iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000035540.7	ENSDART00000147157.2	ENSDARP00000114236.2
ENSDARG00000035540.7	ENSDART00000020434.10	ENSDARP00000027753.10

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.70e-29	99.6	179	216
UBD/Beta-Prp	5.70e-51	174.4	281	536

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH +sv+c+af  + +++ +GsdD+ +k+W ++ g+ll
   Q: 179  GHLSSVYCVAFdRTgRRIFTGSDDCLVKIWATDNGRLL 216
           8**********955599**************9999886 PP

UBD/Beta-Prp

   S: 22   ksllatgsrdgtikvwdvttgkl......lrslsgheae..vtavkfspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvls 99
           +++lat+++dg++  w++ + ++      ++ ++   ++  +++ +fs+ g +l+tg++D++i+v+    + +  ++ l  h+d+v++
   Q: 281  SRFLATTGADGMVCFWQWNSFSMkfvdkpVKFMERSRPGvqISCSSFSSGGLFLATGGTDHMIRVYylGTEMPVKFSDLDSHTDKVVA 368
           689************99999666667776555555555466899**********************44444555677899******** PP
   S: 100  lsfspsg..dklvsGshdrtirvwdletgqclee................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktg 169
           ++f+ ++   ++vsGs+d t+r+w+ +++++ ++                 ++ ++ vv++v+++  ++ ++++  +  +++W++ +g
   Q: 369  IQFCNNTdsLRFVSGSRDGTARIWHYQQQEWKSTvldmttrlpgsavisgDDKSTKLVVTMVAWDRCDRSIITAVSNCLLKVWNSTNG 456
           *****6623579********************99************99977778888999******99******************** PP
   S: 170  kllrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDg 244
           +ll+ l+g h+d v  l+   fds  + l+s+++dg + +wdl++g+ +r + +         v + +fs ++++++++ s+g
   Q: 457  QLLHVLSG-HDDEVFVLEahpFDS--RILLSAGHDGNIYVWDLSKGQKIRNFFNMIegqghGAVFDCKFSVDGQHFACTDSHG 536
           *******9.*********655555..9*********************88887644333334455555555666666666555 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MAAEPCSQIE AELYYLIARF LQSGPCQKSA QMLLQELHEY EIIPKRWSWD GEQFKRSFDD 60
WVLLNQHIPA DYLLRVCKEV GPLIDKHIPP SVPGVHSLLG TGRQSLLRTA KSSSHTLWSG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AACCGCGCGG GGGCGCTCAA ACAAAGCAGC ACGAGCGGCG GCTGCAGGCC GAAACGCTGA 60
GAGCAAATAC AACACAGGCC GCTCTTAGCA AGCAGAGCCC CGTGAACCTC CACCCACCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

KEGG

dre:553209

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001881	Ailuropoda melanoleuca	66.80	0.00e+00	1930.00
IUUC-Apl-004016	Anas platyrhynchos	66.09	0.00e+00	1786.00
IUUC-Aca-004722	Anolis carolinensis	69.84	0.00e+00	1731.00
IUUC-Ame-010602	Astyanax mexicanus	77.30	0.00e+00	2194.00
IUUC-Bta-013198	Bos taurus	66.94	0.00e+00	1748.00
IUUC-Cfa-020963	Canis familiaris	67.13	0.00e+00	1929.00
IUUC-Cpo-022448	Cavia porcellus	63.05	0.00e+00	1791.00
IUUC-Csa-023166	Chlorocebus sabaeus	67.03	0.00e+00	1924.00
IUUC-Dno-030070	Dasypus novemcinctus	65.20	0.00e+00	1842.00
IUUC-Ete-032650	Echinops telfairi	62.83	0.00e+00	1341.00
IUUC-Eca-033953	Equus caballus	67.50	0.00e+00	1711.00
IUUC-Eeu-034871	Erinaceus europaeus	61.37	0.00e+00	974.00
IUUC-Fca-036099	Felis catus	66.74	0.00e+00	1919.00
IUUC-Fal-037246	Ficedula albicollis	69.19	0.00e+00	1880.00
IUUC-Gmo-039116	Gadus morhua	72.52	0.00e+00	631.00
IUUC-Gga-041097	Gallus gallus	69.25	0.00e+00	1933.00
IUUC-Gac-042435	Gasterosteus aculeatus	70.79	0.00e+00	1998.00
IUUC-Hsa-045666	Homo sapiens	66.87	0.00e+00	1928.00
IUUC-Lch-050646	Latimeria chalumnae	58.88	0.00e+00	1712.00
IUUC-Loc-051802	Lepisosteus oculatus	70.70	0.00e+00	2100.00
IUUC-Laf-053942	Loxodonta africana	67.06	0.00e+00	1948.00
IUUC-Mcc-054645	Macaca mulatta	67.10	0.00e+00	1928.00
IUUC-Meu-056321	Macropus eugenii	60.55	0.00e+00	884.00
IUUC-Mtr-058094	Medicago truncatula	31.14	7.00e-71	263.00
IUUC-Mga-060063	Meleagris gallopavo	68.63	0.00e+00	1892.00
IUUC-Mmr-061262	Microcebus murinus	67.13	0.00e+00	1930.00
IUUC-Mdo-062320	Monodelphis domestica	61.19	0.00e+00	1691.00
IUUC-Mmu-063163	Mus musculus	65.32	0.00e+00	1914.00
IUUC-Mpu-066628	Mustela putorius furo	67.03	0.00e+00	1919.00
IUUC-Mlu-068082	Myotis lucifugus	67.08	0.00e+00	1903.00
IUUC-Nle-069609	Nomascus leucogenys	66.99	0.00e+00	1930.00
IUUC-Ont-071589	Oreochromis niloticus	71.26	0.00e+00	2003.00
IUUC-Oan-072954	Ornithorhynchus anatinus	59.67	0.00e+00	1707.00
IUUC-Ocu-074456	Oryctolagus cuniculus	60.28	0.00e+00	1705.00
IUUC-Ogu-078641	Oryza glumaepatula	26.14	2.00e-29	125.00
IUUC-Oin-079669	Oryza indica	32.50	2.00e-50	194.00
IUUC-Olo-080755	Oryza longistaminata	32.43	2.00e-51	198.00
IUUC-Oni-082991	Oryza nivara	26.14	2.00e-29	125.00
IUUC-Ola-086580	Oryzias latipes	70.09	0.00e+00	2045.00
IUUC-Oga-089053	Otolemur garnettii	67.36	0.00e+00	1933.00
IUUC-Oar-090042	Ovis aries	67.26	0.00e+00	1928.00
IUUC-Ptr-091268	Pan troglodytes	66.32	0.00e+00	1892.00
IUUC-Pan-092376	Papio anubis	67.10	0.00e+00	1928.00
IUUC-Psi-093408	Pelodiscus sinensis	65.23	0.00e+00	1884.00
IUUC-Pfo-096515	Poecilia formosa	73.42	0.00e+00	1947.00
IUUC-Pab-097672	Pongo abelii	65.52	0.00e+00	1882.00
IUUC-Pva-102512	Pteropus vampyrus	68.28	0.00e+00	1677.00
IUUC-Rno-105797	Rattus norvegicus	66.57	0.00e+00	1921.00
IUUC-Sha-107061	Sarcophilus harrisii	63.14	0.00e+00	1719.00
IUUC-Sar-113004	Sorex araneus	74.55	0.00e+00	880.00
IUUC-Ssc-115461	Sus scrofa	55.59	0.00e+00	1543.00
IUUC-Tgu-117254	Taeniopygia guttata	68.05	0.00e+00	1866.00
IUUC-Tru-118186	Takifugu rubripes	69.86	0.00e+00	1968.00
IUUC-Tsy-119003	Tarsius syrichta	62.16	0.00e+00	1709.00
IUUC-Tni-120110	Tetraodon nigroviridis	69.00	0.00e+00	1962.00
IUUC-Ttr-129265	Tursiops truncatus	66.60	0.00e+00	1856.00
IUUC-Xtr-132717	Xenopus tropicalis	57.79	0.00e+00	1672.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence