iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
FBgn0002932	FBtr0082002	FBpp0081480
FBgn0002932	FBtr0300414	FBpp0289643
FBgn0002932	FBtr0082004	FBpp0081482
FBgn0002932	FBtr0082003	FBpp0081481

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Protein 3D Structure
PDB	MMDB
Post-translational Modifications (PTMs)
dbPAF	dbPTM	Phospho.ELM	UniProt
PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/RING	RING	19580805

Classification

Family	E-value	Score	Start	End
E3 activity/RING/RING	3.80e-05	24.2	701	742

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgH.vfhadCl.qkwpglknssskefrCPlCr 46
           C iC+e + d  ++  CgH +++ dC  ++w        +  +CPlCr
   Q: 701  CTICYENPID-SVLYMCGHmCMCYDCAiEQW-----RGVGGGQCPLCR 742
           ********9*.67688***889****66***.....5667777****8 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MGLSDIPANY MQGSHPHLTL HPQQQHHQNQ QHLQHLQQMQ QLHNAMPTPA QQAAQVLAME 60
SNELLMSTKD KLSSKKKMHL LKKIKKRFGL VRRSPSSCPG PNNLPPLQFH SVHGDNIRIS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAATACTAAC GCGGTCACAC TAAAAAAAAG CCTTGCGACC GGCAGCTCCA TCCAAATAAC 60
AATTAGGCAA AGCTTTAAAA TGCATCGCAT TTAACGCCTA TGATTCCGGA AGTGAGCTAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0002--3D-structure
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0221--Differentiation
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0524--Neurogenesis
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR006573--NHR_dom
IPR001841--Znf_RING

PROSITE

PS51065--NHR
PS50089--ZF_RING_2

Pfam

PF07177--Neuralized

SMART

SM00588--NEUZ
SM00184--RING

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0003677--F:DNA binding
GO:1901981--F:phosphatidylinositol phosphate binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0008356--P:asymmetric cell division
GO:0048854--P:brain morphogenesis
GO:0048749--P:compound eye development
GO:0007398--P:ectoderm development
GO:0030718--P:germ-line stem cell population maintenance
GO:0007476--P:imaginal disc-derived wing morphogenesis
GO:0002121--P:inter-male aggressive behavior
GO:0046331--P:lateral inhibition
GO:0031987--P:locomotion involved in locomotory behavior
GO:0007616--P:long-term memory
GO:0007498--P:mesoderm development
GO:0035204--P:negative regulation of lamellocyte differentiation
GO:0007399--P:nervous system development
GO:0007219--P:Notch signaling pathway
GO:0042048--P:olfactory behavior
GO:0030707--P:ovarian follicle cell development
GO:0007422--P:peripheral nervous system development
GO:0045747--P:positive regulation of Notch signaling pathway
GO:0051260--P:protein homooligomerization
GO:0008104--P:protein localization
GO:0000209--P:protein polyubiquitination
GO:0045314--P:regulation of compound eye photoreceptor development
GO:0008593--P:regulation of Notch signaling pathway
GO:0046532--P:regulation of photoreceptor cell differentiation
GO:0007423--P:sensory organ development
GO:0016360--P:sensory organ precursor cell fate determination
GO:0001964--P:startle response
GO:0007419--P:ventral cord development

KEGG

dme:Dmel_CG11988

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000777	Aegilops tauschii	59.62	8.00e-14	72.00
IUUC-Aml-002324	Ailuropoda melanoleuca	37.91	4.00e-32	131.00
IUUC-Atr-002944	Amborella trichopoda	56.60	5.00e-13	69.30
IUUC-Apl-003920	Anas platyrhynchos	35.21	2.00e-66	246.00
IUUC-Aca-005343	Anolis carolinensis	34.25	8.00e-56	210.00
IUUC-Aly-006153	Arabidopsis lyrata	52.63	6.00e-13	68.90
IUUC-Ath-006731	Arabidopsis thaliana	54.39	1.00e-13	71.20
IUUC-Ame-010891	Astyanax mexicanus	41.51	1.00e-33	137.00
IUUC-Bta-013255	Bos taurus	39.58	3.00e-31	129.00
IUUC-Bdi-014456	Brachypodium distachyon	43.10	6.00e-10	58.50
IUUC-Bol-016275	Brassica oleracea	56.60	1.00e-13	71.20
IUUC-Bra-017715	Brassica rapa	56.60	1.00e-13	71.20
IUUC-Cja-019314	Callithrix jacchus	38.06	2.00e-32	133.00
IUUC-Cfa-021151	Canis familiaris	38.06	1.00e-32	133.00
IUUC-Cpo-022395	Cavia porcellus	30.30	3.00e-48	185.00
IUUC-Csa-024268	Chlorocebus sabaeus	33.81	5.00e-57	214.00
IUUC-Cho-025082	Choloepus hoffmanni	38.56	7.00e-32	130.00
IUUC-Cin-025529	Ciona intestinalis	30.36	6.00e-54	204.00
IUUC-Csv-026316	Ciona savignyi	40.61	5.00e-37	147.00
IUUC-Dre-028687	Danio rerio	41.36	2.00e-33	136.00
IUUC-Dno-029754	Dasypus novemcinctus	38.06	1.00e-32	133.00
IUUC-Dor-030366	Dipodomys ordii	38.06	1.00e-32	133.00
IUUC-Eca-034278	Equus caballus	32.57	5.00e-16	76.60
IUUC-Fca-035976	Felis catus	37.66	1.00e-31	130.00
IUUC-Fal-036894	Ficedula albicollis	34.20	6.00e-65	240.00
IUUC-Gmo-038673	Gadus morhua	45.21	1.00e-31	130.00
IUUC-Gga-041040	Gallus gallus	34.27	2.00e-65	242.00
IUUC-Gac-042143	Gasterosteus aculeatus	44.87	2.00e-32	132.00
IUUC-Gma-043468	Glycine max	60.38	2.00e-15	77.80
IUUC-Ggo-045648	Gorilla gorilla	38.06	8.00e-33	134.00
IUUC-Hsa-046831	Homo sapiens	38.06	1.00e-32	133.00
IUUC-Hvu-047768	Hordeum vulgare	55.77	8.00e-13	68.20
IUUC-Itr-048936	Ictidomys tridecemlineatus	37.21	1.00e-33	135.00
IUUC-Lch-049591	Latimeria chalumnae	35.53	5.00e-61	228.00
IUUC-Lpe-051170	Leersia perrieri	40.68	3.00e-10	59.30
IUUC-Loc-052110	Lepisosteus oculatus	40.76	2.00e-33	135.00
IUUC-Laf-054262	Loxodonta africana	38.06	9.00e-33	134.00
IUUC-Mcc-055333	Macaca mulatta	38.06	2.00e-32	133.00
IUUC-Meu-056023	Macropus eugenii	40.76	4.00e-35	142.00
IUUC-Mtr-058048	Medicago truncatula	58.49	1.00e-14	74.30
IUUC-Mga-059732	Meleagris gallopavo	34.68	2.00e-59	222.00
IUUC-Mdo-061835	Monodelphis domestica	33.80	2.00e-60	226.00
IUUC-Mmu-063122	Mus musculus	32.43	1.00e-57	216.00
IUUC-Mac-064492	Musa acuminata	56.60	8.00e-14	71.60
IUUC-Mpu-066321	Mustela putorius furo	28.05	5.00e-45	174.00
IUUC-Mlu-067385	Myotis lucifugus	36.47	2.00e-31	129.00
IUUC-Nle-069399	Nomascus leucogenys	32.90	5.00e-24	103.00
IUUC-Opr-070822	Ochotona princeps	38.06	4.00e-33	135.00
IUUC-Ont-072255	Oreochromis niloticus	45.86	2.00e-33	136.00
IUUC-Oan-073429	Ornithorhynchus anatinus	31.59	1.00e-56	213.00
IUUC-Ocu-074215	Oryctolagus cuniculus	38.71	4.00e-32	132.00
IUUC-Oba-075400	Oryza barthii	44.23	3.00e-10	59.30
IUUC-Obr-076257	Oryza brachyantha	40.68	2.00e-10	59.70
IUUC-Ogl-077249	Oryza glaberrima	44.23	3.00e-10	59.70
IUUC-Ogu-078361	Oryza glumaepatula	54.72	9.00e-13	68.20
IUUC-Oin-080213	Oryza indica	44.23	4.00e-10	59.30
IUUC-Olo-080683	Oryza longistaminata	44.23	7.00e-10	58.20
IUUC-Ome-081372	Oryza meridionalis	58.33	4.00e-11	62.80
IUUC-Oni-082539	Oryza nivara	44.23	3.00e-10	59.30
IUUC-Opu-083730	Oryza punctata	54.72	9.00e-13	68.20
IUUC-Oru-084786	Oryza rufipogon	44.23	3.00e-10	59.70
IUUC-Osa-085344	Oryza sativa	44.23	3.00e-10	60.10
IUUC-Ola-086439	Oryzias latipes	46.98	4.00e-34	138.00
IUUC-Oga-088419	Otolemur garnettii	36.72	8.00e-33	134.00
IUUC-Oar-090002	Ovis aries	38.22	3.00e-32	132.00
IUUC-Ptr-091650	Pan troglodytes	38.06	1.00e-32	133.00
IUUC-Pan-092859	Papio anubis	43.42	3.00e-27	115.00
IUUC-Psi-092984	Pelodiscus sinensis	41.40	1.00e-35	144.00
IUUC-Ppa-095704	Physcomitrella patens	50.00	4.00e-11	62.80
IUUC-Pfo-097341	Poecilia formosa	45.40	7.00e-36	144.00
IUUC-Pab-097779	Pongo abelii	33.33	6.00e-58	217.00
IUUC-Pop-099007	Populus trichocarpa	58.49	5.00e-14	72.80
IUUC-Pca-100160	Procavia capensis	40.99	1.00e-33	137.00
IUUC-Ppe-102105	Prunus persica	58.49	7.00e-14	72.00
IUUC-Pva-102531	Pteropus vampyrus	38.06	2.00e-32	132.00
IUUC-Rno-105206	Rattus norvegicus	31.97	3.00e-57	215.00
IUUC-Sha-107468	Sarcophilus harrisii	33.88	1.00e-60	226.00
IUUC-Smo-108729	Selaginella moellendorffii	47.46	3.00e-10	59.70
IUUC-Sit-110065	Setaria italica	46.00	1.00e-09	57.80
IUUC-Sly-111517	Solanum lycopersicum	57.69	6.00e-15	75.90
IUUC-Stu-112045	Solanum tuberosum	58.49	4.00e-14	72.80
IUUC-Sbi-114634	Sorghum bicolor	56.60	8.00e-13	68.20
IUUC-Tgu-116692	Taeniopygia guttata	34.44	3.00e-65	241.00
IUUC-Tru-118732	Takifugu rubripes	45.58	2.00e-33	136.00
IUUC-Tni-120907	Tetraodon nigroviridis	44.44	1.00e-33	137.00
IUUC-Tca-121136	Theobroma cacao	42.86	7.00e-14	72.00
IUUC-Tae-124586	Triticum aestivum	33.86	1.00e-13	70.90
IUUC-Tur-126820	Triticum urartu	41.57	6.00e-15	71.60
IUUC-Tbe-127614	Tupaia belangeri	42.45	1.00e-24	107.00
IUUC-Ttr-128919	Tursiops truncatus	37.91	5.00e-32	131.00
IUUC-Vpa-130273	Vicugna pacos	37.91	2.00e-31	129.00
IUUC-Vvi-131271	Vitis vinifera	58.49	9.00e-14	71.60
IUUC-Xtr-132312	Xenopus tropicalis	43.23	2.00e-37	149.00
IUUC-Xma-134204	Xiphophorus maculatus	45.40	1.00e-35	144.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence