iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-087943

Ensembl Protein ID

ENSOGAP00000016795.1

UniProt Accession

H0XL05; H0XL05_OTOGA

Genbank Protein ID

ENSOGAP00000016795

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03164239

Gene Name

CISH

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000031755.1	ENSOGAT00000034005.1	ENSOGAP00000016795.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	8.80e-15	54.3	208	255

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 1    lsklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           l++++++rs+ rSLqhLCRl+I+r++ +     +d+LPLP+++ dYL+++++q
   Q: 208  LVQPFVRRSSARSLQHLCRLVINRLVAD-----VDCLPLPRRMADYLRQYPFQ 255
           57999***********************.....8****************986 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MVLCVQGPCP LLAVEQIGQR LLSQSLELPE SIMKPLPAGA FLEEVAEETS AQSESEPKVL 60
DPEEDLLCIA KTFSYLRESG WYWGSITASE ARQHLQKMPE GTFLVRDSTH PSYLFTLSVK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTCCTCT GCGTTCAGGG GTAAGCGCCT CTCACCGTCC CCGCCCAACC TCTGCTCAGG 60
GCTCACAGGA AAGCACCAGC CTCGGGCTAG CTGCGGAGCA TTGGGAGGGC TTCACCTGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028425--CIS
IPR000980--SH2
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

PRINTS

PR00401--SH2DOMAIN

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0005886--C:plasma membrane
GO:0035556--P:intracellular signal transduction
GO:0007205--P:protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001189	Ailuropoda melanoleuca	92.46	2.00e-120	424.00
IUUC-Aca-004372	Anolis carolinensis	64.23	3.00e-89	320.00
IUUC-Ago-007964	Ashbya gossypii	28.00	2.00e+00	26.20
IUUC-Ame-010787	Astyanax mexicanus	45.70	4.00e-51	194.00
IUUC-Bta-012826	Bos taurus	89.11	9.00e-127	445.00
IUUC-Cja-020004	Callithrix jacchus	89.64	7.00e-113	399.00
IUUC-Cfa-020150	Canis familiaris	90.40	6.00e-113	399.00
IUUC-Csa-023173	Chlorocebus sabaeus	89.24	2.00e-112	398.00
IUUC-Dre-028606	Danio rerio	44.13	7.00e-34	136.00
IUUC-Dno-028956	Dasypus novemcinctus	88.67	1.00e-122	432.00
IUUC-Dor-030148	Dipodomys ordii	71.98	4.00e-96	343.00
IUUC-Ete-032313	Echinops telfairi	82.81	8.00e-104	369.00
IUUC-Eca-033422	Equus caballus	92.61	2.00e-131	461.00
IUUC-Eeu-034806	Erinaceus europaeus	91.20	3.00e-110	390.00
IUUC-Fca-036374	Felis catus	92.61	7.00e-124	436.00
IUUC-Fal-036801	Ficedula albicollis	66.28	7.00e-89	320.00
IUUC-Gmo-038483	Gadus morhua	41.87	2.00e-34	139.00
IUUC-Gga-040891	Gallus gallus	67.31	3.00e-83	301.00
IUUC-Gac-042147	Gasterosteus aculeatus	39.38	8.00e-34	136.00
IUUC-Ggo-045511	Gorilla gorilla	89.24	6.00e-111	393.00
IUUC-Hsa-046678	Homo sapiens	89.15	1.00e-114	405.00
IUUC-Itr-048397	Ictidomys tridecemlineatus	93.00	3.00e-130	457.00
IUUC-Lch-050555	Latimeria chalumnae	53.85	7.00e-73	266.00
IUUC-Laf-054141	Loxodonta africana	89.15	5.00e-125	439.00
IUUC-Mcc-055401	Macaca mulatta	88.84	4.00e-111	394.00
IUUC-Meu-056592	Macropus eugenii	68.00	1.00e-90	325.00
IUUC-Mga-059515	Meleagris gallopavo	66.28	8.00e-79	286.00
IUUC-Mmr-060848	Microcebus murinus	93.60	3.00e-119	421.00
IUUC-Mdo-062720	Monodelphis domestica	66.54	2.00e-93	335.00
IUUC-Mmu-063348	Mus musculus	90.66	4.00e-134	469.00
IUUC-Mpu-065834	Mustela putorius furo	91.83	3.00e-122	431.00
IUUC-Mlu-067687	Myotis lucifugus	86.72	7.00e-103	366.00
IUUC-Nle-069277	Nomascus leucogenys	89.15	1.00e-115	408.00
IUUC-Ont-071890	Oreochromis niloticus	46.07	8.00e-37	146.00
IUUC-Oan-073672	Ornithorhynchus anatinus	66.41	2.00e-87	315.00
IUUC-Ocu-073875	Oryctolagus cuniculus	91.60	5.00e-122	430.00
IUUC-Ola-087140	Oryzias latipes	45.03	1.00e-24	105.00
IUUC-Oar-090194	Ovis aries	88.10	4.00e-122	430.00
IUUC-Ptr-090934	Pan troglodytes	88.45	1.00e-108	385.00
IUUC-Pan-092121	Papio anubis	89.15	6.00e-116	409.00
IUUC-Psi-093733	Pelodiscus sinensis	63.10	9.00e-83	299.00
IUUC-Pfo-096313	Poecilia formosa	48.26	2.00e-44	171.00
IUUC-Pab-098439	Pongo abelii	89.15	6.00e-114	403.00
IUUC-Pca-101010	Procavia capensis	87.60	1.00e-121	429.00
IUUC-Pva-103112	Pteropus vampyrus	90.66	1.00e-124	438.00
IUUC-Rno-105917	Rattus norvegicus	89.88	3.00e-118	417.00
IUUC-Sha-106954	Sarcophilus harrisii	66.02	9.00e-96	342.00
IUUC-Smo-109292	Selaginella moellendorffii	31.15	1.30e-01	31.20
IUUC-Sar-113001	Sorex araneus	91.20	8.00e-117	412.00
IUUC-Ssc-115922	Sus scrofa	90.78	1.00e-64	238.00
IUUC-Tgu-117338	Taeniopygia guttata	66.53	8.00e-85	306.00
IUUC-Tru-118511	Takifugu rubripes	45.51	3.00e-33	134.00
IUUC-Tsy-119434	Tarsius syrichta	90.40	3.00e-115	407.00
IUUC-Tni-119837	Tetraodon nigroviridis	40.93	8.00e-30	123.00
IUUC-Ttr-128340	Tursiops truncatus	74.71	1.00e-85	308.00
IUUC-Vpa-130443	Vicugna pacos	92.22	6.00e-135	473.00
IUUC-Xtr-131784	Xenopus tropicalis	50.55	9.00e-68	249.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence