iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074840

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02002409

Gene Name

USP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000012942.3	ENSOCUT00000012941.3	ENSOCUP00000011141.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.50e-85	285.1	81	784

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle......kkkeklneenpkepkg..........ellkslqklfeel.......w..... 61
           +Gl+NlgNtCY+NS+LQ+L+++p +++ +++      +kke+l++e+++ +kg          el++slq+l+ ++       +     
   Q: 81   VGLNNLGNTCYLNSILQVLYFCPGFKSGVKHlfniisRKKEALKDEASQRDKGnckedslasyELICSLQSLIISVeqlqasfLlnpek 169
           6***********************************99999999999888888999999999999999999999995555555144555 PP
   S: 62   kskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkk.................eknkpkeeeeeedkselsde.... 129
           ++++ a++pr+ll++l++++++++gy q+DaqE+l+++l +++e+++                  ek ++              +    
   Q: 170  YTDELATQPRRLLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLlkkeevknvaelptkveEKLHQ--------------Keets 244
           88888*****************************************546666666665444443322222..............13333 PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 245  dmnnaetdnirnsedykeklpkgngkrksdsefgnmkkkvkvskeyqsleenqrqtrskrkatsdtleipskiipkcisendstrpsqk 333
           335666667799999************************************************************************** PP
   S: 130  ...........................................................................aeekkkkknk.... 139
                                                                                      +e k+ +k+     
   Q: 334  ksrvkinwlkssakqpsilskfcslgkittnqgskgqfqeneydleedlgkcetdnttnvcgldspenkvkpvnvNEAKPINKGAeqig 422
           *******************************************************************9999998844444444445666 PP
   S: 140  .slisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke..............slqdcLesftkeeelegenkyycekckk 213
            +l+++lFqgql  +++clec++ ++r+e+f+d+s+pv+++e +k e              +l++++++f++ e++ ge+ky+ce+c++
   Q: 423  fELVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEesseispepktemkTLRWAISQFASVERIVGEDKYFCENCHH 511
           6*****************************************99998****************************************** PP
   S: 214  kqeaekklklkklPevLilhLkRf.....sfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYv 296
           ++eae++l ++k+Pev+++hLk+f     +f+++++  +kin+ + +pl+L+l+++ t+p+     +++Y L+avv+HsG ++ssGHY+
   Q: 512  YTEAERSLLFDKMPEVITIHLKCFaasglEFDCYGGGLSKINTPLLTPLKLSLEEWSTKPT-----NDSYGLFAVVMHSGiTISSGHYT 595
           ***********************************************************99.....678******************** PP
   S: 297  ayvkn.................................................................................... 301
           a vk                                                                                     
   Q: 596  ASVKVtdlnsleldkgnfvvdqmceigkqeplndeeakgvvenydeeevsirvggntqpskvlnkknveaigllggqkskadyelynka 684
           ***************************************************************************************** PP
   S: 302  ..........................................................ekgkWllfdDskVtevkeeevleetg..... 327
                                                                      +gkWllfdDs+V++++e+++l++ +     
   Q: 685  snpdkvastaftenrnsetnstngthesdrnkdssdqtgvnmngfenkisyvvqslkeYEGKWLLFDDSEVKVTEEKDFLNSLSpstsp 773
           **********************9999999999999999999999888888888877766999*******************888***** PP
   S: 328  .staYvlfYkr 337
            st+Y+lfYk+
   Q: 774  tSTPYLLFYKK 784
           *********97 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MPGVIPSESN GLSRGSPSKK NRLSLKFFQK KETKRALDFT DSQESEEKAS EYRGSEIDQV 60
VPAAQSSPIN CEKRENLLPF VGLNNLGNTC YLNSILQVLY FCPGFKSGVK HLFNIISRKK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATATAACTGG TGATTACAGC TGCCCTCCGT ATATTAATTC TTGTCAACTC CTTTGGATTT 60
GAAGAGAAAA TGCCTGGTGT CATACCTAGT GAAAGTAATG GGCTTTCAAG AGGTAGTCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033815--USP1
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0006282--P:regulation of DNA repair
GO:0009411--P:response to UV
GO:0001501--P:skeletal system development
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ocu:100358366

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001939	Ailuropoda melanoleuca	92.37	0.00e+00	1407.00
IUUC-Apl-004204	Anas platyrhynchos	71.62	0.00e+00	935.00
IUUC-Aca-004637	Anolis carolinensis	65.66	0.00e+00	926.00
IUUC-Ame-011718	Astyanax mexicanus	48.19	1.00e-170	593.00
IUUC-Bta-012552	Bos taurus	91.08	0.00e+00	1401.00
IUUC-Cja-019588	Callithrix jacchus	93.12	0.00e+00	1458.00
IUUC-Cfa-020211	Canis familiaris	93.12	0.00e+00	1432.00
IUUC-Cpo-021551	Cavia porcellus	83.18	0.00e+00	1271.00
IUUC-Csa-024186	Chlorocebus sabaeus	93.63	0.00e+00	1469.00
IUUC-Cho-024739	Choloepus hoffmanni	81.68	0.00e+00	742.00
IUUC-Dre-028184	Danio rerio	49.45	5.00e-176	611.00
IUUC-Dno-029669	Dasypus novemcinctus	88.71	0.00e+00	1372.00
IUUC-Dor-030168	Dipodomys ordii	85.53	0.00e+00	1246.00
IUUC-Dme-031732	Drosophila melanogaster	30.39	1.00e-17	85.50
IUUC-Ete-032825	Echinops telfairi	86.98	0.00e+00	962.00
IUUC-Eca-033595	Equus caballus	91.35	0.00e+00	1323.00
IUUC-Eeu-034877	Erinaceus europaeus	79.67	7.00e-159	554.00
IUUC-Fca-035381	Felis catus	91.87	0.00e+00	993.00
IUUC-Fal-037592	Ficedula albicollis	68.12	0.00e+00	966.00
IUUC-Gmo-039680	Gadus morhua	44.23	2.00e-151	529.00
IUUC-Gga-041196	Gallus gallus	72.25	0.00e+00	1065.00
IUUC-Gac-042292	Gasterosteus aculeatus	49.29	7.00e-146	511.00
IUUC-Ggo-044671	Gorilla gorilla	93.38	0.00e+00	1465.00
IUUC-Hsa-047020	Homo sapiens	93.12	0.00e+00	1458.00
IUUC-Itr-048800	Ictidomys tridecemlineatus	83.59	0.00e+00	1254.00
IUUC-Lch-050543	Latimeria chalumnae	57.37	0.00e+00	706.00
IUUC-Loc-052338	Lepisosteus oculatus	52.79	0.00e+00	702.00
IUUC-Laf-053707	Loxodonta africana	89.99	0.00e+00	1407.00
IUUC-Mcc-055885	Macaca mulatta	93.89	0.00e+00	1473.00
IUUC-Meu-056573	Macropus eugenii	66.71	0.00e+00	957.00
IUUC-Mga-059346	Meleagris gallopavo	72.46	0.00e+00	1017.00
IUUC-Mmr-061612	Microcebus murinus	91.59	0.00e+00	1376.00
IUUC-Mdo-062887	Monodelphis domestica	72.12	0.00e+00	1049.00
IUUC-Mmu-064044	Mus musculus	87.40	0.00e+00	1356.00
IUUC-Mpu-066847	Mustela putorius furo	93.38	0.00e+00	1430.00
IUUC-Mlu-067684	Myotis lucifugus	89.45	0.00e+00	1395.00
IUUC-Nle-070057	Nomascus leucogenys	93.38	0.00e+00	1469.00
IUUC-Opr-070463	Ochotona princeps	85.33	0.00e+00	1276.00
IUUC-Ont-071975	Oreochromis niloticus	46.42	3.00e-153	535.00
IUUC-Oan-073062	Ornithorhynchus anatinus	85.71	7.00e-47	179.00
IUUC-Ola-087088	Oryzias latipes	47.24	5.00e-175	607.00
IUUC-Oga-088472	Otolemur garnettii	91.72	0.00e+00	1412.00
IUUC-Oar-089498	Ovis aries	91.34	0.00e+00	1409.00
IUUC-Ptr-091395	Pan troglodytes	93.38	0.00e+00	1461.00
IUUC-Pan-092462	Papio anubis	94.01	0.00e+00	1474.00
IUUC-Psi-093583	Pelodiscus sinensis	71.73	0.00e+00	910.00
IUUC-Pma-094644	Petromyzon marinus	36.36	2.00e-28	119.00
IUUC-Pfo-096314	Poecilia formosa	47.24	3.00e-170	592.00
IUUC-Pab-098568	Pongo abelii	93.76	0.00e+00	1470.00
IUUC-Pca-100948	Procavia capensis	81.07	0.00e+00	1241.00
IUUC-Pva-102853	Pteropus vampyrus	91.33	0.00e+00	1406.00
IUUC-Rno-105573	Rattus norvegicus	87.77	0.00e+00	1345.00
IUUC-Sha-107495	Sarcophilus harrisii	71.86	0.00e+00	889.00
IUUC-Sar-113545	Sorex araneus	76.28	0.00e+00	1092.00
IUUC-Ssc-115962	Sus scrofa	92.14	0.00e+00	1434.00
IUUC-Tgu-116731	Taeniopygia guttata	68.92	0.00e+00	982.00
IUUC-Tru-117893	Takifugu rubripes	46.72	2.00e-159	556.00
IUUC-Tsy-119644	Tarsius syrichta	82.78	0.00e+00	1236.00
IUUC-Tni-119819	Tetraodon nigroviridis	43.85	9.00e-170	590.00
IUUC-Tbe-127272	Tupaia belangeri	86.56	0.00e+00	1224.00
IUUC-Ttr-128404	Tursiops truncatus	92.22	0.00e+00	1429.00
IUUC-Vpa-130205	Vicugna pacos	91.07	0.00e+00	1412.00
IUUC-Xtr-132613	Xenopus tropicalis	55.04	0.00e+00	735.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence