iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004261

UUCD1 version

UUC-AnC-00984

Ensembl Protein ID

ENSACAP00000001315.3

UniProt Accession

G1K9E3; G1K9E3_ANOCA

Protein Name

Uncharacterized protein

Gene Name

USP15

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000000802.3	ENSACAT00000001348.3	ENSACAP00000001315.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.20e-120	401.3	348	992
ULD/UDP/UBQ/UBQ_Other	1.90e-09	37.2	207	277

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           +Gl+NlgNtC+mNS++QcLsn+p+l+e++l+ k++e+ln +np ++ ge++ks+++l++++w++k ++v+pr+++++++++a++fsgy+
   Q: 348  CGLSNLGNTCFMNSAIQCLSNTPPLTEYFLNdKYQEELNFDNPLGMRGEIAKSYAELIKQMWSGKYSYVTPRAFKTQVGRFAPQFSGYQ 436
           7******************************9********************************************************* PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           qqD+qE+laflld+l+e+l++ ++kp+ +++++d   ++d+     a+e++ k+n+s+i+d+F+g +ks+++c+ec+++s++++pf++l
   Q: 437  QQDCQELLAFLLDGLHEDLNRIRKKPYIQLKDAD--GRPDKvvaeeAWENHLKRNDSIIVDIFHGLFKSTLVCPECAKISVTFDPFCYL 523
           ******************************9999..5555555777******************************************* PP
   S: 173  slpvpgkeetkke............................................................................ 185
           +lp+p+k+e+++e                                                                            
   Q: 524  TLPLPMKKERSLEvylvrmdplakpmqykvvvpkigniqdlctalstlsgvaadkmivtdiynhrfhrifamdenlssimerddiyvfe 612
           **********999**************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 613  iginrtedteqvvipvclrekfrhsgyshhsgsthfgqpfliavprnntedklynllllrmcryvktssetedteaslqcckdngingn 701
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 702  gpngiheegspsemetdeqddessqdqelpsenensqsedsvggdndsenglctedsckdqlighkkrlftfqfnslgntdinyvkddt 790
           ***************************************************************************************** PP
   S: 186  .......................................................slqdcLesftkeeelegenkyycekckkkqeaek 219
                                                                  +l+dc+e ft++e+l  e+ +yc++ck++q+a+k
   Q: 791  rhirfddrqlrldersflaldwdpeykkrffdenaaedfekhesveyrppkkpfvKLKDCIELFTTKEKLGAEDPWYCPNCKEHQQATK 879
           ***************************************************************************************** PP
   S: 220  klklkklPevLilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.W 306
           kl+l++lP+vL++hLkRfs+s+  ++r k+++ vefp++ Ld+s+f+++p+ +   +++Y+Liav +H+G++++GHY+a++kn++++ W
   Q: 880  KLDLWSLPPVLVVHLKRFSYSR--YMRDKLDTLVEFPITdLDMSEFLINPNAG---PCRYNLIAVSNHYGGMGGGHYTAFAKNKDDGkW 963
           ******************9977..6999*********************9988...8**************************65555* PP
   S: 307  llfdDskVtevkeeevleetgstaYvlfYkrr 338
           ++fdDs+V++ +ee++++   + aYvlfY+r+
   Q: 964  YYFDDSSVSTASEEQIVS---KAAYVLFYQRQ 992
           ******************...*********96 PP

ULD/UDP/UBQ/UBQ_Other

   S: 12   eltlkvnpsdtVaeLKekiekklgip.peqqrLiyk.....GkiL.eddktLadyglkdgstihllekksg 75
           + t++++++dt+ ++ ++i+k ++ip + + rL++k      ++L ++d t++d gl++g+++++++++++
   Q: 207  VVTRRFSKADTIDTIEKEIRKIFNIPdEKETRLWNKymsntFEPLnKPDSTIQDAGLYQGQVLVIEQRNED 277
           77899*********************999*****998875544569*********************9986 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MGLPKWEGVV EGVSPVAARR HSQHAARPAP AAAAAPVTAA ASSSAAVTFA AAAGAAGLGD 60
MAEGGAADLE TQRSDITALL KTALRKGDTW YLVDSRWFKQ WKKYVGFDSW DKYQMGDQNV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATACCTGCC ATAGATGCAG GCGAAACGTC AGGAAAGAAT GCTTCTGGAA CAGGACCATA 60
CAGCCCGGAA AACTCACAGT AACCCAGAAT ATATATTGTA GTAGTCTACT TTGTAGAATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR029071--Ubiquitin-rel_dom
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH
PF14533--USP7_C2

SMART

SM00695--DUSP

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0030509--P:BMP signaling pathway
GO:0035616--P:histone H2B conserved C-terminal lysine deubiquitination
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0060389--P:pathway-restricted SMAD protein phosphorylation
GO:0007179--P:transforming growth factor beta receptor signaling pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

acs:100554748

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000425	Aegilops tauschii	38.83	6.00e-105	375.00
IUUC-Aml-001852	Ailuropoda melanoleuca	92.88	0.00e+00	1791.00
IUUC-Apl-003249	Anas platyrhynchos	95.48	0.00e+00	1716.00
IUUC-Acl-008284	Aspergillus clavatus	37.96	3.00e-55	210.00
IUUC-Afl-008507	Aspergillus flavus	43.30	1.00e-54	208.00
IUUC-Afu-008878	Aspergillus fumigatus	38.26	4.00e-55	210.00
IUUC-Ani-009479	Aspergillus nidulans	43.25	1.00e-52	202.00
IUUC-Ang-009562	Aspergillus niger	42.48	4.00e-55	210.00
IUUC-Aor-009949	Aspergillus oryzae	42.96	1.00e-53	204.00
IUUC-Ate-010323	Aspergillus terreus	37.56	1.00e-55	212.00
IUUC-Ame-010757	Astyanax mexicanus	77.80	0.00e+00	1239.00
IUUC-Bta-013128	Bos taurus	91.54	0.00e+00	1766.00
IUUC-Bci-013993	Botrytis cinerea	36.84	2.00e-63	238.00
IUUC-Bdi-014013	Brachypodium distachyon	35.68	1.00e-148	520.00
IUUC-Cel-018203	Caenorhabditis elegans	58.91	2.00e-69	257.00
IUUC-Cja-019222	Callithrix jacchus	93.08	0.00e+00	1795.00
IUUC-Cfa-020035	Canis familiaris	92.88	0.00e+00	1790.00
IUUC-Cpo-022071	Cavia porcellus	93.27	0.00e+00	1720.00
IUUC-Csa-023882	Chlorocebus sabaeus	93.38	0.00e+00	1801.00
IUUC-Cho-024875	Choloepus hoffmanni	96.27	9.00e-140	491.00
IUUC-Cin-025292	Ciona intestinalis	44.44	0.00e+00	746.00
IUUC-Csv-026109	Ciona savignyi	43.22	0.00e+00	686.00
IUUC-Cgl-026741	Colletotrichum gloeosporioides	40.07	1.00e-60	229.00
IUUC-Cne-026852	Cryptococcus neoformans	46.62	4.00e-72	266.00
IUUC-Cme-027338	Cyanidioschyzon merolae	56.05	2.00e-68	253.00
IUUC-Dre-027869	Danio rerio	64.75	0.00e+00	813.00
IUUC-Dno-029025	Dasypus novemcinctus	89.14	0.00e+00	1716.00
IUUC-Dor-030956	Dipodomys ordii	84.73	0.00e+00	1535.00
IUUC-Dse-031432	Dothistroma septosporum	40.43	4.00e-59	223.00
IUUC-Eca-034340	Equus caballus	93.80	0.00e+00	1747.00
IUUC-Eeu-034488	Erinaceus europaeus	83.65	0.00e+00	1189.00
IUUC-Fca-035552	Felis catus	91.44	0.00e+00	1758.00
IUUC-Fal-036618	Ficedula albicollis	95.38	0.00e+00	1709.00
IUUC-Gmo-038680	Gadus morhua	64.41	0.00e+00	811.00
IUUC-Ggr-039740	Gaeumannomyces graminis	42.86	5.00e-61	230.00
IUUC-Gga-041146	Gallus gallus	94.50	0.00e+00	1758.00
IUUC-Gac-041679	Gasterosteus aculeatus	77.47	0.00e+00	1451.00
IUUC-Gma-043077	Glycine max	36.53	3.00e-151	529.00
IUUC-Ggo-045002	Gorilla gorilla	93.39	0.00e+00	1741.00
IUUC-Hsa-046052	Homo sapiens	93.28	0.00e+00	1799.00
IUUC-Hvu-047108	Hordeum vulgare	40.09	2.00e-122	432.00
IUUC-Itr-048306	Ictidomys tridecemlineatus	91.86	0.00e+00	1769.00
IUUC-Lch-050107	Latimeria chalumnae	86.47	0.00e+00	1725.00
IUUC-Lpe-051185	Leersia perrieri	39.97	2.00e-125	443.00
IUUC-Loc-052105	Lepisosteus oculatus	83.58	0.00e+00	1498.00
IUUC-Lma-052981	Leptosphaeria maculans	36.66	4.00e-66	247.00
IUUC-Laf-053645	Loxodonta africana	92.57	0.00e+00	1790.00
IUUC-Mcc-055586	Macaca mulatta	93.28	0.00e+00	1799.00
IUUC-Meu-056764	Macropus eugenii	87.27	0.00e+00	954.00
IUUC-Mor-056985	Magnaporthe oryzae	41.76	2.00e-60	228.00
IUUC-Mpo-057486	Magnaporthe poae	42.12	3.00e-60	227.00
IUUC-Mtr-058138	Medicago truncatula	36.52	5.00e-157	548.00
IUUC-Mga-060162	Meleagris gallopavo	94.81	0.00e+00	1764.00
IUUC-Mvi-060324	Microbotryum violaceum	43.28	8.00e-74	272.00
IUUC-Mmr-061105	Microcebus murinus	93.48	0.00e+00	1801.00
IUUC-Mdo-062107	Monodelphis domestica	93.08	0.00e+00	1775.00
IUUC-Mmu-063662	Mus musculus	92.36	0.00e+00	1785.00
IUUC-Mpu-065868	Mustela putorius furo	91.12	0.00e+00	1783.00
IUUC-Mlu-068000	Myotis lucifugus	86.73	0.00e+00	1617.00
IUUC-Nfi-068330	Neosartorya fischeri	37.47	5.00e-55	210.00
IUUC-Ncr-068879	Neurospora crassa	44.89	3.00e-60	227.00
IUUC-Nle-069874	Nomascus leucogenys	93.16	0.00e+00	1778.00
IUUC-Opr-071212	Ochotona princeps	87.83	0.00e+00	1687.00
IUUC-Ont-071834	Oreochromis niloticus	78.63	0.00e+00	1434.00
IUUC-Ocu-074573	Oryctolagus cuniculus	93.48	0.00e+00	1803.00
IUUC-Oba-075553	Oryza barthii	39.10	3.00e-127	449.00
IUUC-Obr-076416	Oryza brachyantha	40.09	1.00e-119	423.00
IUUC-Ogl-077583	Oryza glaberrima	39.10	3.00e-127	449.00
IUUC-Ogu-077990	Oryza glumaepatula	38.68	4.00e-122	432.00
IUUC-Oin-079300	Oryza indica	39.25	2.00e-128	452.00
IUUC-Olo-080387	Oryza longistaminata	39.01	3.00e-120	426.00
IUUC-Oni-082303	Oryza nivara	38.83	9.00e-123	434.00
IUUC-Opu-083770	Oryza punctata	39.55	3.00e-126	446.00
IUUC-Oru-085141	Oryza rufipogon	38.91	1.00e-124	441.00
IUUC-Osa-085641	Oryza sativa	39.25	2.00e-128	452.00
IUUC-Oga-089022	Otolemur garnettii	91.44	0.00e+00	1763.00
IUUC-Oar-089767	Ovis aries	92.77	0.00e+00	1791.00
IUUC-Ptr-091319	Pan troglodytes	91.95	0.00e+00	1774.00
IUUC-Pan-091968	Papio anubis	93.38	0.00e+00	1801.00
IUUC-Psi-093849	Pelodiscus sinensis	94.54	0.00e+00	1712.00
IUUC-Pma-094533	Petromyzon marinus	59.76	0.00e+00	1106.00
IUUC-Pno-094890	Phaeosphaeria nodorum	35.14	5.00e-59	223.00
IUUC-Pfo-097110	Poecilia formosa	77.86	0.00e+00	1435.00
IUUC-Pab-098664	Pongo abelii	93.38	0.00e+00	1801.00
IUUC-Pca-100359	Procavia capensis	75.20	0.00e+00	1246.00
IUUC-Pva-102394	Pteropus vampyrus	91.65	0.00e+00	1756.00
IUUC-Pgr-103546	Puccinia graminis	30.89	1.00e-69	258.00
IUUC-Pte-104102	Pyrenophora teres	36.34	5.00e-57	217.00
IUUC-Pyt-104812	Pyrenophora triticirepentis	39.87	2.00e-56	214.00
IUUC-Rno-105383	Rattus norvegicus	91.54	0.00e+00	1767.00
IUUC-Sha-107393	Sarcophilus harrisii	93.18	0.00e+00	1781.00
IUUC-Sja-107752	Schizosaccharomyces japonicus	35.57	2.00e-80	294.00
IUUC-Ssl-108461	Sclerotinia sclerotiorum	31.11	4.00e-14	73.20
IUUC-Sit-109948	Setaria italica	36.05	6.00e-139	488.00
IUUC-Sly-111726	Solanum lycopersicum	39.19	1.00e-93	337.00
IUUC-Sar-113498	Sorex araneus	93.08	0.00e+00	1795.00
IUUC-Sbi-114874	Sorghum bicolor	35.49	2.00e-139	490.00
IUUC-Sre-115130	Sporisorium reilianum	43.30	6.00e-77	283.00
IUUC-Ssc-115285	Sus scrofa	93.18	0.00e+00	1793.00
IUUC-Tgu-116529	Taeniopygia guttata	95.11	0.00e+00	1770.00
IUUC-Tru-118298	Takifugu rubripes	77.09	0.00e+00	1464.00
IUUC-Tsy-119117	Tarsius syrichta	84.93	0.00e+00	1078.00
IUUC-Tni-120093	Tetraodon nigroviridis	74.97	0.00e+00	1380.00
IUUC-Tae-125811	Triticum aestivum	40.86	7.00e-126	444.00
IUUC-Tur-126149	Triticum urartu	38.77	5.00e-105	375.00
IUUC-Tbe-127672	Tupaia belangeri	85.41	0.00e+00	1172.00
IUUC-Ttr-128441	Tursiops truncatus	88.60	0.00e+00	1116.00
IUUC-Uma-129498	Ustilago maydis	38.29	3.00e-70	260.00
IUUC-Vda-129781	Verticillium dahliae	43.17	4.00e-65	243.00
IUUC-Vpa-130469	Vicugna pacos	92.96	0.00e+00	1727.00
IUUC-Vvi-131010	Vitis vinifera	37.74	8.00e-148	517.00
IUUC-Xtr-132729	Xenopus tropicalis	83.01	0.00e+00	1599.00
IUUC-Xma-133550	Xiphophorus maculatus	77.86	0.00e+00	1432.00
IUUC-Yli-134392	Yarrowia lipolytica	38.74	3.00e-63	237.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence