iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052087

Ensembl Protein ID

ENSLOCP00000010435.1

UniProt Accession

W5MPX6; W5MPX6_LEPOC

Genbank Protein ID

ENSLOCP00000010435

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01010059

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000008578.1	ENSLOCT00000010449.1	ENSLOCP00000010435.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.00e-14	52.4	406	755

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs....g 86
           G++ ++N+CYm+++L +L++++++ + ll k  +  ++      +++ll+++ + +     +++++v+ ++++k  k++ e  +    +
   Q: 406  GIQGHCNSCYMDATLFSLFSCSSVLDSLLFKSAQPSDA----LIQATLLREIVNPL-----RTEGYVEASSVMKLRKQLMEGGHcasfT 485
           99****************************33333322....23445544444444.....4444444444444444433332233359 PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde....aeekkkkknkslisdlFqgqlksqikclecdnvs.sreepfl 170
           ++++D +Efl+ +++++         k k+ e++ ++    ++    +++      ++l+++ F+  l     +++c   +  r+ + +
   Q: 486  TDEKDPEEFLNLVMHHILALD--PLLKLKTGEQKVQDGYCYQIfidqNNSLALPTVQQLLEHSFHSALLRLAEVPSCLILQmPRFGKKF 572
           9**************997643..333444444444444555552222445555555566666666666677779*****9999**9999 PP
   S: 171  dlslpvpgkeetkkeslqdcLesftkeeelegenk.yycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple 258
           +l  ++  + e    +++d+L++  +e+ l+ge + ++c +c ++ +    +++k+++ + + +           +++++ + + +p+ 
   Q: 573  KLFDKIIPSLEL---DITDLLSDSPQECVLCGELAtMECAECFRDAT-FSNTGFKQFCYTCSKQVHSL-----PRRQKHVPSPLLLPEG 652
           999999999888...******************9889******9885.56679***999888777766.....3456788999999988 PP
   S: 259  LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn..ekgkWllfdD.................................s 312
               +++  p       ++ eL+av++ +      HYv++vk   ++++W+ fd                                   
   Q: 653  YPTGKYLRPPR------EQLELFAVLCIET----SHYVSFVKYgpSSQDWIFFDSmadrygdedgynipavqlcpevgqylemplgelA 731
           88999998866......457*******999....9********6555559999998888888888888666666666666666665555 PP
   S: 313  kVtevkeeevleetgstaYvlfYk 336
            V + ++e v +   ++aY+++Y+
   Q: 732  AVCPRDMEGVAKRLFCDAYMYLYQ 755
           555555555555555999999998 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

SKGKYLYFIC VEKTHNSFIP GSICYIEERR YLEKFENDSN PEHLPVMAMG SMVSYHVKVM 60
ALRHLSETEA GLLQAIVEDA QRLRYFLHRD ELDSALALKI DAPVSVEIRS EWCQGILRYI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCCAAAGGGA AGTACCTGTA CTTCATCTGT GTGGAGAAGA CCCATAATTC ATTCATCCCG 60
GGCAGCATAT GTTACATTGA GGAAAGACGG TATCTGGAAA AGTTTGAGAA TGATTCAAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000938--CAP-Gly_domain
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50245--CAP_GLY_2
PS00972--USP_1
PS50235--USP_3

Pfam

PF01302--CAP_GLY
PF00443--UCH

SMART

SM01052--CAP_GLY

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-005309	Anolis carolinensis	60.40	9.00e-162	563.00
IUUC-Ame-011228	Astyanax mexicanus	45.41	5.00e-169	588.00
IUUC-Cel-018528	Caenorhabditis elegans	38.42	4.00e-60	226.00
IUUC-Dre-027403	Danio rerio	52.76	0.00e+00	693.00
IUUC-Fal-036822	Ficedula albicollis	58.97	2.00e-163	569.00
IUUC-Gmo-038716	Gadus morhua	61.85	5.00e-170	590.00
IUUC-Gga-041013	Gallus gallus	55.56	2.00e-168	585.00
IUUC-Gac-041692	Gasterosteus aculeatus	63.68	7.00e-175	606.00
IUUC-Mga-060127	Meleagris gallopavo	64.02	9.00e-145	507.00
IUUC-Psi-093121	Pelodiscus sinensis	47.85	0.00e+00	680.00
IUUC-Pfo-097363	Poecilia formosa	53.02	0.00e+00	706.00
IUUC-Tru-117966	Takifugu rubripes	57.80	2.00e-167	582.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence