iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000031700.6	ENSRNOT00000051496.6	ENSRNOP00000051338.5
ENSRNOG00000031700.6	ENSRNOT00000067070.3	ENSRNOP00000063417.3

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
ArrayExpress
DNA & RNA Element
TRANSFAC
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UDP/UBQ/UBQ_Other	92.89	0.00e+00	2414.00	IUUC-Hsa-046906

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MGTEAGEGIT FSVPPILSAG FCPIPEGGSC RRGGGAATAA EGEPSLQPLL MPPPPPPPGS 60
FWNVESAAAP GTSCPTTAPG SSATRGRGNS GSGGGRRTTV AYVINEASQG QLVVAESEAL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGCACCG AAGCCGGCGA GGGCATCACT TTCTCCGTGC CGCCCATTTT GTCCGCGGGT 60
TTCTGCCCCA TCCCGGAGGG CGGCAGCTGC CGGAGGGGAG GAGGAGCGGC GACGGCGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR025136--DUF4071
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR013761--SAM/pointed
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF13281--DUF4071
PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0009897--C:external side of plasma membrane
GO:1990604--C:IRE1-TRAF2-ASK1 complex
GO:1902911--C:protein kinase complex
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004709--F:MAP kinase kinase kinase activity
GO:0000187--P:activation of MAPK activity
GO:0070301--P:cellular response to hydrogen peroxide
GO:1902170--P:cellular response to reactive nitrogen species
GO:0071356--P:cellular response to tumor necrosis factor
GO:0072577--P:endothelial cell apoptotic process
GO:0070059--P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0008631--P:intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0007254--P:JNK cascade
GO:0038066--P:p38MAPK cascade
GO:0010666--P:positive regulation of cardiac muscle cell apoptotic process
GO:0043280--P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043507--P:positive regulation of JUN kinase activity
GO:0045663--P:positive regulation of myoblast differentiation
GO:1901216--P:positive regulation of neuron death
GO:1900745--P:positive regulation of p38MAPK cascade
GO:0001934--P:positive regulation of protein phosphorylation
GO:1904707--P:positive regulation of vascular smooth muscle cell proliferation
GO:0097300--P:programmed necrotic cell death
GO:0034976--P:response to endoplasmic reticulum stress
GO:0002931--P:response to ischemia
GO:0042060--P:wound healing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002318	Ailuropoda melanoleuca	94.13	0.00e+00	2272.00
IUUC-Apl-003713	Anas platyrhynchos	87.67	0.00e+00	2051.00
IUUC-Aca-005331	Anolis carolinensis	86.50	0.00e+00	2039.00
IUUC-Ame-011158	Astyanax mexicanus	74.86	0.00e+00	1824.00
IUUC-Bta-012770	Bos taurus	91.88	0.00e+00	2370.00
IUUC-Cja-019656	Callithrix jacchus	92.39	0.00e+00	2409.00
IUUC-Cfa-020488	Canis familiaris	91.80	0.00e+00	2373.00
IUUC-Cpo-022516	Cavia porcellus	93.26	0.00e+00	2272.00
IUUC-Csa-023104	Chlorocebus sabaeus	95.40	0.00e+00	2253.00
IUUC-Cho-024379	Choloepus hoffmanni	87.32	0.00e+00	1185.00
IUUC-Dre-028836	Danio rerio	74.03	0.00e+00	1849.00
IUUC-Dno-029842	Dasypus novemcinctus	91.52	0.00e+00	2149.00
IUUC-Dor-030990	Dipodomys ordii	93.64	0.00e+00	1892.00
IUUC-Ete-032693	Echinops telfairi	81.90	0.00e+00	1920.00
IUUC-Eca-033337	Equus caballus	93.32	0.00e+00	2258.00
IUUC-Eeu-034602	Erinaceus europaeus	77.37	0.00e+00	1946.00
IUUC-Fca-035954	Felis catus	93.61	0.00e+00	1870.00
IUUC-Fal-037358	Ficedula albicollis	87.16	0.00e+00	2075.00
IUUC-Gmo-038836	Gadus morhua	77.89	0.00e+00	1740.00
IUUC-Gga-040443	Gallus gallus	87.66	0.00e+00	2204.00
IUUC-Gac-041634	Gasterosteus aculeatus	74.96	0.00e+00	1916.00
IUUC-Ggo-045263	Gorilla gorilla	90.96	0.00e+00	2345.00
IUUC-Hsa-046906	Homo sapiens	92.89	0.00e+00	2426.00
IUUC-Itr-048449	Ictidomys tridecemlineatus	94.03	0.00e+00	1094.00
IUUC-Lch-050213	Latimeria chalumnae	78.04	0.00e+00	1783.00
IUUC-Loc-051829	Lepisosteus oculatus	75.64	0.00e+00	1848.00
IUUC-Laf-053538	Loxodonta africana	92.17	0.00e+00	2411.00
IUUC-Mcc-054776	Macaca mulatta	93.26	0.00e+00	2441.00
IUUC-Mga-059636	Meleagris gallopavo	87.45	0.00e+00	2106.00
IUUC-Mmr-061323	Microcebus murinus	92.75	0.00e+00	2367.00
IUUC-Mdo-062146	Monodelphis domestica	89.05	0.00e+00	2282.00
IUUC-Mmu-064022	Mus musculus	96.81	0.00e+00	2449.00
IUUC-Mpu-066531	Mustela putorius furo	89.66	0.00e+00	2365.00
IUUC-Mlu-068181	Myotis lucifugus	88.03	0.00e+00	2333.00
IUUC-Nle-069758	Nomascus leucogenys	95.23	0.00e+00	2248.00
IUUC-Opr-070531	Ochotona princeps	87.33	0.00e+00	1452.00
IUUC-Ont-072014	Oreochromis niloticus	77.10	0.00e+00	1891.00
IUUC-Oan-073169	Ornithorhynchus anatinus	91.76	0.00e+00	2197.00
IUUC-Ocu-074050	Oryctolagus cuniculus	90.35	0.00e+00	2116.00
IUUC-Ola-086941	Oryzias latipes	79.81	0.00e+00	1538.00
IUUC-Oga-088796	Otolemur garnettii	92.17	0.00e+00	2360.00
IUUC-Oar-090445	Ovis aries	94.60	0.00e+00	2243.00
IUUC-Ptr-090846	Pan troglodytes	92.82	0.00e+00	2429.00
IUUC-Pan-091986	Papio anubis	93.18	0.00e+00	2437.00
IUUC-Psi-093805	Pelodiscus sinensis	87.26	0.00e+00	2192.00
IUUC-Pfo-097301	Poecilia formosa	75.86	0.00e+00	1899.00
IUUC-Pab-097662	Pongo abelii	94.47	0.00e+00	2383.00
IUUC-Pca-100755	Procavia capensis	92.48	0.00e+00	708.00
IUUC-Pva-102280	Pteropus vampyrus	84.55	0.00e+00	2182.00
IUUC-Sha-106859	Sarcophilus harrisii	88.32	0.00e+00	2241.00
IUUC-Sar-113714	Sorex araneus	81.98	0.00e+00	1890.00
IUUC-Tgu-117116	Taeniopygia guttata	86.06	0.00e+00	2141.00
IUUC-Tru-118088	Takifugu rubripes	76.13	0.00e+00	1922.00
IUUC-Tsy-119616	Tarsius syrichta	87.97	0.00e+00	1960.00
IUUC-Tni-120284	Tetraodon nigroviridis	74.98	0.00e+00	1870.00
IUUC-Tbe-127900	Tupaia belangeri	92.02	0.00e+00	812.00
IUUC-Ttr-128294	Tursiops truncatus	83.42	0.00e+00	2051.00
IUUC-Vpa-130470	Vicugna pacos	84.71	0.00e+00	1992.00
IUUC-Xtr-132396	Xenopus tropicalis	73.77	0.00e+00	1920.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence