iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052221

Ensembl Protein ID

ENSLOCP00000008763.1

UniProt Accession

W5MK54; W5MK54_LEPOC

Genbank Protein ID

ENSLOCP00000008763

Protein Name

Protein kinase C

Genbank Nucleotide ID

AHAT01015257

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000007237.1	ENSLOCT00000008773.1	ENSLOCP00000008763.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UFD/PB1	5.50e-22	77.9	19	101

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UFD/PB1

   S: 1    tvrvkvsykgeirsfaldlekpgkfedLlkavrtltelkn.sevalkYeDedGDlvtlksDedldkavslla.skksllrlliqk 83
           +vrvk++ykg+i  + +++e+++++e L+++vr++++++n + +++k+ De+GD +t++s+ +l++a++l++ +k+s l +++++
   Q: 19   QVRVKAYYKGDI--MITHFEPSISYEGLYSEVRDMCSFDNdQLFTMKWIDEEGDPCTVSSQLELEEALRLYElNKDSELIIHVFP 101
           69**********..88*******************************************************************86 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MMPTLRDSTM SHPGENPNQV RVKAYYKGDI MITHFEPSIS YEGLYSEVRD MCSFDNDQLF 60
TMKWIDEEGD PCTVSSQLEL EEALRLYELN KDSELIIHVF PSVPEKPGMP CAGEDKSIYR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATGCCTA CGTTGCGGGA CAGTACTATG TCCCACCCAG GAGAGAATCC TAACCAAGTG 60
CGGGTGAAAG CCTATTATAA GGGGTGAGTG GAAATCAGTA TATTGGCTGG ATCGGTCCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000961--AGC-kinase_C
IPR034661--aPKC_iota
IPR020454--DAG/PE-bd
IPR011009--Kinase-like_dom
IPR000270--PB1_dom
IPR002219--PE/DAG-bd
IPR012233--PKC
IPR017892--Pkinase_C
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS51285--AGC_KINASE_CTER
PS51745--PB1
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF00564--PB1
PF00069--Pkinase
PF00433--Pkinase_C

PRINTS

PR00008--DAGPEDOMAIN

SMART

SM00109--C1
SM00666--PB1
SM00133--S_TK_X
SM00220--S_TKc

Gene Ontology

GO:0005622--C:intracellular
GO:0031226--C:intrinsic component of plasma membrane
GO:0005915--C:zonula adherens
GO:0005524--F:ATP binding
GO:0046872--F:metal ion binding
GO:0004697--F:protein kinase C activity
GO:0034334--P:adherens junction maintenance
GO:0045217--P:cell-cell junction maintenance
GO:0007502--P:digestive tract mesoderm development
GO:0048546--P:digestive tract morphogenesis
GO:0021744--P:dorsal motor nucleus of vagus nerve development
GO:0035050--P:embryonic heart tube development
GO:0000132--P:establishment of mitotic spindle orientation
GO:0016332--P:establishment or maintenance of polarity of embryonic epithelium
GO:0035556--P:intracellular signal transduction
GO:0045199--P:maintenance of epithelial cell apical/basal polarity
GO:0008078--P:mesodermal cell migration
GO:0001738--P:morphogenesis of a polarized epithelium
GO:0001841--P:neural tube formation
GO:0007405--P:neuroblast proliferation
GO:0007097--P:nuclear migration
GO:0042476--P:odontogenesis
GO:0035845--P:photoreceptor cell outer segment organization
GO:0035778--P:pronephric nephron tubule epithelial cell differentiation
GO:0060042--P:retina morphogenesis in camera-type eye
GO:0021591--P:ventricular system development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001764	Ailuropoda melanoleuca	90.65	0.00e+00	959.00
IUUC-Apl-003711	Anas platyrhynchos	91.13	0.00e+00	1039.00
IUUC-Aca-005142	Anolis carolinensis	90.56	0.00e+00	1052.00
IUUC-Ame-010977	Astyanax mexicanus	89.63	0.00e+00	1031.00
IUUC-Bta-013414	Bos taurus	89.26	0.00e+00	1077.00
IUUC-Cel-018340	Caenorhabditis elegans	58.57	0.00e+00	715.00
IUUC-Cja-019802	Callithrix jacchus	90.76	0.00e+00	1038.00
IUUC-Cfa-021236	Canis familiaris	88.42	0.00e+00	1058.00
IUUC-Cpo-022127	Cavia porcellus	88.89	0.00e+00	1009.00
IUUC-Csa-023332	Chlorocebus sabaeus	91.29	0.00e+00	895.00
IUUC-Cho-025054	Choloepus hoffmanni	92.68	1.00e-66	247.00
IUUC-Cin-025740	Ciona intestinalis	60.49	0.00e+00	703.00
IUUC-Csv-026145	Ciona savignyi	77.75	8.00e-175	606.00
IUUC-Dre-028444	Danio rerio	91.85	0.00e+00	1060.00
IUUC-Dno-029228	Dasypus novemcinctus	97.10	0.00e+00	637.00
IUUC-Dme-031630	Drosophila melanogaster	68.13	0.00e+00	805.00
IUUC-Ete-032633	Echinops telfairi	66.94	2.00e-173	602.00
IUUC-Eca-033572	Equus caballus	91.10	0.00e+00	1044.00
IUUC-Eeu-035110	Erinaceus europaeus	89.08	0.00e+00	1062.00
IUUC-Fca-035559	Felis catus	89.26	0.00e+00	1079.00
IUUC-Fal-036953	Ficedula albicollis	91.64	0.00e+00	1047.00
IUUC-Gmo-039334	Gadus morhua	90.83	0.00e+00	1081.00
IUUC-Gga-040223	Gallus gallus	88.98	0.00e+00	1071.00
IUUC-Gac-042113	Gasterosteus aculeatus	91.68	0.00e+00	1097.00
IUUC-Ggo-044520	Gorilla gorilla	84.46	0.00e+00	964.00
IUUC-Hsa-046991	Homo sapiens	89.43	0.00e+00	1080.00
IUUC-Lch-050263	Latimeria chalumnae	89.98	0.00e+00	1073.00
IUUC-Laf-053591	Loxodonta africana	89.60	0.00e+00	1080.00
IUUC-Mcc-055118	Macaca mulatta	88.40	0.00e+00	1059.00
IUUC-Mga-059886	Meleagris gallopavo	91.13	0.00e+00	1038.00
IUUC-Mmr-060926	Microcebus murinus	89.09	0.00e+00	1076.00
IUUC-Mdo-062698	Monodelphis domestica	87.09	0.00e+00	1048.00
IUUC-Mmu-063689	Mus musculus	88.94	0.00e+00	1068.00
IUUC-Mpu-066630	Mustela putorius furo	90.47	0.00e+00	1066.00
IUUC-Mlu-067416	Myotis lucifugus	86.10	0.00e+00	1020.00
IUUC-Nle-069811	Nomascus leucogenys	89.09	0.00e+00	1076.00
IUUC-Opr-070466	Ochotona princeps	80.94	0.00e+00	701.00
IUUC-Ont-072278	Oreochromis niloticus	87.89	0.00e+00	997.00
IUUC-Oan-073651	Ornithorhynchus anatinus	96.13	0.00e+00	732.00
IUUC-Ocu-074383	Oryctolagus cuniculus	89.26	0.00e+00	1075.00
IUUC-Ola-087283	Oryzias latipes	83.30	0.00e+00	834.00
IUUC-Oga-088337	Otolemur garnettii	82.36	0.00e+00	971.00
IUUC-Oar-089954	Ovis aries	90.94	0.00e+00	1048.00
IUUC-Ptr-091673	Pan troglodytes	89.43	0.00e+00	1080.00
IUUC-Pan-092494	Papio anubis	89.26	0.00e+00	1076.00
IUUC-Psi-094044	Pelodiscus sinensis	87.81	0.00e+00	1063.00
IUUC-Pfo-096661	Poecilia formosa	88.55	0.00e+00	1031.00
IUUC-Pab-097659	Pongo abelii	88.76	0.00e+00	1070.00
IUUC-Pca-101107	Procavia capensis	91.48	0.00e+00	761.00
IUUC-Rno-105790	Rattus norvegicus	89.09	0.00e+00	1072.00
IUUC-Sha-106895	Sarcophilus harrisii	90.64	0.00e+00	1024.00
IUUC-Sar-113513	Sorex araneus	86.60	3.00e-158	551.00
IUUC-Sre-115203	Sporisorium reilianum	32.84	3.00e-29	122.00
IUUC-Ssc-115835	Sus scrofa	90.42	0.00e+00	959.00
IUUC-Tgu-116874	Taeniopygia guttata	89.18	0.00e+00	1072.00
IUUC-Tru-117823	Takifugu rubripes	89.64	0.00e+00	1036.00
IUUC-Tsy-119154	Tarsius syrichta	91.28	0.00e+00	1045.00
IUUC-Tni-119968	Tetraodon nigroviridis	89.46	0.00e+00	1040.00
IUUC-Tbe-127238	Tupaia belangeri	71.52	0.00e+00	672.00
IUUC-Ttr-129208	Tursiops truncatus	88.94	0.00e+00	1075.00
IUUC-Vpa-130363	Vicugna pacos	79.36	0.00e+00	919.00
IUUC-Xtr-132652	Xenopus tropicalis	85.57	0.00e+00	1034.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence