Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change BLCA 14 24686377 24686377 + Missense_Mutation SNP G G A TCGA-K4-A6FZ-01A-11D-A31L-08 TCGA-K4-A6FZ-10A-01D-A31J-08 g.chr14:24686377G>A c.202C>T c.(202-204)Cac>Tac p.H68Y BLCA 14 24687356 24687356 + Silent SNP G G A TCGA-H4-A2HQ-01A-11D-A17V-08 TCGA-H4-A2HQ-10A-01D-A17V-08 g.chr14:24687356G>A c.132C>T c.(130-132)atC>atT p.I44I BLCA 14 24687622 24687622 + Missense_Mutation SNP C C T TCGA-UY-A8OB-01A-12D-A42E-08 TCGA-UY-A8OB-11A-12D-A42H-08 g.chr14:24687622C>T c.34G>A c.(34-36)Gag>Aag p.E12K BRCA 14 24687410 24687410 + Missense_Mutation SNP G G C TCGA-A2-A0YK-01A-22D-A117-09 TCGA-A2-A0YK-10A-01D-A117-09 g.chr14:24687410G>C c.78C>G c.(76-78)atC>atG p.I26M COADREAD 14 24687414 24687414 + Missense_Mutation SNP C C T TCGA-AG-3892-01A-01W-1073-09 TCGA-AG-3892-10A-01W-1073-09 g.chr14:24687414C>T c.74G>A c.(73-75)cGa>cAa p.R25Q ESCA 14 24686403 24686403 + Missense_Mutation SNP T T A TCGA-LN-A9FP-01A-31D-A387-09 TCGA-LN-A9FP-10A-01D-A38A-09 g.chr14:24686403T>A c.176A>T c.(175-177)tAc>tTc p.Y59F ESCA 14 24687342 24687342 + Missense_Mutation SNP T T C TCGA-LN-A49U-01A-31D-A27G-09 TCGA-LN-A49U-10A-01D-A27G-09 g.chr14:24687342T>C c.146A>G c.(145-147)cAg>cGg p.Q49R GBMLGG 14 24687634 24687634 + Silent SNP G G A TCGA-RY-A840-01A-11D-A36O-08 TCGA-RY-A840-10A-01D-A367-08 g.chr14:24687634G>A c.22C>T c.(22-24)Ctg>Ttg p.L8L HNSC 14 24686415 24686415 + Missense_Mutation SNP G G C TCGA-DQ-5625-01A-01D-1870-08 TCGA-DQ-5625-10A-01D-1870-08 g.chr14:24686415G>C c.164C>G c.(163-165)aCa>aGa p.T55R HNSC 14 24687636 24687636 + Splice_Site SNP G G A TCGA-UF-A719-01A-12D-A34J-08 TCGA-UF-A719-10A-01D-A34M-08 g.chr14:24687636G>A c.20C>T c.(19-21)aCg>aTg p.T7M LGG 14 24687634 24687634 + Silent SNP G G A TCGA-RY-A840-01A-11D-A36O-08 TCGA-RY-A840-10A-01D-A367-08 g.chr14:24687634G>A c.22C>T c.(22-24)Ctg>Ttg p.L8L LUAD 14 24687414 24687414 + Missense_Mutation SNP C C T TCGA-05-4403-01A-01D-1265-08 TCGA-05-4403-10A-01D-1265-08 g.chr14:24687414C>T c.74G>A c.(73-75)cGa>cAa p.R25Q LUAD 14 24687421 24687421 + Splice_Site SNP C C T TCGA-05-4433-01A-22D-1855-08 TCGA-05-4433-10A-01D-1855-08 g.chr14:24687421C>T c.67G>A c.(67-69)Gtg>Atg p.V23M READ 14 24687414 24687414 + Missense_Mutation SNP C C T TCGA-AG-3892-01A-01W-1073-09 TCGA-AG-3892-10A-01W-1073-09 g.chr14:24687414C>T c.74G>A c.(73-75)cGa>cAa p.R25Q

Mutation - ICGC Project Code Chromosome Chromosome Start Chromosome End Mutation Type Mutated from Allele Mutated to Allele Consequence Type AA Mutation CDS Mutation BLCA-CN 14 24682722 24682722 single base substitution A C downstream_gene_variant BLCA-CN 14 24684759 24684759 single base substitution T G downstream_gene_variant BLCA-CN 14 24702539 24702539 single base substitution G A upstream_gene_variant BLCA-US 14 24687356 24687356 single base substitution G A exon_variant BLCA-US 14 24687356 24687356 single base substitution G A intron_variant BLCA-US 14 24687356 24687356 single base substitution G A synonymous_variant I44I 132C>T BRCA-EU 14 24682178 24682178 single base substitution G C downstream_gene_variant BRCA-EU 14 24682619 24682619 single base substitution C T downstream_gene_variant BRCA-EU 14 24682832 24682832 single base substitution G T downstream_gene_variant BRCA-EU 14 24683221 24683221 single base substitution C T downstream_gene_variant BRCA-EU 14 24685224 24685224 single base substitution G A downstream_gene_variant BRCA-EU 14 24685651 24685651 single base substitution G C downstream_gene_variant BRCA-EU 14 24685779 24685779 single base substitution G A downstream_gene_variant BRCA-EU 14 24687375 24687375 insertion of <=200bp - G exon_variant BRCA-EU 14 24687375 24687375 insertion of <=200bp - G frameshift_variant P38P? BRCA-EU 14 24687375 24687375 insertion