iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088220

Ensembl Protein ID

ENSOGAP00000000766.2

UniProt Accession

H0WHC7; H0WHC7_OTOGA

Genbank Protein ID

ENSOGAP00000000766

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03141474

Gene Name

SIK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000000860.2	ENSOGAT00000000861.2	ENSOGAP00000000766.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	84.06	0.00e+00	1152.00	IUUC-Hsa-046775

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MVIMSEFSAA PAGSGQGPQK PLRVGFYDVE RTLGKGNFAV VKLARHRVTK TQVAIKIIDK 60
TRLDSSNLEK IYREVQLMKL LNHPHIIKLY QVMETKDMLY IVTEFAKNGE MFDYLTSNGH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGATCA TGTCGGAGTT CAGTGCGGCC CCCGCGGGCT CGGGTCAGGG CCCGCAGAAG 60
CCCCTCCGGG TGGGCTTTTA CGACGTGGAG CGGACCCTGG GCAAAGGCAA TTTCGCTGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR034672--SIK
IPR015940--UBA

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0043276--P:anoikis
GO:0055007--P:cardiac muscle cell differentiation
GO:0043153--P:entrainment of circadian clock by photoperiod
GO:0035556--P:intracellular signal transduction
GO:0032792--P:negative regulation of CREB transcription factor activity
GO:0045721--P:negative regulation of gluconeogenesis
GO:0010868--P:negative regulation of triglyceride biosynthetic process
GO:0007346--P:regulation of mitotic cell cycle
GO:0010830--P:regulation of myotube differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001538	Ailuropoda melanoleuca	46.62	2.00e-122	432.00
IUUC-Aca-004739	Anolis carolinensis	66.87	0.00e+00	947.00
IUUC-Ame-011603	Astyanax mexicanus	64.03	0.00e+00	745.00
IUUC-Cja-019873	Callithrix jacchus	83.12	0.00e+00	1159.00
IUUC-Cfa-020801	Canis familiaris	78.26	0.00e+00	1002.00
IUUC-Cpo-022296	Cavia porcellus	76.46	0.00e+00	996.00
IUUC-Csa-023676	Chlorocebus sabaeus	82.82	0.00e+00	1144.00
IUUC-Cho-025021	Choloepus hoffmanni	75.06	5.00e-157	548.00
IUUC-Cin-025762	Ciona intestinalis	61.89	8.00e-125	441.00
IUUC-Csv-026013	Ciona savignyi	57.27	3.00e-120	424.00
IUUC-Dre-028021	Danio rerio	58.47	0.00e+00	733.00
IUUC-Dno-029103	Dasypus novemcinctus	74.92	0.00e+00	779.00
IUUC-Dme-031957	Drosophila melanogaster	65.05	7.00e-133	468.00
IUUC-Ete-033190	Echinops telfairi	82.19	0.00e+00	715.00
IUUC-Eca-033614	Equus caballus	57.95	2.00e-109	390.00
IUUC-Gmo-039423	Gadus morhua	59.83	0.00e+00	738.00
IUUC-Gga-040174	Gallus gallus	66.71	0.00e+00	919.00
IUUC-Gac-041875	Gasterosteus aculeatus	68.77	4.00e-155	542.00
IUUC-Ggo-045090	Gorilla gorilla	83.38	0.00e+00	1158.00
IUUC-Hsa-046775	Homo sapiens	84.06	0.00e+00	1147.00
IUUC-Itr-048715	Ictidomys tridecemlineatus	82.19	0.00e+00	1121.00
IUUC-Lch-049933	Latimeria chalumnae	57.39	0.00e+00	784.00
IUUC-Loc-052048	Lepisosteus oculatus	59.48	0.00e+00	803.00
IUUC-Laf-054466	Loxodonta africana	74.94	0.00e+00	1087.00
IUUC-Mcc-054655	Macaca mulatta	83.46	0.00e+00	1148.00
IUUC-Meu-056705	Macropus eugenii	74.66	0.00e+00	802.00
IUUC-Mmr-061419	Microcebus murinus	88.46	0.00e+00	1195.00
IUUC-Mdo-062854	Monodelphis domestica	69.84	0.00e+00	915.00
IUUC-Mmu-064252	Mus musculus	80.00	0.00e+00	1184.00
IUUC-Nle-069329	Nomascus leucogenys	80.13	0.00e+00	1090.00
IUUC-Opr-071101	Ochotona princeps	64.16	0.00e+00	669.00
IUUC-Ont-071887	Oreochromis niloticus	60.40	0.00e+00	709.00
IUUC-Oan-073050	Ornithorhynchus anatinus	74.61	0.00e+00	892.00
IUUC-Oar-089420	Ovis aries	73.97	0.00e+00	925.00
IUUC-Ptr-091258	Pan troglodytes	83.93	0.00e+00	1147.00
IUUC-Pan-092031	Papio anubis	83.72	0.00e+00	1151.00
IUUC-Pfo-097451	Poecilia formosa	62.58	0.00e+00	706.00
IUUC-Pab-097806	Pongo abelii	84.06	0.00e+00	1145.00
IUUC-Pva-102182	Pteropus vampyrus	71.39	0.00e+00	803.00
IUUC-Sha-107262	Sarcophilus harrisii	68.52	0.00e+00	977.00
IUUC-Ssc-115584	Sus scrofa	94.76	9.00e-144	502.00
IUUC-Tgu-116973	Taeniopygia guttata	65.88	0.00e+00	915.00
IUUC-Tru-117598	Takifugu rubripes	55.47	5.00e-117	416.00
IUUC-Tsy-119567	Tarsius syrichta	45.55	5.00e-114	405.00
IUUC-Tni-120589	Tetraodon nigroviridis	58.72	6.00e-117	415.00
IUUC-Tbe-127501	Tupaia belangeri	58.98	2.00e-123	437.00
IUUC-Ttr-128365	Tursiops truncatus	79.42	0.00e+00	845.00
IUUC-Xtr-131848	Xenopus tropicalis	59.80	9.00e-112	398.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence