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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046433
Ensembl Protein ID ENSP00000334996.2
UniProt Accession Q13939; Q9BXG7; CALI_HUMAN
Genbank Protein ID AAK20829.1; CAA87088.1
Protein Name Calicin
Genbank Nucleotide ID AF333334; Z46967
Gene Name CCIN
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000185972.5 ENST00000335119.3 ENSP00000334996.2
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICHPM
DNA & RNA Element
UTRdbAREsitemiRTarBasemicroRNA
TRANSFACTargetScanRepTarmiRNAMap
miRcodeRAID2
Protein-protein Interaction
IIDiRefIndexPINAMentha
Disease-associated Variation
OMIM
Post-translational Modifications (PTMs)
dbPAFPhosphositePlus
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB 4.10e-09 38.3 29 97
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/BCR/BTB_Other: BTB
   S: 2    DvilvvggeeffahkivLaasSsvFyalf.lmeleesksklmveik.d.vqpevfrallkFlYtgklden 68
           D+ l v++ +ffah+ vLaa S+  ++l+ +++++  + +l ++i+   ++p  + +ll++ Y+gk+ ++
   Q: 29   DMALSVDNHVFFAHRNVLAAVSPLVRSLIsSNDMKTAD-ELFITIDtSyLSPVTVDQLLDYFYSGKVVIS 97
           78999************************888888888.*******637*****************9876 PP
   
Organism Homo sapiens
Functional Description
(View)

Functional Description


     Testis. Not detectable or shows a drastically altered pattern of arrangement in the heads of malformed spermatozoa.
 Testis. Not detectable or shows a drastically altered pattern of arrangement in the heads of malformed spermatozoa.
Protein Sequence
(Fasta)
MKLEFTEKNY NSFVLQNLNR QRKRKEYWDM ALSVDNHVFF AHRNVLAAVS PLVRSLISSN 60
DMKTADELFI TIDTSYLSPV TVDQLLDYFY SGKVVISEQN VEELLRGAQY FNTPRLRVHC 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046433|E3,BTB_Other|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TCTCCCTGGT CAACCGCTCT GCAAACAACC ATCAATCTGA TCCCACAGGC CTGAGAAAGT 60
CTGCTCTCCA GTACCTGCTG CTGATCTGTT TCAGCCGACA AGAGGCACCA TGAAATTGGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046433|E3,BTB_Other|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0217--Developmental protein
KW-0221--Differentiation
KW-0880--Kelch repeat
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0744--Spermatogenesis
Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ
PROSITE

PS50097--BTB
Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1
SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch
Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0033150--C:cytoskeletal calyx
GO:0005634--C:nucleus
GO:0003779--F:actin binding
GO:0030154--P:cell differentiation
GO:0007275--P:multicellular organism development
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0007283--P:spermatogenesis
KEGG hsa:881
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001471 Ailuropoda melanoleuca 93.54 0.00e+00 1167.00
IUUC-Aca-004588 Anolis carolinensis 60.14 0.00e+00 764.00
IUUC-Bta-012811 Bos taurus 91.50 0.00e+00 1117.00
IUUC-Cja-019280 Callithrix jacchus 96.10 0.00e+00 1149.00
IUUC-Cfa-021268 Canis familiaris 93.20 0.00e+00 1166.00
IUUC-Cpo-022358 Cavia porcellus 88.27 0.00e+00 1104.00
IUUC-Csa-023527 Chlorocebus sabaeus 97.45 0.00e+00 1147.00
IUUC-Dno-029107 Dasypus novemcinctus 93.20 0.00e+00 1167.00
IUUC-Dor-030337 Dipodomys ordii 88.44 0.00e+00 1088.00
IUUC-Ete-032606 Echinops telfairi 93.03 0.00e+00 1165.00
IUUC-Eca-034273 Equus caballus 86.10 0.00e+00 1021.00
IUUC-Eeu-035355 Erinaceus europaeus 93.20 0.00e+00 1165.00
IUUC-Fca-036204 Felis catus 93.71 0.00e+00 1163.00
IUUC-Ggo-045558 Gorilla gorilla 98.98 0.00e+00 1217.00
IUUC-Itr-048395 Ictidomys tridecemlineatus 93.88 0.00e+00 1133.00
IUUC-Lch-050104 Latimeria chalumnae 54.95 5.00e-179 620.00
IUUC-Laf-054528 Loxodonta africana 93.88 0.00e+00 1175.00
IUUC-Mcc-055129 Macaca mulatta 97.79 0.00e+00 1170.00
IUUC-Mpo-057374 Magnaporthe poae 34.33 3.00e-05 43.50
IUUC-Mmr-061547 Microcebus murinus 94.05 0.00e+00 1158.00
IUUC-Mdo-061998 Monodelphis domestica 81.80 0.00e+00 1020.00
IUUC-Mmu-064007 Mus musculus 93.03 0.00e+00 1103.00
IUUC-Mpu-066791 Mustela putorius furo 93.88 0.00e+00 1171.00
IUUC-Nle-069625 Nomascus leucogenys 96.60 0.00e+00 1189.00
IUUC-Opr-070410 Ochotona princeps 93.03 0.00e+00 1147.00
IUUC-Oan-073301 Ornithorhynchus anatinus 73.42 0.00e+00 913.00
IUUC-Ocu-074131 Oryctolagus cuniculus 92.86 0.00e+00 1145.00
IUUC-Oga-088044 Otolemur garnettii 94.22 0.00e+00 1159.00
IUUC-Oar-090106 Ovis aries 91.84 0.00e+00 1149.00
IUUC-Ptr-091169 Pan troglodytes 99.66 0.00e+00 1227.00
IUUC-Psi-093438 Pelodiscus sinensis 69.22 0.00e+00 892.00
IUUC-Pab-097818 Pongo abelii 97.79 0.00e+00 1206.00
IUUC-Pva-102448 Pteropus vampyrus 91.39 0.00e+00 701.00
IUUC-Rno-105305 Rattus norvegicus 93.03 0.00e+00 1103.00
IUUC-Sha-106813 Sarcophilus harrisii 82.82 0.00e+00 996.00
IUUC-Ssc-116432 Sus scrofa 92.35 0.00e+00 1140.00
IUUC-Tbe-127443 Tupaia belangeri 93.03 0.00e+00 1161.00
Created Date 25-Jun-2017

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