of <=200bp - G intron_variant BRCA-EU 14 24688405 24688405 single base substitution C T intron_variant BRCA-EU 14 24688405 24688405 single base substitution C T upstream_gene_variant BRCA-EU 14 24692073 24692073 single base substitution C T downstream_gene_variant BRCA-EU 14 24692073 24692073 single base substitution C T intron_variant BRCA-EU 14 24692073 24692073 single base substitution C T upstream_gene_variant BRCA-EU 14 24692606 24692606 deletion of <=200bp A - downstream_gene_variant BRCA-EU 14 24692606 24692606 deletion of <=200bp A - intron_variant BRCA-EU 14 24692606 24692606 deletion of <=200bp A - upstream_gene_variant BRCA-EU 14 24693294 24693294 single base substitution C G downstream_gene_variant BRCA-EU 14 24693294 24693294 single base substitution C G intron_variant BRCA-EU 14 24694594 24694594 single base substitution G A downstream_gene_variant BRCA-EU 14 24694594 24694594 single base substitution G A intron_variant BRCA-EU 14 24697325 24697325 single base substitution C T exon_variant BRCA-EU 14 24697325 24697325 single base substitution C T intron_variant BRCA-EU 14 24697773 24697773 single base substitution T C exon_variant BRCA-EU 14 24697773 24697773 single base substitution T C intron_variant BRCA-EU 14 24698524 24698524 single base substitution C G intron_variant BRCA-EU 14 24699190 24699190 single base substitution C T intron_variant BRCA-EU 14 24700613 24700616 deletion of <=200bp AAAT - intron_variant BRCA-EU 14 24700871 24700871 deletion of <=200bp G - exon_variant BRCA-EU 14 24700871 24700871 deletion of <=200bp G - intron_variant BRCA-EU 14 24701267 24701267 single base substitution G A intron_variant BRCA-EU 14 24701267 24701267 single base substitution G A upstream_gene_variant BRCA-EU 14 24701605 24701605 single base substitution C T 5_prime_UTR_variant BRCA-EU 14 24701605 24701605 single base substitution C T upstream_gene_variant BRCA-EU 14 24701752 24701752 single base substitution G C upstream_gene_variant BRCA-EU 14 24704359 24704359 single base substitution G A upstream_gene_variant BRCA-EU 14 24704799 24704799 single base substitution C G upstream_gene_variant BRCA-EU 14 24704846 24704846 single base substitution T G upstream_gene_variant BRCA-FR 14 24683221 24683221 single base substitution C T downstream_gene_variant BRCA-FR 14 24683734 24683734 single base substitution T G downstream_gene_variant BRCA-FR 14 24685224 24685224 single base substitution G A downstream_gene_variant BRCA-FR 14 24685779 24685779 single base substitution G A downstream_gene_variant BRCA-FR 14 24692073 24692073 single base substitution C T downstream_gene_variant BRCA-FR 14 24692073 24692073 single base substitution C T intron_variant BRCA-FR 14 24692073 24692073 single base substitution C T upstream_gene_variant BRCA-FR 14 24694594 24694594 single base substitution G A downstream_gene_variant BRCA-FR 14 24694594 24694594 single base substitution G A intron_variant BRCA-FR 14 24696851 24696851 single base substitution G A exon_variant BRCA-FR 14 24696851 24696851 single base substitution G A intron_variant BRCA-FR 14 24698524 24698524 single base substitution C G intron_variant BRCA-FR 14 24701267 24701267 single base substitution G A intron_variant BRCA-FR 14 24701267 24701267 single base substitution G A upstream_gene_variant BRCA-FR 14 24704359 24704359 single base substitution G A upstream_gene_variant BRCA-UK 14 24685135 24685135 single base substitution G A downstream_gene_variant BRCA-UK 14 24692511 24692511 single base substitution G A downstream_gene_variant BRCA-UK 14 24692511 24692511 single base substitution G A intron_variant BRCA-UK 14 24692511 24692511 single base substitution G A upstream_gene_variant BRCA-US 14 24683340 24683340 single base substitution T C downstream_gene_variant BRCA-US 14 24683764 24683764 single base substitution A C downstream_gene_variant BRCA-US 14 24684867 24684867 single base substitution C T downstream_gene_variant BRCA-US 14 24687410 24687410 single base substitution G C exon_variant BRCA-US 14 24687410 24687410 single base substitution G C intron_variant BRCA-US 14 24687410 24687410 single base substitution G C missense_variant I26M 78C>G BRCA-US 14 24702445 24702445 single base substitution C T upstream_gene_variant BTCA-JP 14 24683427 24683433 deletion of <=200bp TGCCACC - downstream_gene_variant BTCA-JP 14 24686450 24686450 deletion of <=200bp A - downstream_gene_variant BTCA-JP 14 24686450 24686450 deletion of <=200bp A - intron_variant BTCA-JP 14 24686510 24686510 single base substitution G T downstream_gene_variant BTCA-JP 14 24686510 24686510 single base substitution G T intron_variant BTCA-JP 14 24702832 24702832 single base substitution A G upstream_gene_variant CESC-US 14 24683549 24683549 single base substitution C G downstream_gene_variant CESC-US 14 24684984 24684984 single base substitution G A downstream_gene_variant CLLE-ES 14 24698088 24698088 single base substitution C G intron_variant COAD-US 14 24684996 24684996 single base substitution A C downstream_gene_variant COCA-CN 14 24685131 24685131 single base substitution C A downstream_gene_variant COCA-CN 14 24686420 24686420 single base substitution C A 3_prime_UTR_variant COCA-CN 14 24686420 24686420 single base substitution C A downstream_gene_variant COCA-CN 14 24686420 24686420 single base substitution C A exon_variant COCA-CN 14 24686420 24686420 single base substitution C A missense_variant E53D 159G>T COCA-CN 14 24687604 24687604 single base substitution C G exon_variant COCA-CN 14 24687604 24687604 single base substitution C G intron_variant COCA-CN 14 24687604 24687604 single base substitution C G missense_variant E18Q 52G>C COCA-CN 14 24702979 24702979 single base substitution C G upstream_gene_variant COCA-CN 14 24703270 24703270 single base substitution G T upstream_gene_variant COCA-CN 14 24705034 24705034 single base substitution T G upstream_gene_variant COCA-CN 14 24706174 24706174 single base substitution C A upstream_gene_variant COCA-CN 14 24706504 24706504 single base substitution G A upstream_gene_variant ESAD-UK 14 24682159 24682159 single base substitution G T downstream_gene_variant ESAD-UK 14 24682301 24682301 single base substitution C G downstream_gene_variant ESAD-UK 14 24682412 24682412 single base substitution G A downstream_gene_variant ESAD-UK 14 24688265 24688265 single base substitution A T intron_variant ESAD-UK 14 24688265 24688265 single base substitution A T upstream_gene_variant ESAD-UK 14 24691452 24691452 deletion of <=200bp A - downstream_gene_variant ESAD-UK 14 24691452 24691452 deletion of <=200bp A - intron_variant ESAD-UK 14 24691452 24691452 deletion of <=200bp A - upstream_gene_variant ESAD-UK 14 24691523 24691523 single base substitution T C downstream_gene_variant ESAD-UK 14 24691523 24691523 single base substitution T C intron_variant ESAD-UK 14 24691523 24691523 single base substitution T C upstream_gene_variant ESAD-UK 14 24693884 24693884 single base substitution A G downstream_gene_variant ESAD-UK 14 24693884 24693884 single base substitution A G intron_variant ESAD-UK 14 24694131 24694131 single base substitution G A downstream_gene_variant ESAD-UK 14 24694131 24694131 single base substitution G A intron_variant ESAD-UK 14 24694268 24694268 single base substitution G A downstream_gene_variant ESAD-UK 14 24694268 24694268 single base substitution G A intron_variant ESAD-UK 14 24696672 24696672 single base substitution C T exon_variant ESAD-UK 14 24696672 24696672 single base substitution C T intron_variant ESAD-UK 14 24700504 24700504 single base substitution T G intron_variant ESAD-UK 14 24700838 24700838 single base substitution C T intron_variant ESAD-UK 14 24706623 24706623 single base substitution G A upstream_gene_variant ESCA-CN 14 24686388 24686388 single base substitution C G 3_prime_UTR_variant ESCA-CN 14 24686388 24686388 single base substitution C G downstream_gene_variant ESCA-CN 14 24686388 24686388 single base substitution C G exon_variant ESCA-CN 14 24686388 24686388 single base substitution C G missense_variant G64A 191G>C GBM-US 14 24683351 24683351 single base substitution G A downstream_gene_variant LAML-KR 14 24683125 24683125 single base substitution A G downstream_gene_variant LAML-KR 14 24695231 24695231 single base substitution T G downstream_gene_variant LAML-KR 14 24695231 24695231 single base substitution T G intron_variant LAML-KR 14 24705295 24705295 single base substitution T C upstream_gene_variant LICA-FR 14 24695652 24695653 deletion of <=200bp AA - downstream_gene_variant LICA-FR 14 24695652 24695653 deletion of <=200bp AA - intron_variant LINC-JP 14 24687512 24687512 single base substitution A G intron_variant LINC-JP 14 24702766 24702766 insertion of <=200bp - A upstream_gene_variant LINC-JP 14 24703372 24703372 single base substitution C G upstream_gene_variant LINC-JP 14 24703773 24703773 single base substitution A G upstream_gene_variant LINC-JP 14 24704355 24704355 single base substitution A C upstream_gene_variant LIRI-JP 14 24681294 24681294 single base substitution A G downstream_gene_variant LIRI-JP 14 24684073 24684073 single base substitution C G downstream_gene_variant LIRI-JP 14 24685213 24685213 single base substitution T C downstream_gene_variant LIRI-JP 14 24687873 24687873 single base substitution C A exon_variant LIRI-JP 14 24687873 24687873 single base substitution C A intron_variant LIRI-JP 14 24688990 24688990 single base substitution G A intron_variant LIRI-JP 14 24688990 24688990 single base substitution G A upstream_gene_variant LIRI-JP 14 24692189 24692189 single base substitution G T downstream_gene_variant LIRI-JP 14 24692189 24692189 single base substitution G T intron_variant LIRI-JP 14 24692189 24692189 single base substitution G T upstream_gene_variant LIRI-JP 14 24696078 24696078 single base substitution A C exon_variant LIRI-JP 14 24696078 24696078 single base substitution A C intron_variant LIRI-JP 14 24699008 24699008 single base substitution G A intron_variant LIRI-JP 14 24699149 24699149 single base substitution C T intron_variant LIRI-JP 14 24701871 24701871 single base substitution A T upstream_gene_variant LIRI-JP 14 24702401 24702401 single base substitution T G upstream_gene_variant LIRI-JP 14 24705931 24705931 single base substitution A G upstream_gene_variant LIRI-JP 14 24706001 24706001 single base substitution G A upstream_gene_variant LUSC-KR 14 24687771 24687771 single base substitution G A exon_variant LUSC-KR 14 24687771 24687771 single base substitution G A intron_variant LUSC-KR 14 24688023 24688023 single base substitution G A intron_variant LUSC-KR 14 24688023 24688023 single base substitution G A upstream_gene_variant LUSC-KR 14 24689246 24689246 single base substitution G A intron_variant LUSC-KR 14 24689246 24689246 single base substitution G A upstream_gene_variant LUSC-KR 14 24692945 24692945 single base substitution A T downstream_gene_variant LUSC-KR 14 24692945 24692945 single base substitution A T intron_variant LUSC-KR 14 24697059 24697059 single base substitution G T exon_variant LUSC-KR 14 24697059 24697059 single base substitution G T intron_variant LUSC-KR 14 24700194 24700194 single base substitution C T intron_variant LUSC-KR 14 24700712 24700712 single base substitution T G intron_variant LUSC-US 14 24684816 24684816 single base substitution C A downstream_gene_variant MALY-DE 14 24681701 24681701 single base substitution T A downstream_gene_variant MALY-DE 14 24683695 24683695 single base substitution T C downstream_gene_variant MALY-DE 14 24684755 24684755 single base substitution T C downstream_gene_variant MALY-DE 14 24692872 24692872 single base substitution A C downstream_gene_variant MALY-DE 14 24692872 24692872 single base substitution A C intron_variant MALY-DE 14 24692872 24692872 single base substitution A C upstream_gene_variant MALY-DE 14 24696288 24696288 single base substitution A G exon_variant MALY-DE 14 24696288 24696288 single base substitution A G intron_variant MALY-DE 14 24696311 24696311 single base substitution T G exon_variant MALY-DE 14 24696311 24696311 single base substitution T G intron_variant MELA-AU 14 24682560 24682560 single base substitution C T downstream_gene_variant MELA-AU 14 24682731 24682731 single base substitution G A downstream_gene_variant MELA-AU 14 24683082 24683082 single base substitution C T downstream_gene_variant MELA-AU 14 24684988 24684989 multiple base substitution (>=2bp and <=200bp) GG TA downstream_gene_variant MELA-AU 14 24685776 24685776 single base substitution G A downstream_gene_variant MELA-AU 14 24686176 24686176 single base substitution G A 3_prime_UTR_variant MELA-AU 14 24686176 24686176 single base substitution G A downstream_gene_variant MELA-AU 14 24686176 24686176 single base substitution G A exon_variant MELA-AU 14 24686435 24686435 single base substitution G A downstream_gene_variant MELA-AU 14 24686435 24686435 single base substitution G A intron_variant MELA-AU 14 24687380 24687380 single base substitution G A exon_variant MELA-AU 14 24687380 24687380 single base substitution G A intron_variant MELA-AU 14 24687380 24687380 single base substitution G A synonymous_variant I36I 108C>T MELA-AU 14 24687477 24687477 single base substitution G A intron_variant MELA-AU 14 24687600 24687601 multiple base substitution (>=2bp and <=200bp) GG AA exon_variant MELA-AU 14 24687600 24687601 multiple base substitution (>=2bp and <=200bp) GG AA intron_variant MELA-AU 14 24687600 24687601 multiple base substitution (>=2bp and <=200bp) GG AA missense_variant P19F 55CC>TT MELA-AU 14 24687975 24687976 multiple base substitution (>=2bp and <=200bp) GG AA intron_variant MELA-AU 14 24687975 24687976 multiple base substitution (>=2bp and <=200bp) GG AA upstream_gene_variant MELA-AU 14 24688231 24688231 single base substitution G A intron_variant MELA-AU 14 24688231 24688231 single base substitution G A upstream_gene_variant MELA-AU 14 24688374 24688374 single base substitution A G intron_variant MELA-AU 14 24688374 24688374 single base substitution A G upstream_gene_variant MELA-AU 14 24688400 24688400 single base substitution G A intron_variant MELA-AU 14 24688400 24688400 single base substitution G A upstream_gene_variant MELA-AU 14 24689597 24689597 single base substitution G A intron_variant MELA-AU 14 24689597 24689597 single base substitution G A upstream_gene_variant MELA-AU 14 24690014 24690014 single base substitution G A intron_variant MELA-AU 14 24690014 24690014 single base substitution G A upstream_gene_variant MELA-AU 14 24690128 24690128 single base substitution G A intron_variant MELA-AU 14 24690128 24690128 single base substitution G A upstream_gene_variant MELA-AU 14 24690311 24690311 single base substitution G A intron_variant MELA-AU 14 24690311 24690311 single base substitution G A upstream_gene_variant MELA-AU 14 24690628 24690628 single base substitution G A intron_variant MELA-AU 14 24690628 24690628 single base substitution G A upstream_gene_variant MELA-AU 14 24690835 24690835 single base substitution C T downstream_gene_variant MELA-AU 14 24690835 24690835 single base substitution C T intron_variant MELA-AU 14 24690835 24690835 single base substitution C T upstream_gene_variant MELA-AU 14 24690965 24690965 single base substitution G A downstream_gene_variant MELA-AU 14 24690965 24690965 single base substitution G A intron_variant MELA-AU 14 24690965 24690965 single base substitution G A upstream_gene_variant MELA-AU 14 24691115 24691115 single base substitution G A downstream_gene_variant MELA-AU 14 24691115 24691115 single base substitution G A intron_variant MELA-AU 14 24691115 24691115 single base substitution G A upstream_gene_variant MELA-AU 14 24692476 24692476 single base substitution G A downstream_gene_variant MELA-AU 14 24692476 24692476 single base substitution G A intron_variant MELA-AU 14 24692476 24692476 single base substitution G A upstream_gene_variant MELA-AU 14 24692588 24692588 single base substitution G A downstream_gene_variant MELA-AU 14 24692588 24692588 single base substitution G A intron_variant MELA-AU 14 24692588 24692588 single base substitution G A upstream_gene_variant MELA-AU 14 24692590 24692590 single base substitution G A downstream_gene_variant MELA-AU 14 24692590 24692590 single base substitution G A intron_variant MELA-AU 14 24692590 24692590 single base substitution G A upstream_gene_variant MELA-AU 14 24692746 24692746 single base substitution T C downstream_gene_variant MELA-AU 14 24692746 24692746 single base substitution T C intron_variant MELA-AU 14 24692746 24692746 single base substitution T C upstream_gene_variant MELA-AU 14 24692984 24692984 single base substitution C T downstream_gene_variant MELA-AU 14 24692984 24692984 single base substitution C T intron_variant MELA-AU 14 24693182 24693182 single base substitution G A downstream_gene_variant MELA-AU 14 24693182 24693182 single base substitution G A intron_variant MELA-AU 14 24693761 24693761 single base substitution C T downstream_gene_variant MELA-AU 14 24693761 24693761 single base substitution C T intron_variant MELA-AU 14 24694714 24694714 single base substitution G A downstream_gene_variant MELA-AU 14 24694714 24694714 single base substitution G A intron_variant MELA-AU 14 24695161 24695161 single base substitution C A downstream_gene_variant MELA-AU 14 24695161 24695161 single base substitution C A intron_variant MELA-AU 14 24695163 24695163 single base substitution T A downstream_gene_variant MELA-AU 14 24695163 24695163 single base substitution T A intron_variant MELA-AU 14 24696116 24696116 single base substitution A C exon_variant MELA-AU 14 24696116 24696116 single base substitution A C intron_variant MELA-AU 14 24696156 24696156 single base substitution G A exon_variant MELA-AU 14 24696156 24696156 single base substitution G A intron_variant MELA-AU 14 24696529 24696529 single base substitution G A exon_variant MELA-AU 14 24696529 24696529 single base substitution G A intron_variant MELA-AU 14 24696630 24696630 single base substitution G A exon_variant MELA-AU 14 24696630 24696630 single base substitution G A intron_variant MELA-AU 14 24697993 24697993 single base substitution T C intron_variant MELA-AU 14 24698860 24698860 single base substitution G A intron_variant MELA-AU 14 24698871 24698871 single base substitution A G intron_variant MELA-AU 14 24699986 24699986 single base substitution G A intron_variant MELA-AU 14 24701578 24701578 single base substitution C T 5_prime_UTR_variant MELA-AU 14 24701578 24701578 single base substitution C T upstream_gene_variant MELA-AU 14 24704419 24704419 single base substitution G A upstream_gene_variant MELA-AU 14 24706169 24706170 multiple base substitution (>=2bp and <=200bp) CC TT upstream_gene_variant OV-AU 14 24681576 24681576 single base substitution C G downstream_gene_variant OV-AU 14 24684921 24684921 single base substitution G T downstream_gene_variant OV-AU 14 24685537 24685537 single base substitution T C downstream_gene_variant OV-AU 14 24694264 24694264 single base substitution C G downstream_gene_variant OV-AU 14 24694264 24694264 single base substitution C G intron_variant OV-AU 14 24695264 24695264 single base substitution A C downstream_gene_variant OV-AU 14 24695264 24695264 single base substitution A C intron_variant OV-AU 14 24703022 24703022 single base substitution T G upstream_gene_variant PACA-AU 14 24681817 24681817 single base substitution T C downstream_gene_variant PACA-AU 14 24684475 24684475 single base substitution A G downstream_gene_variant PACA-AU 14 24694227 24694227 single base substitution T C downstream_gene_variant PACA-AU 14 24694227 24694227 single base substitution T C intron_variant PACA-AU 14 24696698 24696698 single base substitution G A exon_variant PACA-AU 14 24696698 24696698 single base substitution G A intron_variant PACA-AU 14 24699184 24699184 single base substitution G A intron_variant PACA-AU 14 24699522 24699522 single base substitution C T intron_variant PACA-CA 14 24688410 24688410 single base substitution G A intron_variant PACA-CA 14 24688410 24688410 single base substitution G A upstream_gene_variant PACA-CA 14 24692749 24692749 single base substitution A T downstream_gene_variant PACA-CA 14 24692749 24692749 single base substitution A T intron_variant PACA-CA 14 24692749 24692749 single base substitution A T upstream_gene_variant PACA-CA 14 24704861 24704861 single base substitution C G upstream_gene_variant PACA-CA 14 24704864 24704864 single base substitution A C upstream_gene_variant PACA-CA 14 24704937 24704937 single base substitution C G upstream_gene_variant PACA-CA 14 24705553 24705553 single base substitution T C upstream_gene_variant PAEN-AU 14 24695637 24695637 single base substitution G C downstream_gene_variant PAEN-AU 14 24695637 24695637 single base substitution G C intron_variant PBCA-DE 14 24687403 24687403 single base substitution G A exon_variant PBCA-DE 14 24687403 24687403 single base substitution G A intron_variant PBCA-DE 14 24687403 24687403 single base substitution G A missense_variant R29C 85C>T PBCA-DE 14 24696711 24696711 single base substitution G C exon_variant PBCA-DE 14 24696711 24696711 single base substitution G C intron_variant PRAD-CA 14 24693643 24693643 single base substitution C G downstream_gene_variant PRAD-CA 14 24693643 24693643 single base substitution C G intron_variant PRAD-UK 14 24686652 24686652 single base substitution C T downstream_gene_variant PRAD-UK 14 24686652 24686652 single base substitution C T intron_variant PRAD-US 14 24682652 24682652 single base substitution C G downstream_gene_variant PRAD-US 14 24702732 24702732 single base substitution C A upstream_gene_variant READ-US 14 24683287 24683287 single base substitution C T downstream_gene_variant READ-US 14 24683741 24683741 single base substitution G T downstream_gene_variant READ-US 14 24706350 24706350 single base substitution T G upstream_gene_variant RECA-EU 14 24682705 24682705 single base substitution T A downstream_gene_variant RECA-EU 14 24685655 24685655 single base substitution G A downstream_gene_variant RECA-EU 14 24698109 24698109 single base substitution A T intron_variant SKCA-BR 14 24681486 24681486 single base substitution A C downstream_gene_variant SKCA-BR 14 24681755 24681755 single base substitution A C downstream_gene_variant SKCA-BR 14 24682636 24682636 single base substitution G C downstream_gene_variant SKCA-BR 14 24684638 24684638 single base substitution G A downstream_gene_variant SKCA-BR 14 24686436 24686436 single base substitution G A downstream_gene_variant SKCA-BR 14 24686436 24686436 single base substitution G A intron_variant SKCA-BR 14 24687457 24687457 single base substitution G A intron_variant SKCA-BR 14 24692932 24692932 insertion of <=200bp - GA downstream_gene_variant SKCA-BR 14 24692932 24692932 insertion of <=200bp - GA intron_variant SKCA-BR 14 24692932 24692932 insertion of <=200bp - GA upstream_gene_variant SKCA-BR 14 24693513 24693513 single base substitution A C downstream_gene_variant SKCA-BR 14 24693513 24693513 single base substitution A C intron_variant SKCA-BR 14 24694377 24694377 insertion of <=200bp - CA downstream_gene_variant SKCA-BR 14 24694377 24694377 insertion of <=200bp - CA intron_variant SKCA-BR 14 24702453 24702453 single base substitution A G upstream_gene_variant SKCM-US 14 24682669 24682669 single base substitution C A downstream_gene_variant SKCM-US 14 24682688 24682688 single base substitution G A downstream_gene_variant SKCM-US 14 24684863 24684863 single base substitution C T downstream_gene_variant SKCM-US 14 24701578 24701578 single base substitution C T 5_prime_UTR_variant SKCM-US 14 24701578 24701578 single base substitution C T upstream_gene_variant SKCM-US 14 24706339 24706339 single base substitution C T upstream_gene_variant STAD-US 14 24705334 24705334 single base substitution G A upstream_gene_variant UCEC-US 14 24683240 24683240 single base substitution A C downstream_gene_variant UCEC-US 14 24683257 24683257 single base substitution G A downstream_gene_variant UCEC-US 14 24683309 24683309 single base substitution C T downstream_gene_variant UCEC-US 14 24686360 24686360 single base substitution C G 3_prime_UTR_variant UCEC-US 14 24686360 24686360 single base substitution C G downstream_gene_variant UCEC-US 14 24686360 24686360 single base substitution C G exon_variant UCEC-US 14 24686360 24686360 single base substitution C G synonymous_variant L73L 219G>C UCEC-US 14 24702774 24702774 single base substitution C T upstream_gene_variant UCEC-US 14 24704989 24704989 single base substitution G C upstream_gene_variant UCEC-US 14 24706542 24706542 single base substitution A T upstream_gene_variant

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand TCGA-AG-3892-01 COSM257509 c.74G>A p.R25Q Substitution - Missense 14:24218208-24218208 - PAPNNX COSM5005035 c.86G>A p.R29H Substitution - Missense 14:24218196-24218196 - MD-319 COSM302738 c.85C>T p.R29C Substitution - Missense 14:24218197-24218197 - 61 COSM5005035 c.86G>A p.R29H Substitution - Missense 14:24218196-24218196 - 229 COSM2032922 c.131T>C p.I44T Substitution - Missense 14:24218151-24218151 - HCT116 COSM2032922 c.131T>C p.I44T Substitution - Missense 14:24218151-24218151 - LC_S45 COSM1188784 c.222A>T p.R74S Substitution - Missense 14:24217151-24217151 - ESCC-128T COSM3936489 c.191G>C p.G64A Substitution - Missense 14:24217182-24217182 - TCGA-H4-A2HQ-01 COSM1300538 c.132C>T p.I44I Substitution - coding silent 14:24218150-24218150 - TCGA-A2-A0YK-01 COSM432947 c.78C>G p.I26M Substitution - Missense 14:24218204-24218204 - TCGA-B5-A11R-01 COSM954966 c.219G>C p.L73L Substitution - coding silent 14:24217154-24217154 - ICGC_MB126 COSM302738 c.85C>T p.R29C Substitution - Missense 14:24218197-24218197 -

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.531042;Hs.531053;Hs.531064 14q12 603171

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer C A Nonsense p.G76* c.226G>T 14 24686353 STAD C T 5-UTRSNV . c.1-105G>A 14 24701578 CM C T Missense p.R25Q c.74G>A 14 24687414 LUAD C T Missense p.V23M c.67G>A 14 24687421 LUAD G A Missense p.P37S c.109C>T 14 24687379 CM G A Missense p.R29C c.85C>T 14 24687403 MB G C Missense p.I26M c.78C>G 14 24687410 BRCA G C Missense p.T55R c.164C>G 14 24686415 HNSC