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Basic Information Integrated Annotations

Tag Content
UUCD2 ID IUUC-Mmu-063314
UUCD1 version UUC-MuM-00712
Ensembl Protein ID ENSMUSP00000106149.2
UniProt Accession Q8C7M3; Q6ZQE5; Q80WT6; Q8C7Z4; Q8CC32; Q8CEG2; Q99PQ3; TRIM9_MOUSE
Genbank Protein ID BAC33982.1; BAC28552.1; BAC25854.1; BAC33479.1; BAC97919.1; AAH52034.1; AAG53493.1
Protein Name E3 ubiquitin-protein ligase TRIM9; RING-type E3 ubiquitin transferase TRIM9; Tripartite motif-containing protein 9
Genbank Nucleotide ID AK049907; AK034029; AK028280; AK048875; AK129109; BC052034; AF220039
Gene Name Trim9; Kiaa0282
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000021071.15 ENSMUST00000110522.8 ENSMUSP00000106151.2
ENSMUSG00000021071.15 ENSMUST00000110520.8 ENSMUSP00000106149.2
ENSMUSG00000021071.15 ENSMUST00000167755.1 ENSMUSP00000127081.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarRAID2
Protein-protein Interaction
IIDMentha
Post-translational Modifications (PTMs)
dbPAFPhosphositePlusdbPTMUniProt
PHOSIDA
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 92.35 0.00e+00 1338.00 IUUC-Hsa-046503
E3 activity/RING/RING 94.40 0.00e+00 1361.00 IUUC-Rno-105306
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Mus musculus
Functional Description
(View)

Functional Description



     E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation. May play a role in regulation of neuronal functions. May act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation.
E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation. May play a role in regulation of neuronal functions. May act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation.
Protein Sequence
(Fasta)
MEEMEEELKC PVCGSFYREP IILPCSHNLC QACARNILVQ TPESESPQSR RASGSGVSDY 60
DYLDLDKMSL YSEADSGYGS YGGFASAPTT PCQKSPNGVR VFPPAMPPPP THLSPALAPV 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Mmu-063314|E3,RING|Mus musculus
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Nucleotide Sequence
(Fasta)
GGGGGTAGGA AAGGATGAAT CATCCCGCCC CACTTCTTCT CGGCTTGCGC CAGCCCCCTC 60
CTAAAATCCC GCAGCAGCCA GCAGGCGATG CCGGGGCTCC AGCTCCGACT CATAGAGCCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Mmu-063314|E3,RING|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0965--Cell junction
KW-0966--Cell projection
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0206--Cytoskeleton
KW-0479--Metal-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0770--Synapse
KW-0808--Transferase
KW-0832--Ubl conjugation
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003649--Bbox_C
IPR013320--ConA-like_dom
IPR017903--COS_domain
IPR003961--FN3_dom
IPR013783--Ig-like_fold
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS51262--COS
PS50853--FN3
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00041--fn3
PF00622--SPRY
PF00643--zf-B_box

SMART

SM00502--BBC
SM00336--BBOX
SM00060--FN3
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0030054--C:cell junction
GO:0005737--C:cytoplasm
GO:0005856--C:cytoskeleton
GO:0005829--C:cytosol
GO:0030425--C:dendrite
GO:0008021--C:synaptic vesicle
GO:0042803--F:protein homodimerization activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0016079--P:synaptic vesicle exocytosis

KEGG mmu:94090
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002033 Ailuropoda melanoleuca 87.36 0.00e+00 823.00
IUUC-Apl-004004 Anas platyrhynchos 85.38 0.00e+00 1079.00
IUUC-Ame-011775 Astyanax mexicanus 65.92 0.00e+00 994.00
IUUC-Bta-013184 Bos taurus 92.08 0.00e+00 1355.00
IUUC-Cfa-020744 Canis familiaris 82.89 0.00e+00 1291.00
IUUC-Cpo-021775 Cavia porcellus 88.82 0.00e+00 1369.00
IUUC-Csa-024085 Chlorocebus sabaeus 97.61 0.00e+00 1070.00
IUUC-Cho-024738 Choloepus hoffmanni 72.50 0.00e+00 701.00
IUUC-Csv-025851 Ciona savignyi 41.82 8.00e-169 587.00
IUUC-Dre-027691 Danio rerio 78.05 0.00e+00 1209.00
IUUC-Dno-029047 Dasypus novemcinctus 92.62 0.00e+00 1363.00
IUUC-Dor-030823 Dipodomys ordii 75.70 0.00e+00 1096.00
IUUC-Dme-031822 Drosophila melanogaster 43.18 2.00e-151 529.00
IUUC-Eeu-034494 Erinaceus europaeus 97.92 0.00e+00 767.00
IUUC-Fca-036046 Felis catus 84.85 0.00e+00 1307.00
IUUC-Gmo-039639 Gadus morhua 79.33 0.00e+00 1174.00
IUUC-Gga-040951 Gallus gallus 86.05 0.00e+00 1266.00
IUUC-Gac-041390 Gasterosteus aculeatus 80.97 0.00e+00 1231.00
IUUC-Ggo-045059 Gorilla gorilla 85.32 0.00e+00 1329.00
IUUC-Hsa-046503 Homo sapiens 92.35 0.00e+00 1360.00
IUUC-Itr-049084 Ictidomys tridecemlineatus 86.06 0.00e+00 1315.00
IUUC-Lch-049521 Latimeria chalumnae 76.94 0.00e+00 1156.00
IUUC-Loc-052213 Lepisosteus oculatus 80.44 0.00e+00 1185.00
IUUC-Laf-054442 Loxodonta africana 92.76 0.00e+00 1364.00
IUUC-Mcc-054887 Macaca mulatta 92.62 0.00e+00 1362.00
IUUC-Meu-056251 Macropus eugenii 77.89 0.00e+00 1182.00
IUUC-Mmr-061677 Microcebus murinus 93.17 0.00e+00 1370.00
IUUC-Mdo-062987 Monodelphis domestica 84.91 0.00e+00 1349.00
IUUC-Mpu-066785 Mustela putorius furo 83.02 0.00e+00 1291.00
IUUC-Mlu-067137 Myotis lucifugus 92.62 0.00e+00 1361.00
IUUC-Nle-070127 Nomascus leucogenys 92.76 0.00e+00 1364.00
IUUC-Opr-070763 Ochotona princeps 84.09 0.00e+00 1266.00
IUUC-Ont-071416 Oreochromis niloticus 81.10 0.00e+00 1235.00
IUUC-Oan-072901 Ornithorhynchus anatinus 75.79 0.00e+00 750.00
IUUC-Ocu-074241 Oryctolagus cuniculus 88.31 0.00e+00 1381.00
IUUC-Ola-086349 Oryzias latipes 72.22 5.00e-100 356.00
IUUC-Oga-088969 Otolemur garnettii 84.72 0.00e+00 1317.00
IUUC-Oar-089807 Ovis aries 91.26 0.00e+00 1337.00
IUUC-Ptr-090952 Pan troglodytes 86.23 0.00e+00 1319.00
IUUC-Pan-092565 Papio anubis 88.10 0.00e+00 1358.00
IUUC-Psi-093885 Pelodiscus sinensis 84.58 0.00e+00 869.00
IUUC-Pfo-096684 Poecilia formosa 79.75 0.00e+00 1228.00
IUUC-Pab-097638 Pongo abelii 92.76 0.00e+00 1358.00
IUUC-Pca-101102 Procavia capensis 96.15 0.00e+00 1052.00
IUUC-Pva-103204 Pteropus vampyrus 79.68 0.00e+00 783.00
IUUC-Rno-105306 Rattus norvegicus 94.40 0.00e+00 1361.00
IUUC-Sar-113631 Sorex araneus 86.01 0.00e+00 1317.00
IUUC-Sbi-114403 Sorghum bicolor 26.89 5.00e-05 42.00
IUUC-Ssc-115634 Sus scrofa 92.35 0.00e+00 1362.00
IUUC-Tru-117583 Takifugu rubripes 78.96 0.00e+00 1207.00
IUUC-Tsy-119427 Tarsius syrichta 79.32 0.00e+00 785.00
IUUC-Tni-120847 Tetraodon nigroviridis 78.66 0.00e+00 1207.00
IUUC-Tbe-127239 Tupaia belangeri 81.57 0.00e+00 941.00
IUUC-Ttr-129238 Tursiops truncatus 77.50 0.00e+00 762.00
IUUC-Vpa-130241 Vicugna pacos 83.31 0.00e+00 1236.00
IUUC-Xtr-131998 Xenopus tropicalis 84.65 0.00e+00 1253.00
Created Date 25-Jun-2017

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