iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-001939

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Putative uncharacterized protein

Genbank Nucleotide ID

ACTA01049362

Gene Name

USP1; PANDA_006090

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000014832.1	ENSAMET00000016286.1	ENSAMEP00000015634.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.00e-85	285.7	81	785

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle......kkkeklneenpkepkg..........ellkslqklfeel.......w..... 61
           +Gl+NlgNtCY+NS+LQ+L+++p +++ +++      +kke+l+ee ++++kg          el++slq+l+ ++       +     
   Q: 81   VGLNNLGNTCYLNSILQVLYFCPGFKSGVKNlfniisRKKEALKEETNQKDKGnckedclasyELICSLQSLIISVeqlqasfLlnpek 169
           6***********************************999999999999999999999******99999999999995555555144555 PP
   S: 62   kskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkk.................eknkpkeeeeeedkselsde.... 129
           ++++ a++pr+ll++l++++++++gy q+DaqE+l+++l +++e+++                  ek ++kee+++ +++e+++     
   Q: 170  YTDELATQPRRLLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLlkkeevknvvelstkveEKPHQKEEMNGINSIEMDNLrhse 258
           88888*****************************************555556666666555555555555555555555555555**** PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 259  dykeklqkgngkrksdiefgnmkkkvklskehqsleenqrqtrskrkatggdtleipskiipkyvsenesarpsqkksrvkinwlkpat 347
           ***************************************************************************************** PP
   S: 130  ...................................................................aeekkkkknk.....slisdlF 146
                                                                                    +k+      +l+++lF
   Q: 348  kqpsilskfcslgkittnqgskgqskeneydleedlgkcenhnttngcelespgnnvkpvnvnevkpI-----NKGAeqigfELVEKLF 431
           ******************************************************99999998544443.....444455666******* PP
   S: 147  qgqlksqikclecdnvssreepfldlslpvpgkeetkke..............slqdcLesftkeeelegenkyycekckkkqeaekkl 221
           qgql  +++clec++ ++r+e+f+d+s+pv+++e +k e              +l++++++f++ e++ ge+ky+ce+c++++eae++l
   Q: 432  QGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEesseispepktemkTLRWAISQFASVERIVGEDKYFCENCHHYTEAERSL 520
           **********************************99998************************************************** PP
   S: 222  klkklPevLilhLkRf.....sfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn... 301
            ++k+Pev+++hLk+f     +f+++++  +kin+ + +pl+L+l+++ t+p+     +++Y L+avv+HsG ++ssGHY+a vk    
   Q: 521  LFDKMPEVITIHLKCFaasglEFDCYGGGLSKINTPLLTPLKLSLEEWSTKPT-----NDSYGLFAVVMHSGiTISSGHYTASVKVtdl 604
           ***************************************************99.....678**************************** PP
   S: 302  ......................................................................................... 301
                                                                                                    
   Q: 605  hsleldkgnfvidqmceigkpeplneeeargvvenyddeevsirvsgntqpskvlnkknaeaigllggqkskadyelynkasnpdkvas 693
           ***************************************************************************************** PP
   S: 302  ..................................................ekgkWllfdDskVtevkeeevleetg......staYvlf 334
                                                              +gkWllfdDs+V++++e+++l++ +      st+Y+lf
   Q: 694  tafvenrnsetnntngthefdtnkessdqaginfsgfenkisyvvqslkeYEGKWLLFDDSEVKVTEEKDFLNSLSpstsptSTPYLLF 782
           **************9999999999999999999999988888888877766999*******************888************* PP
   S: 335  Ykr 337
           Yk+
   Q: 783  YKK 785
           *97 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MPGVIPSESN GLSRGSPSKK NRLSLKFFQK KETKRALDFT DSQENEEKAA EYRGSEIDQV 60
VPAAQSSPIN CEKRENLLPF VGLNNLGNTC YLNSILQVLY FCPGFKSGVK NLFNIISRKK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCTGGTG TCATACCTAG TGAAAGTAAT GGGCTTTCAA GAGGTAGCCC ATCAAAGAAA 60
AACAGACTTT CCTTGAAGTT TTTTCAGAAA AAGGAAACTA AGAGAGCCTT GGATTTCACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033815--USP1
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0006282--P:regulation of DNA repair
GO:0009411--P:response to UV
GO:0001501--P:skeletal system development
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

aml:100473360

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004204	Anas platyrhynchos	73.45	0.00e+00	941.00
IUUC-Aca-004637	Anolis carolinensis	66.00	0.00e+00	936.00
IUUC-Ame-011718	Astyanax mexicanus	47.54	2.00e-172	599.00
IUUC-Bta-012552	Bos taurus	92.49	0.00e+00	1415.00
IUUC-Cja-019588	Callithrix jacchus	93.77	0.00e+00	1464.00
IUUC-Cfa-020211	Canis familiaris	96.69	0.00e+00	1474.00
IUUC-Cpo-021551	Cavia porcellus	82.19	0.00e+00	1247.00
IUUC-Csa-024186	Chlorocebus sabaeus	93.77	0.00e+00	1465.00
IUUC-Cho-024739	Choloepus hoffmanni	84.30	0.00e+00	763.00
IUUC-Dre-028184	Danio rerio	49.33	8.00e-178	617.00
IUUC-Dno-029669	Dasypus novemcinctus	89.73	0.00e+00	1387.00
IUUC-Dor-030168	Dipodomys ordii	85.80	0.00e+00	1233.00
IUUC-Dme-031732	Drosophila melanogaster	28.77	7.00e-18	86.30
IUUC-Ete-032825	Echinops telfairi	86.83	0.00e+00	960.00
IUUC-Eca-033595	Equus caballus	92.59	0.00e+00	1340.00
IUUC-Eeu-034877	Erinaceus europaeus	80.56	5.00e-161	561.00
IUUC-Fca-035381	Felis catus	95.94	0.00e+00	1036.00
IUUC-Fal-037592	Ficedula albicollis	69.42	0.00e+00	971.00
IUUC-Gmo-039680	Gadus morhua	45.37	2.00e-154	539.00
IUUC-Gga-041196	Gallus gallus	72.82	0.00e+00	1060.00
IUUC-Gac-042292	Gasterosteus aculeatus	49.45	8.00e-146	510.00
IUUC-Ggo-044671	Gorilla gorilla	94.02	0.00e+00	1471.00
IUUC-Hsa-047020	Homo sapiens	94.40	0.00e+00	1472.00
IUUC-Itr-048800	Ictidomys tridecemlineatus	84.63	0.00e+00	1255.00
IUUC-Lch-050543	Latimeria chalumnae	58.32	0.00e+00	705.00
IUUC-Loc-052338	Lepisosteus oculatus	52.55	0.00e+00	690.00
IUUC-Laf-053707	Loxodonta africana	90.51	0.00e+00	1412.00
IUUC-Mcc-055885	Macaca mulatta	94.02	0.00e+00	1469.00
IUUC-Meu-056573	Macropus eugenii	66.83	0.00e+00	953.00
IUUC-Mga-059346	Meleagris gallopavo	73.16	0.00e+00	1010.00
IUUC-Mmr-061612	Microcebus murinus	93.26	0.00e+00	1385.00
IUUC-Mdo-062887	Monodelphis domestica	72.65	0.00e+00	1054.00
IUUC-Mmu-064044	Mus musculus	87.04	0.00e+00	1343.00
IUUC-Mpu-066847	Mustela putorius furo	97.46	0.00e+00	1483.00
IUUC-Mlu-067684	Myotis lucifugus	90.99	0.00e+00	1417.00
IUUC-Nle-070057	Nomascus leucogenys	94.02	0.00e+00	1472.00
IUUC-Opr-070463	Ochotona princeps	82.68	0.00e+00	1233.00
IUUC-Ont-071975	Oreochromis niloticus	46.14	2.00e-151	530.00
IUUC-Oan-073062	Ornithorhynchus anatinus	85.71	4.00e-47	180.00
IUUC-Ocu-074840	Oryctolagus cuniculus	92.37	0.00e+00	1414.00
IUUC-Ola-087088	Oryzias latipes	46.36	6.00e-174	604.00
IUUC-Oga-088472	Otolemur garnettii	91.98	0.00e+00	1418.00
IUUC-Oar-089498	Ovis aries	92.37	0.00e+00	1410.00
IUUC-Ptr-091395	Pan troglodytes	94.02	0.00e+00	1467.00
IUUC-Pan-092462	Papio anubis	94.15	0.00e+00	1469.00
IUUC-Psi-093583	Pelodiscus sinensis	72.85	0.00e+00	920.00
IUUC-Pma-094644	Petromyzon marinus	36.73	4.00e-28	117.00
IUUC-Pfo-096314	Poecilia formosa	47.24	8.00e-168	584.00
IUUC-Pab-098568	Pongo abelii	94.53	0.00e+00	1479.00
IUUC-Pca-100948	Procavia capensis	81.22	0.00e+00	1239.00
IUUC-Pva-102853	Pteropus vampyrus	93.12	0.00e+00	1431.00
IUUC-Rno-105573	Rattus norvegicus	88.17	0.00e+00	1340.00
IUUC-Sha-107495	Sarcophilus harrisii	71.88	0.00e+00	890.00
IUUC-Sar-113545	Sorex araneus	76.94	0.00e+00	1097.00
IUUC-Ssc-115962	Sus scrofa	93.54	0.00e+00	1450.00
IUUC-Tgu-116731	Taeniopygia guttata	69.99	0.00e+00	983.00
IUUC-Tru-117893	Takifugu rubripes	46.59	8.00e-159	554.00
IUUC-Tsy-119644	Tarsius syrichta	83.31	0.00e+00	1245.00
IUUC-Tni-119819	Tetraodon nigroviridis	44.02	1.00e-169	590.00
IUUC-Tbe-127272	Tupaia belangeri	88.49	0.00e+00	1256.00
IUUC-Ttr-128404	Tursiops truncatus	93.25	0.00e+00	1439.00
IUUC-Vpa-130205	Vicugna pacos	92.61	0.00e+00	1432.00
IUUC-Xtr-132613	Xenopus tropicalis	55.90	0.00e+00	747.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence