iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000011236.3	ENSMMUT00000056381.1	ENSMMUP00000060422.1
ENSMMUG00000011236.3	ENSMMUT00000045116.2	ENSMMUP00000038135.2
ENSMMUG00000011236.3	ENSMMUT00000015723.3	ENSMMUP00000014729.3
ENSMMUG00000011236.3	ENSMMUT00000045117.2	ENSMMUP00000038136.2
ENSMMUG00000011236.3	ENSMMUT00000045118.2	ENSMMUP00000038137.2
ENSMMUG00000011236.3	ENSMMUT00000045119.2	ENSMMUP00000038138.1
ENSMMUG00000011236.3	ENSMMUT00000063371.1	ENSMMUP00000053282.1
ENSMMUG00000011236.3	ENSMMUT00000045115.2	ENSMMUP00000038134.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	94.50	0.00e+00	803.00	IUUC-Hsa-046950

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MTSFSTSAQC STSDSACRIS PGQINQIPLW RKWVHVTGWP GEGTQVLMVM HYLGQYIMVK 60
QLYDQQEQHM VYCGGDLLGE LLGRQSFSVK DPSPLYDMLR KNLVTLATAT TDAAQTLALA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGATAGCTCA GTCGGTAGAG CATCAGACTT TTAATCTGAG GGTCCAGGGT TCAAGTCCCT 60
GTTCGGGCGT TTGTAGTTTT CGTTACTTTG TATCATCTCA CCAAGTCCGA AATGCGGACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome

Interpro

IPR015458--MDM4
IPR016495--p53_neg-reg_MDM_2/4
IPR003121--SWIB_MDM2_domain
IPR001876--Znf_RanBP2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS50089--ZF_RING_2

Pfam

PF02201--SWIB
PF00641--zf-RanBP

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0008283--P:cell proliferation
GO:0071456--P:cellular response to hypoxia
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0045023--P:G0 to G1 transition
GO:0043066--P:negative regulation of apoptotic process
GO:0071157--P:negative regulation of cell cycle arrest
GO:0042177--P:negative regulation of protein catabolic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0006461--P:protein complex assembly
GO:0050821--P:protein stabilization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001467	Ailuropoda melanoleuca	89.05	0.00e+00	754.00
IUUC-Apl-003800	Anas platyrhynchos	57.17	2.00e-140	492.00
IUUC-Aca-004608	Anolis carolinensis	53.05	2.00e-122	432.00
IUUC-Ame-010869	Astyanax mexicanus	43.52	2.00e-93	336.00
IUUC-Bta-013287	Bos taurus	85.98	0.00e+00	803.00
IUUC-Cja-019305	Callithrix jacchus	91.24	0.00e+00	800.00
IUUC-Cfa-020393	Canis familiaris	89.66	0.00e+00	775.00
IUUC-Cpo-022166	Cavia porcellus	86.18	0.00e+00	706.00
IUUC-Csa-023654	Chlorocebus sabaeus	95.72	0.00e+00	815.00
IUUC-Cho-024403	Choloepus hoffmanni	89.89	6.00e-128	450.00
IUUC-Dre-027754	Danio rerio	46.17	9.00e-104	370.00
IUUC-Dno-029630	Dasypus novemcinctus	85.80	0.00e+00	770.00
IUUC-Dor-031064	Dipodomys ordii	65.58	4.00e-172	597.00
IUUC-Ete-032901	Echinops telfairi	75.66	0.00e+00	706.00
IUUC-Eca-034234	Equus caballus	90.45	0.00e+00	848.00
IUUC-Eeu-035015	Erinaceus europaeus	61.87	3.00e-144	504.00
IUUC-Fca-036587	Felis catus	89.84	0.00e+00	791.00
IUUC-Fal-036906	Ficedula albicollis	51.22	4.00e-125	441.00
IUUC-Gmo-038646	Gadus morhua	41.19	3.00e-83	302.00
IUUC-Gga-040124	Gallus gallus	59.41	1.00e-113	402.00
IUUC-Gac-042397	Gasterosteus aculeatus	43.90	2.00e-93	336.00
IUUC-Ggo-045505	Gorilla gorilla	94.50	0.00e+00	829.00
IUUC-Hsa-046950	Homo sapiens	94.50	0.00e+00	830.00
IUUC-Itr-048886	Ictidomys tridecemlineatus	87.60	0.00e+00	779.00
IUUC-Lch-050141	Latimeria chalumnae	52.19	2.00e-109	389.00
IUUC-Loc-051921	Lepisosteus oculatus	48.12	6.00e-104	371.00
IUUC-Laf-054281	Loxodonta africana	83.13	0.00e+00	727.00
IUUC-Meu-056294	Macropus eugenii	66.13	9.00e-129	453.00
IUUC-Mga-059924	Meleagris gallopavo	57.69	1.00e-151	529.00
IUUC-Mmr-061428	Microcebus murinus	89.02	0.00e+00	819.00
IUUC-Mdo-062643	Monodelphis domestica	72.69	0.00e+00	670.00
IUUC-Mmu-063229	Mus musculus	80.04	0.00e+00	720.00
IUUC-Mpu-065782	Mustela putorius furo	87.45	0.00e+00	763.00
IUUC-Mlu-068105	Myotis lucifugus	77.44	0.00e+00	718.00
IUUC-Nle-069549	Nomascus leucogenys	94.91	0.00e+00	834.00
IUUC-Opr-070568	Ochotona princeps	87.26	0.00e+00	729.00
IUUC-Ont-072276	Oreochromis niloticus	43.91	2.00e-103	369.00
IUUC-Oan-072787	Ornithorhynchus anatinus	69.53	3.00e-173	601.00
IUUC-Ocu-074912	Oryctolagus cuniculus	86.18	0.00e+00	764.00
IUUC-Ola-087037	Oryzias latipes	42.42	2.00e-85	309.00
IUUC-Oga-088953	Otolemur garnettii	85.48	0.00e+00	760.00
IUUC-Oar-089202	Ovis aries	86.38	0.00e+00	810.00
IUUC-Ptr-090964	Pan troglodytes	94.50	0.00e+00	830.00
IUUC-Pan-091975	Papio anubis	95.93	0.00e+00	833.00
IUUC-Psi-093558	Pelodiscus sinensis	57.32	7.00e-143	500.00
IUUC-Pfo-096454	Poecilia formosa	43.47	2.00e-96	345.00
IUUC-Pab-098123	Pongo abelii	94.70	0.00e+00	834.00
IUUC-Pca-101112	Procavia capensis	74.85	0.00e+00	669.00
IUUC-Pva-103098	Pteropus vampyrus	78.86	0.00e+00	716.00
IUUC-Rno-105930	Rattus norvegicus	80.28	0.00e+00	695.00
IUUC-Sha-107512	Sarcophilus harrisii	70.79	4.00e-171	594.00
IUUC-Sar-113584	Sorex araneus	78.05	0.00e+00	660.00
IUUC-Tgu-116766	Taeniopygia guttata	57.01	1.00e-100	359.00
IUUC-Tru-117829	Takifugu rubripes	45.12	2.00e-100	359.00
IUUC-Tsy-119268	Tarsius syrichta	78.62	0.00e+00	672.00
IUUC-Tni-120204	Tetraodon nigroviridis	43.32	9.00e-96	343.00
IUUC-Tbe-127840	Tupaia belangeri	85.06	4.00e-125	441.00
IUUC-Ttr-128863	Tursiops truncatus	86.38	0.00e+00	778.00
IUUC-Vpa-130718	Vicugna pacos	89.42	0.00e+00	759.00
IUUC-Xtr-132320	Xenopus tropicalis	47.05	4.00e-89	321.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence