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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Cel-018345
Ensembl Protein ID F32G8.6
UniProt Accession Q19980; GCH1_CAEEL
Genbank Protein ID CAA96650.1
Protein Name GTP cyclohydrolase 1; GTP cyclohydrolase I
Genbank Nucleotide ID Z72509
Gene Name cat-4; F32G8.6
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
WBGene00000298 F32G8.6 F32G8.6
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNARAID2
Protein-protein Interaction
IIDiRefIndexPINAMentha
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
UBD/Other/Other 71.74 4.00e-79 291.00 IUUC-Hsa-046907
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Caenorhabditis elegans
Functional Description
(View)

Functional Description


     Toroid-shaped homodecamer, composed of two pentamers of five dimers.
 Toroid-shaped homodecamer, composed of two pentamers of five dimers.
Protein Sequence
(Fasta)
MSRIENESGF LSSDAASVGS EDDKVEMKKR NGTIPKEDHL KSMCNAYQSI IQHVGEDINR 60
QGLLKTPERA AKAMMAFTKG YDDQLDELLN EAVFDEDHDE MVIVKDIEMF SLCEHHLVPF 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cel-018345|UBD,UBD/Other/Other|Caenorhabditis elegans
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGGCTTTACC CACTCTATCA ACATCATAAT ATCAAAATGT CCAGAATTGA GAACGAAAGC 60
GGATTTTTGT CATCTGACGC CGCAAGTGTT GGATCCGAAG ACGATAAAGT TGAGATGAAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cel-018345|UBD,UBD/Other/Other|Caenorhabditis elegans
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0021--Allosteric enzyme
KW-0181--Complete proteome
KW-0342--GTP-binding
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0783--Tetrahydrobiopterin biosynthesis
KW-0862--Zinc
Interpro

IPR001474--GTP_CycHdrlase_I
IPR018234--GTP_CycHdrlase_I_CS
IPR020602--GTP_CycHdrlase_I_dom
PROSITE

PS00859--GTP_CYCLOHYDROL_1_1
PS00860--GTP_CYCLOHYDROL_1_2
Pfam

PF01227--GTP_cyclohydroI
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005525--F:GTP binding
GO:0003934--F:GTP cyclohydrolase I activity
GO:0046872--F:metal ion binding
GO:0035998--P:7,8-dihydroneopterin 3'-triphosphate biosynthetic process
GO:0006585--P:dopamine biosynthetic process from tyrosine
GO:0042438--P:melanin biosynthetic process
GO:0006729--P:tetrahydrobiopterin biosynthetic process
GO:0046654--P:tetrahydrofolate biosynthetic process
KEGG cel:CELE_F32G8.6
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Atr-002530 Amborella trichopoda 35.47 3.00e-29 122.00
IUUC-Apl-004135 Anas platyrhynchos 71.20 7.00e-77 278.00
IUUC-Aca-005252 Anolis carolinensis 72.53 1.00e-77 280.00
IUUC-Aly-006454 Arabidopsis lyrata 38.34 1.00e-28 119.00
IUUC-Ath-006744 Arabidopsis thaliana 38.38 5.00e-28 117.00
IUUC-Ago-007744 Ashbya gossypii 69.49 1.00e-72 264.00
IUUC-Acl-008058 Aspergillus clavatus 63.64 2.00e-73 268.00
IUUC-Afl-008668 Aspergillus flavus 64.71 2.00e-74 271.00
IUUC-Afu-008935 Aspergillus fumigatus 63.64 2.00e-73 267.00
IUUC-Ani-009207 Aspergillus nidulans 61.11 3.00e-73 266.00
IUUC-Ang-009686 Aspergillus niger 65.22 1.00e-73 268.00
IUUC-Aor-010202 Aspergillus oryzae 64.71 2.00e-74 271.00
IUUC-Ate-010518 Aspergillus terreus 64.17 1.00e-73 268.00
IUUC-Ame-010958 Astyanax mexicanus 71.74 1.00e-79 287.00
IUUC-Bgr-012060 Blumeria graminis 58.24 3.00e-65 240.00
IUUC-Bta-012416 Bos taurus 69.23 3.00e-81 293.00
IUUC-Bci-013811 Botrytis cinerea 56.45 5.00e-65 239.00
IUUC-Bdi-014794 Brachypodium distachyon 41.04 9.00e-25 106.00
IUUC-Bol-015182 Brassica oleracea 39.78 6.00e-30 124.00
IUUC-Bra-016764 Brassica rapa 39.67 5.00e-29 120.00
IUUC-Cja-019848 Callithrix jacchus 77.94 1.00e-64 236.00
IUUC-Cfa-020630 Canis familiaris 72.28 4.00e-81 293.00
IUUC-Cpo-021420 Cavia porcellus 76.05 9.00e-78 281.00
IUUC-Cre-022618 Chlamydomonas reinhardtii 40.10 8.00e-37 145.00
IUUC-Csa-023403 Chlorocebus sabaeus 68.07 1.00e-63 234.00
IUUC-Cho-024907 Choloepus hoffmanni 72.83 1.00e-81 294.00
IUUC-Cin-025120 Ciona intestinalis 75.71 2.00e-74 270.00
IUUC-Csv-026259 Ciona savignyi 74.03 1.00e-82 296.00
IUUC-Cgl-026508 Colletotrichum gloeosporioides 59.12 5.00e-65 239.00
IUUC-Cne-026810 Cryptococcus neoformans 64.86 3.00e-71 261.00
IUUC-Cme-027139 Cyanidioschyzon merolae 50.54 2.00e-51 194.00
IUUC-Dre-028815 Danio rerio 64.06 4.00e-80 289.00
IUUC-Dno-029017 Dasypus novemcinctus 75.57 2.00e-81 293.00
IUUC-Dor-030417 Dipodomys ordii 79.70 1.00e-64 236.00
IUUC-Dse-031187 Dothistroma septosporum 63.45 2.00e-74 270.00
IUUC-Dme-031615 Drosophila melanogaster 73.40 2.00e-72 263.00
IUUC-Ete-032727 Echinops telfairi 49.32 7.00e-35 139.00
IUUC-Eca-033487 Equus caballus 78.68 2.00e-64 235.00
IUUC-Eeu-034696 Erinaceus europaeus 76.51 2.00e-77 280.00
IUUC-Fca-035975 Felis catus 74.03 4.00e-32 127.00
IUUC-Fal-037439 Ficedula albicollis 77.55 3.00e-69 252.00
IUUC-Fox-037781 Fusarium oxysporum 64.25 8.00e-70 255.00
IUUC-Fso-038377 Fusarium solani 60.44 6.00e-66 242.00
IUUC-Gmo-038945 Gadus morhua 71.58 5.00e-76 275.00
IUUC-Ggr-039834 Gaeumannomyces graminis 56.86 8.00e-68 248.00
IUUC-Gga-040495 Gallus gallus 73.91 1.00e-81 294.00
IUUC-Gac-042306 Gasterosteus aculeatus 71.82 3.00e-79 286.00
IUUC-Gma-043539 Glycine max 36.07 3.00e-31 128.00
IUUC-Ggo-045597 Gorilla gorilla 61.45 2.00e-60 224.00
IUUC-Hsa-046907 Homo sapiens 75.90 4.00e-77 279.00
IUUC-Hvu-047298 Hordeum vulgare 31.68 3.00e-27 115.00
IUUC-Itr-048997 Ictidomys tridecemlineatus 71.74 2.00e-80 290.00
IUUC-Kpa-049319 Komagataella pastoris 68.33 4.00e-75 273.00
IUUC-Lch-049771 Latimeria chalumnae 70.65 1.00e-80 291.00
IUUC-Lpe-050904 Leersia perrieri 33.16 1.00e-27 116.00
IUUC-Loc-052063 Lepisosteus oculatus 66.98 3.00e-82 296.00
IUUC-Lma-053280 Leptosphaeria maculans 48.44 1.00e-46 179.00
IUUC-Laf-054214 Loxodonta africana 72.28 3.00e-81 293.00
IUUC-Mcc-054778 Macaca mulatta 75.90 5.00e-77 279.00
IUUC-Meu-056598 Macropus eugenii 74.63 7.00e-27 112.00
IUUC-Mor-056989 Magnaporthe oryzae 58.70 1.00e-65 241.00
IUUC-Mpo-057591 Magnaporthe poae 60.64 2.00e-68 250.00
IUUC-Mtr-057924 Medicago truncatula 36.45 1.00e-33 136.00
IUUC-Mla-058931 Melampsora laricipopulina 59.46 9.00e-73 265.00
IUUC-Mga-060001 Meleagris gallopavo 80.15 1.00e-65 240.00
IUUC-Mvi-060513 Microbotryum violaceum 63.89 1.00e-67 248.00
IUUC-Mmr-061725 Microcebus murinus 72.28 4.00e-81 293.00
IUUC-Mdo-062715 Monodelphis domestica 71.74 9.00e-81 292.00
IUUC-Mmu-063203 Mus musculus 77.11 5.00e-78 282.00
IUUC-Mac-065392 Musa acuminata 39.20 1.00e-35 141.00
IUUC-Mpu-066174 Mustela putorius furo 72.28 4.00e-81 292.00
IUUC-Mlu-067883 Myotis lucifugus 77.94 1.00e-64 236.00
IUUC-Nfi-068317 Neosartorya fischeri 63.64 2.00e-73 267.00
IUUC-Ncr-068822 Neurospora crassa 59.14 5.00e-67 246.00
IUUC-Nle-069231 Nomascus leucogenys 75.90 4.00e-77 279.00
IUUC-Opr-070417 Ochotona princeps 79.70 3.00e-64 235.00
IUUC-Ont-072168 Oreochromis niloticus 71.27 1.00e-78 284.00
IUUC-Oan-072690 Ornithorhynchus anatinus 74.03 4.00e-32 127.00
IUUC-Ocu-074537 Oryctolagus cuniculus 72.28 1.00e-80 291.00
IUUC-Oba-075333 Oryza barthii 33.33 1.00e-28 119.00
IUUC-Obr-076255 Oryza brachyantha 40.23 1.00e-28 118.00
IUUC-Ogl-077792 Oryza glaberrima 33.16 5.00e-29 119.00
IUUC-Ogu-078354 Oryza glumaepatula 33.16 2.00e-28 119.00
IUUC-Oin-079934 Oryza indica 32.65 6.00e-28 117.00
IUUC-Olo-080643 Oryza longistaminata 39.08 5.00e-27 114.00
IUUC-Ome-081632 Oryza meridionalis 34.21 8.00e-28 117.00
IUUC-Oni-083004 Oryza nivara 32.65 6.00e-28 117.00
IUUC-Opu-083899 Oryza punctata 33.16 6.00e-28 117.00
IUUC-Oru-084386 Oryza rufipogon 33.16 2.00e-28 118.00
IUUC-Osa-085665 Oryza sativa 39.08 3.00e-27 114.00
IUUC-Ola-086577 Oryzias latipes 72.13 5.00e-79 285.00
IUUC-Olu-087867 Ostreococcus lucimarinus 42.41 2.00e-37 147.00
IUUC-Oga-088652 Otolemur garnettii 77.11 4.00e-77 279.00
IUUC-Oar-089965 Ovis aries 71.74 8.00e-81 291.00
IUUC-Ptr-090833 Pan troglodytes 75.90 4.00e-77 279.00
IUUC-Psi-093542 Pelodiscus sinensis 65.24 4.00e-70 256.00
IUUC-Pma-094423 Petromyzon marinus 75.52 1.00e-63 233.00
IUUC-Pno-095091 Phaeosphaeria nodorum 66.85 3.00e-73 267.00
IUUC-Ppa-096013 Physcomitrella patens 35.48 2.00e-29 122.00
IUUC-Pfo-097146 Poecilia formosa 64.81 4.00e-80 289.00
IUUC-Pab-098744 Pongo abelii 75.90 4.00e-77 279.00
IUUC-Pop-099917 Populus trichocarpa 39.75 8.00e-31 126.00
IUUC-Pca-100111 Procavia capensis 72.28 4.00e-81 292.00
IUUC-Ppe-101984 Prunus persica 38.14 4.00e-29 120.00
IUUC-Pva-103078 Pteropus vampyrus 71.74 2.00e-79 286.00
IUUC-Pgr-103438 Puccinia graminis 60.43 1.00e-67 248.00
IUUC-Ptt-103875 Puccinia triticina 56.86 4.00e-66 243.00
IUUC-Pte-104180 Pyrenophora teres 65.76 2.00e-71 261.00
IUUC-Pyt-104552 Pyrenophora triticirepentis 65.76 1.00e-71 261.00
IUUC-Rno-105506 Rattus norvegicus 64.41 5.00e-82 295.00
IUUC-Sce-106375 Saccharomyces cerevisiae 65.95 1.00e-71 261.00
IUUC-Sha-107585 Sarcophilus harrisii 77.21 4.00e-64 235.00
IUUC-Sja-107871 Schizosaccharomyces japonicus 64.86 2.00e-72 263.00
IUUC-Spo-108282 Schizosaccharomyces pombe 65.78 6.00e-73 265.00
IUUC-Smo-109561 Selaginella moellendorffii 38.12 3.00e-33 134.00
IUUC-Sit-110577 Setaria italica 37.44 2.00e-28 119.00
IUUC-Sly-111719 Solanum lycopersicum 35.64 9.00e-32 129.00
IUUC-Stu-112752 Solanum tuberosum 36.14 3.00e-33 134.00
IUUC-Sar-113701 Sorex araneus 70.97 6.00e-81 291.00
IUUC-Sbi-114308 Sorghum bicolor 34.34 4.00e-30 124.00
IUUC-Sre-115125 Sporisorium reilianum 65.75 6.00e-73 266.00
IUUC-Tgu-117039 Taeniopygia guttata 79.41 2.00e-65 239.00
IUUC-Tru-117939 Takifugu rubripes 72.38 5.00e-80 289.00
IUUC-Tsy-118852 Tarsius syrichta 67.67 3.00e-51 192.00
IUUC-Tni-120356 Tetraodon nigroviridis 70.65 2.00e-78 283.00
IUUC-Tca-121422 Theobroma cacao 37.28 3.00e-31 128.00
IUUC-Tre-122035 Trichoderma reesei 62.90 1.00e-69 254.00
IUUC-Tvi-122649 Trichoderma virens 62.90 4.00e-69 253.00
IUUC-Tae-124146 Triticum aestivum 31.82 1.00e-27 115.00
IUUC-Tme-127015 Tuber melanosporum 64.64 8.00e-69 252.00
IUUC-Tbe-128024 Tupaia belangeri 66.92 9.00e-51 190.00
IUUC-Ttr-128474 Tursiops truncatus 71.74 7.00e-81 291.00
IUUC-Uma-129655 Ustilago maydis 65.75 2.00e-73 268.00
IUUC-Vda-129970 Verticillium dahliae 60.11 6.00e-67 246.00
IUUC-Vpa-130564 Vicugna pacos 79.70 3.00e-64 235.00
IUUC-Vvi-131597 Vitis vinifera 39.33 5.00e-29 120.00
IUUC-Xtr-132201 Xenopus tropicalis 63.04 7.00e-82 295.00
IUUC-Xma-133679 Xiphophorus maculatus 71.82 6.00e-80 288.00
IUUC-Yli-134489 Yarrowia lipolytica 63.98 2.00e-76 277.00
IUUC-Zma-135058 Zea mays 33.84 2.00e-30 125.00
Created Date 25-Jun-2017

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