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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Hsa-046196
UUCD1 version UUC-HoS-00828
Ensembl Protein ID ENSP00000352536.2
UniProt Accession Q8WUA4; D6W557; Q16632; Q9BWI7; TF3C2_HUMAN
Genbank Protein ID BAA02800.1; AAP88801.1; EAX00595.1; EAX00596.1; AAH00212.1; AAH20981.1; AAC09349.1
Protein Name General transcription factor 3C polypeptide 2; TF3C-beta; Transcription factor IIIC 110 kDa subunit; Transcription factor IIIC subunit beta
Genbank Nucleotide ID D13636; BT009799; CH471053; CH471053; BC000212; BC020981; AF054988
Gene Name GTF3C2; KIAA0011
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000115207.13 ENST00000359541.6 ENSP00000352536.2
ENSG00000115207.13 ENST00000457098.5 ENSP00000409043.1
ENSG00000115207.13 ENST00000431028.5 ENSP00000399339.1
ENSG00000115207.13 ENST00000454704.5 ENSP00000393429.1
ENSG00000115207.13 ENST00000415683.2 ENSP00000414422.2
ENSG00000115207.13 ENST00000622534.1 ENSP00000482584.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBaseCircNet
miRTarBasemicroRNATRANSFACTargetScan
RepTarmiRNAMapSomamiRmiRcode
RAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
MenthaInWeb_IM
Disease-associated Variation
GWASdbOMIM
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
HPRDPhospho.ELMUniProtPHOSIDA
BioGRID
DNA Methylation
TCGAICGC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.20e-10 42.1 612 644
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf...sdtllvsGsdDgtikvWDlr 31
           H   v+ l++   ++++lvs++ D +ik WDlr
   Q: 612  HDQAVRTLQWckaNSHFLVSAGSDRKIKFWDLR 644
           8999********8669***************97 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MDTCGVGYVA LGEAGPVGNM TVVDSPGQEV LNQLDVKTSS EMTSAEASVE MSLPTPLPGF 60
EDSPDQRRLP PEQESLSRLE QPDLSSEMSK VSKPRASKPG RKRGGRTRKG PKRPQQPNPP 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046196|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCCTTTTTGA CACTGCAACT CCCATGAGGC CCTGCAGCGT CCCTGGCGCC GCTGAAGACG 60
CCCTGGAACT CGGCTGGCTT CGGAGGGCTC GGTGACTCTG GCCGCGCTGC ATTATGGAAT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046196|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0853--WD repeat
Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0005654--C:nucleoplasm
GO:0000127--C:transcription factor TFIIIC complex
GO:0042791--P:5S class rRNA transcription from RNA polymerase III type 1 promoter
GO:0006383--P:transcription from RNA polymerase III promoter
GO:0006351--P:transcription, DNA-templated
GO:0042797--P:tRNA transcription from RNA polymerase III promoter
KEGG hsa:2976
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000091 Aegilops tauschii 27.59 3.00e-12 68.20
IUUC-Aml-001488 Ailuropoda melanoleuca 94.07 0.00e+00 1541.00
IUUC-Apl-003185 Anas platyrhynchos 63.27 0.00e+00 754.00
IUUC-Aca-005245 Anolis carolinensis 60.68 0.00e+00 725.00
IUUC-Ath-006785 Arabidopsis thaliana 22.12 2.00e-05 45.10
IUUC-Ame-010654 Astyanax mexicanus 43.43 4.00e-146 512.00
IUUC-Bta-012551 Bos taurus 89.06 0.00e+00 1404.00
IUUC-Bdi-014228 Brachypodium distachyon 27.59 2.00e-12 68.90
IUUC-Bol-015619 Brassica oleracea 25.27 1.00e-06 48.50
IUUC-Bra-017820 Brassica rapa 24.73 9.00e-07 49.30
IUUC-Cja-019727 Callithrix jacchus 97.59 0.00e+00 1565.00
IUUC-Cfa-020469 Canis familiaris 93.63 0.00e+00 1476.00
IUUC-Cpo-021854 Cavia porcellus 90.01 0.00e+00 1508.00
IUUC-Csa-023726 Chlorocebus sabaeus 99.12 0.00e+00 1593.00
IUUC-Cho-024296 Choloepus hoffmanni 94.55 0.00e+00 744.00
IUUC-Dre-028735 Danio rerio 40.60 9.00e-159 554.00
IUUC-Dno-028895 Dasypus novemcinctus 91.88 0.00e+00 1425.00
IUUC-Dor-030617 Dipodomys ordii 90.26 0.00e+00 1142.00
IUUC-Eca-033420 Equus caballus 92.54 0.00e+00 1407.00
IUUC-Eeu-035060 Erinaceus europaeus 78.67 0.00e+00 1229.00
IUUC-Fca-035603 Felis catus 92.43 0.00e+00 1449.00
IUUC-Fal-037637 Ficedula albicollis 63.01 0.00e+00 803.00
IUUC-Gga-040991 Gallus gallus 64.98 0.00e+00 797.00
IUUC-Ggo-045595 Gorilla gorilla 99.56 0.00e+00 1619.00
IUUC-Hvu-047758 Hordeum vulgare 26.16 3.00e-12 67.80
IUUC-Itr-048222 Ictidomys tridecemlineatus 93.27 0.00e+00 1225.00
IUUC-Lch-050384 Latimeria chalumnae 46.17 2.00e-150 525.00
IUUC-Lpe-050995 Leersia perrieri 22.16 2.00e-11 65.10
IUUC-Loc-052778 Lepisosteus oculatus 53.54 0.00e+00 701.00
IUUC-Laf-054474 Loxodonta africana 90.58 0.00e+00 1288.00
IUUC-Mcc-055795 Macaca mulatta 88.00 0.00e+00 1438.00
IUUC-Mga-059757 Meleagris gallopavo 80.00 1.00e-101 361.00
IUUC-Mmr-061702 Microcebus murinus 94.21 0.00e+00 1357.00
IUUC-Mdo-063012 Monodelphis domestica 71.98 0.00e+00 1083.00
IUUC-Mmu-063858 Mus musculus 82.29 0.00e+00 1410.00
IUUC-Mpu-066147 Mustela putorius furo 89.25 0.00e+00 1395.00
IUUC-Mlu-067530 Myotis lucifugus 91.55 0.00e+00 1392.00
IUUC-Nle-069278 Nomascus leucogenys 99.12 0.00e+00 1588.00
IUUC-Opr-070222 Ochotona princeps 95.21 0.00e+00 1180.00
IUUC-Ont-071367 Oreochromis niloticus 40.44 8.00e-131 461.00
IUUC-Oan-073357 Ornithorhynchus anatinus 78.69 0.00e+00 733.00
IUUC-Ocu-074887 Oryctolagus cuniculus 90.79 0.00e+00 1398.00
IUUC-Obr-076376 Oryza brachyantha 24.14 7.00e-13 69.70
IUUC-Ogl-077258 Oryza glaberrima 25.81 9.00e-10 59.70
IUUC-Ogu-078002 Oryza glumaepatula 30.71 8.00e-10 59.30
IUUC-Oin-079689 Oryza indica 25.81 8.00e-10 60.10
IUUC-Olo-080486 Oryza longistaminata 29.66 1.00e-07 52.00
IUUC-Oni-082369 Oryza nivara 25.81 9.00e-10 59.70
IUUC-Opu-083230 Oryza punctata 25.27 5.00e-10 60.50
IUUC-Osa-085403 Oryza sativa 25.81 7.00e-10 59.70
IUUC-Ola-087512 Oryzias latipes 41.48 7.00e-74 270.00
IUUC-Oga-088051 Otolemur garnettii 91.78 0.00e+00 1385.00
IUUC-Oar-090076 Ovis aries 88.84 0.00e+00 1424.00
IUUC-Ptr-091503 Pan troglodytes 99.13 0.00e+00 1396.00
IUUC-Pan-092123 Papio anubis 99.23 0.00e+00 1594.00
IUUC-Psi-094020 Pelodiscus sinensis 65.80 0.00e+00 839.00
IUUC-Pma-094395 Petromyzon marinus 43.79 2.00e-83 302.00
IUUC-Ppa-095644 Physcomitrella patens 26.50 6.00e-11 62.00
IUUC-Pfo-097023 Poecilia formosa 41.20 2.00e-126 446.00
IUUC-Pab-097532 Pongo abelii 99.12 0.00e+00 1606.00
IUUC-Pop-099342 Populus trichocarpa 20.82 3.00e-10 60.80
IUUC-Pca-100255 Procavia capensis 91.93 0.00e+00 734.00
IUUC-Ppe-101268 Prunus persica 28.70 4.00e-08 54.30
IUUC-Pva-102403 Pteropus vampyrus 93.41 0.00e+00 1424.00
IUUC-Rno-105329 Rattus norvegicus 83.54 0.00e+00 1415.00
IUUC-Sha-106857 Sarcophilus harrisii 76.94 0.00e+00 1023.00
IUUC-Sit-110532 Setaria italica 31.50 4.00e-12 67.80
IUUC-Sly-110922 Solanum lycopersicum 24.39 4.00e-10 60.50
IUUC-Sar-113690 Sorex araneus 83.20 1.00e-178 620.00
IUUC-Sbi-114680 Sorghum bicolor 33.07 7.00e-13 70.50
IUUC-Tgu-117058 Taeniopygia guttata 69.82 2.00e-144 505.00
IUUC-Tru-118675 Takifugu rubripes 43.67 2.00e-143 503.00
IUUC-Tsy-119606 Tarsius syrichta 86.32 0.00e+00 951.00
IUUC-Tni-120125 Tetraodon nigroviridis 41.18 7.00e-84 304.00
IUUC-Tae-125334 Triticum aestivum 24.11 2.00e-12 68.60
IUUC-Tur-126862 Triticum urartu 27.59 2.00e-12 68.60
IUUC-Tbe-127727 Tupaia belangeri 83.61 0.00e+00 1174.00
IUUC-Ttr-128425 Tursiops truncatus 92.82 0.00e+00 1168.00
IUUC-Vpa-130050 Vicugna pacos 89.46 0.00e+00 1380.00
IUUC-Vvi-131706 Vitis vinifera 24.06 4.00e-09 57.40
IUUC-Xtr-132178 Xenopus tropicalis 46.84 0.00e+00 701.00
Created Date 25-Jun-2017

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