iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nle-069609

Ensembl Protein ID

ENSNLEP00000002950.1

UniProt Accession

G1QPT4; G1QPT4_NOMLE

Genbank Protein ID

ENSNLEP00000002950

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01047485

Gene Name

BRWD3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000002210.1	ENSNLET00000003100.1	ENSNLEP00000002950.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-30	104.3	178	215
UBD/Beta-Prp	1.00e-52	179.2	280	539

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvll 36
           gH +sv+c+af  s++++ +GsdD+ +k+W +++g+ll
   Q: 178  GHLSSVYCVAFdrSGRRIFTGSDDCLVKIWATDDGRLL 215
           8**********96669******************9987 PP

UBD/Beta-Prp

   S: 22   ksllatgsrdgtikvwdvttgkl........lrslsgheae..vtavkfspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvl 98
           +++l+++++dgti  w+++ +++        + + s    +  +++ +fs+ g ++ tgs+D++i+++    + ++ +  l+ h+d+v+
   Q: 280  NRYLTSTGADGTICFWQWHVKTMkfrdrpvkFTERSRP--GvqISCSSFSSGGMFITTGSTDHVIRIYylGSEVPEKIAELESHTDKVV 366
           689*************9998777667776433333333..35599***********************877789*************** PP
   S: 99   slsfspsg..dklvsGshdrtirvwdletgqclee................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktg 169
           +++f+ +g   ++vsGs+d t+r+w+ +++++ +                  +++++  v++v+++  +  ++++ ++  +++W++ tg
   Q: 367  AVQFCNNGdsLRFVSGSRDGTARIWQYQQQEWKSIvldmatkmtannlppgEDKITKLKVTMVAWDRYDTTVITAVNNFLLKVWNSITG 455
           ******8832468*******************999*************99999999999****************************** PP
   S: 170  kllrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiri 248
           +ll+tl+g h+d v  l+   fd+  + ++s+++dg + +wdl +g+ +r + +         v + +fsp++++++++ s+g + +
   Q: 456  QLLHTLSG-HDDEVFVLEahpFDQ--RIILSAGHDGNIFIWDLDRGTKIRNYFNMIegqghGAVFDCKFSPDGNHFACTDSHGHLLL 539
           *******9.*********555555..99********************98887755455567788899999***9999999988766 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MAAAPTQIEA ELYYLIARFL QSGPCNKSAQ VLVQELEEHQ LIPRRLDWEG KEHRRSFEDL 60
VAANAHIPPD YLLKICERIG PLLDKEIPQS VPGVQTLLGV GRQSLLRDAK DCKSTLWNGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTCTCCTCT CTCTCCTTCC TCCTCCGCCT CCTCAGCTCT TGGGCTAGAA TATCTATGGG 60
TCGAAACGTG ATGCGATGAA TTCGAGAGAG AGCGAAACTA GGACGAGGAG TGCGGCGGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001881	Ailuropoda melanoleuca	96.89	0.00e+00	3148.00
IUUC-Apl-004016	Anas platyrhynchos	79.90	0.00e+00	2262.00
IUUC-Aca-004722	Anolis carolinensis	78.04	0.00e+00	2210.00
IUUC-Ame-010602	Astyanax mexicanus	76.10	0.00e+00	1134.00
IUUC-Bta-013198	Bos taurus	95.78	0.00e+00	2872.00
IUUC-Cfa-020963	Canis familiaris	96.78	0.00e+00	3125.00
IUUC-Cpo-022448	Cavia porcellus	89.54	0.00e+00	2862.00
IUUC-Csa-023166	Chlorocebus sabaeus	99.40	0.00e+00	3069.00
IUUC-Cin-025553	Ciona intestinalis	38.83	4.00e-111	395.00
IUUC-Csv-025813	Ciona savignyi	43.62	0.00e+00	642.00
IUUC-Dre-028508	Danio rerio	65.78	0.00e+00	1882.00
IUUC-Dno-030070	Dasypus novemcinctus	93.51	0.00e+00	3017.00
IUUC-Dor-031052	Dipodomys ordii	80.10	0.00e+00	1446.00
IUUC-Dme-031752	Drosophila melanogaster	49.76	0.00e+00	672.00
IUUC-Ete-032650	Echinops telfairi	86.11	0.00e+00	1840.00
IUUC-Eca-033953	Equus caballus	97.12	0.00e+00	2818.00
IUUC-Eeu-034871	Erinaceus europaeus	82.86	0.00e+00	1344.00
IUUC-Fca-036099	Felis catus	96.45	0.00e+00	3151.00
IUUC-Fal-037246	Ficedula albicollis	80.88	0.00e+00	2435.00
IUUC-Gga-041097	Gallus gallus	82.33	0.00e+00	2525.00
IUUC-Gac-042435	Gasterosteus aculeatus	64.93	0.00e+00	1843.00
IUUC-Hsa-045666	Homo sapiens	99.40	0.00e+00	3071.00
IUUC-Loc-051802	Lepisosteus oculatus	69.60	0.00e+00	2065.00
IUUC-Laf-053942	Loxodonta africana	96.08	0.00e+00	3016.00
IUUC-Mcc-054645	Macaca mulatta	99.52	0.00e+00	3074.00
IUUC-Meu-056321	Macropus eugenii	76.13	0.00e+00	1113.00
IUUC-Mga-060063	Meleagris gallopavo	82.98	0.00e+00	2471.00
IUUC-Mmr-061262	Microcebus murinus	96.33	0.00e+00	2997.00
IUUC-Mdo-062320	Monodelphis domestica	75.54	0.00e+00	2300.00
IUUC-Mmu-063163	Mus musculus	94.67	0.00e+00	3043.00
IUUC-Mpu-066628	Mustela putorius furo	96.61	0.00e+00	3159.00
IUUC-Mlu-068082	Myotis lucifugus	96.63	0.00e+00	2968.00
IUUC-Ont-071589	Oreochromis niloticus	66.01	0.00e+00	1812.00
IUUC-Ocu-074122	Oryctolagus cuniculus	94.75	0.00e+00	2133.00
IUUC-Ola-086580	Oryzias latipes	66.14	0.00e+00	1881.00
IUUC-Oga-089053	Otolemur garnettii	95.50	0.00e+00	3101.00
IUUC-Oar-090042	Ovis aries	96.45	0.00e+00	3151.00
IUUC-Ptr-091268	Pan troglodytes	98.49	0.00e+00	3022.00
IUUC-Pan-092376	Papio anubis	99.46	0.00e+00	3073.00
IUUC-Psi-093408	Pelodiscus sinensis	81.20	0.00e+00	2529.00
IUUC-Pfo-096515	Poecilia formosa	64.89	0.00e+00	1785.00
IUUC-Pab-097672	Pongo abelii	97.41	0.00e+00	3027.00
IUUC-Pva-102512	Pteropus vampyrus	97.58	0.00e+00	2357.00
IUUC-Rno-105797	Rattus norvegicus	94.21	0.00e+00	2922.00
IUUC-Sha-107061	Sarcophilus harrisii	76.47	0.00e+00	2306.00
IUUC-Sit-110017	Setaria italica	29.00	2.00e-56	215.00
IUUC-Sar-113004	Sorex araneus	84.48	0.00e+00	1669.00
IUUC-Tgu-117254	Taeniopygia guttata	81.81	0.00e+00	2430.00
IUUC-Tru-118186	Takifugu rubripes	65.33	0.00e+00	1834.00
IUUC-Tsy-119003	Tarsius syrichta	90.34	0.00e+00	2727.00
IUUC-Tni-120110	Tetraodon nigroviridis	65.04	0.00e+00	1801.00
IUUC-Tbe-127813	Tupaia belangeri	78.50	0.00e+00	939.00
IUUC-Ttr-129265	Tursiops truncatus	93.01	0.00e+00	2852.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence