AURKA
Drug & target - TTD
NameType of TargetSynonymsDiseaseDrugsInhibitorAntibody
Aurora kinase AClinical trial targetAurora/IPL1-related kinase 1;Aurora-A;Aurora-related kinase 1;Breast tumor-amplified kinase;hARK1;Serine/threonine kinase 15;Serine/threonine-protein kinase 6Colorectal cancer;Lymphoma;Solid tumorsAMG 900;VX-680;MLN8054;VX-689;VX-689;PF-03814735;PHA-680632;R763;R763;AT9283;PHA-739358;SNS-314;MK-5108;ENMD-2076;CYC116;SU-6668;ABT-348;ABT-348;ABT-348;AZD1152;AZD1152;TAS-119;MLN8237VX-680;MLN8054;4-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine;VX-689;PF-03814735;Indirubin-3-oxime;PHA-680632;R763;2-(1H-pyrazol-3-yl)-1H-benzimidazole;AT9283;Adenosine-5'-Diphosphate;AZD-1152-HQPA;PHA-739358;Indirubin-3-acetoxime;SNS-314;MK-5108;6-bromoindirubin-3-oxime;Phosphonothreonine;ZM-447439;ENMD-2076;CYC116;SU-6668;Indirubin-3-methoxime;AZD1152;TAS-119;7-fluoroindirubin-3-oxime;MLN8237
Aurora protein kinaseClinical trial targetCancerMK-6592;HPP-6072np8;quinazoline deriv. 1;MK-6592;compound 46;HPP-607;Glycyl-H 1152;compound 10;compound 16;K00244;BMS-739562;compound 25;SNS-314 prodrugs;BPR1K-0224;MP-529
Drug & target - GRAC
aurora kinase A enzyme 557 Aurora kinase (Aur) family 1936 20q13
Drug & target - PDTD
Ensembl_gene_ID UniProt ID PDB Code
ENSG00000087586.17 O14965 1MUO