iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037592

Ensembl Protein ID

ENSFALP00000013047.1

UniProt Accession

U3KDE3; U3KDE3_FICAL

Genbank Protein ID

ENSFALP00000013047

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01021218

Gene Name

USP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000012495.1	ENSFALT00000013101.1	ENSFALP00000013047.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.90e-88	296.5	79	778

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle......kkkeklneenpkepkg.................ellkslqklfeel...... 60
           +Gl+NlgNtCY+NSvLQ+L+++p ++  +++      kk+e+ ++e      g                 el++sl++l+ ++      
   Q: 79   VGLNNLGNTCYLNSVLQVLYFCPGFKTGVKHlyniisKKRESSKDE------GeqkaekgsckedplasyELICSLHSLILSVeqlqas 161
           6******************************776665333333333......2333355788999999998888888888887554444 PP
   S: 61   .w.....kskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkk...........eknkpkeeeeeedkselsde... 129
            +     ++++ a++pr+ll++l++++++++gy q+DaqE+l+++l +++e+++            e  +p  ++ee+++     +   
   Q: 162  fLlnpekYTDELATQPRRLLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLlkkeelnklpvE--EPAAKLEEKAN-----Qtse 243
           425555588888*****************************************55555666666331..33333333332.....1334 PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 244  sngsvspaeeedptlgshggdaakekllkgngkrksdaeggnakkkskvskeqiaaeehqrqtrskrkatgekmenqtdaiakcsgese 332
           447788999999***************************************************************************** PP
   S: 130  .......................................................................................ae 131
                                                                                                  ++
   Q: 333  sakptqkksrlrlnwlkssckqpsilskfyslgklttnlgskdpgkeydcefeesavkcengdskeeyhepaspveshhgkgtekepKK 421
           ******************************************************************************99886544444 PP
   S: 132  ekkkkknk....slisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke..............slqdcLesftkeeeleg 202
           e +    +    +l+++lFqgql  +++clec+  ++r+e+f+d+s+pv+++e +k e              +l++++++f++ e++ g
   Q: 422  EGT----ElavfELVERLFQGQLVLRTRCLECECFTERREDFQDISVPVQEDELSKSEesseispepktemkTLKWAISQFASVERIVG 506
           444....25566*****************************************988779****************************** PP
   S: 203  enkyycekckkkqeaekklklkklPevLilhLkRf.....sfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvH 286
           e+ky+ce+c++++eae++l ++k+Pev+++hLk+f     +f+++++  +kin+ + +pl+L+l+++ t+p+     +++Y L+avv+H
   Q: 507  EDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFaasglEFDCYGGL-SKINTPLLTPLRLSLEEWSTRPT-----NDTYGLFAVVMH 589
           ********************************************9555.6********************98.....789********* PP
   S: 287  sG.slssGHYvayvkn......................................................................... 301
           sG ++ssGHY+a vk                                                                          
   Q: 590  SGiTISSGHYTASVKVtdlqsleldrgnflpepgyaalkpeplteeearavaedyddgevsfrlngaappgkvlgkksteavgllggqk 678
           ***************************************************************************************** PP
   S: 302  ..........................................................ekgkWllfdDskVtevkeeevleetg..... 327
                                                                      +gkWllfdDs+V++++e+++l++ +     
   Q: 679  skadcelcaskqpnpekllsaapeprgaqpgpqqgeppalaaaglenkalyvlqslkeYEGKWLLFDDSEVKVTEEKDFLNSLSptsss 767
           *************************9999999999999999999998888888887766999*******************888***** PP
   S: 328  .staYvlfYkr 337
            st+Y+lfYk+
   Q: 768  tSTPYLLFYKK 778
           *********97 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MPGVLPGDSA RASPSKKNRL SLKLFQKKEA KRVLDFIEAQ ENEPKGAEFR GAEIDQVVPA 60
AQPPSLVSCE KKDNMLPFVG LNNLGNTCYL NSVLQVLYFC PGFKTGVKHL YNIISKKRES 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGTAAA 60
TGGCGCCTGG TGTGCGCGTG TGTGTGTGTG TGCGCGCCAG GTGTGAGCGC CCCGGCCGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033815--USP1
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0006282--P:regulation of DNA repair
GO:0009411--P:response to UV
GO:0001501--P:skeletal system development
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

fab:101819959

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001939	Ailuropoda melanoleuca	70.23	0.00e+00	1001.00
IUUC-Apl-004204	Anas platyrhynchos	85.35	0.00e+00	1076.00
IUUC-Aca-004637	Anolis carolinensis	70.08	0.00e+00	969.00
IUUC-Ame-011718	Astyanax mexicanus	49.70	4.00e-176	611.00
IUUC-Bta-012552	Bos taurus	68.88	0.00e+00	991.00
IUUC-Cja-019588	Callithrix jacchus	70.19	0.00e+00	999.00
IUUC-Cfa-020211	Canis familiaris	70.60	0.00e+00	1008.00
IUUC-Cpo-021551	Cavia porcellus	66.92	0.00e+00	934.00
IUUC-Csa-024186	Chlorocebus sabaeus	70.14	0.00e+00	997.00
IUUC-Cho-024739	Choloepus hoffmanni	60.80	4.00e-150	524.00
IUUC-Dre-028184	Danio rerio	50.06	1.00e-176	613.00
IUUC-Dno-029669	Dasypus novemcinctus	68.46	0.00e+00	984.00
IUUC-Dor-030168	Dipodomys ordii	65.29	0.00e+00	900.00
IUUC-Dme-031732	Drosophila melanogaster	29.38	1.00e-16	82.00
IUUC-Ete-032825	Echinops telfairi	64.70	0.00e+00	641.00
IUUC-Eca-033595	Equus caballus	69.73	0.00e+00	911.00
IUUC-Eeu-034877	Erinaceus europaeus	70.40	1.00e-119	423.00
IUUC-Fca-035381	Felis catus	70.73	0.00e+00	715.00
IUUC-Gmo-039680	Gadus morhua	46.86	5.00e-155	541.00
IUUC-Gga-041196	Gallus gallus	83.94	0.00e+00	1180.00
IUUC-Gac-042292	Gasterosteus aculeatus	48.19	4.00e-139	488.00
IUUC-Ggo-044671	Gorilla gorilla	70.12	0.00e+00	995.00
IUUC-Hsa-047020	Homo sapiens	70.12	0.00e+00	999.00
IUUC-Itr-048800	Ictidomys tridecemlineatus	63.11	0.00e+00	859.00
IUUC-Lch-050543	Latimeria chalumnae	58.12	0.00e+00	689.00
IUUC-Loc-052338	Lepisosteus oculatus	53.25	0.00e+00	682.00
IUUC-Laf-053707	Loxodonta africana	69.33	0.00e+00	991.00
IUUC-Mcc-055885	Macaca mulatta	70.14	0.00e+00	1001.00
IUUC-Meu-056573	Macropus eugenii	61.98	0.00e+00	829.00
IUUC-Mga-059346	Meleagris gallopavo	85.56	0.00e+00	1170.00
IUUC-Mmr-061612	Microcebus murinus	68.71	0.00e+00	988.00
IUUC-Mdo-062887	Monodelphis domestica	68.51	0.00e+00	952.00
IUUC-Mmu-064044	Mus musculus	69.41	0.00e+00	984.00
IUUC-Mpu-066847	Mustela putorius furo	70.31	0.00e+00	1008.00
IUUC-Mlu-067684	Myotis lucifugus	70.59	0.00e+00	996.00
IUUC-Nle-070057	Nomascus leucogenys	69.88	0.00e+00	994.00
IUUC-Opr-070463	Ochotona princeps	63.20	0.00e+00	865.00
IUUC-Ont-071975	Oreochromis niloticus	50.22	2.00e-139	489.00
IUUC-Oan-073062	Ornithorhynchus anatinus	70.87	5.00e-38	149.00
IUUC-Ocu-074840	Oryctolagus cuniculus	68.78	0.00e+00	995.00
IUUC-Ola-087088	Oryzias latipes	47.96	2.00e-167	582.00
IUUC-Oga-088472	Otolemur garnettii	69.88	0.00e+00	985.00
IUUC-Oar-089498	Ovis aries	69.18	0.00e+00	988.00
IUUC-Ptr-091395	Pan troglodytes	70.12	0.00e+00	998.00
IUUC-Pan-092462	Papio anubis	70.26	0.00e+00	1002.00
IUUC-Psi-093583	Pelodiscus sinensis	77.73	0.00e+00	959.00
IUUC-Pma-094644	Petromyzon marinus	36.93	2.00e-28	118.00
IUUC-Pfo-096314	Poecilia formosa	46.61	2.00e-158	552.00
IUUC-Pab-098568	Pongo abelii	69.88	0.00e+00	998.00
IUUC-Pca-100948	Procavia capensis	66.42	1.00e-144	506.00
IUUC-Pva-102853	Pteropus vampyrus	70.14	0.00e+00	996.00
IUUC-Rno-105573	Rattus norvegicus	70.00	0.00e+00	1000.00
IUUC-Sha-107495	Sarcophilus harrisii	67.72	0.00e+00	785.00
IUUC-Sar-113545	Sorex araneus	58.52	0.00e+00	738.00
IUUC-Ssc-115962	Sus scrofa	69.33	0.00e+00	991.00
IUUC-Tgu-116731	Taeniopygia guttata	94.63	0.00e+00	1373.00
IUUC-Tru-117893	Takifugu rubripes	47.55	9.00e-156	543.00
IUUC-Tsy-119644	Tarsius syrichta	64.59	7.00e-135	474.00
IUUC-Tni-119819	Tetraodon nigroviridis	46.79	1.00e-163	570.00
IUUC-Tbe-127272	Tupaia belangeri	65.86	0.00e+00	860.00
IUUC-Ttr-128404	Tursiops truncatus	69.97	0.00e+00	982.00
IUUC-Vpa-130205	Vicugna pacos	69.80	0.00e+00	986.00
IUUC-Xtr-132613	Xenopus tropicalis	55.16	0.00e+00	705.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence