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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Hsa-046370
UUCD1 version UUC-HoS-00969
Ensembl Protein ID ENSP00000359370.3
UniProt Accession Q9NQW1; B7ZM75; Q6MZS3; Q86UF0; Q9Y4Q8; SC31B_HUMAN
Genbank Protein ID AAF78243.1; CAB45735.1; CAE45955.1; CAH73561.1; AAH34946.1; AAI44314.1
Protein Name Protein transport protein Sec31B; SEC31-like protein 2; SEC31-related protein B; SEC31B-1
Genbank Nucleotide ID AF274863; AL080141; BX640914; AL133352; BC034946; BC044569
Gene Name SEC31B; SEC31L2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000075826.16 ENST00000370345.7 ENSP00000359370.3
ENSG00000075826.16 ENST00000479697.5 ENSP00000473995.1
ENSG00000075826.16 ENST00000462434.5 ENSP00000474124.1
ENSG00000075826.16 ENST00000469546.6 ENSP00000435359.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBaseCircNet
miRTarBasemicroRNATRANSFACTargetScan
RepTarSomamiRmiRcodeRAID2
Protein-protein Interaction
IIDiRefIndexHINTMentha
InWeb_IM
Disease-associated Variation
GWASdbOMIM
Post-translational Modifications (PTMs)
dbPAFPhosphositePlus
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.60e-13 51.9 120 152
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf...sdtllvsGsdDgtikvWDlr 31
           Ht+ v++l++   +++ll+sG+ D  i +WDl 
   Q: 120  HTGAVRALDLnpfQGNLLASGASDSEIFIWDLN 152
           9*********997669***************86 PP
   
Organism Homo sapiens
Functional Description
(View)

Functional Description


     As a component of the coat protein complex II (COPII), may function in vesicle budding and cargo export from the endoplasmic reticulum.
 As a component of the coat protein complex II (COPII), may function in vesicle budding and cargo export from the endoplasmic reticulum.
Protein Sequence
(Fasta)
MKLKELERPA VQAWSPASQY PLYLATGTSA QQLDSSFSTN GTLEIFEVDF RDPSLDLKHR 60
GVLSALSRFH KLVWGSFGSG LLESSGVIVG GGDNGMLILY NVTHILSSGK EPVIAQKQKH 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046370|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGCGCCCGGC TCCGCGCGAG AGCCCTGCCA GAGGAGCGGC TCCGGCCGCC GCGCCTGACC 60
CTTGTCCGGG GTCTTCCGCA CAGGTTGGTT CGCCCCGCCG GTCTGGGGTC CCTGGTAGCA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046370|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0256--Endoplasmic reticulum
KW-0931--ER-Golgi transport
KW-0472--Membrane
KW-0621--Polymorphism
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0832--Ubl conjugation
KW-0853--WD repeat
Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
SMART

SM00320--WD40
Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0012507--C:ER to Golgi transport vesicle membrane
GO:0030120--C:vesicle coat
GO:0015031--P:protein transport
GO:0016192--P:vesicle-mediated transport
KEGG hsa:25956
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001690 Ailuropoda melanoleuca 82.92 0.00e+00 1838.00
IUUC-Apl-003403 Anas platyrhynchos 58.67 0.00e+00 1246.00
IUUC-Bta-013361 Bos taurus 84.14 0.00e+00 1839.00
IUUC-Cel-018546 Caenorhabditis elegans 29.27 2.00e-38 154.00
IUUC-Cja-019085 Callithrix jacchus 91.95 0.00e+00 2041.00
IUUC-Cfa-021148 Canis familiaris 82.63 0.00e+00 1783.00
IUUC-Cpo-022389 Cavia porcellus 70.02 0.00e+00 1551.00
IUUC-Csa-023347 Chlorocebus sabaeus 94.67 0.00e+00 2053.00
IUUC-Dor-030341 Dipodomys ordii 75.98 0.00e+00 1466.00
IUUC-Eca-034383 Equus caballus 85.85 0.00e+00 1828.00
IUUC-Eeu-035236 Erinaceus europaeus 78.96 0.00e+00 1621.00
IUUC-Fca-035781 Felis catus 84.38 0.00e+00 1825.00
IUUC-Fal-037298 Ficedula albicollis 57.83 0.00e+00 1225.00
IUUC-Ggo-044594 Gorilla gorilla 96.95 0.00e+00 2135.00
IUUC-Itr-048539 Ictidomys tridecemlineatus 82.73 0.00e+00 1808.00
IUUC-Laf-053384 Loxodonta africana 81.19 0.00e+00 1739.00
IUUC-Mcc-055035 Macaca mulatta 95.08 0.00e+00 2102.00
IUUC-Meu-056451 Macropus eugenii 65.16 2.00e-157 550.00
IUUC-Mga-060086 Meleagris gallopavo 54.84 0.00e+00 1177.00
IUUC-Mdo-062939 Monodelphis domestica 67.81 0.00e+00 1332.00
IUUC-Mmu-064098 Mus musculus 77.50 0.00e+00 1682.00
IUUC-Mpu-066837 Mustela putorius furo 81.24 0.00e+00 1753.00
IUUC-Mlu-067865 Myotis lucifugus 84.41 0.00e+00 1842.00
IUUC-Nle-070089 Nomascus leucogenys 94.15 0.00e+00 2106.00
IUUC-Opr-070212 Ochotona princeps 72.95 0.00e+00 1570.00
IUUC-Oan-073744 Ornithorhynchus anatinus 69.67 0.00e+00 1105.00
IUUC-Ocu-073839 Oryctolagus cuniculus 82.46 0.00e+00 1363.00
IUUC-Oga-088552 Otolemur garnettii 85.92 0.00e+00 1903.00
IUUC-Oar-090193 Ovis aries 82.76 0.00e+00 1806.00
IUUC-Ptr-090462 Pan troglodytes 91.98 0.00e+00 1228.00
IUUC-Pan-092057 Papio anubis 94.92 0.00e+00 2061.00
IUUC-Pab-098721 Pongo abelii 93.81 0.00e+00 2038.00
IUUC-Pca-100606 Procavia capensis 77.25 0.00e+00 1609.00
IUUC-Pva-102315 Pteropus vampyrus 84.58 0.00e+00 1919.00
IUUC-Rno-105108 Rattus norvegicus 76.72 0.00e+00 1494.00
IUUC-Sha-106924 Sarcophilus harrisii 68.16 0.00e+00 1424.00
IUUC-Sar-113151 Sorex araneus 68.10 0.00e+00 863.00
IUUC-Ssc-116348 Sus scrofa 84.31 0.00e+00 1788.00
IUUC-Tgu-116489 Taeniopygia guttata 57.57 0.00e+00 1214.00
IUUC-Tbe-127257 Tupaia belangeri 88.80 0.00e+00 660.00
IUUC-Ttr-129290 Tursiops truncatus 85.42 0.00e+00 879.00
Created Date 25-Jun-2017

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