Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 12 121870066 rs7316497 C T rs7316497 0.000163 METHIONINE CASPASE 1|CASPASE 9|CASP9 PROTEIN, HUMAN|5'-METHYLTHIOADENOSINE|APIP PROTEIN, HUMAN|DEOXYADENOSINES|THIONUCLEOSIDES|APOPTOSIS REGULATORY PROTEINS Salmonella-induced pyroptosis NA NA T intron GWASdb_drug 12 122013607 rs28468612 G A rs28468612 7.65E-04 GEMCITABINE|CYTARABINE MANNOSYLTRANSFERASES|PIGB PROTEIN, HUMAN|RNA, SMALL INTERFERING|DEOXYCYTIDINE Response to cytidine analogues (gemcitabine) HPOID:0002664 DOID:162 G intron GWASdb_drug 12 121870066 rs7316497 C T rs7316497 0.000163 Salmonella-induced pyroptosis NA NA T intron GWASdb_trait 12 121870922 rs12427382 G A rs12427382 6.42E-05 Type 2 diabetes HPOID:0005978 DOID:9352 G intron GWASdb_trait 12 121871006 rs11065575 A C rs11065575 6.42E-05 Type 2 diabetes HPOID:0005978 DOID:9352 A intron GWASdb_trait 12 121874019 rs9634167 C T rs9634167 7.44E-05 Type 2 diabetes HPOID:0005978 DOID:9352 T intron GWASdb_trait 12 121876257 rs10444489 G T rs10444489 7.44E-05 Type 2 diabetes HPOID:0005978 DOID:9352 T intron GWASdb_trait 12 121877487 rs11065576 G A rs11065576 7.44E-05 Type 2 diabetes HPOID:0005978 DOID:9352 G intron GWASdb_trait 12 121878659 rs1064951 C T rs1064951 7.44E-05 Type 2 diabetes HPOID:0005978 DOID:9352 G cds-synon GWASdb_trait 12 121879111 rs2288154 G C rs2288154 7.44E-05 Type 2 diabetes HPOID:0005978 DOID:9352 C intron GWASdb_trait 12 121879592 rs11065577 C T rs11065577 7.44E-05 Type 2 diabetes HPOID:0005978 DOID:9352 C intron GWASdb_trait 12 121879685 rs11065578 C G rs11065578 7.44E-05 Type 2 diabetes HPOID:0005978 DOID:9352 G intron GWASdb_trait 12 121879702 rs11065579 C A rs11065579 7.44E-05 Type 2 diabetes HPOID:0005978 DOID:9352 C intron GWASdb_trait 12 121880520 rs3751131 G A rs3751131 7.44E-05 Type 2 diabetes HPOID:0005978 DOID:9352 C cds-synon GWASdb_trait 12 121882471 rs3817549 G C rs3817549 7.44E-05 Type 2 diabetes HPOID:0005978 DOID:9352 G intron GWASdb_trait 12 121882819 rs3817544 T C rs3817544 7.44E-05 Type 2 diabetes HPOID:0005978 DOID:9352 G intron GWASdb_trait 12 121892786 rs10849888 A G rs10849888 3.46E-04 Type 2 diabetes HPOID:0005978 DOID:9352 G intron GWASdb_trait 12 121893020 rs10744764 G A rs10744764 7.44E-05 Type 2 diabetes HPOID:0005978 DOID:9352 G intron GWASdb_trait 12 121897098 rs10849889 C T rs10849889 7.44E-05 Type 2 diabetes HPOID:0005978 DOID:9352 C intron GWASdb_trait 12 121900000 rs3817543 T C rs3817543 7.44E-05 Type 2 diabetes HPOID:0005978 DOID:9352 A intron GWASdb_trait 12 121903971 rs11065585 G C rs11065585 7.44E-05 Type 2 diabetes HPOID:0005978 DOID:9352 G intron GWASdb_trait 12 121908509 rs10774598 A G rs10774598 7.44E-05 Type 2 diabetes HPOID:0005978 DOID:9352 A intron GWASdb_trait 12 121911602 rs10849891 T G rs10849891 7.44E-05 Type 2 diabetes HPOID:0005978 DOID:9352 T intron GWASdb_trait 12 121927603 rs7316418 G A rs7316418 8.46E-05 Parkinson's disease HPOID:0001300 DOID:14330 G intron GWASdb_trait 12 121933663 rs11065598 C T rs11065598 2.66E-05 Parkinson's disease HPOID:0001300 DOID:14330 T intron GWASdb_trait 12 121938185 rs10849893 C G rs10849893 2.00E-06 Fasting glucose-related traits (interaction with BMI) HPOID:0003162 DOID:9352 C intron GWASdb_trait 12 122013607 rs28468612 G A rs28468612 7.65E-04 Response to cytidine analogues (gemcitabine) HPOID:0002664 DOID:162 G intron GWASdb_trait

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000089094.17 KDM2B 609078