DNA & RNA Element - UTRdb Gene Name Type ASPicDB UTRaspic Refseq ID Genome TLE2 3'UTR 0d345f430a BA109643 NM_001144761 chr19:2948636-2979901:- TLE2 3'UTR 793893190f BA109644 NM_001144761 chr19:2948636-2996785:- TLE2 3'UTR e089ba03fb BA109645 NM_001144761 chr19:2948636-2996785:- TLE2 3'UTR 204d0ae5bd BA109646 NM_001144761 chr19:2948636-2996785:- TLE2 3'UTR ef56b49cdb BA109647 NM_001144761 chr19:2948636-2996785:- TLE2 3'UTR 24ed330d64 BA109648 NM_001144761 chr19:2948636-2979901:- TLE2 3'UTR 9fbc93f081 BA109649 NM_001144761 chr19:2948636-2979901:- TLE2 3'UTR 3e0581d21c BA109650 NM_001144761 chr19:2948636-2996785:- TLE2 3'UTR 7b5c1bd841 BA109651 NM_001144761 chr19:2948636-2996785:- TLE2 3'UTR 9194e32808 BA109652 NM_001144761 chr19:2948636-2996785:- TLE2 3'UTR 5f255ebdb8 BA109653 NM_001144761 chr19:2948636-2996785:- TLE2 3'UTR 1f3e250e7a BA109654 NM_001144761 chr19:2948636-2979901:- TLE2 3'UTR 65c3f222f8 BA109655 NM_001144761 chr19:2948636-2979901:- TLE2 3'UTR c00ade3d79 BA109656 NM_001144761 chr19:2948636-2979901:- TLE2 3'UTR 727d835f91 BA109657 NM_001144761 chr19:2948636-2979901:- TLE2 3'UTR 36b8d730cd BA109658 NM_001144761 chr19:2948636-2979901:- TLE2 3'UTR 30b42f5868 BA109659 NM_001144761 chr19:2948636-2979901:- TLE2 3'UTR 63812c89ef BA109660 NM_001144761 chr19:2948636-2979901:- TLE2 3'UTR 4ce3c12f6b BA109661 NM_001144761 chr19:2948636-2979901:- TLE2 3'UTR 67f0a4f347 BA109662 NM_001144761 chr19:2948636-2979901:- TLE2 3'UTR 6d07e05afc BA109663 NM_001144761 chr19:2948636-2979901:- TLE2 3'UTR 20b9279024 BA109664 NM_001144761 chr19:2948636-2979901:- TLE2 3'UTR 7e81e836af NM_001144761 chr19:2948636-2980611:- TLE2 3'UTR ff2deb98af NM_001144761 chr19:2948636-2980611:- TLE2 3'UTR 57025532f0 NM_001144761 chr19:2948636-2979901:- TLE2 3'UTR dc9d854e28 NM_001144761 chr19:2948636-2979901:- TLE2 3'UTR 2db31fb961 NM_001144761 chr19:2948636-2996785:- TLE2 3'UTR 3423082dd3 NM_001144761 chr19:2948636-2996785:- TLE2 3'UTR eabf37a66c NM_001144761 chr19:2948636-2980611:- TLE2 3'UTR 4dbabfee6d NM_001144761 chr19:2948636-2980611:- TLE2 3'UTR ba00ad412d NM_001144761 chr19:2948636-2959942:- TLE2 3'UTR 90f0f1ad56 NM_001144761 chr19:2948636-2959942:- TLE2 3'UTR 74091fa8b0 NM_001144761 chr19:2948636-2996785:- TLE2 3'UTR c9157dd626 NM_001144761 chr19:2948636-2996785:- TLE2 3'UTR 32c682d46a NM_001144761 chr19:2948636-2979901:- TLE2 3'UTR 3204eda68b NM_001144761 chr19:2948636-2979901:- TLE2 3'UTR b49d0630b7 NM_001144761 chr19:2948636-2959942:- TLE2 3'UTR 7f07ac13a3 NM_001144761 chr19:2948636-2959942:- TLE2 3'UTR adbdf90d13 NM_001144761 chr19:2948636-2962156:- TLE2 3'UTR e759991edf NM_001144761 chr19:2948636-2976372:- TLE2 3'UTR b8c012b93b NM_001144761 chr19:2948636-2976372:- TLE2 3'UTR ad98b69de7 NM_001144761 chr19:2948636-2971586:- TLE2 3'UTR ad733076de NM_001144761 chr19:2948636-2971586:- TLE2 3'UTR 1c3ea8833f NM_001144761 chr19:2948636-2979901:- TLE2 3'UTR 42b3fdfe51 NM_001144761 chr19:2948636-2979901:- TLE2 3'UTR 5f1d06da6b NM_001144761 chr19:2948636-2976372:- TLE2 3'UTR ec435b063c NM_001144761 chr19:2948636-2976372:- TLE2 3'UTR 5ca725e2d5 NM_001144761 chr19:2948636-2971586:- TLE2 3'UTR ce7bed2115 NM_001144761 chr19:2948636-2971586:- TLE2 3'UTR b2c2f0d1e7 NM_001144761 chr19:2948636-2970477:- TLE2 3'UTR 9fedb1a7d1 NM_001144761 chr19:2948636-2970477:- TLE2 3'UTR 1373510dfa NM_001144761 chr19:2948636-2970477:- TLE2 3'UTR 37d30b5804 NM_001144761 chr19:2948636-2970477:- TLE2 3'UTR 6c1d3fbbfe NM_001144761 chr19:2948636-2970772:- TLE2 3'UTR 917f512662 NM_001144761 chr19:2948636-2959942:- TLE2 3'UTR 0c145b88d6 NM_001144761 chr19:2948636-2970772:- TLE2 3'UTR 6049b398a2 NM_001144761 chr19:2970281-2996785:- TLE2 3'UTR 68a02e30fb NM_001144761 chr19:2970281-2979901:- TLE2 3'UTR 92cc69c2e4 NM_001144761 chr19:2948636-2959942:- TLE2 3'UTR 84ff0d63a8 NM_001144761 chr19:2970281-2976372:- TLE2 5'UTR 0d345f430a CA172918 NM_001144761 chr19:2948847-2980018:- TLE2 5'UTR 793893190f CA172919 NM_001144761 chr19:2948847-2998846:- TLE2 5'UTR e089ba03fb CA172920 NM_001144761 chr19:2948847-2998846:- TLE2 5'UTR 204d0ae5bd CA172921 NM_001144761 chr19:2948847-2998846:- TLE2 5'UTR ef56b49cdb CA172922 NM_001144761 chr19:2948847-2998846:- TLE2 5'UTR 24ed330d64 CA172923 NM_001144761 chr19:2948847-2980620:- TLE2 5'UTR 9fbc93f081 CA172924 NM_001144761 chr19:2948847-2980620:- TLE2 5'UTR 3e0581d21c CA172925 NM_001144761 chr19:2948923-2998846:- TLE2 5'UTR 7b5c1bd841 CA172926 NM_001144761 chr19:2948923-2998846:- TLE2 5'UTR 9194e32808 CA172927 NM_001144761 chr19:2948923-2998846:- TLE2 5'UTR 5f255ebdb8 CA172928 NM_001144761 chr19:2948923-2998846:- TLE2 5'UTR 1f3e250e7a CA172929 NM_001144761 chr19:2948923-2980620:- TLE2 5'UTR 65c3f222f8 CA172930 NM_001144761 chr19:2948923-2980620:- TLE2 5'UTR c00ade3d79 CA172931 NM_001144761 chr19:2948847-2980175:- TLE2 5'UTR 727d835f91 CA172932 NM_001144761 chr19:2948847-2980175:- TLE2 5'UTR 36b8d730cd CA172933 NM_001144761 chr19:2948847-2980175:- TLE2 5'UTR 30b42f5868 CA172934 NM_001144761 chr19:2948923-2980175:- TLE2 5'UTR 63812c89ef CA172935 NM_001144761 chr19:2948923-2980175:- TLE2 5'UTR 4ce3c12f6b CA172936 NM_001144761 chr19:2970620-2980175:- TLE2 5'UTR 67f0a4f347 CA172937 NM_001144761 chr19:2970620-2980175:- TLE2 5'UTR 6d07e05afc CA172938 NM_001144761 chr19:2948923-2980175:- TLE2 5'UTR 20b9279024 CA172939 NM_001144761 chr19:2948923-2980175:-

DNA & RNA Element - circBase circRNA ID Chrom Start End Strand hsa_circ_0048440 chr19 3008866 3008943 - hsa_circ_0048438 chr19 2997635 3009700 - hsa_circ_0048439 chr19 3005434 3008943 - hsa_circ_0048441 chr19 3008866 3015758 -

DNA & RNA Element - circRNADb circRNA ID Chrom Start End Strand Samples hsa_circ_04740 chr19 3000644 3002501 - normal brain tissue

DNA & RNA Element - CircNet Circ ID GITPosition Express Symbol Entrez Category Strand Refered Name hsa-circ-TLE2.10 NM_003260Tchr19:3008866-3015758 none TLE2 7089 protein-coding - hsa_circ_0048441 hsa-circ-TLE2.14 NM_001300846Tchr19:3019280-3019771 expressed TLE2 7089 protein-coding - not_available hsa-circ-TLE2.16 NM_001144762Tchr19:3008866-3008943 none TLE2 7089 protein-coding - hsa_circ_0048440 hsa-circ-TLE2.17 NM_001300846Tchr19:3005434-3008943 none TLE2 7089 protein-coding - hsa_circ_0048439 hsa-circ-TLE2.19 NM_003260Tchr19:2997635-3009700 expressed TLE2 7089 protein-coding - hsa_circ_0048438 hsa-circ-TLE2.22 NM_001300846Tchr19:3000644-3002501 expressed TLE2 7089 protein-coding - hsa_circ_0109354 hsa-circ-TLE2.6 NM_001144761Tchr19:2997635-3009700 expressed TLE2 7089 protein-coding - hsa_circ_0048438 hsa-circ-TLE2.8 NM_003260Tchr19:3019280-3019771 expressed TLE2 7089 protein-coding - not_available

DNA & RNA Element - microRNA Mirbase Acc miRNA Name Gene ID Gene Symbol miRNA Alignment Alignment Gene Alignment miRNA Start miRNA End Gene Start Gene End Genome Coordinates Conservation Align Score Seed Cat Energy mirSVR Score MIMAT0004509 hsa-miR-93* 7089 TLE2 gcccuucacgaucgAGUCGUCa ||||||| gacucccaggggaaUCAGCAGc 2 9 33 54 [hg19:19:2997792-2997813:-] 0.4453 140 7 -16.67 -0.1618 MIMAT0004509 hsa-miR-93* 7089 TLE2 gcccuucacgaucgAGUCGUCa ||||||| gacucccaggggaaUCAGCAGc 2 9 109 130 [hg19:19:2997792-2997813:-] 0.4453 140 7 -16.67 -0.1627 MIMAT0004516 hsa-miR-105* 7089 TLE2 aucgUGUACG-AGUU--UGUAGGCa | |||: || | ||||||| aauaAAAUGUAUCUAUCACAUCCGc 2 19 185 209 [hg19:19:2997637-2997661:-] 0.5511 148 7 -14.31 -0.3771 MIMAT0004516 hsa-miR-105* 7089 TLE2 aucgUGUACG-AGUU--UGUAGGCa | |||: || | ||||||| aauaAAAUGUAUCUAUCACAUCCGc 2 19 261 285 [hg19:19:2997637-2997661:-] 0.5511 148 7 -14.31 -0.3637 MIMAT0004564 hsa-miR-214* 7089 TLE2 cgUGUCGUUCACAU----CUGUCCGu |:| ||| | | ||||||| aaAUAACAAAUACAUCGUGACAGGCu 2 21 10 35 [hg19:19:2997887-2997912:-] 0.8173 143 7 -15.84 -0.3604 MIMAT0004569 hsa-miR-222* 7089 TLE2 uccUAGAUGUGACC-GAUGACUc :| |: : ||| ||||||| cguGUAUGAGGUGGUCUACUGAg 2 20 55 77 [hg19:19:2997845-2997867:-] 0.8173 150 7 -18.35 -0.6974 MIMAT0004596 hsa-miR-138-2* 7089 TLE2 uugggaccACAGCACUUUAUcg | || |||||| ------caUCUCCAGAAAUAac 3 15 1 16 [hg19:19:2997906-2997921:-] 0.8173 126 0 -3.67 -0.1680 MIMAT0000721 hsa-miR-369-3p 7089 TLE2 uuUCUAGUUGGUACAUA-AUAa | || || |||||| ||| ggAAAUAAA--AUGUAUCUAUc 2 20 182 201 [hg19:19:2997645-2997664:-] 0.5511 120 0 -4.81 -0.2590 MIMAT0000721 hsa-miR-369-3p 7089 TLE2 uuUCUAGUUGGUACAUA-AUAa | || || |||||| ||| ggAAAUAAA--AUGUAUCUAUc 2 20 258 277 [hg19:19:2997645-2997664:-] 0.5511 120 0 -4.81 -0.2487 MIMAT0000760 hsa-miR-331-3p 7089 TLE2 aagauccUAUCCGGGUCCCCg | | |||||||| gaaguccAGACUCCCAGGGGa 2 15 25 45 [hg19:19:2997801-2997821:-] 0.4453 146 7 -20.34 -0.2047 MIMAT0000760 hsa-miR-331-3p 7089 TLE2 aagauccUAUCCGGGUCCCCg | | |||||||| gaaguccAGACUCCCAGGGGa 2 15 101 121 [hg19:19:2997801-2997821:-] 0.4453 146 7 -20.34 -0.1827 MIMAT0002176 hsa-miR-485-3p 7089 TLE2 ucUCUCCUCUCGGCACAUACUg ||| |: |||||||||| caAGAAGGCCACCGUGUAUGAg 2 21 43 64 [hg19:19:2997858-2997879:-] 0.8173 164 7 -22.65 -0.1014 MIMAT0002847 hsa-miR-518c* 7089 TLE2 gucuuucacgaagGGAGGUCUcu :||||||| -----------caUCUCCAGAaa 3 11 1 12 [hg19:19:2997910-2997921:-] 0.8173 126 0 -12.60 -0.1608 MIMAT0002859 hsa-miR-516b 7089 TLE2 uuucacgaagaaUGGAGGUCUa |:||||||| -----------cAUCUCCAGAa 2 11 1 11 [hg19:19:2997911-2997921:-] 0.8173 146 7 -13.79 -1.0560 MIMAT0003243 hsa-miR-578 7089 TLE2 ugUUAGGAUCUCGUGUUCUUc |: |: :|:| ||||||| acAGGCUCGGGGGACAAGAAg 2 20 29 49 [hg19:19:2997873-2997893:-] 0.8173 155 7 -22.70 -0.1953 MIMAT0003289 hsa-miR-620 7089 TLE2 uaaagauauagaUAGAGGUa ||||||| -----------cAUCUCCAg 2 9 1 9 [hg19:19:2997913-2997921:-] 0.8173 140 7 -9.37 -0.5738 MIMAT0010364 hsa-miR-761 7089 TLE2 acacaGUCAAAGUGGGACGACg || ||| |||||||| cuucaCACCUUC-CCCUGCUGc 2 18 130 150 [hg19:19:2997696-2997716:-] 0.4577 155 7 -23.56 -0.1229 MIMAT0010364 hsa-miR-761 7089 TLE2 acacaGUCAAAGUGGGACGACg || ||| |||||||| cuucaCACCUUC-CCCUGCUGc 2 18 206 226 [hg19:19:2997696-2997716:-] 0.4577 155 7 -23.56 -0.1174 MIMAT0004915 hsa-miR-220c 7089 TLE2 ucaGAAGUGUUG-UCGGGAC-ACa ||||||| | ||||| || cggCUUCACACCUUCCCCUGCUGc 2 20 127 150 [hg19:19:2997696-2997719:-] 0.4577 126 0 -21.16 -0.1895 MIMAT0004915 hsa-miR-220c 7089 TLE2 ucaGAAGUGUUG-UCGGGAC-ACa ||||||| | ||||| || cggCUUCACACCUUCCCCUGCUGc 2 20 203 226 [hg19:19:2997696-2997719:-] 0.4577 126 0 -21.16 -0.1815 MIMAT0004957 hsa-miR-760 7089 TLE2 agGGGU-GUCUGGGUC-UCGGc |||| :|| :||| |||| cuCCCAGGGGAAUCAGCAGCCa 2 19 35 56 [hg19:19:2997790-2997811:-] 0.4095 121 0 -22.87 -0.1955 MIMAT0004957 hsa-miR-760 7089 TLE2 agGGGU-GUCUGGGUC-UCGGc |||| :|| :||| |||| cuCCCAGGGGAAUCAGCAGCCa 2 19 111 132 [hg19:19:2997790-2997811:-] 0.4095 121 0 -22.87 -0.1644 MIMAT0004979 hsa-miR-936 7089 TLE2 gacgcuaaggagggAGAUGACa ||||||| cguguaugagguggUCUACUGa 2 9 55 76 [hg19:19:2997846-2997867:-] 0.8173 140 7 -11.93 -0.7047 MIMAT0004983 hsa-miR-940 7089 TLE2 ccccucgccccCGGGACGGAa ||||||||| gccgccucccaGCCCUGCCUa 2 11 74 94 [hg19:19:2997752-2997772:-] 0.3970 150 7 -18.95 -0.1225 MIMAT0004983 hsa-miR-940 7089 TLE2 ccccucgccccCGGGACGGAa ||||||||| gccgccucccaGCCCUGCCUa 2 11 150 170 [hg19:19:2997752-2997772:-] 0.3970 150 7 -18.95 -0.1168 MIMAT0005887 hsa-miR-1299 7089 TLE2 agggagugugucuuaAGGUCUu |||||| -----------caucUCCAGAa 2 8 1 11 [hg19:19:2997911-2997921:-] 0.8173 120 6 -10.07 -0.1514 MIMAT0005900 hsa-miR-1248 7089 TLE2 aaaucgUGUCACGA---AUAUGUUCUUCCa |||| ||| : ||||||||| aucgugACAG-GCUCGGGGGACAAGAAGGc 2 22 23 51 [hg19:19:2997871-2997899:-] 0.8173 154 7 -22.72 -0.2308 MIMAT0005902 hsa-miR-1250 7089 TLE2 uuUCCGG--UGUAGG-UCGU-GGCa ||| | |||||| |||| ||| ccAGGACAGACAUCCUAGCAGCCGc 2 20 54 78 [hg19:19:2997768-2997792:-] 0.3737 129 0 -23.57 -0.1308 MIMAT0005902 hsa-miR-1250 7089 TLE2 uuUCCGG--UGUAGG-UCGU-GGCa ||| | |||||| |||| ||| ccAGGACAGACAUCCUAGCAGCCGc 2 20 130 154 [hg19:19:2997768-2997792:-] 0.3737 129 0 -23.57 -0.1244 MIMAT0005924 hsa-miR-1270 7089 TLE2 ugugucgagaagguaUAGAGGUc ||||||| --------------cAUCUCCAg 2 9 1 9 [hg19:19:2997913-2997921:-] 0.8173 140 7 -13.47 -0.5738 MIMAT0007883 hsa-miR-1909 7089 TLE2 gccacucGUG-GGCCGGGGACGc ||| || ||||||| acggcuuCACACCUUCCCCUGCu 2 16 126 148 [hg19:19:2997698-2997720:-] 0.4577 150 7 -26.35 -0.1254 MIMAT0007883 hsa-miR-1909 7089 TLE2 gccacucGUG-GGCCGGGGACGc ||| || ||||||| acggcuuCACACCUUCCCCUGCu 2 16 202 224 [hg19:19:2997698-2997720:-] 0.4577 150 7 -26.35 -0.1199 MIMAT0011778 hsa-miR-2278 7089 TLE2 gguccGUUGUGUGUGACGAGAg || | ||: ||||||| ccguaCAUCCCAU-CUGCUCUc 2 18 99 119 [hg19:19:2997727-2997747:-] 0.4203 151 7 -20.64 -0.1835 MIMAT0011778 hsa-miR-2278 7089 TLE2 gguccGUUGUGUGUGACGAGAg || | ||: ||||||| ccguaCAUCCCAU-CUGCUCUc 2 18 175 195 [hg19:19:2997727-2997747:-] 0.4203 151 7 -20.64 -0.1757 MIMAT0014999 hsa-miR-378b 7089 TLE2 aaGACG-GAGGUUCAGGUCa |||: | | |||||||| ucCUGUACCCGAAGUCCAGa 2 18 91 110 [hg19:19:2997812-2997831:-] 0.3437 156 7 -21.52 -0.1421 MIMAT0015046 hsa-miR-3171 7089 TLE2 cuaUAUAUGUCUAAGGUA-UGUAGa ||| | | ||:|| ||||| gaaAUAAAAUGUAUCUAUCACAUCc 2 22 183 207 [hg19:19:2997639-2997663:-] 0.5511 125 0 -9.51 -0.3019 MIMAT0015046 hsa-miR-3171 7089 TLE2 cuaUAUAUGUC--UAAGG--UAUGUAGa || | ||| || | ||||||| --cAUCUCCAGAAAUAACAAAUACAUCg 2 22 1 26 [hg19:19:2997896-2997921:-] 0.8173 147 7 -9.81 -0.3118 MIMAT0015046 hsa-miR-3171 7089 TLE2 cuaUAUAUGUCUAAGGUA-UGUAGa ||| | | ||:|| ||||| gaaAUAAAAUGUAUCUAUCACAUCc 2 22 259 283 [hg19:19:2997639-2997663:-] 0.5511 125 0 -9.51 -0.2903 MIMAT0015056 hsa-miR-3179 7089 TLE2 ugcaaaUUUAAAGUGGGGAAGa | || | ||||||| -----gACAUGACCCCCCUUCc 2 17 1 17 [hg19:19:2997829-2997845:-] 0.3437 148 7 -13.51 -0.1418 MIMAT0015056 hsa-miR-3179 7089 TLE2 ugcaaaUUUAAAGUGGGGAAGa | || | ||||||| acugagACAUGACCCCCCUUCc 2 17 72 93 [hg19:19:2997829-2997850:-] 0.5016 148 7 -13.51 -0.1120 MIMAT0015076 hsa-miR-3192 7089 TLE2 aaGGUGACGAUGUUGGAGGGUCu ||: | | ||: ||||||| acCCGAAG-UCCAGACUCCCAGg 2 22 21 42 [hg19:19:2997804-2997825:-] 0.4453 151 7 -22.29 -0.1582 MIMAT0015076 hsa-miR-3192 7089 TLE2 aaGGUGACGAUGUUGGAGGGUCu ||: | | ||: ||||||| acCCGAAG-UCCAGACUCCCAGg 2 22 97 118 [hg19:19:2997804-2997825:-] 0.4453 151 7 -22.29 -0.1468 MIMAT0015089 hsa-miR-3202 7089 TLE2 uaaUUUCGAGAAGAGGGAAGGu |:| | | ||||||| cugAGACAUGACCCCCCUUCCu 2 20 73 94 [hg19:19:2997828-2997849:-] 0.5016 143 7 -13.04 -0.1150 MIMAT0016847 hsa-miR-378c 7089 TLE2 gguGAGAA-GAC-UGAGGUUCAGGUCa | ||| ||| || | |||||||| cccCCCUUCCUGUACCCGAAGUCCAGa 2 23 84 110 [hg19:19:2997812-2997838:-] 0.3437 168 7 -26.31 -0.1435 MIMAT0016853 hsa-miR-4300 7089 TLE2 cuuCAUCAGGUC-GAGGGu | ||||||| ||||| cccGAAGUCCAGACUCCCa 2 16 22 40 [hg19:19:2997806-2997824:-] 0.4453 131 0 -24.74 -0.1433 MIMAT0016853 hsa-miR-4300 7089 TLE2 cuuCAUCAGGUC-GAGGGu | ||||||| ||||| cccGAAGUCCAGACUCCCa 2 16 98 116 [hg19:19:2997806-2997824:-] 0.4453 131 0 -24.74 -0.1694 MIMAT0016861 hsa-miR-4308 7089 TLE2 uuCUUC---UUUGA-GGUCCCu |||| |:||| |||||| ccGAAGUCCAGACUCCCAGGGg 2 17 23 44 [hg19:19:2997802-2997823:-] 0.4453 123 6 -21.19 -0.1449 MIMAT0016861 hsa-miR-4308 7089 TLE2 uuCUUC---UUUGA-GGUCCCu |||| |:||| |||||| ccGAAGUCCAGACUCCCAGGGg 2 17 99 120 [hg19:19:2997802-2997823:-] 0.4453 123 6 -21.19 -0.1034 MIMAT0016884 hsa-miR-4254 7089 TLE2 cucuaccaccucaUCGAGGUCcg | |||||| ------------cAUCUCCAGaa 3 11 1 11 [hg19:19:2997911-2997921:-] 0.8173 122 0 -9.69 -0.1446 MIMAT0016901 hsa-miR-4271 7089 TLE2 gggguggaaaaGAAGGGGg ||||||| cggcuucacacCUUCCCCu 2 9 127 145 [hg19:19:2997701-2997719:-] 0.4577 140 7 -21.86 -0.1388 MIMAT0016901 hsa-miR-4271 7089 TLE2 gggguggaaaaGAAGGGGg ||||||| cggcuucacacCUUCCCCu 2 9 203 221 [hg19:19:2997701-2997719:-] 0.4577 140 7 -21.86 -0.1327 MIMAT0016919 hsa-miR-4292 7089 TLE2 ggUUCCGGCC---GGGUCCCc ||| || | ||||||| cgAAGUCCAGACUCCCAGGGg 2 17 24 44 [hg19:19:2997802-2997822:-] 0.4453 147 7 -23.97 -0.1175 MIMAT0000271 hsa-miR-214 7089 TLE2 ugacggacaGACACGGACGACa || ||||||| gcuucacacCUUCCCCUGCUGc 2 14 129 150 [hg19:19:2997696-2997717:-] 0.4577 141 7 -16.54 -0.1241 MIMAT0000271 hsa-miR-214 7089 TLE2 ugacggacaGACACGGACGACa || ||||||| gcuucacacCUUCCCCUGCUGc 2 14 205 226 [hg19:19:2997696-2997717:-] 0.4577 141 7 -16.54 -0.1186 MIMAT0000435 hsa-miR-143 7089 TLE2 cucgaugucacgaaGUAGAGu |||||| --------------CAUCUCc 2 8 1 7 [hg19:19:2997915-2997921:-] 0.8173 120 6 -7.37 -0.1120 MIMAT0000732 hsa-miR-378 7089 TLE2 ggAAGAC-UGAGGUUCAGGUCa | ||| || | |||||||| cuUCCUGUACCCGAAGUCCAGa 2 20 89 110 [hg19:19:2997812-2997833:-] 0.3437 162 7 -22.40 -0.1435 MIMAT0001339 hsa-miR-422a 7089 TLE2 cgGAA-GAC-UGGGAUUCAGGUCa ||| ||| |||| |||||||| ccCUUCCUGUACCCGAAGUCCAGa 2 21 87 110 [hg19:19:2997812-2997835:-] 0.3437 174 7 -30.91 -0.1421 MIMAT0003283 hsa-miR-615-3p 7089 TLE2 uucucccucuggGUCCGAGCCu ||||||||| aauacaucgugaCAGGCUCGGg 2 11 18 39 [hg19:19:2997883-2997904:-] 0.8173 150 7 -22.21 -0.8671 MIMAT0003329 hsa-miR-411 7089 TLE2 gcAUGCGAUAUGCCAGAUGAu ||:| | ::|||||||| ugUAUG--AGGUGGUCUACUg 2 20 57 75 [hg19:19:2997847-2997865:-] 0.8173 152 7 -24.28 -0.4953

DNA & RNA Element - TRANSFAC Accession AS Description Species Entrez Pubmed Binding Info G009436 TLE2 Homo sapiens 7089

DNA & RNA Element - TargetScan Gene Name UTR Region Start UTR Region End AIR Total Normalized 3P-seq-tags & Pseudocounts Strand hg19_chromosome Genome Start Genome End TLE2 1 202 100 29.289 - chr19 2997643 2997845 TLE2 203 210 17.105 29.289 - chr19 2997635 2997643

DNA & RNA Element - RepTar Gene Name miRNA Begin End Profile TLE2 hsa-miR-762 beg:71 end:90 pic:3' CGAGCCGG-GGCCGGGGTCGGGG 5'& ||| || .||||||||. &5' -----GCCGCC--TCCCAGCCCT 3' TLE2 hsa-miR-331-3p beg:34 end:45 pic:3' AAGATCCTATCCGGGTCCCCG 5'& |||||||| &5' ------------CCCAGGGG- 3' TLE2 hsa-miR-1909 beg:132 end:148 pic:3' GCCACTCGTGGGCCGGGGACGC 5'& ||||. ||||||| &5' -------CACCTT-CCCCTGC- 3' TLE2 hsa-miR-3179 beg:5 end:17 pic:3' TGCAAATTTAAAGTGGGGAAGA 5'& | ||||||| &5' ------------CCCCCCTTC- 3' TLE2 hsa-miR-3202 beg:8 end:18 pic:3' TAATTTCGAGAAGAGGGAAGGT 5'& ||||||| &5' --------------CCCTTCC- 3' TLE2 hsa-miR-30bstar beg:67 end:86 pic:3' CTTCATTTGTAGGTGGAGGGTC 5'& |.|| ||.|||||||| &5' ------AGCAGCCGCCTCCCAG 3' TLE2 hsa-miR-761 beg:132 end:151 pic:3' ACACAGTCAAAGTGGGACGACG 5'& || ||| ||||||||| &5' -----CACCTTC-CCCTGCTGC 3' TLE2 hsa-miR-4271 beg:127 end:146 pic:3' GGGGTGGAAAAGAAGGGGG 5'& |..||| |||||||. &5' CTTCACAC---CTTCCCCT 3' TLE2 ebv-miR-BART5star beg:37 end:56 pic:3' TCCACTT-GTCGCCGGGTG 5'& ||| ||| |||| ||| &5' AGGGGAATCAGCAGCC--- 3' TLE2 hsa-miR-1306 beg:111 end:129 pic:3' GTGGTGGTCTCGGTTGCA 5'& .|. | .||||||| &5' -GCTCTCT-GGCCAACG- 3' TLE2 hcmv-miR-US25-2-3p beg:164 end:185 pic:3' GGCGCCCTCGAGAGGTTCACCTA 5'& || ||.| ||| .||||| &5' --GCAGGGGACCTC--GGTGGA- 3' TLE2 hiv1-miR-H1 beg:64 end:84 pic:3' CGGGTC--CGTGCGGAGGGACC 5'& ||.|| || |||||||| &5' -CCTAGCAGC-CGCCTCCC--- 3' TLE2 hsa-miR-1207-5p beg:72 end:93 pic:3' GG-GGAGGGTCGGAGGGACGGT 5'& || ||||||||| |||||| &5' CCGCCTCCCAGC---CCTGCC- 3' TLE2 hsa-miR-1224-5p beg:72 end:92 pic:3' GGTGGAGGGCTCAGGAGTG 5'& ||.|||||| || || .| &5' CCGCCTCCC-AG-CCCTGC 3' TLE2 hsa-miR-1225-5p beg:5 end:26 pic:3' GGGGGGTGACCCGGCATGGGTG 5'& |||||| |.||||||. &5' CCCCCCTTC---CTGTACCCG- 3' TLE2 hsa-miR-1228star beg:71 end:95 pic:3' GTGTGTGGACG---GGGGCGGGTG 5'& .| |.||| | |||.|||.| &5' -GC-CGCCTCCCAGCCCTGCCTA- 3' TLE2 hsa-miR-1237 beg:151 end:174 pic:3' GACCCCCTGC--CTCGTCTTCCT 5'& |||||| || |.||||..| &5' -TGGGGGCCGATGGGCAGGGG-- 3' TLE2 hsa-miR-1246 beg:13 end:33 pic:3' GGACGAGGTTTTTAGGTAA 5'& ||||. || .||.|||| &5' CCTGTACCCGAAGTCCA-- 3' TLE2 hsa-miR-1258 beg:51 end:73 pic:3' AAGGTGCTGGAT-TAGGATTGA 5'& ||| ||| ||||||.| &5' --CCAGGACAGACATCCTAGC- 3' TLE2 hsa-miR-1265 beg:48 end:70 pic:3' TTGTTGTGAACTGG-TGTAGGAC 5'& |.||.| | ||| ||||||| &5' AGCAGC-CAGGACAGACATCCT- 3' TLE2 hsa-miR-1274a beg:153 end:174 pic:3' ACCGCGG--ACTTGTCCCTG 5'& || ||| ||..|||||. &5' -GGGGCCGATGGGCAGGGG- 3' TLE2 hsa-miR-1321 beg:0 end:20 pic:3' TAGTGTAA---GTGGAGGGAC 5'& |||| | |||.|||| &5' ---ACATGACCCCCCTTCCTG 3' TLE2 hsa-miR-185star beg:69 end:90 pic:3' CTGGTCTCCTTTCGGTCGGGGA 5'& ||| |||||||. &5' ---CAGCCGCCTCCCAGCCCT- 3' TLE2 hsa-miR-188-3p beg:139 end:159 pic:3' ACGTTTGGG---ACGTACACCCTC 5'& ||| ||||||||||.| &5' ------CCCTGCTGCATGTGGGGG 3' TLE2 hsa-miR-1908 beg:69 end:93 pic:3' CTGGTTAGCGGCA----GGGGCGGC 5'& || |||| |||.||| &5' ---CAGCCGCCTCCCAGCCCTGCC- 3' TLE2 hsa-miR-1915star beg:150 end:173 pic:3' CCGGGCCCGTCGTTCCGTTCCA 5'& |. |||| | .||||.|| &5' -GTGGGGGCCGATGGGCAGGG- 3' TLE2 hsa-miR-196a beg:78 end:95 pic:3' GGGTTGTTGTACTTTGATGGAT 5'& ||||.| ||.|||| &5' CCCAGCC--------CTGCCTA 3' TLE2 hsa-miR-196b beg:78 end:95 pic:3' GGGTTGTTGTCCTTTGATGGAT 5'& ||||.| ||.|||| &5' CCCAGCC--------CTGCCTA 3' TLE2 hsa-miR-196b beg:44 end:71 pic:3' GGGTTGTT-GTCCT--TTGATGGAT 5'& .||.||. ||||| .|| |||| &5' -TCAGCAGCCAGGACAGACATCCTA 3' TLE2 hsa-miR-202 beg:77 end:94 pic:3' AAGGGTACGGGATATGGAGA 5'& ||||| ||||| .||| &5' -TCCCA-GCCCT--GCCT-- 3' TLE2 hsa-miR-2113 beg:41 end:64 pic:3' CACT--GTC-TCGGTTCGTGTTTA 5'& || ||| |||||.| |||.| &5' --GAATCAGCAGCCAGG-ACAGA- 3' TLE2 hsa-miR-2278 beg:96 end:120 pic:3' GGTCCGTTGTGTGTGACGAGAG 5'& ||. || | ||. |||||||| &5' CCGTACATCCCAT-CTGCTCTC 3' TLE2 hsa-miR-2861 beg:72 end:94 pic:3' GGCGGGTGG-CGGTCCGGGG 5'& ||||| || ||| |||. &5' CCGCCTCCCAGCCCTGCCT- 3' TLE2 hsa-miR-296-3p beg:67 end:90 pic:3' CCTC-TCGGAGGTGGGTTGGGAG 5'& || |||| || ||||.|||| &5' --AGCAGCCGCCTCCCAGCCCT- 3' TLE2 hsa-miR-29astar beg:30 end:51 pic:3' GACTTGTGGTTTTCTTTAGTCA 5'& .|| || |..|.|||||| &5' ---GACTCCCAGGGGAATCAG- 3' TLE2 hsa-miR-3137 beg:102 end:130 pic:3' TGGGGTA-ACGAGGGTCCGA-TGTCT 5'& |.||||| |||||.| ||| ||.| &5' ATCCCATCTGCTCTCTGGCCAACGG- 3' TLE2 hsa-miR-3141 beg:72 end:94 pic:3' AGGAGGAGG--TGGG-CGGGAG 5'& || ||||| .||| |||. &5' -CCGCCTCCCAGCCCTGCCT-- 3' TLE2 hsa-miR-3187 beg:111 end:127 pic:3' GGCGCGTCGGGGTACCGGTT 5'& ||.|. ||||||| &5' -------GCTCTCTGGCCAA 3' TLE2 hsa-miR-3189 beg:18 end:45 pic:3' GATGGGG--TA-GTCT--GGGTTCCC 5'& ||||| .| |||| ||||.||| &5' -TACCCGAAGTCCAGACTCCCAGGGG 3' TLE2 hsa-miR-3192 beg:63 end:86 pic:3' AAGGTGACGATGTTGGAGGGTCT 5'& ||| || .| .|||||||| &5' -TCCTA-GCAGCCGCCTCCCAG- 3' TLE2 hsa-miR-320e beg:75 end:92 pic:3' GGAAGAGTTGGGTCGAAA 5'& ||| | ||.||| || &5' CCTCC-CAGCCCTGC--- 3' TLE2 hsa-miR-339-5p beg:151 end:174 pic:3' GCACTCGAGGACCTCCTGTCCCT 5'& |||.| || ||.|||||. &5' -GTGGGGGCCGAT-GGGCAGGGG 3' TLE2 hsa-miR-34bstar beg:80 end:95 pic:3' GTTAGTCGATTACTGTGACGGAT 5'& |||| | ||||||| &5' ----CAGC------C-CTGCCTA 3' TLE2 hsa-miR-378 beg:10 end:34 pic:3' GGAA-GAC-TGAGG-TTCAGGTCA 5'& |||| ||| || || |||||||| &5' CCTTCCTGTAC-CCGAAGTCCAG- 3' TLE2 hsa-miR-378c beg:14 end:34 pic:3' GGTGAGAAGAC-TGAGG-TTCAGGTCA 5'& ||| || || |||||||| &5' --------CTGTAC-CCGAAGTCCAG- 3' TLE2 hsa-miR-422a beg:14 end:34 pic:3' CGGAAGAC-TGGGATTCAGGTCA 5'& ||| |||| |||||||| &5' -----CTGTACCCGAAGTCCAG- 3' TLE2 hsa-miR-4281 beg:72 end:89 pic:3' GGGGGGAGGGGCCCTGGG 5'& || |||||| .||| &5' -CCGCCTCCCA---GCCC 3' TLE2 hsa-miR-4281 beg:5 end:25 pic:3' GGGGGGAGGGGCCCTGGG 5'& |||||||.||.| |||| &5' CCCCCCTTCCTGT-ACCC 3' TLE2 hsa-miR-4292 beg:23 end:45 pic:3' GGTTCCGGCC---GGGTCCCC 5'& | ||| || | |||||||| &5' CGAAGTCCAGACTCCCAGGGG 3' TLE2 hsa-miR-4294 beg:19 end:40 pic:3' GGGA--CGACATCTGAGGG 5'& ||| |. |||||||| &5' CCCGAAGTCC-AGACTCCC 3' TLE2 hsa-miR-4308 beg:22 end:45 pic:3' TTCTTC---TTTGA-GGTCCCT 5'& |||| |.||| ||||||. &5' --GAAGTCCAGACTCCCAGGGG 3' TLE2 hsa-miR-4314 beg:25 end:44 pic:3' GACAGGGTAAAGGGTCTC 5'& |||| ||||||.| &5' --GTCCAGACTCCCAGGG 3' TLE2 hsa-miR-4317 beg:29 end:46 pic:3' TTTGAGGGACCGTTACA 5'& |.|||||| || .| &5' AGACTCCCAGGGGA--- 3' TLE2 hsa-miR-513a-5p beg:1 end:21 pic:3' TACTGT--GGAGGGACACTT 5'& ||||| |||.||||| &5' ATGACCCCCCTTCCTGT--- 3' TLE2 hsa-miR-548s beg:109 end:126 pic:3' TTTTATTGACGTCAAAACCGGTA 5'& |||| |||||| &5' -------CTGCTCTC-TGGCCA- 3' TLE2 hsa-miR-564 beg:140 end:156 pic:3' CGGACGACTGTGGCACGGA 5'& ||||||| || .||| &5' -CCTGCTG-CA-TGTG--- 3' TLE2 hsa-miR-575 beg:111 end:133 pic:3' CGAG-GACAGGTTGACCGAG 5'& |||| ||| ||||| ||||. &5' GCTCTCTGGCCAAC-GGCTT 3' TLE2 hsa-miR-584 beg:88 end:104 pic:3' GAGTCAGGGTCCGTTTGGTATT 5'& ||.||| |||.|| &5' ------CCTAGGA--ACCGTA- 3' TLE2 hsa-miR-586 beg:178 end:197 pic:3' CCTGGATTTTTATGTTACGTAT 5'& |..||||| ||||.|| &5' -----TGGAAATAAAATGTAT- 3' TLE2 hsa-miR-588 beg:108 end:127 pic:3' CAAGATTGGGTAACACCGGTT 5'& ||| .|.| ||||||| &5' --TCT-GCTCTC--TGGCCAA 3' TLE2 hsa-miR-612 beg:74 end:96 pic:3' TTCCTC-GAGTCTTCGGGACGGGTCG 5'& | ||| |||||||||.|| &5' -----GCCTCCC-AGCCCTGCCTAG- 3' TLE2 hsa-miR-615-5p beg:157 end:179 pic:3' CTAGGCT-CGTGGCCCCTGGGGG 5'& |||| | .| |||||||.| &5' ---CCGATGGGCAGGGGACCTC- 3' TLE2 hsa-miR-623 beg:74 end:97 pic:3' TGGGTTGTCGGGGACGT-TCCCTA 5'& .||. ||| |||||| ||| &5' GCCTCCCAG-CCCTGCCTAGG--- 3' TLE2 hsa-miR-647 beg:68 end:79 pic:3' CTTCCTTCACTCACGTCGGTG 5'& ||||||.| &5' -------------GCAGCCGC 3' TLE2 hsa-miR-663 beg:72 end:94 pic:3' CGCCAGGGCGCCG---CGGGGCGGA 5'& |||| ||||.|||| &5' ------CCGCCTCCCAGCCCTGCCT 3' TLE2 hsa-miR-663b beg:114 end:139 pic:3' GGAGTCCG--TGCCGGCCCGGTGG 5'& ||| ||| |||||. |||| &5' -CTCTGGCCAACGGCTTCA-CACC 3' TLE2 hsa-miR-675 beg:8 end:24 pic:3' GTGACACCCGGGAGAGGCGTGGT 5'& |||| |.|.||| &5' ---------CCCTTCCTGTACC- 3' TLE2 hsa-miR-744 beg:71 end:92 pic:3' ACGACAATCGGGATCGGGGCGT 5'& || | ||| |||||.|| &5' -GCCGCCT-CCC-AGCCCTGC- 3' TLE2 hsa-miR-767-3p beg:151 end:172 pic:3' TCTTTGGTACCCCA---TACTCGTCT 5'& .||||| |||.||||. &5' -------GTGGGGGCCGATGGGCAGG 3' TLE2 hsa-miR-940 beg:74 end:94 pic:3' CCCCTCGCCCC--CGGGACGGAA 5'& || ||||||||| &5' -----GCCTCCCAGCCCTGCCT- 3' TLE2 hsv1-miR-H17 beg:72 end:93 pic:3' GGCGGAGCG-CGGGGTCGCGGT 5'& ||||||| ||||. ||| &5' CCGCCTCCCAGCCCT---GCC- 3' TLE2 hsv1-miR-H5-3p beg:113 end:124 pic:3' GGCCTCCCAAACCTAGAGACTG 5'& ||||||.| &5' --------------TCTCTGGC 3' TLE2 hsv2-miR-H10 beg:5 end:25 pic:3' GGCGGGTGGGGGCGTGGG 5'& || ||| ..||.|.|||| &5' CC-CCCCTTCCTGTACCC 3' TLE2 hsv2-miR-H3 beg:63 end:86 pic:3' GAGGGTTGGCGTCTGAGGGTTT 5'& |||.|.| || | ||||||. &5' -TCCTAGCAGCCGCCTCCCAG- 3' TLE2 hsv2-miR-H3 beg:19 end:43 pic:3' GAGGGTTGGC-GTCTGAGGGTTT 5'& |||.| ||||||||||.. &5' --CCCGAAGTCCAGACTCCCAGG 3' TLE2 kshv-miR-K12-5 beg:47 end:71 pic:3' TGGCCGTTCAAGGTCC-----GTAGGAT 5'& ||| ||||| ||||||| &5' ----GCAG---CCAGGACAGACATCCTA 3'

DNA & RNA Element - miRNAMap Gene Name Mature miRNA Target Start Target End miRNA 3-5 Alignment Target 5-3 TLE2 hsa-miR-214 143 150 ----GACGGACAGACAC-------------------GGACGACA ||||: |||| ||||||| CCAUCUGCUC-UCUGGCCAACGGCUUCACACCUUCCCCUGCUGC TLE2 hsa-miR-331 38 45 AAGAUCCUAUCC----------------------GGGUCCCCG |||||||| CAUGACCCCCCUUCCUGUACCCGAAGUCCAGACUCCCAGGGGA TLE2 hsa-miR-647 50 57 C-------------------------UUCCUUCACUCACGUCGGUG ::|||| ||||||| UCCUGUACCCGAAGUCCAGACUCCCAGGGGAAUCA---GCAGCCAG TLE2 hsa-let-7a 96 136 -UUGAUAUGU----UGGAUGA------------UGGAGU- ||| :|||| |:||:|| :|:||| GAACCGUACAUCCCAUCUGCUCUCUGGCCAACGGCUUCAC TLE2 hsa-let-7b 72 95 -UUGGUGU---GUUGGAUGAUGGAGU |:||:| ||:|| ||:||| CAGCCGCCUCCCAGCC--CUGCCUA- TLE2 hsa-let-7c 96 136 -UUGGUAUGU----UGGAUGA------------UGGAGU- ||||:|||| |:||:|| :|:||| GAACCGUACAUCCCAUCUGCUCUCUGGCCAACGGCUUCAC TLE2 hsa-miR-10a 148 174 GUGUUUAAGCCUAGA----UGUCCCAU :|| :| ||: | :||||| UGCAUGUGGGGGCCGAUGGGCAGGGG- TLE2 hsa-miR-125a 162 186 GUGUCCAAUUUCCCA-GAGUC-CCU- |::|| |:||| |||:| ||| GAUGGGC--AGGGGACCUCGGUGGAA TLE2 hsa-miR-127 120 165 -UCGGU--UCGA---------------GU----CUGCCUAGGCU :|||| :||| | | || |||| UGGCCAACGGCUUCACACCUUCCCCUGCUGCAUGUGGGGGCCGAU TLE2 hsa-miR-133a 143 165 UGUCGACCAACUUCCCCUGGUU- | |||| || ||||:||:| CCUGCUGCAUGU-GGGGGCCGAU TLE2 hsa-miR-133b 145 165 AUCGACCAACUUCCCCUGGUU- |||| || ||||:||:| -UGCUGCAUGU-GGGGGCCGAU TLE2 hsa-miR-134 114 138 -GGGAGACCAGUUGGUC-AGUGU- |:|||||| |||| : ||||| GCUCUCUGGCCAACGGCUUCACAC TLE2 hsa-miR-135a 35 58 -AGUGUAUCCUUAUUUUUCGGUAU || || :||||| |: ||||| CUCCCAGGGGAAUCAGCAGCCAG- TLE2 hsa-miR-135b 38 58 GUGUAUCCUUACUUUUCGGUAU || :||||| |: ||||| -CCAGGGGAAUCAGCAGCCAG- TLE2 hsa-miR-150 143 173 GUGACCAUGU---UCCCA----ACCC-UCU- ||| |:|| :||| |||| ||: -CCUGCUGCAUGUGGGGGCCGAUGGGCAGGG TLE2 hsa-miR-181a* 156 185 -CCAUGUUAGUUG-CC-----AGCUACCA || |:|| ::| || |||:||| GGGGCCGAUGGGCAGGGGACCUCGGUGGA TLE2 hsa-miR-184 106 127 UGGGAAUAGUCAAGAGGCAGGU- ||| ||| | ||||:| ||| UCCC--AUCUGCUCUCUGGCCAA TLE2 hsa-miR-188 141 167 UGGGAGGUGGUACGUUCCC---UAC- |||| | ||||: ||| ||| CCCCUGCUGCAUGUGGGGGCCGAUGG TLE2 hsa-miR-18a* 154 172 UCUUCCUCGUGAAUCCCGUCA :||:|| | |||||| --UGGGGGC-CGAUGGGCAGG TLE2 hsa-miR-191* 40 77 -CCCCUGCUUUA--GGUUCG-----------CGUCG- ||||| |||:| ||||| AGGGGAAUCAGCAGCCAGGACAGACAUCCUAGCAGCC TLE2 hsa-miR-193b 145 164 UUUCGCCCUGAA----ACUCCCGGUCAA :|| ||:|||||: -------UGCUGCAUGUGGGGGCCGA-- TLE2 hsa-miR-198 106 126 -GGAUAGAGGGGAGACCUGG- || |||| |:|||||| || UCCCAUCUGCUCUCUGG-CCA TLE2 hsa-miR-206 131 164 -GGUGUGUGAAGGA----AUGUAA------GGU- :||||| ||||| |:||| ||: UUCACAC-CUUCCCCUGCUGCAUGUGGGGGCCGA TLE2 hsa-miR-221 170 200 -CUUUGG-GUCGUCUG----UUACAUCGA- |::||| |:|::|| |||||| || GGGGACCUCGGUGGAAAUAAAAUGUAUCUA TLE2 hsa-miR-296 155 179 UGUCCUAACU-CCC--CCCCGGGA- :||: || ||| |||| ||| -GGGGGCCGAUGGGCAGGGGACCUC TLE2 hsa-miR-324-3p 142 168 -GGUCGUCGUGGA-CCCCGUC-ACC- || || |||: | ||||| | ||| CCCUGCUGCAUGUGGGGGCCGAUGGG TLE2 hsa-miR-328 150 173 -UGCCUUCCCGUCUCUCCCGGUC- |:| ::|||| || |||| :| CAUGUGGGGGCCGAU-GGGCAGGG TLE2 hsa-miR-331 151 170 AAGAUCCUAUCCGGGUCCCCG- | |:|| |||| | |||| AUGUGGG---GGCCGAUGGGCA TLE2 hsa-miR-339 153 175 -ACUCGAGGACCUCCUGUCCCU- ||:| || ||:|||||: GUGGGGGCCGAU-GGGCAGGGGA TLE2 hsa-miR-345 27 54 -CGGGACCUGA---UCCUC--AGUCGU- |:|| |||| |||:| |||||| AGUCCA-GACUCCCAGGGGAAUCAGCAG TLE2 hsa-miR-346 154 185 -UCUCCG----UCCGUACGCCC----GUCUGU- :|:||| :|||| ||| |:| : UGGGGGCCGAUGGGCAG--GGGACCUCGGUGGA TLE2 hsa-miR-34a 48 79 -UUGUUGGUCGAUUCUGUGA------CGGU- |:||:|||| |||||: |||: CAGCAGCCAGGACAGACAUCCUAGCAGCCGC TLE2 hsa-miR-34b 44 82 GUUAGUCGAUUA--CUG-------------UGACGGAU ||||||| ||| :| |||| GAAUCAGCAGCCAGGACAGACAUCCUAGCAGCCGCCUC TLE2 hsa-miR-363* 191 210 UUUAACGUAGCACUAG-GUGGGC- ||:||| ||| ||:||| ---AUGUAUCU--AUCACAUCCGC TLE2 hsa-miR-370 53 80 -GGUCCAAG--GUGGGGUCGUC--CG- ||||| ||:||:||||| || GCCAGGACAGACAUCCUAGCAGCCGCC TLE2 hsa-miR-378 148 175 -UGUG---UCCUGGAC-CUCAGUCCUC- :||: :||:|| |:| ||||:| UGCAUGUGGGGGCCGAUGGG-CAGGGGA TLE2 hsa-miR-412 165 186 UGCCGAUCACCUGGU-CCACUUCA ||| :| ||||| ||||:| -GGGCAGG-GGACCUCGGUGGAA- TLE2 hsa-miR-422a 11 35 CCGGAA-GAC-UGGGAUUCAGGUC- |||| ||| |||| |||||||| -CCCUUCCUGUACCCGAAGUCCAGA TLE2 hsa-miR-422b 11 35 CCGGAA-GAC-UGAGG-UUCAGGUC- |||| ||| || || |||||||| -CCCUUCCUGUAC-CCGAAGUCCAGA TLE2 hsa-miR-432 19 45 GGUGGGUUACUGGA-UGA-GGUUCU- :||||:| | || ||| |||:|: GUACCCGAAGUCCAGACUCCCAGGGG TLE2 hsa-miR-449 52 94 -UGGUC----------GAUUGUUA---------UGUGACGGU :|||| |||:||: :| ||||| AGCCAGGACAGACAUCCUAGCAGCCGCCUCCCAGCCCUGCCU TLE2 hsa-miR-449b 52 95 -CGGUC----------GAUUGUUA---------UGUGACGGA ||||| |||:||: :| |||||| AGCCAGGACAGACAUCCUAGCAGCCGCCUCCCAGCCCUGCCUA TLE2 hsa-miR-453 32 57 GCUUGAGUGGUGCC------UGUUGGAG :|||| ||| || :||:|| -AGACUC-CCAGGGGAAUCAGCAGCCA- TLE2 hsa-miR-485-5p 63 83 CUUAAGUAG---UGCCGGUCGGAGA |||| :| ||| ||||| ----ACAUCCUAGCAGCC-GCCUCC TLE2 hsa-miR-486 41 64 GAGCCC-----CGUCGAGUCAUGUCCU ||| ||||| ||| |||| --GGGGAAUCAGCAGC-CAGGACAGA- TLE2 hsa-miR-493-3p 157 181 GACCG----UGUGUCAUCUGGAAGU- ||| : :||| :||||| |: -GGGCCGAUGGGCAGGGGACCU-CGG TLE2 hsa-miR-502 155 175 AUCGUGGGUCUAUCGUUCCUA :| :|| | :|||:||: GGGGGCCGAUG-GGCAGGGGA TLE2 hsa-miR-503 87 118 -GACG---UCUUGACA---AGGGC-GACGAU |||| :|||| || |||| ||||| CCUGCCUAGGAACCGUACAUCCCAUCUGCUC TLE2 hsa-miR-513 3 22 UAUUUACUGU--GGAGGGACACUU ||||| |||:||||| ---CAUGACCCCCCUUCCUGUA-- TLE2 hsa-miR-520a* 93 124 -UCUUU--CAUGAAGGG--------AGACCUC ||:|| |||| |||| ||||| UAGGAACCGUACAUCCCAUCUGCUCUCUGGC- TLE2 hsa-miR-524 33 57 -UGAGGUUUCCCU---UCG-CGGAAG ||||| |:|||| ||| ||| GACUCCCAGGGGAAUCAGCAGCCA-- TLE2 hsa-miR-525 93 124 -UCUUU--CACGUAGGG--------AGACCUC ||:|| || |||||| ||||| UAGGAACCGUACAUCCCAUCUGCUCUCUGGC- TLE2 hsa-miR-557 164 189 -UCUGUUCCG-GGUGGGCACGUUUG- :|:||:|| || :| ||| |||: UGGGCAGGGGACC-UCGGUGGAAAUA TLE2 hsa-miR-558 41 58 UAAAACCAU--GUCGUCGAGU- || ||||||| || ----GGGGAAUCAGCAGC-CAG TLE2 hsa-miR-565 56 81 -UUUGUCUGUAG---CGCUCGGUCGG- ::||||||||| || |||| ||| AGGACAGACAUCCUAGC-AGCC-GCCU TLE2 hsa-miR-571 110 129 GAG-UGAGUCUACCGGUUGAGU || :||| |||||||| AUCUGCUCUC-UGGCCAACG-- TLE2 hsa-miR-575 113 134 -CGAG-GACAGGUUGACCGAG- |||| ||| ||||| ||||: UGCUCUCUGGCCAAC-GGCUUC TLE2 hsa-miR-586 171 198 -CCUGGA----UUUUUAUGUUACGUAU |||||| ::||||| ||||:|| GGGACCUCGGUGGAAAUAAAAUGUAUC TLE2 hsa-miR-588 110 128 CAAGAUUGGGUAACACCGGUU- ||| :|:| ||||||| -AUCU-GCUCUC--UGGCCAAC TLE2 hsa-miR-595 118 143 UCUGUGUGG-UGCCG---UGU-GAAG- | :|| ||||| ||| |||| --UCUGGCCAACGGCUUCACACCUUCC TLE2 hsa-miR-596 142 173 -GGGC--------UCCUCGG---CCCGUCCGAA ||:| :||:||| ||||||| CCCUGCUGCAUGUGGGGGCCGAUGGGCAGGG-- TLE2 hsa-miR-601 77 103 GAGGA-GGUUGUUA-GGAUC--UGGU- ||| |||:| ||||| |||: -GCCUCCCAGCCCUGCCUAGGAACCGU TLE2 hsa-miR-604 35 57 CAGGA---CUUAAGGCGUCGGA ||| |:| || |||||| CUCCCAGGGGAAUCAGCAGCCA TLE2 hsa-miR-608 70 95 UGCCUCGAC--AGGGUUGUGGUGGGGA | ||| | |||||:| || ||: -AGCAGCCGCCUCCCAGC-CCUGCCUA TLE2 hsa-miR-612 69 97 UUCCUCGAGUCU----UCGGGACGGGUCG || ||| |: |||||||||:|| UAGCAGC-CGCCUCCCAGCCCUGCCUAGG TLE2 hsa-miR-615 165 186 -UC-UCCCUCUGGGUCCGAGCCU- :| |||| ||||: ||: ||| GGGCAGGG-GACCUCGGU--GGAA TLE2 hsa-miR-619 40 60 UGACCCGUGU-UUGUACAGGUCCAG ||| | |:|| ||||| --AGGGGAAUCAGCAG--CCAGGA- TLE2 hsa-miR-623 122 161 UGGGUUGUCG-----------GGGACGU------UCCCUA |||||:|| |||||| :|||: -GCCAACGGCUUCACACCUUCCCCUGCUGCAUGUGGGGGC TLE2 hsa-miR-625 127 147 UCCUGAUAUCUUGAAAGGGGGA |:|| || ||||||: -CGGCUUCAC-ACCUUCCCCUG TLE2 hsa-miR-632 35 58 -AGGGUGUCCU---UCGUCUGUG ||||| :||| ||||| || CUCCCAGGGGAAUCAGCAGCCAG TLE2 hsa-miR-638 73 111 UCCGGCGGUGGG-CGGG-CGC------------UAGGGA |||||| ||| |||| || ||||| -AGCCGCCUCCCAGCCCUGCCUAGGAACCGUACAUCCCA TLE2 hsa-miR-644 113 133 -CGAGAUUCUUUCGGUG--UGA- ||||| :|||| :|| UGCUCUCU---GGCCAACGGCUU TLE2 hsa-miR-645 68 98 AGUCGUCA-UGGU---------CGGAUCU- :||||| :|| ||||||: CUAGCAGCCGCCUCCCAGCCCUGCCUAGGA TLE2 hsa-miR-646 36 56 CGGAGUCUCC---GUCGACGAA || |||:|| |||| || UCC-CAGGGGAAUCAGCAGCC- TLE2 hsa-miR-647 40 58 CUUCCUUCACUCACGUCGGUG ::|||| ||||||| AGGGGAAUCA---GCAGCCAG TLE2 hsa-miR-650 65 84 CAGGACUCUCG-CGACGGAGGA |||| ||| || |||||| AUCCU---AGCAGCCGCCUCCC TLE2 hsa-miR-658 121 150 -UGGUUGCCUGGAU----GAAGGGAGGCGG- :||||||| |:| |||||| |:||: GGCCAACGG-CUUCACACCUUCCC-CUGCUG TLE2 hsa-miR-662 143 176 -GACGA--------CCCGGUGUUGCA---CCCU- ||||| |||||: | | |||| CCUGCUGCAUGUGGGGGCCG-AUGGGCAGGGGAC TLE2 hsa-miR-663 65 95 CGCCAGGG-CGCCG---------CGGGGCGGA- |||: || || ||||:|||| ---AUCCUAGCAGCCGCCUCCCAGCCCUGCCUA TLE2 hsa-miR-668 152 177 -CAUCACCCGGCU---CGGCUCACUGU ||:| ||||||| || |:| ||| UGUGG-GGGCCGAUGGGCAGGG-GACC TLE2 hsa-miR-675 113 140 GUGACAC-CCGGGA---GAGGCGUGGU :|| |||| ||:| |||| UGCUCUCUGGCCAACGGCUUCACACCU TLE2 hsa-miR-765 134 153 GUAGUGGAAGGAAGAGGAGGU- |||||||| || || || --ACACCUUCCC-CUGCUGCAU TLE2 hsa-miR-766 155 175 CGACUCCGACACCCCGACCUCA |:||| |||| ||:| --GGGGGCCGAUGGGCAGGGGA TLE2 hsa-miR-767-3p 145 173 UCUUUGG----UACCCCA---UACUCGUCU- :|: :||||| |||:||||: ---UGCUGCAUGUGGGGGCCGAUGGGCAGGG TLE2 hsa-miR-769-3p 51 73 -UUGGUUCUGGGGCCUCUAGGGUC- |:|||:||| || ||||:|| CAGCCAGGACA---GACAUCCUAGC TLE2 hsa-let-7a 97 120 UUGAUAUGUUGGAU-GAUG-GAGu ||| :|||| || | ||:| ||| AACCGTACATCCCATCTGCTCTCt TLE2 hsa-let-7b 76 95 uuGGUGUGUUGGAUGAUGGAgu || | ||:|| ||:||| cgCCTCCCAGCC--CTGCCTag TLE2 hsa-let-7c 97 120 UUGGUAUGUUGGAU-GAUG-GAGu ||||:|||| || | ||:| ||| AACCGTACATCCCATCTGCTCTCt TLE2 hsa-miR-10a 152 174 guguuuaaGCCUAGAUGUCCCau | ||| :||||| tgtgggggCCGATGGGCAGGGga TLE2 hsa-miR-125a 161 184 guguCCAAUUUCCCAGAGUC-CCU || |::|| |||:| ||| cgatGGGCAGGGGACCTCGGTGGA TLE2 hsa-miR-127 140 163 ucGGUUCGA-GU-CUGCCUAGGCU || ||| || | ||: |||| tcCCCTGCTGCATGTGGGGGCCGA TLE2 hsa-miR-133a 159 178 uGUCGACCAACUUCCCCUGGuu | | ||| | |||||||| gCCGATGG--GCAGGGGACCtc TLE2 hsa-miR-133b 160 178 auCGACCAACUUCCCCUGGuu | ||| | |||||||| ccGATGG--GCAGGGGACCtc TLE2 hsa-miR-134 115 136 GGGAGACCAGUUGGUC--AGUGU |:|||||| ||| |:| ||||| CTCTCTGGCCAA-CGGCTTCACA TLE2 hsa-miR-135a 36 58 AGUGUAUCCUUAUUUUUCGGUau || || :||||| |: ||||| TCCCAGGGGAATCAGCAGCCAgg TLE2 hsa-miR-135b 37 58 GUGUAUCCUUACUUUUCGGUau | || :||||| |: ||||| CCCAGGGGAATCAGCAGCCAgg TLE2 hsa-miR-150 142 160 GUGACCAUGUUCCCAACCCUCu | ||| |:|| | ||||:| CCCTGCTGCATG---TGGGGGc TLE2 hsa-miR-181a* 157 184 CCAUGUUA---GUUGCC---AGCUACCa || |:|| ||: || |||:||| GGGCCGATGGGCAGGGGACCTCGGTGGa TLE2 hsa-miR-188 155 176 ugggaGGUGGUACGUUCCCUac ||: :: |||:|||| gggggCCGATGGGCAGGGGAcc TLE2 hsa-miR-18a* 152 171 uCUUCCUCGUGAAUCCCGUCa | :||:|| | |||||| tGTGGGGGC-CGATGGGCAGg TLE2 hsa-miR-191* 55 78 ccCCUG-CUUUAGGUUCG-CGUCG |||| || |||| ||| || || caGGACAGACATCCTAGCAGCCGC TLE2 hsa-miR-193b 143 165 uuuCGCCCUGAAACUCCCGGUCAa || | | | ||:|||||: | cctGCTGCA-TGTGGGGGCCGATg TLE2 hsa-miR-198 107 125 GGAUAGAGGGGAGACCUGg || |||| |:|||||| | CCCATCTGCTCTCTGGCCa TLE2 hsa-miR-206 123 143 GGUGUG-UGAAG-GAAUGUAAGGu ||| || :|||| | || |||| CCA-ACGGCTTCAC--ACCTTCCc TLE2 hsa-miR-214 134 150 gacGGACAGACACGGACGACa ||| || ||||||| acaCCT-TC---CCCTGCTGc TLE2 hsa-miR-221 171 198 CUUUGG-GUCGUC----UGUUACAUCGA |::||| |:|::| | |||||| || GGGACCTCGGTGGAAATAAAATGTATCT TLE2 hsa-miR-296 146 163 uGUCCUAACUCCCCCCCGGga | | || | ||||||| gCTGCAT---GTGGGGGCCga TLE2 hsa-miR-296 154 183 uguCCUAACU-CCC--CCCCGGGA------ ||: || ||| |||| ||| tggGGGCCGATGGGCAGGGGACCTCGGTGG TLE2 hsa-miR-324-3p 143 173 GGUCGUCGUGGAC---------CCCGUCACC || || |||: || |||||| || CCTGCTGCATGTGGGGGCCGATGGGCAGGGG TLE2 hsa-miR-328 141 163 ugccuuccCGU-CUCUCCCGGuc ||| | |:||||| cccctgctGCATGTGGGGGCCga TLE2 hsa-miR-331 28 45 aAGAUCCUAUCCGGGUCCCCg || || | |||||||| gTCCAG---ACTCCCAGGGGa TLE2 hsa-miR-331 156 174 aagaucCUAUCCGGGUCCCCg |||:|| |||||| ggggccGATGGG--CAGGGGa TLE2 hsa-miR-339 154 173 ACUCGAGGACCUCCUGUCCCu ||:| || | ||:||||| TGGGGGCC-GATGGGCAGGGg TLE2 hsa-miR-345 36 52 cGGGACCUGAUCCUCAGUCGU ||| || ||| |||||| tCCCAGG----GGAATCAGCA TLE2 hsa-miR-346 152 173 uCUCCGUCCGUACGCCCGUCugu | || :||| :|||||| tGTGG-GGGCCGATGGGCAGggg TLE2 hsa-miR-34a 70 93 UUGUUGGUCGA--UUCUGUGACGGu |:||:||: || || | ||||| AGCAGCCGCCTCCCAG-CCCTGCCt TLE2 hsa-miR-34b 72 94 GUUAGUCGAUUACUGUGACGGAU ||: |: || :| ||||||| CAGCCGCCTCCCAGCCCTGCCTA TLE2 hsa-miR-363* 188 208 UUUAACGUAGCACUAG-GUGGGC ||| ||:||| | ||| ||:||| AAAATGTATC-T-ATCACATCCG TLE2 hsa-miR-370 30 55 GGUCCAAGG-----UGGGGUCGUCcg |||| ||| : :|||||| CCAGACTCCCAGGGGAATCAGCAGcc TLE2 hsa-miR-370 54 76 GGUCCAAG---GUGGGGUCGUCCG ||||| | ||:||:||||| | CCAGG-ACAGACATCCTAGCAGCC TLE2 hsa-miR-378 152 173 uguguCCUGGACCUCAGUCCUC ||:|| :| ||||:| tgtggGGGCCGATGGGCAGGGG TLE2 hsa-miR-412 163 186 UGCCGAUCACCUGG-UCCACUUca |:|| || ||||| ||||:| ATGGGCAGGGGACCTCGGTGGAaa TLE2 hsa-miR-422a 10 33 ccGGAA-GAC-UGGGAUUCAGGUC |||| ||| |||| |||||||| ccCCTTCCTGTACCCGAAGTCCAG TLE2 hsa-miR-422b 10 33 ccGGAA-GAC-UGAGGUUCAGGUC |||| ||| || | |||||||| ccCCTTCCTGTACCCGAAGTCCAG TLE2 hsa-miR-449 74 93 uGGUCGAUUGUUAUGUGACGGu ||: || || :| ||||| gCCGCCTCCCA--GCCCTGCCt TLE2 hsa-miR-449b 74 93 CGGUCGAUUGUUAUGUGACGGA |||: || || :| |||||| GCCGCCTCCCA--GCCCTGCCT TLE2 hsa-miR-453 42 70 gCUUGAGU----GG---UGCCUGUUGGAg |:| ||| || || |||| ||| gGGAATCAGCAGCCAGGACAGACATCCTa TLE2 hsa-miR-485-5p 59 82 cuuaaGUAGUGCCG--GUCGGAGa |||| : || | ||||| acagaCATCCTAGCAGCCGCCTCc TLE2 hsa-miR-486 35 64 GAG---CCCC---GUCG--AGUCAUGUCcu ||| |||| |||| ||| |||| CTCCCAGGGGAATCAGCAGCCAGGACAGac TLE2 hsa-miR-493-3p 163 180 gACCGUGUGUCAUCUGGAagu ||| :||| :||||| aTGG---GCAGGGGACCTcgg TLE2 hsa-miR-502 154 174 AUCGUGGGUCUA-UCGUUCCua |:| : || ||| :|||:|| TGGGGGCC-GATGGGCAGGGga TLE2 hsa-miR-503 88 117 GACG---UCUUGACA---AGGG-CGACGAu |||| :|||| || |||| ||||| CTGCCTAGGAACCGTACATCCCATCTGCTc TLE2 hsa-miR-504 152 175 uauCUCACGUCUG---GUCCCaga |:| || ||: ||||| tgtGGGGGCCGATGGGCAGGGgac TLE2 hsa-miR-513 1 23 uaUUUACU--GUGGAGGGACAcuu | |||| | |||:||||| -gACATGACCCCCCTTCCTGTacc TLE2 hsa-miR-520a* 94 124 UCUUU--CAUGAAGG--------GAGACCuc ||:|| |||| ||| |||||| AGGAACCGTACATCCCATCTGCTCTCTGGcc TLE2 hsa-miR-524 34 58 UGAGGUUUCCCU---UCG-CGGaag ||||| |:|||| ||| ||| ACTCCCAGGGGAATCAGCAGCCagg TLE2 hsa-miR-525 94 124 UCUUU--CACGUAGG--------GAGACCuc ||:|| || ||||| |||||| AGGAACCGTACATCCCATCTGCTCTCTGGcc TLE2 hsa-miR-557 165 187 uCUGUUCCGGGUGGGCACGUUUg |:||:|| | :| ||| ||| gGGCAGGGGACCTCGGTGGAAAt TLE2 hsa-miR-558 38 57 uaaaaCCAU-GUCGUCGagu || | ||||||| ccaggGGAATCAGCAGCcag TLE2 hsa-miR-565 57 79 uuUGUCUGUAG---CGCUCGGUCGG ||||||||| || |||| ||| ggACAGACATCCTAGC-AGCC-GCC TLE2 hsa-miR-571 112 130 GA-GUGAGUCUACCGGUUGagu || | ||| |||||||| CTGCTCTC---TGGCCAACggc TLE2 hsa-miR-575 114 132 CGAG-GACAGGUUGACCGAg |||| ||| ||||| |||| GCTCTCTGGCCAAC-GGCTt TLE2 hsa-miR-586 172 197 CCUGG----AUUUUUAUGUUACGUAu ||||| |::||||| ||||:|| GGACCTCGGTGGAAATAAAATGTATc TLE2 hsa-miR-588 101 126 CAAGAUUGGGUA------ACACCGGUU || | | ||||| | ||||||| GTAC-ATCCCATCTGCTCTCTGGCCAA TLE2 hsa-miR-595 116 141 ucuguguGG-UGCC---GUGU-GAAG || |||| |||| |||| tctctggCCAACGGCTTCACACCTTC TLE2 hsa-miR-596 150 174 GGGC-UCCUCGG---CCCGUCCgaa | :| :||:||| ||||||| CATGTGGGGGCCGATGGGCAGGgga TLE2 hsa-miR-601 76 101 GAGGA-GGUUGUUA-GGAUC--UGGu | ||| |||:| | ||||| ||| CGCCTCCCAGCCCTGCCTAGGAACCg TLE2 hsa-miR-608 55 82 ugCCUCGAC---AGGGUUGU-GGUGGGGa ||| | | |||:|:|| ||:||:| caGGA-CAGACATCCTAGCAGCCGCCTCc TLE2 hsa-miR-615 154 181 uCUCCC-----UCUGGGUCC--GAGCCu |:||| :|:| :|| ||||| tGGGGGCCGATGGGCAGGGGACCTCGGt TLE2 hsa-miR-619 39 60 ugaCCCGUGUUUGUACAGGUCCag ||| |: |:|| ||||| cagGGGAATCAGCAG--CCAGGac TLE2 hsa-miR-623 151 175 uggguuguCGGGGA--CGUUCCCUa ||| | |||:|||| atgtggggGCCGATGGGCAGGGGAc TLE2 hsa-miR-623 106 131 uGGGUUGUCG-GGGAC--GUUCCCua |||| | || |:||| ||| || tCCCATCTGCTCTCTGGCCAACGGct TLE2 hsa-miR-625 126 146 UCCUGAUAUCUUGAAAGGGGga | |:|| | || |||||| ACGGCT-TCACACCTTCCCCtg TLE2 hsa-miR-632 36 57 AGGGUGUCCU---UCGUCUGUg ||||| :||| ||||| || TCCCAGGGGAATCAGCAGCCAg TLE2 hsa-miR-638 72 110 ucCGGCGGUGGG-CGGG-------C---GC---UAGGGa |||||| ||| |||| | || ||||| caGCCGCCTCCCAGCCCTGCCTAGGAACCGTACATCCCa TLE2 hsa-miR-644 114 138 CGAGAUUC---UU-UCG--GUGUGa ||||| | || :|| ||||| GCTCTCTGGCCAACGGCTTCACACc TLE2 hsa-miR-645 82 96 aGUCGUCAUGGUCGGAUCu |||| || |||||| cCAGC----CCTGCCTAGg TLE2 hsa-miR-645 50 72 aGUC-GUCAUG---GUCGGAUCu ||| ||| || || ||||| gCAGCCAGGACAGACATCCTAGc TLE2 hsa-miR-646 36 56 cGGAGUCUCC---GUCGACGaa || |||:|| |||| || tCC-CAGGGGAATCAGCAGCca TLE2 hsa-miR-647 39 57 cUUCCUUCACUCACGUCGGUg |:||:| | | ||||||| cAGGGGAATCA--GCAGCCAg TLE2 hsa-miR-647 54 78 cuUCCU-UCACU--CA-CGUCGGUG |||| || | | ||||||:| ccAGGACAGACATCCTAGCAGCCGC TLE2 hsa-miR-658 122 148 uGGUUGCCUGGA---UGAAGGGAGGCGg ||||||| |:| || |:|| |:|| gCCAACGG-CTTCACACCTTCCCCTGCt TLE2 hsa-miR-662 144 158 GACGACCCGGUGUUGCACCCu |||||| | |:||||| CTGCTG-----C-ATGTGGGg TLE2 hsa-miR-663 71 93 CGCCAGGGCGCCG---CGGGGCGGA || | |||| | ||||:|||| GCAG--CCGCCTCCCAGCCCTGCCT TLE2 hsa-miR-668 153 176 CAUCACCCGGCU---CGGCUCACUGu ||:| ||||||| || |:| ||| GTGG-GGGCCGATGGGCAGGG-GACc TLE2 hsa-miR-675 115 139 GUGACACCCG--GGAGAGGCGUGGu | || ||| | | ||:| |||| CTCTCTGGCCAACGGCTTCACACCt TLE2 hsa-miR-765 124 145 GUAGUGGAAG-GAAGAGGAGGu || |: |||| | ||:| || CAACGGCTTCACACCTTCCCCt TLE2 hsa-miR-766 153 174 CGACUCCGACACCCCGACCUCa |: |:||| | |||| ||:| GTGGGGGCCGATGGGCAGGGGa TLE2 hsa-miR-767-3p 144 171 ucuuugGUA---CCCC--AUACUCGUCu ||| |||| |||:|||| ctgctgCATGTGGGGGCCGATGGGCAGg TLE2 hsa-miR-769-3p 52 71 UUGGUUCUGGGGCCUCUAGGGUC |:|||:|| | || ||||:|| AGCCAGGA---CAGACATCCTAG

DNA & RNA Element - miRcode Gene Name Type microRNA Seed Position Seed Type Total Cons% Tr Region TLE2 High_conserved miR-503 chr19:3005484 7-mer-m8 58 CDS TLE2 High_conserved miR-133abc chr19:3013810 7-mer-m8 33 CDS, 5pUTR TLE2 High_conserved miR-135ab/135a-5p chr19:3029601 7-mer-m8 9 5pUTR TLE2 High_conserved miR-138/138ab chr19:3006098 7-mer-m8 7 CDS TLE2 High_conserved miR-141/200a chr19:3006127 7-mer-m8 7 CDS TLE2 High_conserved miR-146ac/146b-5p chr19:3028766 7-mer-m8 36 CDS, 5pUTR TLE2 High_conserved miR-148ab-3p/152 chr19:3006600 7-mer-m8 11 CDS TLE2 High_conserved let-7/98/4458/4500 chr19:3019527 7-mer-m8 11 5pUTR TLE2 High_conserved miR-18ab/4735-3p chr19:3005886 7-mer-m8 27 CDS TLE2 High_conserved miR-18ab/4735-3p chr19:3011034 7-mer-m8 0 CDS TLE2 High_conserved miR-190/190ab chr19:3028945 7-mer-A1 4 5pUTR TLE2 High_conserved miR-192/215 chr19:3006118 7-mer-A1 11 CDS TLE2 High_conserved miR-193/193b/193a-3p chr19:3011068 7-mer-m8 18 CDS TLE2 High_conserved miR-214/761/3619-5p chr19:2997696 7-mer-m8 27 3pUTR TLE2 High_conserved miR-214/761/3619-5p chr19:3005769 7-mer-m8 53 CDS TLE2 High_conserved miR-22/22-3p chr19:3006565 7-mer-m8 47 CDS TLE2 High_conserved miR-23abc/23b-3p chr19:3028362 7-mer-m8 40 CDS, 5pUTR TLE2 High_conserved miR-24/24ab/24-3p chr19:3025427 7-mer-m8 9 5pUTR TLE2 High_conserved miR-25/32/92abc/363/363-3p/367 chr19:3045776 7-mer-m8 7 CDS TLE2 High_conserved miR-31 chr19:3028956 7-mer-m8 0 5pUTR TLE2 High_conserved miR-103a/107/107ab chr19:2997695 7-mer-A1 13 3pUTR TLE2 High_conserved miR-103a/107/107ab chr19:3005768 7-mer-A1 58 CDS TLE2 High_conserved miR-34ac/34bc-5p/449abc/449c-5p chr19:3002479 7-mer-m8 38 CDS TLE2 High_conserved miR-383 chr19:3005909 7-mer-m8 16 CDS TLE2 High_conserved miR-455-5p chr19:3019561 7-mer-m8 7 5pUTR TLE2 Medium_conserved miR-504/4725-5p chr19:3008908 7-mer-A1 20 CDS TLE2 Medium_conserved miR-504/4725-5p chr19:3029040 7-mer-m8 2 5pUTR TLE2 Medium_conserved miR-544/544ab/544-3p chr19:3005733 7-mer-m8 44 CDS TLE2 Medium_conserved miR-615-3p chr19:2997883 7-mer-m8 31 3pUTR, CDS TLE2 Medium_conserved miR-134/3118 chr19:3011065 7-mer-m8 42 CDS TLE2 Medium_conserved miR-873 chr19:3005940 7-mer-m8 13 CDS TLE2 Medium_conserved miR-873 chr19:3025026 7-mer-A1 42 CDS, 5pUTR TLE2 Medium_conserved miR-876-5p/3167 chr19:3025603 7-mer-m8 2 5pUTR TLE2 Medium_conserved miR-136 chr19:3002447 8-mer 60 CDS TLE2 Medium_conserved miR-28-5p/708/1407/1653/3139 chr19:3009601 8-mer 49 CDS TLE2 Medium_conserved miR-296-3p chr19:3013806 7-mer-m8 31 CDS, 5pUTR TLE2 Medium_conserved miR-324-5p chr19:3006604 7-mer-A1 9 CDS TLE2 Medium_conserved miR-328a/328b-3p chr19:3005567 7-mer-m8 56 CDS TLE2 Medium_conserved miR-328a/328b-3p chr19:3006446 7-mer-A1 16 CDS TLE2 Medium_conserved miR-328a/328b-3p chr19:3025487 7-mer-A1 2 5pUTR TLE2 Medium_conserved miR-329/329ab/362-3p chr19:3019602 7-mer-m8 11 5pUTR TLE2 Medium_conserved miR-339b/339-5p/3586-5p chr19:3005509 7-mer-m8 27 CDS TLE2 Medium_conserved miR-342-3p chr19:3028361 7-mer-A1 53 CDS, 5pUTR TLE2 Medium_conserved miR-370 chr19:3015758 7-mer-A1 40 CDS, 5pUTR TLE2 Medium_conserved miR-370 chr19:3019758 7-mer-m8 56 CDS, 5pUTR TLE2 Medium_conserved miR-377 chr19:3006476 8-mer 11 CDS TLE2 Medium_conserved miR-378/422a/378bcdefhi chr19:2997812 8-mer 11 3pUTR TLE2 Medium_conserved miR-378/422a/378bcdefhi chr19:3013722 7-mer-m8 31 CDS, 5pUTR TLE2 Medium_conserved miR-378/422a/378bcdefhi chr19:3019282 7-mer-A1 24 CDS, 5pUTR TLE2 Medium_conserved miR-379/1193-5p/3529 chr19:3019529 7-mer-m8 11 5pUTR TLE2 Medium_conserved miR-384/384-3p chr19:2997747 7-mer-m8 11 3pUTR TLE2 Medium_conserved miR-411 chr19:2997847 7-mer-m8 40 3pUTR, CDS TLE2 Medium_conserved miR-485-5p/1698/1703/1962 chr19:3009590 7-mer-m8 42 CDS TLE2 Medium_conserved miR-485-5p/1698/1703/1962 chr19:3013718 7-mer-m8 31 CDS, 5pUTR TLE2 Medium_conserved miR-485-5p/1698/1703/1962 chr19:3019702 8-mer 38 CDS, 5pUTR TLE2 Medium_conserved miR-485-5p/1698/1703/1962 chr19:3028376 8-mer 31 CDS, 5pUTR TLE2 Medium_conserved miR-485-5p/1698/1703/1962 chr19:3028969 7-mer-m8 2 5pUTR TLE2 Medium_conserved miR-485-5p/1698/1703/1962 chr19:3028991 7-mer-m8 4 5pUTR TLE2 Medium_conserved miR-491-5p chr19:3028986 7-mer-m8 0 5pUTR TLE2 Medium_conserved miR-494 chr19:3025436 7-mer-A1 9 5pUTR

DNA & RNA Element - RAID2 Gene Name RAID ID Interactor 1 Category 1 ID 1 Interactor 2 Category 2 ID 2 Methods Score TLE2 RAID00655917 hsa-miR-214-3p miRNA MIMAT0000271 TLE2 mRNA 7089 Prediction 0.1828 TLE2 RAID00935468 hsa-miR-214-5p miRNA MIMAT0004564 TLE2 mRNA 7089 Prediction 0.1828 TLE2 RAID00941899 hsa-miR-578 miRNA MIMAT0003243 TLE2 mRNA 7089 Prediction 0.1828 TLE2 RAID00983919 hsa-miR-422a miRNA MIMAT0001339 TLE2 mRNA 7089 Prediction 0.1828 TLE2 RAID01629327 hsa-miR-4764-5p miRNA MIMAT0019914 TLE2 mRNA 7089 Prediction 0.1828 TLE2 RAID01959782 hsa-miR-411-5p miRNA MIMAT0003329 TLE2 mRNA 7089 Prediction 0.2202 TLE2 RAID02209639 hsa-miR-143-3p miRNA MIMAT0000435 TLE2 mRNA 7089 Prediction 0.1828 TLE2 RAID02298469 hsa-miR-1909-3p miRNA MIMAT0007883 TLE2 mRNA 7089 Prediction 0.1828 TLE2 RAID02399171 hsa-miR-615-3p miRNA MIMAT0003283 TLE2 mRNA 7089 Prediction 0.2202 TLE2 RAID02586057 hsa-miR-539-3p miRNA MIMAT0022705 TLE2 mRNA 7089 Prediction 0.1828 TLE2 RAID02670142 hsa-miR-6722-3p miRNA MIMAT0025854 TLE2 mRNA 7089 Prediction 0.1828 TLE2 RAID02700350 hsa-miR-3129-5p miRNA MIMAT0014992 TLE2 mRNA 7089 Prediction 0.1828 TLE2 RAID02800121 hsa-miR-4435 miRNA MIMAT0018951 TLE2 mRNA 7089 Prediction 0.1828 TLE2 RAID03287542 hsa-miR-378a-3p miRNA MIMAT0000732 TLE2 mRNA 7089 Prediction 0.1828 TLE2 RAID03357177 hsa-miR-2278 miRNA MIMAT0011778 TLE2 mRNA 7089 Prediction 0.1828 TLE2 RAID05210806 CRNDE lncRNA 643911 TLE2 protein 7089 Microarray//RNA-seq 0.6606