iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-116731

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01030743

Gene Name

USP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000009799.1	ENSTGUT00000010222.1	ENSTGUP00000010115.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.40e-88	297.1	79	776

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle......kkkeklneenpkepkg.................ellkslqklfeel...... 60
           +Gl+NlgNtCY+NSvLQ+L+++p ++  +++      kk+e+ ++e      g                 el++sl++l+ ++      
   Q: 79   VGLNNLGNTCYLNSVLQVLYFCPGFKTGVKHlyniisKKRESSKDE------GeqkaekgsckedplasyELICSLHSLILSVeqlqas 161
           6******************************776665333333333......2333355788999999998888888888887554444 PP
   S: 61   .w.....kskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkk...........eknkpkeeeeeedkselsde... 129
            +     ++++ a++pr+ll++l++++++++gy q+DaqE+l+++l +++e+++            e+   k ee+ +       +   
   Q: 162  fLlnpekYTDELATQPRRLLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLlkkeelnklpvEEPAAKLEEKPN-------Qnse 243
           425555588888*****************************************5555565555543222222222222.......1444 PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 244  sngsaedptpgshggdaakekllkangkrksdaeggnakkkskvskeqiaaeenqrqtrskrkatgekmenqtdaiakcsgdsesakpt 332
           446689999******************************************************************************** PP
   S: 130  ..................................................................................aeekkkk 136
                                                                                             ++e +  
   Q: 333  qkksrlrlnwlksscrqpsilskfyslgklttnlgskepgkeydcefeesavkcengdskeeyrepaspleshhgkgtekepKKEGT-- 419
           **************************************************************************9986544444444.. PP
   S: 137  knk....slisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke..............slqdcLesftkeeelegenkyy 207
             +    +l+++lFqgql  +++clec+  ++r+e+f+d+s+pv+++e +k e              +l++++++f++ e++ ge+ky+
   Q: 420  --ElavfELVEKLFQGQLVLRTRCLECECFTERREDFQDISVPVQEDELSKSEesseispepktemkTLKWAISQFASVERIVGEDKYF 506
           ..25566*****************************************988779*********************************** PP
   S: 208  cekckkkqeaekklklkklPevLilhLkRf.....sfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.sl 290
           ce+c++++eae++l ++k+Pev+++hLk+f     +f+++++  +kin+ + +pl+L+l+++ t+p+     +++Y L+avv+HsG ++
   Q: 507  CENCHHYTEAERSLLFDKMPEVITIHLKCFaasglEFDCYGGL-SKINTPLLTPLRLSLEEWSTRPT-----NDTYGLFAVVMHSGiTI 589
           ***************************************9555.6********************98.....789************** PP
   S: 291  ssGHYvayvkn.............................................................................. 301
           ssGHY+a vk                                                                               
   Q: 590  SSGHYTASVKVtdlqsleldrgnflpepgyaalkpeplteeearavaedyddgevsfrpsgaappgkvlskknmeavgllggqkskadc 678
           ***************************************************************************************** PP
   S: 302  ........................................................ekgkWllfdDskVtevkeeevleetg......s 328
                                                                    +gkWllfdDs+V++++e+++l++ +      s
   Q: 679  elcaskqpnpekllsvapeprsepsaepraeqgeptalganglenkalyvlqslkeYEGKWLLFDDSEVKVTEEKDFLNSLSptssstS 767
           **********************99999999999999999999998888888887766999*******************888******* PP
   S: 329  taYvlfYkr 337
           t+Y+lfYk+
   Q: 768  TPYLLFYKK 776
           *******97 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MPGVLPGDSA RASPSKKNRL SLKLFQKKEA KRVLDFVEAQ ENEAKGAELR GAEIDQVVPA 60
AQPPSLVSCE KKDNMLPFVG LNNLGNTCYL NSVLQVLYFC PGFKTGVKHL YNIISKKRES 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCCGGCG TCCTGCCCGG CGACAGCGCC AGGGCCAGCC CCTCCAAGAA GAACCGGCTG 60
TCGCTGAAGC TGTTTCAGAA GAAGGAGGCG AAGCGGGTGC TGGATTTCGT GGAGGCGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033815--USP1
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0006282--P:regulation of DNA repair
GO:0009411--P:response to UV
GO:0001501--P:skeletal system development
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001939	Ailuropoda melanoleuca	70.54	0.00e+00	1004.00
IUUC-Apl-004204	Anas platyrhynchos	84.92	0.00e+00	1067.00
IUUC-Aca-004637	Anolis carolinensis	70.05	0.00e+00	962.00
IUUC-Ame-011718	Astyanax mexicanus	49.27	3.00e-175	608.00
IUUC-Bta-012552	Bos taurus	69.32	0.00e+00	995.00
IUUC-Cja-019588	Callithrix jacchus	70.13	0.00e+00	1004.00
IUUC-Cfa-020211	Canis familiaris	71.34	0.00e+00	1018.00
IUUC-Cpo-021551	Cavia porcellus	67.59	0.00e+00	937.00
IUUC-Csa-024186	Chlorocebus sabaeus	70.20	0.00e+00	1003.00
IUUC-Cho-024739	Choloepus hoffmanni	61.49	1.00e-150	526.00
IUUC-Dre-028184	Danio rerio	49.63	1.00e-175	609.00
IUUC-Dno-029669	Dasypus novemcinctus	68.89	0.00e+00	986.00
IUUC-Dor-030168	Dipodomys ordii	65.45	0.00e+00	903.00
IUUC-Dme-031732	Drosophila melanogaster	28.63	7.00e-17	82.80
IUUC-Ete-032825	Echinops telfairi	65.14	0.00e+00	644.00
IUUC-Eca-033595	Equus caballus	70.20	0.00e+00	921.00
IUUC-Eeu-034877	Erinaceus europaeus	71.20	7.00e-122	431.00
IUUC-Fca-035381	Felis catus	70.83	0.00e+00	718.00
IUUC-Fal-037592	Ficedula albicollis	94.76	0.00e+00	1352.00
IUUC-Gmo-039680	Gadus morhua	46.43	2.00e-154	538.00
IUUC-Gga-041196	Gallus gallus	83.90	0.00e+00	1175.00
IUUC-Gac-042292	Gasterosteus aculeatus	45.13	7.00e-149	520.00
IUUC-Ggo-044671	Gorilla gorilla	70.06	0.00e+00	1001.00
IUUC-Hsa-047020	Homo sapiens	70.06	0.00e+00	1005.00
IUUC-Itr-048800	Ictidomys tridecemlineatus	63.64	0.00e+00	870.00
IUUC-Lch-050543	Latimeria chalumnae	58.65	0.00e+00	687.00
IUUC-Loc-052338	Lepisosteus oculatus	53.28	0.00e+00	677.00
IUUC-Laf-053707	Loxodonta africana	69.76	0.00e+00	1003.00
IUUC-Mcc-055885	Macaca mulatta	70.08	0.00e+00	1006.00
IUUC-Meu-056573	Macropus eugenii	63.13	0.00e+00	836.00
IUUC-Mga-059346	Meleagris gallopavo	85.28	0.00e+00	1156.00
IUUC-Mmr-061612	Microcebus murinus	69.28	0.00e+00	993.00
IUUC-Mdo-062887	Monodelphis domestica	69.18	0.00e+00	961.00
IUUC-Mmu-064044	Mus musculus	69.72	0.00e+00	991.00
IUUC-Mpu-066847	Mustela putorius furo	70.76	0.00e+00	1016.00
IUUC-Mlu-067684	Myotis lucifugus	70.40	0.00e+00	998.00
IUUC-Nle-070057	Nomascus leucogenys	70.31	0.00e+00	1003.00
IUUC-Opr-070463	Ochotona princeps	63.98	0.00e+00	879.00
IUUC-Ont-071975	Oreochromis niloticus	50.66	3.00e-140	492.00
IUUC-Oan-073062	Ornithorhynchus anatinus	70.87	8.00e-38	149.00
IUUC-Ocu-074840	Oryctolagus cuniculus	69.17	0.00e+00	1003.00
IUUC-Ola-087088	Oryzias latipes	48.50	2.00e-165	575.00
IUUC-Oga-088472	Otolemur garnettii	70.31	0.00e+00	990.00
IUUC-Oar-089498	Ovis aries	69.87	0.00e+00	994.00
IUUC-Ptr-091395	Pan troglodytes	70.06	0.00e+00	1004.00
IUUC-Pan-092462	Papio anubis	70.20	0.00e+00	1006.00
IUUC-Psi-093583	Pelodiscus sinensis	77.16	0.00e+00	949.00
IUUC-Pma-094644	Petromyzon marinus	37.76	5.00e-29	120.00
IUUC-Pfo-096314	Poecilia formosa	47.14	4.00e-161	561.00
IUUC-Pab-098568	Pongo abelii	70.06	0.00e+00	1001.00
IUUC-Pca-100948	Procavia capensis	66.50	1.00e-144	506.00
IUUC-Pva-102853	Pteropus vampyrus	70.71	0.00e+00	1003.00
IUUC-Rno-105573	Rattus norvegicus	69.94	0.00e+00	1004.00
IUUC-Sha-107495	Sarcophilus harrisii	68.38	0.00e+00	793.00
IUUC-Sar-113545	Sorex araneus	59.77	0.00e+00	745.00
IUUC-Ssc-115962	Sus scrofa	69.39	0.00e+00	994.00
IUUC-Tru-117893	Takifugu rubripes	46.56	7.00e-153	533.00
IUUC-Tsy-119644	Tarsius syrichta	65.23	1.00e-135	476.00
IUUC-Tni-119819	Tetraodon nigroviridis	47.03	2.00e-163	568.00
IUUC-Tbe-127272	Tupaia belangeri	66.35	0.00e+00	868.00
IUUC-Ttr-128404	Tursiops truncatus	70.20	0.00e+00	991.00
IUUC-Vpa-130205	Vicugna pacos	69.90	0.00e+00	990.00
IUUC-Xtr-132613	Xenopus tropicalis	56.35	0.00e+00	704.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence