iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-059533

Ensembl Protein ID

ENSMGAP00000000037.2

UniProt Accession

G1MPS8; G1MPS8_MELGA

Protein Name

Uncharacterized protein

Gene Name

OTUD7B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000000663.2	ENSMGAT00000000666.2	ENSMGAP00000000037.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	1.30e-37	129.0	174	355

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqsllgvfddds.lsdalveaLreltseylqkesdffsefieek...........edekefcqklvepe.... 74
           l+l+t+gDGnCLl+A+s +++g++d+d+ l++ l++ + + +++++ k+++++++++++k           ++e++++ kl+++e    
   Q: 174  LPLATTGDGNCLLHAASLGMWGFHDRDLvLRKSLYTLMDKGVEREALKRRWRWQQTQQNKesglvyteeewQKEWNELIKLASSEprvh 262
           6899*********************************************************************************8877 PP
   S: 75   ..akg.................eeihifaLaqiLsrpiivvdvdsles.........kvggillpllfpeek.lkkpivLlYrsgHYda 134
             + g                 ee+h+f+La++L+rpi+vv++++l++         ++ggi+lpl++p++k +++p+vL+Y+++H++a
   Q: 263  ygTNGggcggvesseepvyeslEEFHVFVLAHVLKRPIVVVADTMLRDsggeafapiPFGGIYLPLEVPANKcHRSPLVLAYDQAHFSA 351
           7522367788******************************************************************************* PP
   S: 135  Lval 138
           Lv++
   Q: 352  LVSM 355
           *986 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

TTLDMDIVLS DFVRSTGAEP GLARDLLEGK NWDLSAALSD FEQLRQVHAG NLPHSFNEGR 60
SYKPPEKEAA RPGRPPLQRQ DDIVQEKRLS RGISHASSTI VSLARSHVSS NGSSEHLLEM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACAACCTTGG ATATGGACAT CGTCCTGTCG GATTTTGTTC GCTCGACAGG GGCAGAGCCA 60
GGACTGGCCA GAGACCTGCT CGAAGGTACG TACGGCTGGG GATGGGACCT GGGAGGAGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom
IPR002653--Znf_A20

PROSITE

PS50802--OTU
PS51036--ZF_A20

Pfam

PF02338--OTU
PF01754--zf-A20

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:1990380--F:Lys48-specific deubiquitinase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0002385--P:mucosal immune response
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032717--P:negative regulation of interleukin-8 production
GO:1900181--P:negative regulation of protein localization to nucleus
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0035871--P:protein K11-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002119	Ailuropoda melanoleuca	68.95	0.00e+00	1007.00
IUUC-Apl-003567	Anas platyrhynchos	83.76	0.00e+00	1203.00
IUUC-Bta-013398	Bos taurus	69.52	0.00e+00	981.00
IUUC-Cel-018468	Caenorhabditis elegans	49.16	4.00e-84	305.00
IUUC-Cja-019965	Callithrix jacchus	67.33	0.00e+00	1002.00
IUUC-Cfa-020191	Canis familiaris	69.06	0.00e+00	1002.00
IUUC-Cpo-022232	Cavia porcellus	67.64	0.00e+00	954.00
IUUC-Csa-023593	Chlorocebus sabaeus	68.91	0.00e+00	1053.00
IUUC-Csv-026177	Ciona savignyi	32.20	8.00e-03	33.50
IUUC-Dno-029900	Dasypus novemcinctus	68.48	0.00e+00	968.00
IUUC-Dor-031121	Dipodomys ordii	75.58	8.00e-175	605.00
IUUC-Ete-032473	Echinops telfairi	72.60	0.00e+00	826.00
IUUC-Eca-033946	Equus caballus	77.55	0.00e+00	850.00
IUUC-Eeu-034670	Erinaceus europaeus	68.37	0.00e+00	961.00
IUUC-Fca-035871	Felis catus	68.38	0.00e+00	960.00
IUUC-Gmo-039373	Gadus morhua	82.38	0.00e+00	716.00
IUUC-Gga-041105	Gallus gallus	93.71	0.00e+00	1446.00
IUUC-Gac-041806	Gasterosteus aculeatus	61.56	0.00e+00	892.00
IUUC-Ggo-045472	Gorilla gorilla	68.79	0.00e+00	1014.00
IUUC-Hsa-046473	Homo sapiens	68.79	0.00e+00	1021.00
IUUC-Itr-048841	Ictidomys tridecemlineatus	69.41	0.00e+00	1005.00
IUUC-Lch-050432	Latimeria chalumnae	70.62	0.00e+00	1065.00
IUUC-Mcc-055261	Macaca mulatta	68.79	0.00e+00	1053.00
IUUC-Meu-056477	Macropus eugenii	65.67	0.00e+00	776.00
IUUC-Mdo-062847	Monodelphis domestica	67.40	0.00e+00	957.00
IUUC-Mmu-064260	Mus musculus	67.71	0.00e+00	936.00
IUUC-Mpu-066876	Mustela putorius furo	66.16	0.00e+00	933.00
IUUC-Mlu-068039	Myotis lucifugus	68.29	0.00e+00	1009.00
IUUC-Nle-069260	Nomascus leucogenys	69.08	0.00e+00	1021.00
IUUC-Opr-070564	Ochotona princeps	80.91	0.00e+00	675.00
IUUC-Ocu-073824	Oryctolagus cuniculus	82.33	0.00e+00	823.00
IUUC-Ola-086490	Oryzias latipes	57.13	0.00e+00	838.00
IUUC-Oga-088124	Otolemur garnettii	68.66	0.00e+00	985.00
IUUC-Oar-090086	Ovis aries	69.52	0.00e+00	978.00
IUUC-Ptr-091622	Pan troglodytes	77.73	0.00e+00	896.00
IUUC-Pan-092724	Papio anubis	68.68	0.00e+00	1045.00
IUUC-Psi-093333	Pelodiscus sinensis	78.75	0.00e+00	1194.00
IUUC-Pab-098667	Pongo abelii	69.11	0.00e+00	1012.00
IUUC-Pva-102136	Pteropus vampyrus	67.84	0.00e+00	973.00
IUUC-Rno-105546	Rattus norvegicus	68.52	0.00e+00	955.00
IUUC-Sha-106732	Sarcophilus harrisii	65.88	0.00e+00	867.00
IUUC-Sar-113562	Sorex araneus	61.59	0.00e+00	790.00
IUUC-Ssc-116191	Sus scrofa	69.64	0.00e+00	992.00
IUUC-Tgu-116942	Taeniopygia guttata	88.24	0.00e+00	918.00
IUUC-Tsy-119343	Tarsius syrichta	71.12	0.00e+00	886.00
IUUC-Tur-126860	Triticum urartu	21.95	4.60e-01	28.90
IUUC-Tbe-127283	Tupaia belangeri	80.82	0.00e+00	666.00
IUUC-Ttr-128692	Tursiops truncatus	65.59	0.00e+00	898.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence