Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 1 10190884 rs2295294 A T rs2295294 0.0000086 Lumbar spine bone mineral density HPOID:0004348 DOID:0080011 A intron GWASdb_trait 1 10190884 rs2295294 A T rs2295294 0.000377 Lumbar spine bone mineral density (males) HPOID:0004348 DOID:0080011 A intron GWASdb_trait 1 10231463 rs12092513 C T rs12092513 1.18E-05 Coronary heart disease HPOID:0001677 DOID:3393 T intron GWASdb_trait 1 10232534 rs11121524 C G rs11121524 5.45E-04 Alcohol dependence HPOID:0000707 DOID:0050741 G intron GWASdb_trait 1 10235946 rs2180184 T C rs2180184 5.36E-04 Self-reported allergy HPOID:0002715 DOID:0060056 A intron GWASdb_trait 1 10236039 rs6541080 G A rs6541080 2.50E-05 Urinary metabolites HPOID:0000079 DOID:557 A intron GWASdb_trait 1 10236402 rs7418410 C T rs7418410 4.34E-04 Alzheimer's disease (late onset) HPOID:0002511 DOID:10652 T intron GWASdb_trait 1 10236402 rs7418410 C T rs7418410 1.10E-05 Urinary metabolites HPOID:0000079 DOID:557 T intron GWASdb_trait

Disease associated variation - GWAS Central Study Name Source Marker Accession Chromosome Marker Start Marker Stop Alleles Gene Section P-value -log(p-value) GWAS of prostate cancer rs11121515 1 10125765 10125765 intronic 0.901547 0.0450116274456514 GWAS of prostate cancer rs12076922 1 10165301 10165301 intronic 0.669078 0.17452324995270302 GWAS of prostate cancer rs9430244 1 10155283 10155283 intronic 0.59212 0.22759026953285402 GWAS of prostate cancer rs7528979 1 10093457 10093457 UTR5 0.454266 0.342689767180442 GWAS of prostate cancer rs6541080 1 10236039 10236039 intronic 0.379352 0.420957621928966 GWAS of prostate cancer rs12092513 1 10231463 10231463 intronic 0.311193 0.506970180626966 GWAS of prostate cancer rs12070814 1 10200574 10200574 intronic 0.283678 0.54717434361578 GWAS of prostate cancer rs6671289 1 10195940 10195940 intronic 0.180896 0.742571036219975

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000130939.18 UBE4B 613565