iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-013499

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Cell division cycle protein 27 homolog

Genbank Nucleotide ID

BC153259

Gene Name

CDC27

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000002726.4	ENSBTAT00000003533.4	ENSBTAP00000003533.4

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/APC_C/APC_C	40.80	5.00e-63	237.00	IUUC-Sce-106187

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Bos taurus

Functional Description
(View)

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity).

Protein Sequence
(Fasta)

MTVLQEPVQA AIWQALNHYA YRDAVFLAER LYAEVHSEEA LFLLATCYYR SGKAYKAYRL 60
LKGHSCTTPQ CKYLLAKCCV DLSKLAEGEQ ILSGGVFNKQ KSHDDIVTEF GDSACFTLSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGGCCGGGC CGGAGTCGCT ACGGGGGGGG CCTGAGGCAC TGCAGAAAGT GGGCCTGAAC 60
CTCCAGGATG ACGGTGCTGC AGGAACCCGT CCAGGTAATG GTAACCCTCT TCCCTGAGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0802--TPR repeat
KW-0833--Ubl conjugation pathway

Interpro

IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR001440--TPR_1
IPR019734--TPR_repeat

PROSITE

PS50005--TPR
PS50293--TPR_REGION

Pfam

PF00515--TPR_1
PF13181--TPR_8

SMART

SM00028--TPR

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0005813--C:centrosome
GO:0005737--C:cytoplasm
GO:0005654--C:nucleoplasm
GO:0005876--C:spindle microtubule
GO:0007091--P:metaphase/anaphase transition of mitotic cell cycle
GO:0070979--P:protein K11-linked ubiquitination

KEGG

bta:540660

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000478	Aegilops tauschii	48.72	1.00e-89	324.00
IUUC-Aml-002123	Ailuropoda melanoleuca	98.91	0.00e+00	1662.00
IUUC-Atr-002921	Amborella trichopoda	48.11	2.00e-96	347.00
IUUC-Apl-003652	Anas platyrhynchos	95.18	0.00e+00	1613.00
IUUC-Aca-004797	Anolis carolinensis	92.98	0.00e+00	1489.00
IUUC-Aly-006146	Arabidopsis lyrata	42.22	1.00e-84	307.00
IUUC-Ath-007523	Arabidopsis thaliana	46.69	7.00e-95	341.00
IUUC-Ago-007939	Ashbya gossypii	38.39	1.00e-64	241.00
IUUC-Acl-008169	Aspergillus clavatus	42.98	2.00e-84	306.00
IUUC-Afl-008631	Aspergillus flavus	45.14	1.00e-77	284.00
IUUC-Afu-008990	Aspergillus fumigatus	31.31	5.00e-102	365.00
IUUC-Ani-009208	Aspergillus nidulans	30.56	1.00e-64	241.00
IUUC-Ang-009561	Aspergillus niger	46.39	6.00e-85	308.00
IUUC-Aor-009958	Aspergillus oryzae	45.14	7.00e-77	281.00
IUUC-Ate-010597	Aspergillus terreus	39.95	3.00e-86	313.00
IUUC-Ame-010734	Astyanax mexicanus	79.79	0.00e+00	692.00
IUUC-Bgr-012282	Blumeria graminis	31.72	6.00e-94	338.00
IUUC-Bci-013946	Botrytis cinerea	30.38	6.00e-93	335.00
IUUC-Bdi-014213	Brachypodium distachyon	33.63	2.00e-105	376.00
IUUC-Bol-016307	Brassica oleracea	46.48	1.00e-94	340.00
IUUC-Bra-017042	Brassica rapa	46.39	7.00e-95	341.00
IUUC-Cel-018481	Caenorhabditis elegans	40.51	8.00e-77	281.00
IUUC-Cja-019393	Callithrix jacchus	98.79	0.00e+00	1484.00
IUUC-Cfa-020221	Canis familiaris	99.64	0.00e+00	1677.00
IUUC-Cpo-021792	Cavia porcellus	98.79	0.00e+00	1643.00
IUUC-Csa-023091	Chlorocebus sabaeus	99.03	0.00e+00	1662.00
IUUC-Cin-025231	Ciona intestinalis	47.44	0.00e+00	675.00
IUUC-Csv-025983	Ciona savignyi	44.21	0.00e+00	678.00
IUUC-Cgl-026436	Colletotrichum gloeosporioides	43.17	4.00e-72	266.00
IUUC-Cne-026779	Cryptococcus neoformans	40.75	3.00e-65	243.00
IUUC-Cme-027126	Cyanidioschyzon merolae	36.15	3.00e-62	232.00
IUUC-Dre-028038	Danio rerio	79.71	0.00e+00	1271.00
IUUC-Dno-029681	Dasypus novemcinctus	98.91	0.00e+00	1659.00
IUUC-Dor-030742	Dipodomys ordii	76.92	1.00e-152	533.00
IUUC-Dse-031468	Dothistroma septosporum	35.83	8.00e-65	241.00
IUUC-Dme-031900	Drosophila melanogaster	39.10	1.00e-157	550.00
IUUC-Ete-032396	Echinops telfairi	89.09	0.00e+00	1476.00
IUUC-Eca-034414	Equus caballus	99.64	0.00e+00	1677.00
IUUC-Eeu-034864	Erinaceus europaeus	85.65	0.00e+00	771.00
IUUC-Fca-036459	Felis catus	99.27	0.00e+00	1658.00
IUUC-Fox-037700	Fusarium oxysporum	43.39	2.00e-68	252.00
IUUC-Fso-038112	Fusarium solani	42.63	4.00e-77	282.00
IUUC-Gmo-038876	Gadus morhua	73.63	0.00e+00	1185.00
IUUC-Ggr-039822	Gaeumannomyces graminis	44.05	2.00e-74	274.00
IUUC-Gga-040585	Gallus gallus	94.78	0.00e+00	1587.00
IUUC-Gac-042126	Gasterosteus aculeatus	75.54	0.00e+00	1238.00
IUUC-Gma-044263	Glycine max	32.88	3.00e-112	399.00
IUUC-Ggo-045272	Gorilla gorilla	85.91	0.00e+00	998.00
IUUC-Hsa-045682	Homo sapiens	98.91	0.00e+00	1656.00
IUUC-Hvu-047421	Hordeum vulgare	49.80	2.00e-70	258.00
IUUC-Itr-048133	Ictidomys tridecemlineatus	99.80	0.00e+00	1016.00
IUUC-Kpa-049367	Komagataella pastoris	36.12	2.00e-81	296.00
IUUC-Lch-049755	Latimeria chalumnae	85.11	0.00e+00	1441.00
IUUC-Lpe-051689	Leersia perrieri	32.83	8.00e-106	377.00
IUUC-Loc-052907	Lepisosteus oculatus	85.68	0.00e+00	1358.00
IUUC-Lma-053272	Leptosphaeria maculans	43.12	1.00e-73	271.00
IUUC-Laf-054312	Loxodonta africana	98.56	0.00e+00	1667.00
IUUC-Mcc-055312	Macaca mulatta	99.03	0.00e+00	1662.00
IUUC-Meu-056290	Macropus eugenii	85.82	0.00e+00	1444.00
IUUC-Mpo-057620	Magnaporthe poae	44.05	4.00e-75	276.00
IUUC-Mtr-058302	Medicago truncatula	33.58	4.00e-117	415.00
IUUC-Mla-058835	Melampsora laricipopulina	36.54	1.00e-60	226.00
IUUC-Mga-060010	Meleagris gallopavo	94.61	0.00e+00	1609.00
IUUC-Mvi-060340	Microbotryum violaceum	39.75	9.00e-61	228.00
IUUC-Mmr-060610	Microcebus murinus	98.19	0.00e+00	1632.00
IUUC-Mdo-062216	Monodelphis domestica	96.40	0.00e+00	1640.00
IUUC-Mmu-063476	Mus musculus	97.70	0.00e+00	1655.00
IUUC-Mac-065409	Musa acuminata	45.73	1.00e-94	340.00
IUUC-Mpu-066213	Mustela putorius furo	99.64	0.00e+00	1677.00
IUUC-Mlu-067540	Myotis lucifugus	99.39	0.00e+00	1663.00
IUUC-Nfi-068437	Neosartorya fischeri	38.34	1.00e-85	311.00
IUUC-Ncr-068882	Neurospora crassa	42.94	4.00e-76	279.00
IUUC-Nle-068976	Nomascus leucogenys	98.32	0.00e+00	1656.00
IUUC-Opr-071171	Ochotona princeps	92.38	0.00e+00	780.00
IUUC-Ont-071295	Oreochromis niloticus	74.79	0.00e+00	1227.00
IUUC-Oan-072896	Ornithorhynchus anatinus	95.56	0.00e+00	723.00
IUUC-Ocu-074828	Oryctolagus cuniculus	99.27	0.00e+00	1706.00
IUUC-Oba-075176	Oryza barthii	31.30	8.00e-96	344.00
IUUC-Obr-076622	Oryza brachyantha	33.25	2.00e-114	406.00
IUUC-Ogu-078158	Oryza glumaepatula	33.84	4.00e-110	392.00
IUUC-Oin-079840	Oryza indica	34.85	7.00e-119	421.00
IUUC-Olo-080632	Oryza longistaminata	49.19	1.00e-92	334.00
IUUC-Ome-081193	Oryza meridionalis	34.85	2.00e-118	420.00
IUUC-Oni-082335	Oryza nivara	31.80	6.00e-97	348.00
IUUC-Opu-083857	Oryza punctata	48.43	1.00e-83	303.00
IUUC-Oru-085165	Oryza rufipogon	31.80	1.00e-96	347.00
IUUC-Osa-085529	Oryza sativa	48.62	2.00e-97	348.00
IUUC-Olu-087803	Ostreococcus lucimarinus	47.15	2.00e-87	316.00
IUUC-Oga-088851	Otolemur garnettii	98.41	0.00e+00	1643.00
IUUC-Oar-089794	Ovis aries	99.88	0.00e+00	1677.00
IUUC-Ptr-091588	Pan troglodytes	99.15	0.00e+00	1664.00
IUUC-Pan-092083	Papio anubis	93.21	0.00e+00	1548.00
IUUC-Psi-093368	Pelodiscus sinensis	95.40	0.00e+00	1607.00
IUUC-Pma-094306	Petromyzon marinus	65.40	0.00e+00	1066.00
IUUC-Pno-094898	Phaeosphaeria nodorum	30.56	5.00e-81	295.00
IUUC-Ppa-095288	Physcomitrella patens	48.32	7.00e-104	371.00
IUUC-Pfo-097263	Poecilia formosa	73.13	0.00e+00	1163.00
IUUC-Pab-097782	Pongo abelii	98.79	0.00e+00	1658.00
IUUC-Pca-100771	Procavia capensis	84.50	0.00e+00	1309.00
IUUC-Ppe-102042	Prunus persica	45.97	2.00e-98	353.00
IUUC-Pva-103207	Pteropus vampyrus	99.39	0.00e+00	1677.00
IUUC-Pgr-103352	Puccinia graminis	37.88	1.00e-52	201.00
IUUC-Ptt-103992	Puccinia triticina	39.62	9.00e-29	122.00
IUUC-Pte-104138	Pyrenophora teres	42.41	3.00e-75	276.00
IUUC-Pyt-104652	Pyrenophora triticirepentis	32.03	4.00e-77	282.00
IUUC-Rno-105451	Rattus norvegicus	97.82	0.00e+00	1647.00
IUUC-Sce-106187	Saccharomyces cerevisiae	40.80	2.00e-63	237.00
IUUC-Sha-107398	Sarcophilus harrisii	71.93	0.00e+00	1157.00
IUUC-Sja-107984	Schizosaccharomyces japonicus	43.90	3.00e-75	276.00
IUUC-Spo-108274	Schizosaccharomyces pombe	46.48	1.00e-83	303.00
IUUC-Smo-109678	Selaginella moellendorffii	55.28	2.00e-112	399.00
IUUC-Sit-110813	Setaria italica	32.65	8.00e-110	391.00
IUUC-Sly-111637	Solanum lycopersicum	47.60	7.00e-101	361.00
IUUC-Stu-112086	Solanum tuberosum	47.78	3.00e-98	352.00
IUUC-Sar-113214	Sorex araneus	98.55	0.00e+00	1625.00
IUUC-Sre-114904	Sporisorium reilianum	34.94	5.00e-33	136.00
IUUC-Ssc-115692	Sus scrofa	98.52	0.00e+00	1359.00
IUUC-Tgu-116466	Taeniopygia guttata	94.32	0.00e+00	1576.00
IUUC-Tru-118417	Takifugu rubripes	74.16	0.00e+00	1194.00
IUUC-Tsy-118796	Tarsius syrichta	94.05	0.00e+00	1536.00
IUUC-Tni-120331	Tetraodon nigroviridis	85.99	0.00e+00	663.00
IUUC-Tca-121321	Theobroma cacao	48.47	2.00e-95	343.00
IUUC-Tre-122083	Trichoderma reesei	41.54	1.00e-73	271.00
IUUC-Tvi-122558	Trichoderma virens	41.07	6.00e-73	268.00
IUUC-Tae-125209	Triticum aestivum	33.33	1.00e-108	387.00
IUUC-Tur-126187	Triticum urartu	42.95	3.00e-70	259.00
IUUC-Tme-127012	Tuber melanosporum	31.32	2.00e-97	350.00
IUUC-Tbe-127774	Tupaia belangeri	86.30	0.00e+00	1380.00
IUUC-Ttr-128605	Tursiops truncatus	96.36	0.00e+00	1611.00
IUUC-Uma-129576	Ustilago maydis	33.56	2.00e-32	135.00
IUUC-Vda-129996	Verticillium dahliae	43.08	2.00e-57	215.00
IUUC-Vpa-130122	Vicugna pacos	99.51	0.00e+00	1669.00
IUUC-Vvi-131580	Vitis vinifera	46.65	2.00e-100	360.00
IUUC-Xtr-131756	Xenopus tropicalis	90.05	0.00e+00	1469.00
IUUC-Xma-133214	Xiphophorus maculatus	73.16	0.00e+00	1199.00
IUUC-Yli-134473	Yarrowia lipolytica	42.77	1.00e-74	273.00
IUUC-Zma-135179	Zea mays	32.52	4.00e-114	405.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence