iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSG00000133316.15	ENST00000536401.1	ENSP00000439541.1
ENSG00000133316.15	ENST00000311713.11	ENSP00000308931.7
ENSG00000133316.15	ENST00000529106.5	ENSP00000435726.1
ENSG00000133316.15	ENST00000542347.5	ENSP00000438700.1

Annotation

Cancer Mutation
TCGA	ICGC	COSMIC	CGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	TCGA	ICGC
COSMIC	THPA	HPM
DNA & RNA Element
UTRdb	circBase	CircNet	miRTarBase
microRNA	TRANSFAC	RepTar	SomamiR
miRcode	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	HINT
Mentha	InWeb_IM
Post-translational Modifications (PTMs)
CPLM	dbPAF	PhosphositePlus	dbPTM
HPRD	Phospho.ELM	UniProt	PHOSIDA
BioGRID	mUbiSiDa
DNA Methylation
TCGA	ICGC
Protein Expression/Proteomics
THPA	HPM	GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.70e-10	41.8	269	297

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 3    tdsvtclaf.sd.tllvsGsdDgtikvWD 29
           ++sv++l+  ++ +ll+s++ D ++++ +
   Q: 269  AGSVRGLQChPSkPLLASCGLDRVLRIHR 297
           5789**9999778************9965 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MAAAAARWNH VWVGTETGIL KGVNLQRKQA ANFTAGGQPR REEAVSALCW GTGGETQMLV 60
GCADRTVKHF STEDGIFQGQ RHCPGGEGMF RGLAQADGTL ITCVDSGILR VWHDKDKDTS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCGCTTCTC GGCCTTTTGG CTAAGATCAA GTGTAGTATC TGTTCTTATC AGTTTAATAT 60
CTGATACGTC CTCTATCCGA GGACAATATA TTAAATGGAT TTTTGGAAAT AGGAGATGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0488--Methylation
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0030687--C:preribosome, large subunit precursor
GO:0042273--P:ribosomal large subunit biogenesis

KEGG

hsa:54663

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000787	Aegilops tauschii	32.56	6.00e-25	108.00
IUUC-Aml-001460	Ailuropoda melanoleuca	89.92	0.00e+00	717.00
IUUC-Atr-002657	Amborella trichopoda	36.21	4.00e-25	109.00
IUUC-Aly-006380	Arabidopsis lyrata	34.89	6.00e-28	118.00
IUUC-Ath-007686	Arabidopsis thaliana	39.08	3.00e-26	113.00
IUUC-Ame-011942	Astyanax mexicanus	55.97	1.00e-111	396.00
IUUC-Bta-013382	Bos taurus	92.19	0.00e+00	729.00
IUUC-Bdi-014280	Brachypodium distachyon	35.10	2.00e-29	123.00
IUUC-Bra-017855	Brassica rapa	40.23	5.00e-28	119.00
IUUC-Cja-018933	Callithrix jacchus	95.58	0.00e+00	738.00
IUUC-Cfa-020634	Canis familiaris	90.34	0.00e+00	710.00
IUUC-Cpo-022089	Cavia porcellus	83.55	3.00e-177	614.00
IUUC-Csa-023835	Chlorocebus sabaeus	97.14	0.00e+00	771.00
IUUC-Cho-024385	Choloepus hoffmanni	69.30	8.00e-87	313.00
IUUC-Cin-025691	Ciona intestinalis	43.53	2.00e-74	272.00
IUUC-Dre-028473	Danio rerio	54.75	1.00e-104	373.00
IUUC-Dno-029687	Dasypus novemcinctus	90.26	0.00e+00	704.00
IUUC-Dor-030529	Dipodomys ordii	89.54	4.00e-128	451.00
IUUC-Dme-031982	Drosophila melanogaster	30.72	3.00e-35	142.00
IUUC-Ete-032407	Echinops telfairi	60.88	4.00e-107	381.00
IUUC-Eca-033792	Equus caballus	84.75	2.00e-176	611.00
IUUC-Fca-036584	Felis catus	90.62	0.00e+00	724.00
IUUC-Gmo-039064	Gadus morhua	58.23	3.00e-104	371.00
IUUC-Gac-042170	Gasterosteus aculeatus	54.01	1.00e-100	360.00
IUUC-Gma-044150	Glycine max	31.47	1.00e-26	114.00
IUUC-Ggo-044955	Gorilla gorilla	98.70	0.00e+00	781.00
IUUC-Hvu-047119	Hordeum vulgare	33.86	1.00e-28	120.00
IUUC-Itr-048987	Ictidomys tridecemlineatus	90.13	0.00e+00	704.00
IUUC-Kpa-049188	Komagataella pastoris	29.51	4.00e-19	89.00
IUUC-Lch-050396	Latimeria chalumnae	58.11	1.00e-122	432.00
IUUC-Laf-054015	Loxodonta africana	89.12	0.00e+00	680.00
IUUC-Mcc-055589	Macaca mulatta	97.66	0.00e+00	775.00
IUUC-Meu-056160	Macropus eugenii	61.67	1.00e-119	423.00
IUUC-Mtr-057719	Medicago truncatula	32.63	9.00e-28	118.00
IUUC-Mmr-060801	Microcebus murinus	91.95	0.00e+00	741.00
IUUC-Mdo-062069	Monodelphis domestica	72.77	2.00e-153	535.00
IUUC-Mmu-063586	Mus musculus	89.35	0.00e+00	675.00
IUUC-Mpu-066542	Mustela putorius furo	91.43	0.00e+00	711.00
IUUC-Mlu-067520	Myotis lucifugus	76.35	7.00e-155	540.00
IUUC-Nle-069422	Nomascus leucogenys	97.14	0.00e+00	769.00
IUUC-Opr-070402	Ochotona princeps	75.44	2.00e-94	338.00
IUUC-Ont-072078	Oreochromis niloticus	60.00	4.00e-108	384.00
IUUC-Ocu-073886	Oryctolagus cuniculus	88.95	0.00e+00	674.00
IUUC-Obr-076206	Oryza brachyantha	33.33	6.00e-32	132.00
IUUC-Ogl-077112	Oryza glaberrima	34.24	1.00e-31	130.00
IUUC-Ogu-078172	Oryza glumaepatula	36.23	3.00e-27	116.00
IUUC-Oin-080070	Oryza indica	34.24	2.00e-31	130.00
IUUC-Olo-080534	Oryza longistaminata	31.93	6.00e-29	122.00
IUUC-Ome-081869	Oryza meridionalis	31.93	1.00e-28	120.00
IUUC-Opu-083828	Oryza punctata	33.59	2.00e-29	123.00
IUUC-Oru-084690	Oryza rufipogon	32.96	4.00e-29	122.00
IUUC-Ola-087342	Oryzias latipes	55.41	3.00e-94	338.00
IUUC-Oga-088865	Otolemur garnettii	91.32	0.00e+00	715.00
IUUC-Oar-090030	Ovis aries	91.41	0.00e+00	722.00
IUUC-Pan-092461	Papio anubis	97.66	0.00e+00	773.00
IUUC-Psi-093061	Pelodiscus sinensis	59.84	5.00e-132	464.00
IUUC-Pma-094281	Petromyzon marinus	53.28	9.00e-102	363.00
IUUC-Ppa-095623	Physcomitrella patens	35.37	3.00e-30	126.00
IUUC-Pfo-097074	Poecilia formosa	58.44	7.00e-97	347.00
IUUC-Pab-098290	Pongo abelii	98.96	0.00e+00	781.00
IUUC-Pop-099317	Populus trichocarpa	38.51	8.00e-26	111.00
IUUC-Pca-100383	Procavia capensis	87.01	0.00e+00	655.00
IUUC-Ppe-101867	Prunus persica	35.29	3.00e-26	113.00
IUUC-Pva-103218	Pteropus vampyrus	77.40	2.00e-170	591.00
IUUC-Rno-105494	Rattus norvegicus	89.90	0.00e+00	709.00
IUUC-Sha-107127	Sarcophilus harrisii	72.15	4.00e-155	541.00
IUUC-Sit-110466	Setaria italica	38.30	1.00e-27	117.00
IUUC-Sbi-113854	Sorghum bicolor	39.25	7.00e-28	118.00
IUUC-Ssc-116144	Sus scrofa	90.89	0.00e+00	691.00
IUUC-Tru-118516	Takifugu rubripes	51.43	5.00e-105	374.00
IUUC-Tni-120527	Tetraodon nigroviridis	57.41	1.00e-103	369.00
IUUC-Tae-123391	Triticum aestivum	33.47	3.00e-28	120.00
IUUC-Tur-126054	Triticum urartu	32.81	1.00e-27	118.00
IUUC-Tbe-127232	Tupaia belangeri	71.43	2.00e-143	501.00
IUUC-Ttr-128529	Tursiops truncatus	92.19	0.00e+00	732.00
IUUC-Vpa-130703	Vicugna pacos	92.70	1.00e-93	336.00
IUUC-Vvi-131680	Vitis vinifera	36.84	2.00e-27	116.00
IUUC-Xtr-132802	Xenopus tropicalis	47.26	3.00e-93	335.00
IUUC-Xma-133396	Xiphophorus maculatus	50.47	2.00e-79	289.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence