iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-074050

Ensembl Protein ID

ENSOCUP00000013271.3

UniProt Accession

G1T9G5; G1T9G5_RABIT

Genbank Protein ID

ENSOCUP00000013271

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02028665

Gene Name

MAP3K5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000015434.3	ENSOCUT00000015446.3	ENSOCUP00000013271.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UDP/UBQ/UBQ_Other	92.65	0.00e+00	2169.00	IUUC-Hsa-046906

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MSDAFRQPSL FYHLGVRESF SMANNIILYC DSNADSLQSL KEIICQKNTM CTGNYTFVPY 60
MVTPHNKVYC CDSSLMKGLT ELMQPNLELL LGPICLPLVD RFIRLLKVAQ ASSSQYFRES 120

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Nucleotide Sequence
(Fasta)

ACATTGCTGT GGTGGAGATG AGCGATGCCT TCCGGCAGCC CTCCTTGTTC TACCACCTTG 60
GGGTGAGAGA GAGCTTCAGC ATGGCCAACA ACATCATCCT CTACTGTGAC AGCAACGCAG 120

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Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR025136--DUF4071
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR013761--SAM/pointed
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF13281--DUF4071
PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:1990604--C:IRE1-TRAF2-ASK1 complex
GO:1902911--C:protein kinase complex
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004709--F:MAP kinase kinase kinase activity
GO:0000187--P:activation of MAPK activity
GO:0070301--P:cellular response to hydrogen peroxide
GO:1902170--P:cellular response to reactive nitrogen species
GO:0070059--P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0008631--P:intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0007254--P:JNK cascade
GO:0038066--P:p38MAPK cascade
GO:0043280--P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043507--P:positive regulation of JUN kinase activity
GO:0045663--P:positive regulation of myoblast differentiation
GO:1901216--P:positive regulation of neuron death
GO:0097300--P:programmed necrotic cell death

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002318	Ailuropoda melanoleuca	92.20	0.00e+00	2075.00
IUUC-Apl-003713	Anas platyrhynchos	85.16	0.00e+00	1948.00
IUUC-Aca-005331	Anolis carolinensis	83.60	0.00e+00	1966.00
IUUC-Ame-011158	Astyanax mexicanus	72.94	0.00e+00	1673.00
IUUC-Bta-012770	Bos taurus	91.51	0.00e+00	2152.00
IUUC-Cja-019656	Callithrix jacchus	92.24	0.00e+00	2163.00
IUUC-Cfa-020488	Canis familiaris	91.49	0.00e+00	2144.00
IUUC-Cpo-022516	Cavia porcellus	90.76	0.00e+00	2056.00
IUUC-Csa-023104	Chlorocebus sabaeus	92.57	0.00e+00	2180.00
IUUC-Cho-024379	Choloepus hoffmanni	89.47	0.00e+00	1228.00
IUUC-Dre-028836	Danio rerio	72.38	0.00e+00	1693.00
IUUC-Dno-029842	Dasypus novemcinctus	89.37	0.00e+00	2063.00
IUUC-Dor-030990	Dipodomys ordii	90.61	0.00e+00	1812.00
IUUC-Ete-032693	Echinops telfairi	81.14	0.00e+00	1684.00
IUUC-Eca-033337	Equus caballus	91.02	0.00e+00	2174.00
IUUC-Eeu-034602	Erinaceus europaeus	75.43	0.00e+00	1705.00
IUUC-Fca-035954	Felis catus	90.63	0.00e+00	1803.00
IUUC-Fal-037358	Ficedula albicollis	84.98	0.00e+00	1990.00
IUUC-Gmo-038836	Gadus morhua	77.36	0.00e+00	1581.00
IUUC-Gga-040443	Gallus gallus	84.73	0.00e+00	2004.00
IUUC-Gac-041634	Gasterosteus aculeatus	74.27	0.00e+00	1769.00
IUUC-Ggo-045263	Gorilla gorilla	90.80	0.00e+00	2103.00
IUUC-Hsa-046906	Homo sapiens	92.57	0.00e+00	2173.00
IUUC-Itr-048449	Ictidomys tridecemlineatus	95.02	0.00e+00	1110.00
IUUC-Lch-050213	Latimeria chalumnae	75.74	0.00e+00	1719.00
IUUC-Loc-051829	Lepisosteus oculatus	72.34	0.00e+00	1697.00
IUUC-Laf-053538	Loxodonta africana	91.99	0.00e+00	2152.00
IUUC-Mcc-054776	Macaca mulatta	92.49	0.00e+00	2177.00
IUUC-Mga-059636	Meleagris gallopavo	84.65	0.00e+00	2003.00
IUUC-Mmr-061323	Microcebus murinus	92.41	0.00e+00	2129.00
IUUC-Mdo-062146	Monodelphis domestica	90.03	0.00e+00	2058.00
IUUC-Mmu-064022	Mus musculus	91.82	0.00e+00	2134.00
IUUC-Mpu-066531	Mustela putorius furo	88.88	0.00e+00	2138.00
IUUC-Mlu-068181	Myotis lucifugus	89.71	0.00e+00	2120.00
IUUC-Nle-069758	Nomascus leucogenys	92.65	0.00e+00	2178.00
IUUC-Opr-070531	Ochotona princeps	83.73	0.00e+00	1379.00
IUUC-Ont-072014	Oreochromis niloticus	74.43	0.00e+00	1727.00
IUUC-Oan-073169	Ornithorhynchus anatinus	88.48	0.00e+00	2099.00
IUUC-Ola-086941	Oryzias latipes	76.19	0.00e+00	1448.00
IUUC-Oga-088796	Otolemur garnettii	91.76	0.00e+00	2131.00
IUUC-Oar-090445	Ovis aries	91.76	0.00e+00	2155.00
IUUC-Ptr-090846	Pan troglodytes	92.65	0.00e+00	2178.00
IUUC-Pan-091986	Papio anubis	92.57	0.00e+00	2180.00
IUUC-Psi-093805	Pelodiscus sinensis	85.28	0.00e+00	2113.00
IUUC-Pfo-097301	Poecilia formosa	74.16	0.00e+00	1731.00
IUUC-Pab-097662	Pongo abelii	92.49	0.00e+00	2175.00
IUUC-Pca-100755	Procavia capensis	93.24	0.00e+00	713.00
IUUC-Pva-102280	Pteropus vampyrus	82.69	0.00e+00	1895.00
IUUC-Rno-105547	Rattus norvegicus	90.27	0.00e+00	2121.00
IUUC-Sha-106859	Sarcophilus harrisii	89.94	0.00e+00	2031.00
IUUC-Sar-113714	Sorex araneus	80.83	0.00e+00	1828.00
IUUC-Tgu-117116	Taeniopygia guttata	83.36	0.00e+00	1949.00
IUUC-Tru-118088	Takifugu rubripes	73.47	0.00e+00	1762.00
IUUC-Tsy-119616	Tarsius syrichta	86.74	0.00e+00	1721.00
IUUC-Tni-120284	Tetraodon nigroviridis	72.78	0.00e+00	1742.00
IUUC-Tbe-127900	Tupaia belangeri	94.90	0.00e+00	852.00
IUUC-Ttr-128294	Tursiops truncatus	80.49	0.00e+00	1822.00
IUUC-Vpa-130470	Vicugna pacos	82.69	0.00e+00	1875.00
IUUC-Xtr-132396	Xenopus tropicalis	74.88	0.00e+00	1760.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence