iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011718

Ensembl Protein ID

ENSAMXP00000010817.1

UniProt Accession

W5KTA5; W5KTA5_ASTMX

Genbank Protein ID

ENSAMXP00000010817

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01085421

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000010534.1	ENSAMXT00000010817.1	ENSAMXP00000010817.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.60e-84	283.5	81	798

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.....kkkeklneenpkepkg........................ellkslqklfeel 60
           +Gl+NlgNtCY+NS+LQ+L+ +p ++e++++     k    l++++  +++g                        +l++s++++ +++
   Q: 81   VGLNNLGNTCYLNSILQVLYYCPGFKEAVKSlyqmsK----LKDKQ--KDDGvkseeqgescdstpvhmellssffSLISSVEQIQSSF 163
           6******************************644331....33332..22223344445666777777733443445555555555555 PP
   S: 61   w......kskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeed.kselsde............. 129
           +      ++ + a+ pr++l++l+k++++++gy q+DaqE+l+++l  ++e+++  k+++++++ee + +s  + +             
   Q: 164  LfnpdkySEGELATPPRRVLNTLRKLNPMYEGYLQHDAQEVLQCILAYIQEACDTIKKERRSDQEEPKkNSGEN-Detadevttaqeed 251
           45555435555599***************************************663333333333332023333.24788899****** PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 252  egsdgqlsgkrksdteagnakkkpksqskpkkseeenkpftrskrkssnditgnpvsdqkdepgieadgkeqekeggsnteeekiegnp 340
           ***************************************************************************************** PP
   S: 130  ..............................................................................aeekkkkknks 140
                                                                                           ++++ ++ +
   Q: 341  kevnkrkkraklgwlkssgkqpsifskfrsmgrisshagekaenkgddgktdddsqgpknqektiaetekpvenqvqsTTKSEELQGLD 429
           ************************************************************************9877766666777777* PP
   S: 141  lisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke..............slqdcLesftkeeelegenkyycekckkkq 215
           ++++lFqgql  +++clec+  ++r+e+f+d+s+pv+++e+++                +l++++++f++ e++ g++ky+ce+c++++
   Q: 430  VLKQLFQGQLVLRTRCLECECYTERREDFQDISVPVQEDETNSSDssseispdpkpeqkTLKWAISQFASVERIVGQDKYFCETCHHYT 518
           ***************************************9776669******************************************* PP
   S: 216  eaekklklkklPevLilhLkRf.....sfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvay 298
           eae++l ++k Pe+ ++hLk+f     + + +    +k+n+ +++pl+L+l+++ct+p++ + + + Y+L+avv+HsG ++ssGHY++y
   Q: 519  EAERSLLFDKTPEIVTIHLKCFsasgsELDPY-AGLSKVNTPLHTPLKLSLEEWCTRPSSPE-QGHHYKLFAVVMHSGiTISSGHYTTY 605
           **********************4444434444.4567********************99887.5************************* PP
   S: 299  vkn...................................................................................... 301
           ++                                                                                       
   Q: 606  IRMmdlhrtvlkpqsreerekeddgeinppkkeeapptdyddgevsfslsgkvktmtngtgsitstaskvggkrpsegvgllggqrsis 694
           ***************************************************************************************** PP
   S: 302  ..............................................................ekgkWllfdDskVtevkeeevleetg. 327
                                                                          +gkW+lfdDs+V+  +ee++l+ ++ 
   Q: 695  syelgssnkptssekpitvagctasapavqnggvkkekeddgdavkeetqvsvdlamqnlqdFEGKWMLFDDSEVRLFDEEDFLRACSp 783
           *************************************99999999999999999999888777999*******************999* PP
   S: 328  .....staYvlfYkr 337
                st+Y+lfYk+
   Q: 784  etcstSTPYLLFYKK 798
           *************97 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MPGLQAEGVV APLGSPNKKS RLSLRFFQKR ETKRALDFSE TPVEEPSTAE PEEAQSCDQV 60
VPVPCPFSVP CEKRESLVPF VGLNNLGNTC YLNSILQVLY YCPGFKEAVK SLYQMSKLKD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTTTTCCTG CAGGCGATGA AGGGGGGAGA ATTTGGGCGT GCATCTGCTG GAAAAAGCGC 60
CCGCCAAAGT TGTTCGCTGC GGCGAGAACC TCTGCGAAAT GTTCTGCGTC TGCAGCGAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001939	Ailuropoda melanoleuca	47.31	2.00e-175	608.00
IUUC-Apl-004204	Anas platyrhynchos	48.32	1.00e-163	570.00
IUUC-Aca-004637	Anolis carolinensis	48.48	2.00e-174	606.00
IUUC-Bta-012552	Bos taurus	47.90	3.00e-177	615.00
IUUC-Cja-019588	Callithrix jacchus	47.97	2.00e-180	625.00
IUUC-Cfa-020211	Canis familiaris	48.19	2.00e-175	609.00
IUUC-Cpo-021551	Cavia porcellus	47.69	1.00e-174	606.00
IUUC-Csa-024186	Chlorocebus sabaeus	48.20	9.00e-178	617.00
IUUC-Cho-024739	Choloepus hoffmanni	40.49	1.00e-74	274.00
IUUC-Dre-028184	Danio rerio	66.79	0.00e+00	874.00
IUUC-Dno-029669	Dasypus novemcinctus	48.55	0.00e+00	628.00
IUUC-Dor-030168	Dipodomys ordii	45.42	5.00e-155	541.00
IUUC-Dme-031732	Drosophila melanogaster	31.91	2.00e-19	91.70
IUUC-Ete-032825	Echinops telfairi	44.12	1.00e-111	397.00
IUUC-Eca-033595	Equus caballus	47.72	6.00e-165	574.00
IUUC-Eeu-034877	Erinaceus europaeus	48.36	3.00e-65	243.00
IUUC-Fca-035381	Felis catus	50.62	4.00e-130	458.00
IUUC-Fal-037592	Ficedula albicollis	50.42	1.00e-174	606.00
IUUC-Gmo-039680	Gadus morhua	56.34	0.00e+00	727.00
IUUC-Gga-041196	Gallus gallus	50.30	0.00e+00	634.00
IUUC-Gac-042292	Gasterosteus aculeatus	53.99	0.00e+00	652.00
IUUC-Ggo-044671	Gorilla gorilla	48.67	1.00e-178	620.00
IUUC-Hsa-047020	Homo sapiens	47.96	6.00e-178	617.00
IUUC-Itr-048800	Ictidomys tridecemlineatus	43.03	1.00e-149	523.00
IUUC-Lch-050543	Latimeria chalumnae	47.55	5.00e-159	554.00
IUUC-Loc-052338	Lepisosteus oculatus	58.93	0.00e+00	794.00
IUUC-Laf-053707	Loxodonta africana	47.74	2.00e-177	616.00
IUUC-Mcc-055885	Macaca mulatta	48.91	3.00e-179	622.00
IUUC-Meu-056573	Macropus eugenii	45.00	2.00e-147	516.00
IUUC-Mga-059346	Meleagris gallopavo	49.25	8.00e-169	587.00
IUUC-Mmr-061612	Microcebus murinus	48.31	1.00e-174	606.00
IUUC-Mdo-062887	Monodelphis domestica	49.23	1.00e-177	616.00
IUUC-Mmu-064044	Mus musculus	48.08	3.00e-173	602.00
IUUC-Mpu-066847	Mustela putorius furo	47.71	1.00e-176	613.00
IUUC-Mlu-067684	Myotis lucifugus	48.02	2.00e-174	605.00
IUUC-Nle-070057	Nomascus leucogenys	48.67	4.00e-178	618.00
IUUC-Opr-070463	Ochotona princeps	45.87	3.00e-119	422.00
IUUC-Ont-071975	Oreochromis niloticus	57.89	1.00e-167	583.00
IUUC-Oan-073062	Ornithorhynchus anatinus	57.69	9.00e-26	108.00
IUUC-Ocu-074840	Oryctolagus cuniculus	47.90	4.00e-177	614.00
IUUC-Ola-087088	Oryzias latipes	53.86	0.00e+00	723.00
IUUC-Oga-088472	Otolemur garnettii	47.61	1.00e-176	613.00
IUUC-Oar-089498	Ovis aries	48.30	5.00e-178	617.00
IUUC-Ptr-091395	Pan troglodytes	48.43	4.00e-178	618.00
IUUC-Pan-092462	Papio anubis	48.91	3.00e-179	622.00
IUUC-Psi-093583	Pelodiscus sinensis	48.31	3.00e-148	518.00
IUUC-Pma-094644	Petromyzon marinus	33.94	8.00e-24	103.00
IUUC-Pfo-096314	Poecilia formosa	55.09	0.00e+00	733.00
IUUC-Pab-098568	Pongo abelii	48.55	1.00e-178	619.00
IUUC-Pca-100948	Procavia capensis	45.18	3.00e-75	276.00
IUUC-Pva-102853	Pteropus vampyrus	48.35	1.00e-176	613.00
IUUC-Rno-105573	Rattus norvegicus	48.62	3.00e-175	608.00
IUUC-Sha-107495	Sarcophilus harrisii	48.35	7.00e-139	487.00
IUUC-Sar-113545	Sorex araneus	43.21	1.00e-135	477.00
IUUC-Ssc-115962	Sus scrofa	48.48	4.00e-180	624.00
IUUC-Tgu-116731	Taeniopygia guttata	49.70	5.00e-174	604.00
IUUC-Tru-117893	Takifugu rubripes	54.63	0.00e+00	696.00
IUUC-Tsy-119644	Tarsius syrichta	50.61	4.00e-74	272.00
IUUC-Tni-119819	Tetraodon nigroviridis	51.11	0.00e+00	678.00
IUUC-Tbe-127272	Tupaia belangeri	45.95	5.00e-146	511.00
IUUC-Ttr-128404	Tursiops truncatus	48.71	6.00e-179	621.00
IUUC-Vpa-130205	Vicugna pacos	48.09	7.00e-177	613.00
IUUC-Xtr-132613	Xenopus tropicalis	46.94	3.00e-163	568.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence