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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-047009
UUCD1 version UUC-HoS-00831
Ensembl Protein ID ENSP00000265981.2
UniProt Accession Q8WVD5; A8K149; Q9NZB4; RN141_HUMAN
Genbank Protein ID AAF30180.1; BAF82453.1; EAW68566.1; AAH18104.1; AAP35308.1
Protein Name RING finger protein 141; Zinc finger protein 230
Genbank Nucleotide ID AF214680; AK289764; CH471064; BC018104; BT006662
Gene Name RNF141; ZNF230
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000110315.6 ENST00000265981.6 ENSP00000265981.2
ENSG00000110315.6 ENST00000530156.1 ENSP00000437167.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircRNADbCircNet
miRTarBasemicroRNATRANSFACTargetScan
RepTarSomamiRmiRcodeRAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
MenthaInWeb_IM
Protein 3D Structure
PDBMMDB
Disease-associated Information
GWASdbOMIM
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlus
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
E3 activity/RING/RING RING 24105792
Classification
Family E-value Score Start End
E3 activity/RING/RING 6.10e-07 31.5 155 192
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC++   d  l+lpC H f+++C+ kw      s ++ +CP+Cr
   Q: 155  CCICMDGRAD--LILPCAHSFCQKCIDKW------SDRHRNCPICR 192
           ******9999..55***************......**********8 PP
   
Organism Homo sapiens
Functional Description
(View)

Functional Description


     May be involved in spermatogenesis.
 May be involved in spermatogenesis.
Protein Sequence
(Fasta)
MGQQISDQTQ LVINKLPEKV AKHVTLVRES GSLTYEEFLG RVAELNDVTA KVASGQEKHL 60
LFEVQPGSDS SAFWKVVVRV VCTKINKSSG IVEASRIMNL YQFIQLYKDI TSQAAGVLAQ 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-047009|E3,RING|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ACAGAGGTGC GACCGGGTCC CGGCCTGAGT CGCGGCCACC CGCAGGTCTG AGCTGTGGGC 60
TGAGGCAGCG CAGCCGCTGC CGCAGGGTGC GCGATGCCTT GAACCTGGGG TGAGCTCCGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-047009|E3,RING|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0449--Lipoprotein
KW-0472--Membrane
KW-0479--Metal-binding
KW-0519--Myristate
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2
SMART

SM00184--RING
Gene Ontology

GO:0016020--C:membrane
GO:0003677--F:DNA binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0051865--P:protein autoubiquitination
GO:0006355--P:regulation of transcription, DNA-templated
KEGG hsa:50862
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000996 Aegilops tauschii 30.85 5.00e-09 54.30
IUUC-Aml-001667 Ailuropoda melanoleuca 96.52 6.00e-134 469.00
IUUC-Atr-002441 Amborella trichopoda 41.54 4.00e-10 58.20
IUUC-Apl-003740 Anas platyrhynchos 85.46 1.00e-118 418.00
IUUC-Aca-004541 Anolis carolinensis 83.04 9.00e-117 412.00
IUUC-Ame-011210 Astyanax mexicanus 75.65 6.00e-105 373.00
IUUC-Bta-012755 Bos taurus 97.83 7.00e-135 472.00
IUUC-Bdi-014630 Brachypodium distachyon 38.81 1.00e-09 57.00
IUUC-Bra-016994 Brassica rapa 39.68 2.00e-08 52.80
IUUC-Cel-018183 Caenorhabditis elegans 28.00 2.00e-16 78.60
IUUC-Cja-019484 Callithrix jacchus 98.26 4.00e-126 443.00
IUUC-Cfa-020513 Canis familiaris 97.39 2.00e-135 474.00
IUUC-Cpo-021640 Cavia porcellus 96.09 5.00e-133 466.00
IUUC-Csa-023929 Chlorocebus sabaeus 100.00 2.00e-137 481.00
IUUC-Cho-024712 Choloepus hoffmanni 95.45 3.00e-72 263.00
IUUC-Dre-027893 Danio rerio 76.09 1.00e-104 372.00
IUUC-Dno-029490 Dasypus novemcinctus 95.65 3.00e-132 463.00
IUUC-Dor-030614 Dipodomys ordii 58.19 2.00e-43 168.00
IUUC-Ete-032783 Echinops telfairi 78.60 2.00e-95 341.00
IUUC-Eca-034396 Equus caballus 96.96 3.00e-134 470.00
IUUC-Eeu-035127 Erinaceus europaeus 91.74 5.00e-126 443.00
IUUC-Fca-036513 Felis catus 91.74 9.00e-127 445.00
IUUC-Fal-037395 Ficedula albicollis 85.65 9.00e-121 425.00
IUUC-Fso-038096 Fusarium solani 35.38 2.00e-07 49.30
IUUC-Gmo-039655 Gadus morhua 73.04 5.00e-102 363.00
IUUC-Gga-040726 Gallus gallus 84.35 6.00e-108 383.00
IUUC-Gac-042012 Gasterosteus aculeatus 74.78 3.00e-105 374.00
IUUC-Gma-043685 Glycine max 40.30 3.00e-10 58.90
IUUC-Ggo-044554 Gorilla gorilla 100.00 2.00e-137 481.00
IUUC-Itr-047975 Ictidomys tridecemlineatus 97.39 4.00e-133 466.00
IUUC-Lch-050250 Latimeria chalumnae 79.17 7.00e-113 399.00
IUUC-Lpe-050730 Leersia perrieri 38.81 1.00e-09 56.60
IUUC-Loc-052562 Lepisosteus oculatus 81.74 2.00e-110 391.00
IUUC-Laf-053522 Loxodonta africana 93.91 1.00e-129 455.00
IUUC-Mcc-054924 Macaca mulatta 100.00 2.00e-137 481.00
IUUC-Meu-056708 Macropus eugenii 71.00 8.00e-92 329.00
IUUC-Mtr-057890 Medicago truncatula 37.33 3.00e-09 55.50
IUUC-Mga-059628 Meleagris gallopavo 83.04 8.00e-109 385.00
IUUC-Mmr-061571 Microcebus murinus 98.70 2.00e-136 478.00
IUUC-Mdo-062852 Monodelphis domestica 91.34 1.00e-125 441.00
IUUC-Mmu-063260 Mus musculus 99.13 2.00e-136 477.00
IUUC-Mac-064729 Musa acuminata 37.68 1.00e-10 60.50
IUUC-Mpu-066728 Mustela putorius furo 96.52 9.00e-134 468.00
IUUC-Mlu-068171 Myotis lucifugus 97.39 4.00e-134 469.00
IUUC-Nle-069598 Nomascus leucogenys 100.00 2.00e-137 481.00
IUUC-Opr-070440 Ochotona princeps 73.04 6.00e-90 323.00
IUUC-Ont-072220 Oreochromis niloticus 76.09 1.00e-105 375.00
IUUC-Oan-073618 Ornithorhynchus anatinus 92.17 1.00e-125 442.00
IUUC-Ocu-074638 Oryctolagus cuniculus 97.39 8.00e-135 472.00
IUUC-Oba-075867 Oryza barthii 24.34 3.00e-09 55.80
IUUC-Obr-076083 Oryza brachyantha 37.88 6.00e-09 54.70
IUUC-Ogl-077580 Oryza glaberrima 39.39 2.00e-09 56.20
IUUC-Ogu-078162 Oryza glumaepatula 38.81 2.00e-09 55.80
IUUC-Oin-079986 Oryza indica 38.81 1.00e-09 56.60
IUUC-Olo-080306 Oryza longistaminata 39.39 2.00e-09 56.20
IUUC-Ome-081355 Oryza meridionalis 38.24 1.00e-09 56.60
IUUC-Oni-082456 Oryza nivara 39.39 1.00e-09 56.60
IUUC-Opu-084086 Oryza punctata 25.00 7.00e-10 57.80
IUUC-Oru-084301 Oryza rufipogon 39.39 1.00e-09 56.60
IUUC-Osa-085728 Oryza sativa 38.24 4.00e-09 55.10
IUUC-Ola-086610 Oryzias latipes 72.84 1.00e-98 352.00
IUUC-Olu-087723 Ostreococcus lucimarinus 43.59 2.00e-06 47.80
IUUC-Oga-089014 Otolemur garnettii 97.41 3.00e-132 464.00
IUUC-Oar-089731 Ovis aries 98.70 2.00e-136 478.00
IUUC-Ptr-091461 Pan troglodytes 98.70 3.00e-135 474.00
IUUC-Pan-092822 Papio anubis 100.00 2.00e-137 481.00
IUUC-Psi-093268 Pelodiscus sinensis 83.91 3.00e-110 390.00
IUUC-Pma-094294 Petromyzon marinus 48.92 4.00e-61 227.00
IUUC-Ppa-095463 Physcomitrella patens 35.71 5.00e-09 54.70
IUUC-Pfo-097386 Poecilia formosa 75.65 2.00e-104 371.00
IUUC-Pab-098668 Pongo abelii 93.91 9.00e-126 442.00
IUUC-Pop-099490 Populus trichocarpa 40.30 4.00e-10 58.50
IUUC-Pca-100715 Procavia capensis 90.97 5.00e-74 269.00
IUUC-Ppe-101436 Prunus persica 40.00 6.00e-09 54.30
IUUC-Pva-102192 Pteropus vampyrus 97.39 7.00e-127 446.00
IUUC-Rno-105281 Rattus norvegicus 98.26 2.00e-135 474.00
IUUC-Sha-107102 Sarcophilus harrisii 90.48 5.00e-120 423.00
IUUC-Smo-109000 Selaginella moellendorffii 36.62 7.00e-10 57.40
IUUC-Sit-110346 Setaria italica 38.81 2.00e-09 56.20
IUUC-Sly-111299 Solanum lycopersicum 39.39 3.00e-09 55.50
IUUC-Stu-112196 Solanum tuberosum 39.39 7.00e-09 54.30
IUUC-Sar-113049 Sorex araneus 95.65 4.00e-132 463.00
IUUC-Sbi-114022 Sorghum bicolor 38.81 9.00e-10 57.00
IUUC-Ssc-115234 Sus scrofa 97.40 4.00e-134 469.00
IUUC-Tgu-116861 Taeniopygia guttata 85.65 9.00e-121 425.00
IUUC-Tru-118629 Takifugu rubripes 74.78 4.00e-105 373.00
IUUC-Tsy-119495 Tarsius syrichta 99.57 3.00e-137 480.00
IUUC-Tni-120480 Tetraodon nigroviridis 73.48 4.00e-103 367.00
IUUC-Tca-121345 Theobroma cacao 40.79 1.00e-10 59.70
IUUC-Tae-123570 Triticum aestivum 30.00 1.00e-09 57.00
IUUC-Tur-126155 Triticum urartu 30.28 1.00e-09 57.80
IUUC-Tbe-128140 Tupaia belangeri 65.93 4.00e-61 226.00
IUUC-Ttr-128354 Tursiops truncatus 98.68 6.00e-135 472.00
IUUC-Vpa-130742 Vicugna pacos 96.96 2.00e-134 471.00
IUUC-Vvi-130899 Vitis vinifera 37.66 2.00e-09 56.20
IUUC-Xtr-132961 Xenopus tropicalis 78.15 7.00e-111 393.00
IUUC-Xma-133082 Xiphophorus maculatus 77.35 5.00e-81 293.00
Created Date 25-Jun-2017

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