iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Cancer Mutation
TCGA	COSMIC	CGAP	IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	TCGA	ICGC	COSMIC
HPM
DNA & RNA Element
miRTarBase	microRNA	TRANSFAC	miRWalk
RepTar	SomamiR	miRcode	RAID2
Protein-protein Interaction
IID	PINA	HINT	Mentha
Post-translational Modifications (PTMs)
CPLM	dbPAF	PhosphositePlus	dbPTM
HPRD	BioGRID	mUbiSiDa
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	5.80e-39	134.7	7	140

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilG.pedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeek 91
           R+ ke+++l ++p++gi+a+p+++ +   ++v+i G  +d+p+egg+Fk e+ + e+YP+ +Pkv+f+tki+hPnv++  ++  +ilk  +k
   Q: 7    RIIKETQRLLAEPVPGIKAEPDES-NARYFHVVIAGeSKDSPFEGGTFKRELLLAEEYPMAAPKVRFMTKIYHPNVDKLERISXDILK--DK 95
           899*********************.9**********6689***********************************************9..** PP
   S: 92   Wspalsvesvllsiqsllaepnpesplneeaaellkknreeykkk 136
           Wspal++++vllsiq+ll+ pnp++pl ++++e++k+n+++  ++
   Q: 96   WSPALQIRTVLLSIQALLNAPNPDDPLANDVVEQWKTNEAQAIET 140
           **************************************9976655 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MAELPHRIIK ETQRLLAEPV PGIKAEPDES NARYFHVVIA GESKDSPFEG GTFKRELLLA 60
EEYPMAAPKV RFMTKIYHPN VDKLERISXD ILKDKWSPAL QIRTVLLSIQ ALLNAPNPDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATGAGACCA GAGGCCGAAC TCAGGTTCTG ATGGCCGAGC TGCCCCACAG GATCATCAAG 60
GAAACCCAGC GTTTGCTGGC AGAGCCAGTT CCTGGCATCA AAGCAGAACC AGATGAAAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0006301--P:postreplication repair
GO:0070534--P:protein K63-linked ubiquitination

KEGG

hsa:389898

Orthology

iUUCD ID

Species

Identity

E-value

Score

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence