iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020393

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03018238

Gene Name

MDM4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000009669.3	ENSCAFT00000015363.3	ENSCAFP00000014217.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	93.50	0.00e+00	827.00	IUUC-Hsa-046950

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Canis familiaris

Protein Sequence
(Fasta)

MTSFATSAQC STSDSACRIS PEQTNQVRPK LPLLKILQAA GAQGEMFTVK EVMHYLGQYI 60
MVKQLYDQQE QHMVYCGGDL LGELLGRQSF SVKDPSPLYD MLRRNLVTLA TATTDAAQTL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTTATCAAC AGACTGCGAT TTCTTCACTG CCAAAATGAC ATCATTTGCC ACCTCTGCCC 60
AGTGTTCAAC TTCTGACAGT GCTTGCAGGA TCTCCCCAGA ACAAACCAAT CAGGTAAATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome

Interpro

IPR015458--MDM4
IPR016495--p53_neg-reg_MDM_2/4
IPR003121--SWIB_MDM2_domain
IPR001876--Znf_RanBP2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS50089--ZF_RING_2

Pfam

PF02201--SWIB
PF00641--zf-RanBP

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0008283--P:cell proliferation
GO:0071456--P:cellular response to hypoxia
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0045023--P:G0 to G1 transition
GO:0043066--P:negative regulation of apoptotic process
GO:0071157--P:negative regulation of cell cycle arrest
GO:0042177--P:negative regulation of protein catabolic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0006461--P:protein complex assembly
GO:0050821--P:protein stabilization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001467	Ailuropoda melanoleuca	96.75	0.00e+00	853.00
IUUC-Apl-003800	Anas platyrhynchos	60.20	2.00e-154	538.00
IUUC-Aca-004608	Anolis carolinensis	56.10	7.00e-139	487.00
IUUC-Ame-010869	Astyanax mexicanus	47.18	1.00e-106	380.00
IUUC-Bta-013287	Bos taurus	91.26	0.00e+00	875.00
IUUC-Cja-019305	Callithrix jacchus	91.26	0.00e+00	815.00
IUUC-Cpo-022166	Cavia porcellus	89.72	0.00e+00	760.00
IUUC-Csa-023654	Chlorocebus sabaeus	93.50	0.00e+00	811.00
IUUC-Cho-024403	Choloepus hoffmanni	89.18	7.00e-127	446.00
IUUC-Cin-025448	Ciona intestinalis	28.11	1.00e-20	93.20
IUUC-Dre-027754	Danio rerio	48.72	8.00e-117	414.00
IUUC-Dno-029630	Dasypus novemcinctus	88.64	0.00e+00	818.00
IUUC-Dor-031064	Dipodomys ordii	68.90	0.00e+00	644.00
IUUC-Ete-032901	Echinops telfairi	79.51	0.00e+00	764.00
IUUC-Eca-034234	Equus caballus	95.93	0.00e+00	927.00
IUUC-Eeu-035015	Erinaceus europaeus	66.33	2.00e-163	568.00
IUUC-Fca-036587	Felis catus	97.56	0.00e+00	883.00
IUUC-Fal-036906	Ficedula albicollis	54.07	1.00e-137	483.00
IUUC-Gmo-038646	Gadus morhua	43.64	5.00e-94	338.00
IUUC-Gga-040124	Gallus gallus	58.48	4.00e-114	404.00
IUUC-Gac-042397	Gasterosteus aculeatus	46.14	6.00e-105	374.00
IUUC-Ggo-045505	Gorilla gorilla	93.50	0.00e+00	831.00
IUUC-Hsa-046950	Homo sapiens	93.50	0.00e+00	832.00
IUUC-Itr-048886	Ictidomys tridecemlineatus	90.65	0.00e+00	835.00
IUUC-Lch-050141	Latimeria chalumnae	54.96	3.00e-122	431.00
IUUC-Loc-051921	Lepisosteus oculatus	49.70	1.00e-112	400.00
IUUC-Laf-054281	Loxodonta africana	86.99	0.00e+00	785.00
IUUC-Mcc-055462	Macaca mulatta	89.66	0.00e+00	758.00
IUUC-Meu-056294	Macropus eugenii	71.20	3.00e-144	504.00
IUUC-Mga-059924	Meleagris gallopavo	60.32	2.00e-165	575.00
IUUC-Mmr-061428	Microcebus murinus	91.67	0.00e+00	868.00
IUUC-Mdo-062643	Monodelphis domestica	76.31	0.00e+00	724.00
IUUC-Mmu-063229	Mus musculus	82.52	0.00e+00	761.00
IUUC-Mpu-065782	Mustela putorius furo	94.93	0.00e+00	865.00
IUUC-Mlu-068105	Myotis lucifugus	82.56	0.00e+00	783.00
IUUC-Nle-069549	Nomascus leucogenys	93.90	0.00e+00	835.00
IUUC-Opr-070568	Ochotona princeps	89.91	0.00e+00	778.00
IUUC-Ont-072276	Oreochromis niloticus	45.54	3.00e-114	405.00
IUUC-Oan-072787	Ornithorhynchus anatinus	73.62	0.00e+00	656.00
IUUC-Ocu-074912	Oryctolagus cuniculus	90.45	0.00e+00	826.00
IUUC-Ola-087037	Oryzias latipes	43.82	1.00e-94	340.00
IUUC-Oga-088953	Otolemur garnettii	87.70	0.00e+00	805.00
IUUC-Oar-089202	Ovis aries	91.46	0.00e+00	879.00
IUUC-Ptr-090964	Pan troglodytes	93.90	0.00e+00	835.00
IUUC-Pan-091975	Papio anubis	93.29	0.00e+00	825.00
IUUC-Psi-093558	Pelodiscus sinensis	61.79	1.00e-158	552.00
IUUC-Pma-094500	Petromyzon marinus	42.03	3.00e-14	71.60
IUUC-Pfo-096454	Poecilia formosa	46.76	4.00e-109	388.00
IUUC-Pab-098123	Pongo abelii	93.90	0.00e+00	837.00
IUUC-Pca-101112	Procavia capensis	78.30	0.00e+00	725.00
IUUC-Pva-103098	Pteropus vampyrus	83.13	0.00e+00	778.00
IUUC-Rno-105930	Rattus norvegicus	83.16	0.00e+00	739.00
IUUC-Sha-107512	Sarcophilus harrisii	73.83	0.00e+00	645.00
IUUC-Sar-113584	Sorex araneus	84.15	0.00e+00	734.00
IUUC-Tgu-116766	Taeniopygia guttata	55.90	1.00e-100	358.00
IUUC-Tru-117829	Takifugu rubripes	47.43	2.00e-112	399.00
IUUC-Tsy-119268	Tarsius syrichta	78.25	0.00e+00	684.00
IUUC-Tni-120204	Tetraodon nigroviridis	45.81	6.00e-107	380.00
IUUC-Tbe-127840	Tupaia belangeri	84.52	5.00e-125	441.00
IUUC-Ttr-128863	Tursiops truncatus	91.67	0.00e+00	849.00
IUUC-Vpa-130718	Vicugna pacos	93.99	0.00e+00	825.00
IUUC-Xtr-132320	Xenopus tropicalis	46.71	2.00e-89	322.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence