1.00e-76	277.00
IUUC-Cfa-020846	Canis familiaris	81.33	6.00e-80	288.00
IUUC-Cpo-022207	Cavia porcellus	84.31	2.00e-76	276.00
IUUC-Cre-022895	Chlamydomonas reinhardtii	66.06	1.00e-60	224.00
IUUC-Csa-024193	Chlorocebus sabaeus	84.56	8.00e-75	271.00
IUUC-Cho-024621	Choloepus hoffmanni	50.33	3.00e-34	137.00
IUUC-Csv-026074	Ciona savignyi	75.00	6.00e-70	254.00
IUUC-Cme-027321	Cyanidioschyzon merolae	63.41	1.00e-54	204.00
IUUC-Dre-028653	Danio rerio	83.13	2.00e-82	296.00
IUUC-Dno-029479	Dasypus novemcinctus	84.56	8.00e-75	271.00
IUUC-Ete-032885	Echinops telfairi	84.56	1.00e-74	271.00
IUUC-Eca-034057	Equus caballus	84.21	8.00e-76	274.00
IUUC-Eeu-035128	Erinaceus europaeus	66.00	4.00e-51	192.00
IUUC-Fca-035835	Felis catus	84.21	7.00e-76	275.00
IUUC-Fal-036778	Ficedula albicollis	84.56	8.00e-75	271.00
IUUC-Gmo-039029	Gadus morhua	81.55	7.00e-79	285.00
IUUC-Gga-040950	Gallus gallus	84.56	8.00e-75	271.00
IUUC-Gac-042438	Gasterosteus aculeatus	81.46	8.00e-72	261.00
IUUC-Gma-044131	Glycine max	70.00	2.00e-50	190.00
IUUC-Ggo-044826	Gorilla gorilla	84.56	8.00e-75	271.00
IUUC-Hsa-046638	Homo sapiens	84.56	8.00e-75	271.00
IUUC-Hvu-047065	Hordeum vulgare	62.67	3.00e-52	197.00
IUUC-Itr-048581	Ictidomys tridecemlineatus	82.76	1.00e-55	206.00
IUUC-Lch-050446	Latimeria chalumnae	83.13	4.00e-82	295.00
IUUC-Lpe-050981	Leersia perrieri	65.07	1.00e-52	197.00
IUUC-Loc-052277	Lepisosteus oculatus	84.56	8.00e-75	271.00
IUUC-Lma-053320	Leptosphaeria maculans	58.49	4.00e-51	192.00
IUUC-Laf-053491	Loxodonta africana	84.56	8.00e-75	271.00
IUUC-Mcc-055624	Macaca mulatta	79.27	3.00e-75	273.00
IUUC-Meu-056870	Macropus eugenii	83.33	1.00e-69	254.00
IUUC-Mtr-058646	Medicago truncatula	70.00	7.00e-56	208.00
IUUC-Mla-059165	Melampsora laricipopulina	58.58	1.00e-60	224.00
IUUC-Mga-060005	Meleagris gallopavo	84.77	1.00e-75	274.00
IUUC-Mvi-060318	Microbotryum violaceum	63.58	1.00e-54	204.00
IUUC-Mmr-061442	Microcebus murinus	84.56	8.00e-75	271.00
IUUC-Mdo-062364	Monodelphis domestica	82.53	1.00e-81	294.00
IUUC-Mmu-064163	Mus musculus	84.56	8.00e-75	271.00
IUUC-Mac-065294	Musa acuminata	65.33	3.00e-54	202.00
IUUC-Mpu-066561	Mustela putorius furo	80.12	3.00e-78	282.00
IUUC-Mlu-067444	Myotis lucifugus	78.79	5.00e-78	281.00
IUUC-Opr-070958	Ochotona princeps	84.67	3.00e-75	272.00
IUUC-Ont-071843	Oreochromis niloticus	81.33	1.00e-80	290.00
IUUC-Ocu-074321	Oryctolagus cuniculus	80.49	6.00e-77	278.00
IUUC-Oba-075915	Oryza barthii	65.75	2.00e-58	216.00
IUUC-Obr-076863	Oryza brachyantha	65.75	1.00e-53	201.00
IUUC-Ogl-076981	Oryza glaberrima	65.75	2.00e-58	216.00
IUUC-Ogu-078183	Oryza glumaepatula	65.75	2.00e-58	216.00
IUUC-Oin-079755	Oryza indica	65.75	2.00e-58	216.00
IUUC-Olo-080576	Oryza longistaminata	65.75	2.00e-58	216.00
IUUC-Ome-081190	Oryza meridionalis	62.58	9.00e-57	211.00
IUUC-Oni-083010	Oryza nivara	65.75	2.00e-58	216.00
IUUC-Opu-083784	Oryza punctata	65.07	2.00e-52	197.00
IUUC-Oru-084817	Oryza rufipogon	65.75	2.00e-58	216.00
IUUC-Osa-085291	Oryza sativa	65.75	2.00e-58	216.00
IUUC-Ola-087259	Oryzias latipes	82.55	3.00e-73	266.00
IUUC-Olu-087887	Ostreococcus lucimarinus	67.90	3.00e-68	249.00
IUUC-Oga-088473	Otolemur garnettii	81.99	1.00e-78	283.00
IUUC-Oar-090047	Ovis aries	84.77	1.00e-75	274.00
IUUC-Ptr-091331	Pan troglodytes	84.67	3.00e-75	272.00
IUUC-Pan-092230	Papio anubis	84.56	8.00e-75	271.00
IUUC-Psi-093996	Pelodiscus sinensis	84.77	9.00e-76	274.00
IUUC-Ppa-095611	Physcomitrella patens	66.67	1.00e-65	241.00
IUUC-Pfo-096159	Poecilia formosa	81.93	3.00e-81	292.00
IUUC-Pab-098727	Pongo abelii	84.56	8.00e-75	271.00
IUUC-Pop-099881	Populus trichocarpa	69.09	8.00e-64	234.00
IUUC-Pca-100369	Procavia capensis	83.56	4.00e-71	259.00
IUUC-Ppe-101778	Prunus persica	70.00	2.00e-56	210.00
IUUC-Pva-103074	Pteropus vampyrus	84.56	4.00e-75	273.00
IUUC-Pgr-103274	Puccinia graminis	59.69	6.00e-49	185.00
IUUC-Rno-104929	Rattus norvegicus	84.56	8.00e-75	271.00
IUUC-Sha-106753	Sarcophilus harrisii	82.53	1.00e-81	294.00
IUUC-Sja-107917	Schizosaccharomyces japonicus	71.43	3.00e-50	189.00
IUUC-Spo-108104	Schizosaccharomyces pombe	68.48	2.00e-66	243.00
IUUC-Smo-109401	Selaginella moellendorffii	65.66	2.00e-52	197.00
IUUC-Sit-110784	Setaria italica	64.38	4.00e-52	196.00
IUUC-Sly-111843	Solanum lycopersicum	64.63	3.00e-58	216.00
IUUC-Stu-112654	Solanum tuberosum	67.59	4.00e-54	202.00
IUUC-Sbi-113787	Sorghum bicolor	65.22	3.00e-58	216.00
IUUC-Sre-114933	Sporisorium reilianum	62.80	2.00e-57	213.00
IUUC-Ssc-115912	Sus scrofa	80.12	1.00e-77	281.00
IUUC-Tgu-116635	Taeniopygia guttata	84.77	1.00e-75	274.00
IUUC-Tru-117873	Takifugu rubripes	77.84	1.00e-78	283.00
IUUC-Tsy-119168	Tarsius syrichta	83.44	3.00e-75	273.00
IUUC-Tni-119853	Tetraodon nigroviridis	77.38	3.00e-77	279.00
IUUC-Tca-121649	Theobroma cacao	65.99	1.00e-54	204.00
IUUC-Tae-125278	Triticum aestivum	63.33	1.00e-52	197.00
IUUC-Tur-126873	Triticum urartu	63.58	3.00e-54	204.00
IUUC-Tbe-127917	Tupaia belangeri	84.67	3.00e-75	272.00
IUUC-Ttr-128609	Tursiops truncatus	84.56	2.00e-74	271.00
IUUC-Uma-129506	Ustilago maydis	63.41	5.00e-58	216.00
IUUC-Vpa-130208	Vicugna pacos	84.67	1.00e-75	275.00
IUUC-Vvi-131387	Vitis vinifera	66.67	2.00e-54	203.00
IUUC-Xtr-131942	Xenopus tropicalis	83.89	2.00e-74	270.00
IUUC-Xma-134050	Xiphophorus maculatus	81.93	3.00e-81	292.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence