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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046933
UUCD1 version UUC-HoS-01173
Ensembl Protein ID ENSP00000299413.5
UniProt Accession Q96DX7; D3DR14; Q96QY2; Q9UGK0; TRI44_HUMAN
Genbank Protein ID CAB65108.1; EAW68133.1; EAW68134.1; AAH13166.1; AAH24031.1
Protein Name Tripartite motif-containing protein 44; Protein DIPB
Genbank Nucleotide ID AJ249128; AL138812; CH471064; BC013166; BC024031
Gene Name TRIM44; DIPB
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000166326.6 ENST00000299413.6 ENSP00000299413.5
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBasecircRNADb
CircNetmiRTarBasemicroRNATRANSFAC
TargetScanRepTarSomamiRmiRcode
RAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
MenthaInWeb_IM
Disease-associated Information
ClinVarGWASdbOMIM
Post-translational Modifications (PTMs)
CPLMdbPAFPhosSNPPhosphositePlus
dbPTMHPRDBioGRIDmUbiSiDa
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
DUB/Other DUB/Other 19358823
Organism Homo sapiens
Functional Description
(View)

Functional Description


     May play a role in the process of differentiation and maturation of neuronal cells (By similarity). May regulate the activity of TRIM17. Is a negative regulator of PAX6 expression (PubMed:26394807).
 May play a role in the process of differentiation and maturation of neuronal cells (By similarity). May regulate the activity of TRIM17. Is a negative regulator of PAX6 expression (PubMed:26394807).
Protein Sequence
(Fasta)
MASGVGAAFE ELPHDGTCDE CEPDEAPGAE EVCRECGFCY CRRHAEAHRQ KFLSHHLAEY 60
VHGSQAWTPP ADGEGAGKEE AEVKVEQERE IESEAGEESE SEEESESEEE SETEEESEDE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046933|DUB,DUB/Other|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGAGGCTGAG CGGGCGGCGC GACGCGGGGG CCGACGGGGG CGCCGGGTGG CCGCGCCGGA 60
AGTGCCTTGC GCGGCAGAGG AAGCGCAGGG ACAGAGCGGA GCAGGCCGAG CCGGCGGAAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046933|DUB,DUB/Other|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0225--Disease mutation
KW-0479--Metal-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR000315--Znf_B-box
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50119--ZF_BBOX
Pfam

PF00643--zf-B_box
SMART

SM00336--BBOX
Gene Ontology

GO:0005622--C:intracellular
GO:0008270--F:zinc ion binding
GO:0010468--P:regulation of gene expression
KEGG hsa:54765
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002135 Ailuropoda melanoleuca 92.78 2.00e-93 335.00
IUUC-Atr-002531 Amborella trichopoda 37.14 2.80e-02 31.60
IUUC-Aca-004299 Anolis carolinensis 51.20 7.00e-43 166.00
IUUC-Aor-010081 Aspergillus oryzae 31.67 1.70e-01 29.60
IUUC-Ame-011462 Astyanax mexicanus 34.03 6.00e-24 104.00
IUUC-Bta-012387 Bos taurus 98.19 5.00e-91 327.00
IUUC-Bol-016106 Brassica oleracea 28.57 2.70e-02 30.00
IUUC-Cja-019460 Callithrix jacchus 100.00 1.00e-101 362.00
IUUC-Cfa-020100 Canis familiaris 98.90 9.00e-101 360.00
IUUC-Cpo-021464 Cavia porcellus 96.15 6.00e-99 353.00
IUUC-Csa-024181 Chlorocebus sabaeus 99.45 1.00e-100 360.00
IUUC-Cho-024604 Choloepus hoffmanni 98.35 2.00e-62 233.00
IUUC-Dre-028806 Danio rerio 36.99 1.00e-25 110.00
IUUC-Dno-029318 Dasypus novemcinctus 98.20 5.00e-92 331.00
IUUC-Dor-030588 Dipodomys ordii 99.45 4.00e-101 361.00
IUUC-Ete-032249 Echinops telfairi 98.85 1.00e-46 179.00
IUUC-Eca-034032 Equus caballus 82.42 2.00e-81 295.00
IUUC-Eeu-035183 Erinaceus europaeus 97.11 1.00e-96 345.00
IUUC-Fca-035500 Felis catus 96.51 1.00e-92 332.00
IUUC-Gmo-038768 Gadus morhua 28.47 8.00e-12 63.20
IUUC-Gac-041906 Gasterosteus aculeatus 32.64 2.00e-22 99.80
IUUC-Ggo-044418 Gorilla gorilla 100.00 9.00e-97 346.00
IUUC-Itr-048650 Ictidomys tridecemlineatus 99.45 3.00e-101 362.00
IUUC-Lch-050015 Latimeria chalumnae 51.45 4.00e-49 187.00
IUUC-Loc-052380 Lepisosteus oculatus 33.33 2.00e-24 105.00
IUUC-Laf-053357 Loxodonta africana 98.88 1.00e-47 183.00
IUUC-Mcc-055177 Macaca mulatta 100.00 1.00e-101 362.00
IUUC-Meu-056827 Macropus eugenii 58.75 1.00e-21 97.40
IUUC-Mmr-061691 Microcebus murinus 99.45 3.00e-101 361.00
IUUC-Mdo-062692 Monodelphis domestica 55.49 2.00e-49 189.00
IUUC-Mmu-064220 Mus musculus 98.90 2.00e-100 359.00
IUUC-Mac-065055 Musa acuminata 25.66 1.70e-02 34.30
IUUC-Mpu-066428 Mustela putorius furo 98.35 2.00e-100 358.00
IUUC-Mlu-068019 Myotis lucifugus 96.86 1.00e-87 316.00
IUUC-Nle-069471 Nomascus leucogenys 100.00 2.00e-101 362.00
IUUC-Opr-070285 Ochotona princeps 97.70 8.00e-46 177.00
IUUC-Ont-071942 Oreochromis niloticus 32.88 5.00e-20 91.70
IUUC-Oan-073022 Ornithorhynchus anatinus 56.77 4.00e-50 191.00
IUUC-Ocu-074814 Oryctolagus cuniculus 98.90 5.00e-101 360.00
IUUC-Oga-088155 Otolemur garnettii 98.82 1.00e-93 336.00
IUUC-Oar-090128 Ovis aries 97.48 7.00e-87 313.00
IUUC-Ptr-091061 Pan troglodytes 100.00 1.00e-101 363.00
IUUC-Pan-091763 Papio anubis 100.00 1.00e-101 363.00
IUUC-Pfo-097020 Poecilia formosa 37.93 7.00e-07 48.10
IUUC-Pab-098411 Pongo abelii 100.00 1.00e-101 362.00
IUUC-Pca-100887 Procavia capensis 95.76 3.00e-85 308.00
IUUC-Rno-105053 Rattus norvegicus 98.84 1.00e-95 343.00
IUUC-Ssc-115541 Sus scrofa 97.58 2.00e-89 322.00
IUUC-Tru-118513 Takifugu rubripes 32.64 7.00e-22 97.80
IUUC-Tsy-118871 Tarsius syrichta 70.88 5.00e-62 230.00
IUUC-Tni-120386 Tetraodon nigroviridis 31.94 2.00e-18 85.50
IUUC-Ttr-128801 Tursiops truncatus 98.85 3.00e-46 179.00
IUUC-Xtr-132484 Xenopus tropicalis 43.75 3.00e-39 155.00
Created Date 25-Jun-2017

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