iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
miRTarBase	microRNA	TRANSFAC	RepTar
RAID2
Protein-protein Interaction
IID	HINT
Post-translational Modifications (PTMs)
CPLM	dbPAF	PhosphositePlus	dbPTM
UniProt	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UIM	2.40e-07	31.1	229	247
UBD/Alpha-Helix/UIM	1.7e-05	16.4	202	220

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UIM

   S: 1    dEdeeLqlAlalSlqEeee 19
           dEd++LqlAl lS+qE+e+
   Q: 229  DEDLQLQLALSLSRQEHEK 247
           7***************995 PP

UBD/Alpha-Helix/UIM

   S: 1    dEdeeLqlAlalSlqEeee 19
           +E+++LqlAla+S++E+e+
   Q: 202  EEELQLQLALAMSREEAER 220
           79***************95 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MTTSALRRQV KNIVHNYSEA EIKVREATSN DPWGPPSSLM SEIADLTFNT VAFAEVMGMV 60
WRRLNDSGKN WRHVYKALTL LDYLLKTGSE RVAHQCRENL YTIQTLKDFQ YIDRDGKDQG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGAGGCAGAC CTGCCTGGCC AGCTGAACAA CTTTCCTCCC GAGAGTGCTG GCCGGCAGGA 60
GTCGAGGAGG CAGCCGCGAG AGTCTGAGCG GCCACCCGCT GGGGGGACCC TGCGGTCCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0446--Lipid-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR013809--ENTH
IPR008942--ENTH_VHS
IPR027318--Epsin-3_metazoa
IPR003903--UIM_dom

PROSITE

PS50942--ENTH
PS50330--UIM

Pfam

PF01417--ENTH
PF02809--UIM

SMART

SM00273--ENTH
SM00726--UIM

Gene Ontology

GO:0005938--C:cell cortex
GO:0005905--C:clathrin-coated pit
GO:0030136--C:clathrin-coated vesicle
GO:0070062--C:extracellular exosome
GO:0019897--C:extrinsic component of plasma membrane
GO:0043231--C:intracellular membrane-bounded organelle
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:1990175--F:EH domain binding
GO:0008289--F:lipid binding

KEGG

mmu:71889

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002202	Ailuropoda melanoleuca	79.03	1.00e-138	485.00
IUUC-Aca-005019	Anolis carolinensis	63.90	4.00e-176	611.00
IUUC-Acl-008167	Aspergillus clavatus	52.27	4.00e-38	152.00
IUUC-Afl-008626	Aspergillus flavus	54.10	6.00e-36	145.00
IUUC-Afu-009110	Aspergillus fumigatus	52.27	3.00e-38	153.00
IUUC-Ani-009183	Aspergillus nidulans	52.27	5.00e-37	149.00
IUUC-Ang-009835	Aspergillus niger	53.79	8.00e-39	155.00
IUUC-Aor-009899	Aspergillus oryzae	53.03	3.00e-38	153.00
IUUC-Ate-010292	Aspergillus terreus	54.55	4.00e-39	156.00
IUUC-Bgr-012103	Blumeria graminis	51.57	4.00e-44	172.00
IUUC-Bta-012344	Bos taurus	75.84	0.00e+00	777.00
IUUC-Bci-013887	Botrytis cinerea	56.82	1.00e-40	160.00
IUUC-Cja-018801	Callithrix jacchus	84.79	0.00e+00	818.00
IUUC-Cfa-020215	Canis familiaris	85.62	0.00e+00	860.00
IUUC-Cpo-021844	Cavia porcellus	81.45	0.00e+00	773.00
IUUC-Csa-024257	Chlorocebus sabaeus	83.31	0.00e+00	822.00
IUUC-Cgl-026614	Colletotrichum gloeosporioides	55.92	2.00e-46	180.00
IUUC-Dre-027620	Danio rerio	46.12	4.00e-96	345.00
IUUC-Dno-029944	Dasypus novemcinctus	71.31	0.00e+00	717.00
IUUC-Dor-030270	Dipodomys ordii	80.28	0.00e+00	848.00
IUUC-Dse-031529	Dothistroma septosporum	49.07	8.00e-43	168.00
IUUC-Eca-033368	Equus caballus	83.26	0.00e+00	849.00
IUUC-Fca-035598	Felis catus	83.14	0.00e+00	728.00
IUUC-Fal-036930	Ficedula albicollis	58.70	3.00e-161	561.00
IUUC-Gmo-039660	Gadus morhua	47.83	1.00e-97	350.00
IUUC-Ggr-039910	Gaeumannomyces graminis	55.92	2.00e-46	180.00
IUUC-Gga-040600	Gallus gallus	62.98	6.00e-150	524.00
IUUC-Gac-042303	Gasterosteus aculeatus	51.60	5.00e-97	348.00
IUUC-Ggo-045604	Gorilla gorilla	84.65	0.00e+00	822.00
IUUC-Hsa-046054	Homo sapiens	85.71	0.00e+00	836.00
IUUC-Itr-048835	Ictidomys tridecemlineatus	86.88	0.00e+00	873.00
IUUC-Lch-050652	Latimeria chalumnae	55.99	2.00e-135	476.00
IUUC-Loc-052572	Lepisosteus oculatus	55.18	6.00e-122	431.00
IUUC-Lma-053140	Leptosphaeria maculans	53.73	3.00e-39	157.00
IUUC-Laf-054462	Loxodonta africana	82.79	0.00e+00	846.00
IUUC-Mcc-055207	Macaca mulatta	83.31	0.00e+00	816.00
IUUC-Meu-056064	Macropus eugenii	67.33	0.00e+00	723.00
IUUC-Mor-057254	Magnaporthe oryzae	55.92	2.00e-46	180.00
IUUC-Mpo-057426	Magnaporthe poae	56.58	3.00e-46	179.00
IUUC-Mla-058947	Melampsora laricipopulina	57.05	6.00e-46	178.00
IUUC-Mga-059375	Meleagris gallopavo	63.64	3.00e-153	535.00
IUUC-Mmr-061041	Microcebus murinus	84.60	0.00e+00	818.00
IUUC-Mdo-062185	Monodelphis domestica	76.70	0.00e+00	805.00
IUUC-Mpu-066311	Mustela putorius furo	84.80	0.00e+00	873.00
IUUC-Mlu-067152	Myotis lucifugus	76.28	4.00e-172	598.00
IUUC-Nfi-068548	Neosartorya fischeri	52.27	3.00e-38	152.00
IUUC-Nle-069899	Nomascus leucogenys	82.48	0.00e+00	811.00
IUUC-Opr-070654	Ochotona princeps	80.78	0.00e+00	835.00
IUUC-Oan-072854	Ornithorhynchus anatinus	63.36	3.00e-162	565.00
IUUC-Ocu-074810	Oryctolagus cuniculus	84.74	0.00e+00	785.00
IUUC-Oga-088099	Otolemur garnettii	77.65	0.00e+00	697.00
IUUC-Oar-090276	Ovis aries	80.33	0.00e+00	813.00
IUUC-Pan-092255	Papio anubis	82.79	0.00e+00	826.00
IUUC-Psi-093981	Pelodiscus sinensis	60.61	2.00e-167	582.00
IUUC-Pno-095066	Phaeosphaeria nodorum	55.96	4.00e-32	132.00
IUUC-Pfo-096086	Poecilia formosa	47.08	5.00e-97	348.00
IUUC-Pab-098401	Pongo abelii	84.79	0.00e+00	821.00
IUUC-Pca-100477	Procavia capensis	79.07	0.00e+00	843.00
IUUC-Pva-102611	Pteropus vampyrus	67.33	3.00e-108	385.00
IUUC-Pgr-103451	Puccinia graminis	60.47	3.00e-42	165.00
IUUC-Pte-104048	Pyrenophora teres	53.79	1.00e-38	154.00
IUUC-Pyt-104596	Pyrenophora triticirepentis	53.79	2.00e-38	154.00
IUUC-Rno-105902	Rattus norvegicus	90.41	0.00e+00	924.00
IUUC-Sha-107372	Sarcophilus harrisii	76.27	0.00e+00	798.00
IUUC-Sja-107671	Schizosaccharomyces japonicus	50.67	6.00e-42	165.00
IUUC-Ssl-108625	Sclerotinia sclerotiorum	56.82	2.00e-40	160.00
IUUC-Sar-112960	Sorex araneus	95.24	6.00e-95	341.00
IUUC-Ssc-115921	Sus scrofa	77.29	0.00e+00	766.00
IUUC-Tgu-117395	Taeniopygia guttata	63.28	2.00e-175	608.00
IUUC-Tru-118176	Takifugu rubripes	45.05	4.00e-91	328.00
IUUC-Tre-122134	Trichoderma reesei	52.17	4.00e-44	172.00
IUUC-Tvi-122308	Trichoderma virens	52.17	2.00e-44	173.00
IUUC-Tme-127215	Tuber melanosporum	54.23	2.00e-43	170.00
IUUC-Ttr-128552	Tursiops truncatus	84.35	1.00e-165	576.00
IUUC-Vda-129905	Verticillium dahliae	55.26	9.00e-45	174.00
IUUC-Xma-133053	Xiphophorus maculatus	52.41	6.00e-112	398.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence