iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mtr-058310

Ensembl Protein ID

KEH28771

UniProt Accession

A0A072UH84; A0A072UH84_MEDTR

Genbank Protein ID

KEH28771.1

Protein Name

Coatomer subunit beta'

Genbank Nucleotide ID

CM001220

Gene Name

MTR_4g011950

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MTR_4g011950	KEH28771	KEH28771

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.30e-35	120.5	184	224
UBD/Beta-Prp	1.70e-66	225.9	14	290

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           H+ +v+c+++    d ++l++GsdD+t kvWD+ t  ++++
   Q: 184  HQKGVNCVDYftgGDkPYLITGSDDHTAKVWDYQTKSCVQT 224
           999*****966*9778*******************999986 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdkl 109
           +++++++v+ +p +++++++ ++gt+ +w+++++++ +s++  e +v++ kf+ ++++ v g++D++i+v++++t + v ++++h+d++++++++p+  ++
   Q: 14   RSERVKSVDLHPTEPWILASLYSGTVCIWNYQSQTMAKSFEVTELPVRSAKFIARKQWVVAGADDMFIRVYNYNTMDKVKVFEAHSDYIRCVAVHPTLPYV 114
           5678999********************************************************************************************** PP
   S: 110  vsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvysls..fdsngkelvsgsldgtvklw 207
           +s s+d  i++wd+e+g+   ++++gh++ v+ v+++p++ n ++s+slDrt+++W+l + +   tl   h++ v++++     ++++l++gs+d t k+w
   Q: 115  LSSSDDMLIKLWDWEKGWICTQIFEGHSHYVMQVTFNPKDtNTFASASLDRTIKIWNLGSPDPNFTLDA-HQKGVNCVDyfTGGDKPYLITGSDDHTAKVW 214
           ******************9999*********************************************98.*********6444555*************** PP
   S: 208  dlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlg 283
           d+qt++cv+tl ght nv+ v f+p+  ++++gs+Dg++riW +++  l +tl++  ++v+++ +++ +++v++  
   Q: 215  DYQTKSCVQTLDGHTHNVSAVCFHPELPIIITGSEDGTVRIWHSTTYRLENTLNYGLERVWAIGYMKGSRRVVIGY 290
           ***************************************************************9966666666433 PP

Organism

Medicago truncatula

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MPLRLEIKRK LAQRSERVKS VDLHPTEPWI LASLYSGTVC IWNYQSQTMA KSFEVTELPV 60
RSAKFIARKQ WVVAGADDMF IRVYNYNTMD KVKVFEAHSD YIRCVAVHPT LPYVLSSSDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCTTGTGAA CCAAACACAC TTTTAATTAA AAATATCTCC CCTCCACTCC CCTCCGTAAA 60
AATCCCTCCC CTCCCCTCCT AATTCTCGAA CCAAACGGAT CGAGAGTGTG ATGACTCACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030663--C:COPI-coated vesicle membrane
GO:0000139--C:Golgi membrane
GO:0030117--C:membrane coat
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

KEGG

mtr:MTR_4g011950

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002154	Ailuropoda melanoleuca	62.67	0.00e+00	1125.00
IUUC-Apl-003976	Anas platyrhynchos	62.42	0.00e+00	1127.00
IUUC-Aca-004301	Anolis carolinensis	62.47	0.00e+00	1129.00
IUUC-Ago-007914	Ashbya gossypii	46.98	0.00e+00	726.00
IUUC-Acl-008237	Aspergillus clavatus	52.67	0.00e+00	906.00
IUUC-Afl-008535	Aspergillus flavus	53.34	0.00e+00	861.00
IUUC-Afu-008845	Aspergillus fumigatus	52.86	0.00e+00	895.00
IUUC-Ani-009135	Aspergillus nidulans	54.28	0.00e+00	886.00
IUUC-Ang-009654	Aspergillus niger	56.97	0.00e+00	819.00
IUUC-Aor-009939	Aspergillus oryzae	52.36	0.00e+00	920.00
IUUC-Ate-010355	Aspergillus terreus	52.43	0.00e+00	883.00
IUUC-Ame-010922	Astyanax mexicanus	56.82	0.00e+00	981.00
IUUC-Bgr-012249	Blumeria graminis	52.83	0.00e+00	899.00
IUUC-Bta-013579	Bos taurus	62.38	0.00e+00	979.00
IUUC-Bci-013866	Botrytis cinerea	53.12	0.00e+00	899.00
IUUC-Cel-018387	Caenorhabditis elegans	53.83	0.00e+00	982.00
IUUC-Cja-019145	Callithrix jacchus	62.59	0.00e+00	1126.00
IUUC-Cfa-020564	Canis familiaris	62.71	0.00e+00	1129.00
IUUC-Cpo-022201	Cavia porcellus	62.67	0.00e+00	1125.00
IUUC-Csa-023383	Chlorocebus sabaeus	65.61	0.00e+00	838.00
IUUC-Cho-024454	Choloepus hoffmanni	59.16	0.00e+00	934.00
IUUC-Cin-025681	Ciona intestinalis	59.08	0.00e+00	997.00
IUUC-Csv-026012	Ciona savignyi	58.35	0.00e+00	974.00
IUUC-Cgl-026649	Colletotrichum gloeosporioides	49.14	0.00e+00	806.00
IUUC-Cne-026986	Cryptococcus neoformans	50.00	0.00e+00	872.00
IUUC-Cme-027219	Cyanidioschyzon merolae	49.94	0.00e+00	890.00
IUUC-Dre-027846	Danio rerio	62.76	0.00e+00	1131.00
IUUC-Dor-030462	Dipodomys ordii	59.82	0.00e+00	862.00
IUUC-Dse-031268	Dothistroma septosporum	52.62	0.00e+00	890.00
IUUC-Dme-031791	Drosophila melanogaster	57.48	0.00e+00	1015.00
IUUC-Ete-033166	Echinops telfairi	58.39	0.00e+00	707.00
IUUC-Eca-034180	Equus caballus	61.14	0.00e+00	1082.00
IUUC-Eeu-035086	Erinaceus europaeus	51.74	2.00e-128	453.00
IUUC-Fca-036265	Felis catus	62.71	0.00e+00	1127.00
IUUC-Fal-037202	Ficedula albicollis	61.86	0.00e+00	1078.00
IUUC-Fox-037711	Fusarium oxysporum	53.86	0.00e+00	863.00
IUUC-Fso-038268	Fusarium solani	53.22	0.00e+00	870.00
IUUC-Gmo-039046	Gadus morhua	62.03	0.00e+00	1115.00
IUUC-Ggr-039863	Gaeumannomyces graminis	52.70	0.00e+00	884.00
IUUC-Gga-041112	Gallus gallus	63.08	0.00e+00	1134.00
IUUC-Gac-041733	Gasterosteus aculeatus	61.67	0.00e+00	1086.00
IUUC-Gma-042910	Glycine max	93.06	0.00e+00	1760.00
IUUC-Ggo-044984	Gorilla gorilla	62.59	0.00e+00	1127.00
IUUC-Hsa-046698	Homo sapiens	62.47	0.00e+00	1127.00
IUUC-Hvu-047669	Hordeum vulgare	90.68	0.00e+00	699.00
IUUC-Itr-048212	Ictidomys tridecemlineatus	62.67	0.00e+00	1123.00
IUUC-Kpa-049265	Komagataella pastoris	51.02	0.00e+00	843.00
IUUC-Lch-050473	Latimeria chalumnae	62.76	0.00e+00	1129.00
IUUC-Loc-052675	Lepisosteus oculatus	61.66	0.00e+00	1133.00
IUUC-Lma-053218	Leptosphaeria maculans	51.95	0.00e+00	868.00
IUUC-Laf-053757	Loxodonta africana	62.64	0.00e+00	1123.00
IUUC-Mcc-054859	Macaca mulatta	62.59	0.00e+00	1126.00
IUUC-Meu-056174	Macropus eugenii	55.74	6.00e-114	404.00
IUUC-Mor-057264	Magnaporthe oryzae	53.19	0.00e+00	873.00
IUUC-Mpo-057538	Magnaporthe poae	52.45	0.00e+00	888.00
IUUC-Mla-058937	Melampsora laricipopulina	53.28	0.00e+00	900.00
IUUC-Mga-059875	Meleagris gallopavo	62.80	0.00e+00	1130.00
IUUC-Mvi-060240	Microbotryum violaceum	50.45	0.00e+00	905.00
IUUC-Mmr-061261	Microcebus murinus	62.71	0.00e+00	1128.00
IUUC-Mdo-062076	Monodelphis domestica	62.95	0.00e+00	1135.00
IUUC-Mmu-063324	Mus musculus	62.59	0.00e+00	1128.00
IUUC-Mpu-065961	Mustela putorius furo	62.71	0.00e+00	1127.00
IUUC-Mlu-067059	Myotis lucifugus	61.99	0.00e+00	1108.00
IUUC-Nfi-068277	Neosartorya fischeri	52.69	0.00e+00	884.00
IUUC-Ncr-068659	Neurospora crassa	53.18	0.00e+00	904.00
IUUC-Nle-069034	Nomascus leucogenys	62.59	0.00e+00	1127.00
IUUC-Opr-070334	Ochotona princeps	63.23	0.00e+00	1016.00
IUUC-Ont-071563	Oreochromis niloticus	62.39	0.00e+00	1123.00
IUUC-Oan-073416	Ornithorhynchus anatinus	61.98	0.00e+00	1068.00
IUUC-Ocu-074522	Oryctolagus cuniculus	62.71	0.00e+00	1124.00
IUUC-Ola-087245	Oryzias latipes	62.11	0.00e+00	1121.00
IUUC-Oga-088163	Otolemur garnettii	60.29	0.00e+00	1068.00
IUUC-Oar-089842	Ovis aries	62.71	0.00e+00	1128.00
IUUC-Ptr-090501	Pan troglodytes	62.59	0.00e+00	1127.00
IUUC-Pan-092011	Papio anubis	62.59	0.00e+00	1127.00
IUUC-Psi-093308	Pelodiscus sinensis	62.95	0.00e+00	1132.00
IUUC-Pma-094695	Petromyzon marinus	59.07	0.00e+00	988.00
IUUC-Pno-094785	Phaeosphaeria nodorum	58.08	2.00e-103	369.00
IUUC-Pfo-096587	Poecilia formosa	62.27	0.00e+00	1125.00
IUUC-Pab-097926	Pongo abelii	60.86	0.00e+00	1054.00
IUUC-Pca-100965	Procavia capensis	61.82	0.00e+00	1092.00
IUUC-Pva-102451	Pteropus vampyrus	58.77	0.00e+00	855.00
IUUC-Pgr-103453	Puccinia graminis	53.11	0.00e+00	901.00
IUUC-Ptt-103868	Puccinia triticina	53.06	0.00e+00	899.00
IUUC-Pte-104274	Pyrenophora teres	53.11	0.00e+00	899.00
IUUC-Pyt-104794	Pyrenophora triticirepentis	52.28	0.00e+00	846.00
IUUC-Rno-105979	Rattus norvegicus	53.58	0.00e+00	827.00
IUUC-Sce-106269	Saccharomyces cerevisiae	47.68	0.00e+00	760.00
IUUC-Sha-106905	Sarcophilus harrisii	62.83	0.00e+00	1132.00
IUUC-Sja-107838	Schizosaccharomyces japonicus	46.65	0.00e+00	777.00
IUUC-Spo-108299	Schizosaccharomyces pombe	46.72	0.00e+00	804.00
IUUC-Smo-108828	Selaginella moellendorffii	80.76	0.00e+00	1408.00
IUUC-Sar-113472	Sorex araneus	57.42	0.00e+00	768.00
IUUC-Sre-115040	Sporisorium reilianum	53.46	0.00e+00	908.00
IUUC-Ssc-115593	Sus scrofa	62.59	0.00e+00	1127.00
IUUC-Tgu-117239	Taeniopygia guttata	62.67	0.00e+00	1130.00
IUUC-Tru-118025	Takifugu rubripes	62.08	0.00e+00	1121.00
IUUC-Tsy-118824	Tarsius syrichta	58.57	0.00e+00	798.00
IUUC-Tni-120142	Tetraodon nigroviridis	61.99	0.00e+00	1115.00
IUUC-Tre-122072	Trichoderma reesei	52.70	0.00e+00	896.00
IUUC-Tvi-122546	Trichoderma virens	51.84	0.00e+00	872.00
IUUC-Tme-127041	Tuber melanosporum	52.82	0.00e+00	908.00
IUUC-Tbe-127770	Tupaia belangeri	61.35	0.00e+00	900.00
IUUC-Ttr-129294	Tursiops truncatus	62.47	0.00e+00	1125.00
IUUC-Uma-129351	Ustilago maydis	51.64	0.00e+00	892.00
IUUC-Vda-129716	Verticillium dahliae	52.63	0.00e+00	904.00
IUUC-Vpa-130037	Vicugna pacos	52.05	2.00e-132	466.00
IUUC-Xtr-132633	Xenopus tropicalis	62.35	0.00e+00	1124.00
IUUC-Xma-133347	Xiphophorus maculatus	62.52	0.00e+00	1127.00
IUUC-Yli-134455	Yarrowia lipolytica	50.63	0.00e+00	816.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence