iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-053459

Ensembl Protein ID

ENSLAFP00000010689.3

UniProt Accession

G3TA29; G3TA29_LOXAF

Protein Name

Non-specific serine/threonine protein kinase

Gene Name

PRKAA2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000012783.3	ENSLAFT00000012784.3	ENSLAFP00000010689.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	47.55	2.00e-123	439.00	IUUC-Ath-007014

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MAEKQKHDGR VKIGHYVLGD TLGVGTFGKV KIGEHQLTGH KVAVKILNRQ KIRSLDVVGK 60
IKREIQNLKL FRHPHIIKLY QVISTPTDFF MVMEYVSGGE LFDYICKHGR VEEMEARRLF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGAGA AGCAGAAGCA CGATGGGCGG GTGAAGATCG GACACTACGT GCTCGGGGAC 60
ACGCTGGGCG TCGGCACCTT CGGCAAAGTG AAGAGTTGAG TATGCGCTCG AGGCCGCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR032270--AMPK_C
IPR028375--KA1/Ssp2_C
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF16579--AdenylateSensor
PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005794--C:Golgi apparatus
GO:0016607--C:nuclear speck
GO:0004679--F:AMP-activated protein kinase activity
GO:0005524--F:ATP binding
GO:0003682--F:chromatin binding
GO:0035174--F:histone serine kinase activity
GO:0004712--F:protein serine/threonine/tyrosine kinase activity
GO:0035690--P:cellular response to drug
GO:0042149--P:cellular response to glucose starvation
GO:0071380--P:cellular response to prostaglandin E stimulus
GO:0042593--P:glucose homeostasis
GO:0008610--P:lipid biosynthetic process
GO:0043066--P:negative regulation of apoptotic process
GO:0032007--P:negative regulation of TOR signaling
GO:0010508--P:positive regulation of autophagy
GO:0042752--P:regulation of circadian rhythm
GO:0010468--P:regulation of gene expression
GO:0016241--P:regulation of macroautophagy
GO:0014850--P:response to muscle activity

KEGG

lav:100671280

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000713	Aegilops tauschii	47.01	8.00e-122	430.00
IUUC-Apl-003395	Anas platyrhynchos	94.06	0.00e+00	1025.00
IUUC-Aca-004480	Anolis carolinensis	93.40	0.00e+00	1026.00
IUUC-Aly-006289	Arabidopsis lyrata	47.44	8.00e-125	440.00
IUUC-Ath-007014	Arabidopsis thaliana	47.55	6.00e-125	441.00
IUUC-Ago-007957	Ashbya gossypii	43.20	9.00e-117	414.00
IUUC-Acl-008103	Aspergillus clavatus	60.07	4.00e-101	362.00
IUUC-Afl-008555	Aspergillus flavus	59.71	1.00e-101	363.00
IUUC-Afu-008949	Aspergillus fumigatus	60.07	3.00e-101	363.00
IUUC-Ani-009408	Aspergillus nidulans	62.17	1.00e-101	363.00
IUUC-Ang-009551	Aspergillus niger	60.07	5.00e-101	362.00
IUUC-Aor-010176	Aspergillus oryzae	59.71	2.00e-101	363.00
IUUC-Ate-010287	Aspergillus terreus	60.07	8.00e-101	361.00
IUUC-Ame-011019	Astyanax mexicanus	86.45	0.00e+00	1012.00
IUUC-Bgr-012045	Blumeria graminis	61.42	6.00e-102	364.00
IUUC-Bci-013774	Botrytis cinerea	48.43	2.00e-104	373.00
IUUC-Bdi-014319	Brachypodium distachyon	47.14	2.00e-124	439.00
IUUC-Bol-016242	Brassica oleracea	47.63	2.00e-127	449.00
IUUC-Bra-016750	Brassica rapa	47.84	8.00e-128	450.00
IUUC-Cel-018518	Caenorhabditis elegans	56.77	0.00e+00	627.00
IUUC-Cja-019386	Callithrix jacchus	98.01	0.00e+00	1100.00
IUUC-Cpo-021805	Cavia porcellus	98.01	0.00e+00	1098.00
IUUC-Csa-024267	Chlorocebus sabaeus	98.19	0.00e+00	1088.00
IUUC-Cin-025550	Ciona intestinalis	61.79	0.00e+00	674.00
IUUC-Csv-026139	Ciona savignyi	60.14	0.00e+00	672.00
IUUC-Cne-027044	Cryptococcus neoformans	51.03	3.00e-108	385.00
IUUC-Cme-027289	Cyanidioschyzon merolae	44.89	1.00e-111	396.00
IUUC-Dor-030578	Dipodomys ordii	97.83	0.00e+00	1098.00
IUUC-Dse-031507	Dothistroma septosporum	62.69	2.00e-104	374.00
IUUC-Dme-031704	Drosophila melanogaster	60.10	0.00e+00	663.00
IUUC-Eca-034016	Equus caballus	97.70	0.00e+00	1031.00
IUUC-Fox-038073	Fusarium oxysporum	52.20	1.00e-105	377.00
IUUC-Fso-038236	Fusarium solani	51.52	4.00e-102	365.00
IUUC-Ggr-039987	Gaeumannomyces graminis	49.32	2.00e-102	366.00
IUUC-Gga-040546	Gallus gallus	92.77	0.00e+00	1063.00
IUUC-Gac-041822	Gasterosteus aculeatus	84.35	0.00e+00	950.00
IUUC-Ggo-045303	Gorilla gorilla	98.37	0.00e+00	1105.00
IUUC-Hsa-045746	Homo sapiens	98.37	0.00e+00	1105.00
IUUC-Hvu-047406	Hordeum vulgare	46.94	6.00e-125	441.00
IUUC-Itr-048134	Ictidomys tridecemlineatus	98.37	0.00e+00	1103.00
IUUC-Kpa-049190	Komagataella pastoris	44.88	4.00e-122	431.00
IUUC-Loc-052928	Lepisosteus oculatus	90.05	0.00e+00	1032.00
IUUC-Lma-053054	Leptosphaeria maculans	62.92	5.00e-106	379.00
IUUC-Mcc-055862	Macaca mulatta	98.37	0.00e+00	1105.00
IUUC-Mpo-057302	Magnaporthe poae	49.45	3.00e-102	365.00
IUUC-Mla-059058	Melampsora laricipopulina	43.06	3.00e-104	372.00
IUUC-Mga-059206	Meleagris gallopavo	92.32	0.00e+00	1002.00
IUUC-Mvi-060337	Microbotryum violaceum	42.31	7.00e-109	388.00
IUUC-Mmr-061619	Microcebus murinus	97.10	0.00e+00	1085.00
IUUC-Mdo-062160	Monodelphis domestica	94.20	0.00e+00	1066.00
IUUC-Mmu-063406	Mus musculus	96.20	0.00e+00	1080.00
IUUC-Mac-064518	Musa acuminata	45.54	4.00e-121	428.00
IUUC-Mpu-066326	Mustela putorius furo	97.70	0.00e+00	1037.00
IUUC-Mlu-067968	Myotis lucifugus	96.40	0.00e+00	1003.00
IUUC-Nfi-068493	Neosartorya fischeri	60.07	3.00e-101	362.00
IUUC-Ncr-068665	Neurospora crassa	62.92	3.00e-105	375.00
IUUC-Nle-070158	Nomascus leucogenys	98.19	0.00e+00	1103.00
IUUC-Ont-071395	Oreochromis niloticus	86.20	0.00e+00	990.00
IUUC-Ogl-077718	Oryza glaberrima	50.11	3.00e-123	435.00
IUUC-Oin-079889	Oryza indica	45.81	7.00e-124	437.00
IUUC-Ola-087169	Oryzias latipes	84.23	0.00e+00	967.00
IUUC-Ptr-090741	Pan troglodytes	98.37	0.00e+00	1105.00
IUUC-Pfo-096295	Poecilia formosa	85.48	0.00e+00	980.00
IUUC-Pab-098023	Pongo abelii	98.37	0.00e+00	1105.00
IUUC-Pop-100042	Populus trichocarpa	47.77	2.00e-127	449.00
IUUC-Pva-102470	Pteropus vampyrus	97.10	0.00e+00	1085.00
IUUC-Pgr-103406	Puccinia graminis	61.36	6.00e-92	332.00
IUUC-Ptt-103713	Puccinia triticina	37.85	8.00e-79	288.00
IUUC-Pte-104259	Pyrenophora teres	62.55	3.00e-105	376.00
IUUC-Pyt-104752	Pyrenophora triticirepentis	62.92	7.00e-106	378.00
IUUC-Rno-104960	Rattus norvegicus	97.10	0.00e+00	1093.00
IUUC-Sce-106290	Saccharomyces cerevisiae	42.65	1.00e-117	416.00
IUUC-Sja-107772	Schizosaccharomyces japonicus	41.17	7.00e-110	390.00
IUUC-Ssl-108535	Sclerotinia sclerotiorum	47.71	5.00e-104	372.00
IUUC-Sly-110890	Solanum lycopersicum	48.28	8.00e-126	443.00
IUUC-Stu-112144	Solanum tuberosum	46.03	3.00e-118	418.00
IUUC-Sre-115141	Sporisorium reilianum	66.91	4.00e-115	409.00
IUUC-Tru-118735	Takifugu rubripes	84.59	0.00e+00	976.00
IUUC-Tsy-119503	Tarsius syrichta	94.62	0.00e+00	980.00
IUUC-Tni-119880	Tetraodon nigroviridis	84.97	0.00e+00	978.00
IUUC-Tca-121386	Theobroma cacao	47.46	2.00e-126	446.00
IUUC-Tvi-122305	Trichoderma virens	47.95	5.00e-102	365.00
IUUC-Tur-126416	Triticum urartu	46.85	2.00e-123	436.00
IUUC-Tbe-127791	Tupaia belangeri	86.09	2.00e-113	402.00
IUUC-Uma-129372	Ustilago maydis	66.91	2.00e-114	406.00
IUUC-Vda-129819	Verticillium dahliae	48.10	2.00e-86	313.00
IUUC-Vpa-130220	Vicugna pacos	97.88	0.00e+00	1032.00
IUUC-Xtr-132954	Xenopus tropicalis	92.59	0.00e+00	1067.00
IUUC-Xma-134119	Xiphophorus maculatus	85.30	0.00e+00	978.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence