iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-059636

Ensembl Protein ID

ENSMGAP00000013731.2

UniProt Accession

G1NK21; G1NK21_MELGA

Protein Name

Uncharacterized protein

Gene Name

MAP3K5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000013015.2	ENSMGAT00000014646.2	ENSMGAP00000013731.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UDP/UBQ/UBQ_Other	88.61	0.00e+00	2138.00	IUUC-Hsa-046906

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

FLSTDIAVVE MSDAFRQPSL FYHLGVRESF SMANNIILYC DTNSESLQSL KEIICQKNNM 60
CTGNYIFVPY MITPHNKVYC CDSSFMKGLT ELMQPSFESL LGPICLPLVD RFIQLLKVAQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTCTTTCTA CAGATATTGC TGTTGTAGAG ATGAGTGATG CCTTTCGTCA GCCTTCCCTC 60
TTCTACCACC TGGGAGTCAG AGAGAGCTTC AGTATGGCTA ACAACATTAT CCTCTACTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR025136--DUF4071
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR013761--SAM/pointed
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF13281--DUF4071
PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:1990604--C:IRE1-TRAF2-ASK1 complex
GO:1902911--C:protein kinase complex
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004709--F:MAP kinase kinase kinase activity
GO:0000187--P:activation of MAPK activity
GO:0070301--P:cellular response to hydrogen peroxide
GO:1902170--P:cellular response to reactive nitrogen species
GO:0070059--P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0008631--P:intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0007254--P:JNK cascade
GO:0038066--P:p38MAPK cascade
GO:0043280--P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043507--P:positive regulation of JUN kinase activity
GO:0045663--P:positive regulation of myoblast differentiation
GO:1901216--P:positive regulation of neuron death
GO:0097300--P:programmed necrotic cell death

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002318	Ailuropoda melanoleuca	88.60	0.00e+00	2056.00
IUUC-Apl-003713	Anas platyrhynchos	98.51	0.00e+00	2253.00
IUUC-Aca-005331	Anolis carolinensis	89.14	0.00e+00	2083.00
IUUC-Ame-011158	Astyanax mexicanus	75.69	0.00e+00	1762.00
IUUC-Bta-012770	Bos taurus	88.85	0.00e+00	2147.00
IUUC-Cja-019656	Callithrix jacchus	88.28	0.00e+00	2127.00
IUUC-Cfa-020488	Canis familiaris	88.20	0.00e+00	2130.00
IUUC-Cpo-022516	Cavia porcellus	87.29	0.00e+00	2043.00
IUUC-Csa-023104	Chlorocebus sabaeus	88.76	0.00e+00	2131.00
IUUC-Cho-024379	Choloepus hoffmanni	84.38	0.00e+00	1171.00
IUUC-Dre-028836	Danio rerio	75.55	0.00e+00	1802.00
IUUC-Dno-029842	Dasypus novemcinctus	86.80	0.00e+00	2059.00
IUUC-Dor-030990	Dipodomys ordii	89.24	0.00e+00	1828.00
IUUC-Ete-032693	Echinops telfairi	79.15	0.00e+00	1696.00
IUUC-Eca-033337	Equus caballus	88.12	0.00e+00	2144.00
IUUC-Eeu-034602	Erinaceus europaeus	73.51	0.00e+00	1675.00
IUUC-Fca-035954	Felis catus	87.73	0.00e+00	1794.00
IUUC-Fal-037358	Ficedula albicollis	96.08	0.00e+00	2274.00
IUUC-Gmo-038836	Gadus morhua	80.44	0.00e+00	1650.00
IUUC-Gga-040443	Gallus gallus	99.51	0.00e+00	2359.00
IUUC-Gac-041634	Gasterosteus aculeatus	77.24	0.00e+00	1842.00
IUUC-Ggo-045263	Gorilla gorilla	86.46	0.00e+00	2063.00
IUUC-Hsa-046906	Homo sapiens	88.61	0.00e+00	2145.00
IUUC-Itr-048449	Ictidomys tridecemlineatus	87.14	0.00e+00	1018.00
IUUC-Lch-050213	Latimeria chalumnae	79.90	0.00e+00	1798.00
IUUC-Loc-051829	Lepisosteus oculatus	76.24	0.00e+00	1785.00
IUUC-Laf-053538	Loxodonta africana	88.59	0.00e+00	2130.00
IUUC-Mcc-054776	Macaca mulatta	88.61	0.00e+00	2142.00
IUUC-Mmr-061323	Microcebus murinus	88.54	0.00e+00	2101.00
IUUC-Mdo-062146	Monodelphis domestica	89.17	0.00e+00	2083.00
IUUC-Mmu-064022	Mus musculus	88.02	0.00e+00	2113.00
IUUC-Mpu-066531	Mustela putorius furo	86.74	0.00e+00	2131.00
IUUC-Mlu-068181	Myotis lucifugus	86.48	0.00e+00	2105.00
IUUC-Nle-069758	Nomascus leucogenys	88.76	0.00e+00	2133.00
IUUC-Opr-070531	Ochotona princeps	81.80	0.00e+00	1379.00
IUUC-Ont-072014	Oreochromis niloticus	78.50	0.00e+00	1818.00
IUUC-Oan-073169	Ornithorhynchus anatinus	89.24	0.00e+00	2148.00
IUUC-Ocu-074050	Oryctolagus cuniculus	84.57	0.00e+00	2007.00
IUUC-Ola-086941	Oryzias latipes	80.70	0.00e+00	1529.00
IUUC-Oga-088796	Otolemur garnettii	87.95	0.00e+00	2093.00
IUUC-Oar-090445	Ovis aries	89.30	0.00e+00	2147.00
IUUC-Ptr-090846	Pan troglodytes	88.69	0.00e+00	2147.00
IUUC-Pan-091986	Papio anubis	88.61	0.00e+00	2142.00
IUUC-Psi-093805	Pelodiscus sinensis	91.88	0.00e+00	2281.00
IUUC-Pfo-097301	Poecilia formosa	78.68	0.00e+00	1838.00
IUUC-Pab-097662	Pongo abelii	88.53	0.00e+00	2145.00
IUUC-Pca-100755	Procavia capensis	66.41	0.00e+00	657.00
IUUC-Pva-102280	Pteropus vampyrus	79.98	0.00e+00	1859.00
IUUC-Rno-105547	Rattus norvegicus	87.45	0.00e+00	2102.00
IUUC-Sha-106859	Sarcophilus harrisii	89.32	0.00e+00	2053.00
IUUC-Sar-113714	Sorex araneus	77.33	0.00e+00	1788.00
IUUC-Tgu-117116	Taeniopygia guttata	94.63	0.00e+00	2241.00
IUUC-Tru-118088	Takifugu rubripes	78.47	0.00e+00	1877.00
IUUC-Tsy-119616	Tarsius syrichta	84.70	0.00e+00	1736.00
IUUC-Tni-120284	Tetraodon nigroviridis	76.53	0.00e+00	1831.00
IUUC-Tbe-127900	Tupaia belangeri	89.36	0.00e+00	814.00
IUUC-Ttr-128294	Tursiops truncatus	77.38	0.00e+00	1805.00
IUUC-Vpa-130470	Vicugna pacos	79.58	0.00e+00	1861.00
IUUC-Xtr-132396	Xenopus tropicalis	79.82	0.00e+00	1855.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence