iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000004457.1	ENSONIT00000005615.1	ENSONIP00000005611.1
ENSONIG00000004457.1	ENSONIT00000005616.1	ENSONIP00000005612.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.00e-29	100.8	179	216
UBD/Beta-Prp	5.40e-65	219.9	180	399

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH +sv+c+af  + +++ +GsdD+ +k+W +++g+ll
   Q: 179  GHLSSVYCVAFdRTgRRIFTGSDDCLVKIWATDDGRLL 216
           8**********955599*****************9987 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsv 97
           h s ++cv+f + ++ ++tgs+d  +k+w +++g ll++l gh+ae+ ++  +++ ++++++s D++i+vw l+++ ++ +l++h +s+
   Q: 180  HLSSVYCVAFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEICDMAVNHENSLIASASCDKVIRVWCLRACAPITVLQAHAASI 268
           5567889********************************************************************************** PP
   S: 98   lslsfsp....sgdklvsGshdrtirvwdletgqclee......tlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtl 175
           +s++f+p    ++ +l+s+++d ++  w++++ +   +      +++ + gv  ++++ ++g   +++G++D ++r++ l  ++ ++  
   Q: 269  TSIQFCPaargTTRYLASTGADGMVCFWKWHSLTMKFNdqpvkfMERSRPGVQVSTSSFSSGgMFMATGGTDHMIRVYYLGAESPMKVS 357
           *********9999******************98876666999999999999887777777776999**************666666655 PP
   S: 176  ..tgghtdsvyslsfdsng..kelvsgsldgtvklwdlqtgec 214
                htd+v  ++f+ n+   ++vsgs+dgtvk+w +q++e 
   Q: 358  emDA-HTDKVVVVQFSNNSdsLRFVSGSRDGTVKIWHYQQQEW 399
           4265.***********99988899***************7654 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MAREQCSQIE AELYYLIARF LQSGPCKKAA KILIEELEEY ELVPQRWSWD GKKYKRNFQD 60
WVVVNQHIPA DYLLRICQRI GPLIEKEIPP SVPGVQTLLG LGRQSLLRTS KSCSHKVCSG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATTGCAACT GTATATTGAC TGGCAACAAT ATATTTAAAA CCACAAATAT TTTTATTCAC 60
AAAATAGCAT TGTTGCCCCC CCCCCCCAAA AAAAAAAAAA ATAAATTACG AATACATTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR002469--Peptidase_S9B_N
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001881	Ailuropoda melanoleuca	66.55	0.00e+00	1920.00
IUUC-Apl-004016	Anas platyrhynchos	64.88	0.00e+00	1790.00
IUUC-Aca-004722	Anolis carolinensis	65.16	0.00e+00	1723.00
IUUC-Ame-010602	Astyanax mexicanus	74.85	0.00e+00	2021.00
IUUC-Bta-013198	Bos taurus	66.41	0.00e+00	1762.00
IUUC-Cfa-020963	Canis familiaris	66.55	0.00e+00	1920.00
IUUC-Cpo-022448	Cavia porcellus	62.69	0.00e+00	1801.00
IUUC-Csa-023166	Chlorocebus sabaeus	66.60	0.00e+00	1922.00
IUUC-Cin-025553	Ciona intestinalis	40.00	7.00e-112	398.00
IUUC-Dre-028508	Danio rerio	68.79	0.00e+00	2081.00
IUUC-Dno-030070	Dasypus novemcinctus	64.52	0.00e+00	1843.00
IUUC-Ete-032650	Echinops telfairi	61.59	0.00e+00	1301.00
IUUC-Eca-033953	Equus caballus	66.85	0.00e+00	1728.00
IUUC-Eeu-034871	Erinaceus europaeus	59.80	0.00e+00	941.00
IUUC-Fca-036099	Felis catus	66.26	0.00e+00	1916.00
IUUC-Fal-037246	Ficedula albicollis	65.29	0.00e+00	1885.00
IUUC-Gmo-039116	Gadus morhua	77.27	0.00e+00	687.00
IUUC-Gga-041097	Gallus gallus	65.13	0.00e+00	1932.00
IUUC-Gac-042435	Gasterosteus aculeatus	80.47	0.00e+00	2401.00
IUUC-Hsa-045666	Homo sapiens	66.67	0.00e+00	1927.00
IUUC-Lch-050646	Latimeria chalumnae	56.04	0.00e+00	1688.00
IUUC-Loc-051802	Lepisosteus oculatus	70.83	0.00e+00	2123.00
IUUC-Laf-053942	Loxodonta africana	66.83	0.00e+00	1942.00
IUUC-Mcc-054645	Macaca mulatta	66.67	0.00e+00	1926.00
IUUC-Meu-056321	Macropus eugenii	60.22	0.00e+00	878.00
IUUC-Mga-060063	Meleagris gallopavo	64.52	0.00e+00	1896.00
IUUC-Mmr-061262	Microcebus murinus	66.07	0.00e+00	1937.00
IUUC-Mdo-062320	Monodelphis domestica	62.15	0.00e+00	1758.00
IUUC-Mmu-063163	Mus musculus	66.28	0.00e+00	1916.00
IUUC-Mpu-066628	Mustela putorius furo	66.41	0.00e+00	1911.00
IUUC-Mlu-068082	Myotis lucifugus	66.71	0.00e+00	1894.00
IUUC-Nle-069609	Nomascus leucogenys	66.39	0.00e+00	1927.00
IUUC-Oan-072954	Ornithorhynchus anatinus	58.28	0.00e+00	1665.00
IUUC-Ogu-078641	Oryza glumaepatula	28.94	1.00e-38	156.00
IUUC-Oni-082991	Oryza nivara	28.94	2.00e-40	162.00
IUUC-Ola-086580	Oryzias latipes	79.23	0.00e+00	2444.00
IUUC-Oga-089053	Otolemur garnettii	63.98	0.00e+00	1928.00
IUUC-Oar-090042	Ovis aries	66.55	0.00e+00	1922.00
IUUC-Ptr-091268	Pan troglodytes	66.05	0.00e+00	1890.00
IUUC-Pan-092376	Papio anubis	66.67	0.00e+00	1926.00
IUUC-Psi-093408	Pelodiscus sinensis	64.64	0.00e+00	1911.00
IUUC-Pfo-096515	Poecilia formosa	81.38	0.00e+00	2354.00
IUUC-Pab-097672	Pongo abelii	65.23	0.00e+00	1887.00
IUUC-Pva-102512	Pteropus vampyrus	68.69	0.00e+00	1675.00
IUUC-Rno-105797	Rattus norvegicus	66.69	0.00e+00	1922.00
IUUC-Sha-107061	Sarcophilus harrisii	63.59	0.00e+00	1765.00
IUUC-Sar-113004	Sorex araneus	73.39	0.00e+00	848.00
IUUC-Tgu-117254	Taeniopygia guttata	64.19	0.00e+00	1871.00
IUUC-Tru-118186	Takifugu rubripes	81.95	0.00e+00	2382.00
IUUC-Tsy-119003	Tarsius syrichta	61.28	0.00e+00	1712.00
IUUC-Tni-120110	Tetraodon nigroviridis	79.39	0.00e+00	2378.00
IUUC-Ttr-129265	Tursiops truncatus	66.13	0.00e+00	1875.00
IUUC-Vpa-130160	Vicugna pacos	57.29	0.00e+00	1583.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence