PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus UBE4B UBL7 22863883,26186194,22939629 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B SARNP 22939629 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G NDUFA2 UBE4B 22939629 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBA6 UBE4B 22939629 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBE4B PDE3A 22863883 biogrid exp G GP G G GP GP G GP GP G GP G GP G G GP GP G GP G G G GP G GP GP G G G UBE4B MDM2 24587254,21317885 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B MRPL53 22939629 biogrid exp P P P P P P P P P P P P P P P P P P P UBE4B UBE2D3 15466860,20017557,20696396,23550736 biogrid,dip exp GP G G G GP GP G G GP G GP G GP GP G G GP GP GP G GP GP G G G GP GP GP G UBE4B TTK 22045814 biogrid exp P P G GP P P GP P P P GP P P P P P P GP P GP GP SCO2 UBE4B 22939629 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP G GP GP GP GP G UBE4B XPC 19889839 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B CASP6 11802788 hprd exp GP G G GP G G GP GP G G GP G GP GP GP P GP GP GP G GP G UBE4B SRPRB 22939629 biogrid exp GP GP G G GP G G GP GP G GP G GP GP G GP G GP GP G GP G GP G GP G GP GP G UBE4B SF3B4 22939629 biogrid exp G GP G G GP GP G GP GP G GP G GP G G G GP G GP G GP G G G G G GP GP G UBE4B VAV2 18654987 biogrid,intact exp GP GP G G GP GP G G GP G GP G GP G G GP GP GP GP G GP GP GP GP GP GP GP G SSSCA1 UBE4B 22939629 biogrid exp GP P G GP P G P GP G G P G P P GP G GP G G GP GP G UBE4B STAM 24344129 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP G GP GP G UBE4B USP9X 22939629 biogrid exp GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B TP63 18418053 biogrid exp GP G G G G G G G G G G G G G G G G G G GP GP G G G G G UBE4B THY1 22939629 biogrid exp G G G G G GP G G G G GP G G G G G GP G G G G G G G G G G G G UBE4B PSMB1 22939629 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B ESR1 25640309 biogrid,intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE4B IGBP1 22939629 biogrid exp GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G VPS4B UBE4B 22939629 biogrid exp GP G G G GP GP G G GP G GP G G G G GP GP G GP G GP GP GP G GP GP GP GP G UBE4B TRIP6 22939629 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B EGFR 24189400 intact exp GP GP G GP G G GP G GP G G G G GP GP G G G GP GP G G GP G GP GP G UBE4B PCID2 26344197 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE4B UBE2L3 22939629 biogrid exp GP G G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G UBE4B CASP7 11802788 hprd,bci exp GP GP G G G GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP G GP GP G TP73 UBE4B 16170377 biogrid exp G G G G G UBE4B CDKN2A 17955473 biogrid,intact exp G GP G G GP GP G G G G G G GP GP G G GP G GP G GP G G G G GP GP G G UBE4B ELAVL1 19322201 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP G GP GP G UBE4B FEZ1 15466860 biogrid exp GP GP G G GP GP G GP GP G GP G GP G G GP GP G GP G GP GP GP G GP GP GP GP G UBE4B PPIF 22939629 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE4B TTC9C 22939629 biogrid exp GP GP G G GP GP G GP GP G GP G GP G G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B HDLBP 22939629 biogrid exp GP GP G G GP GP G GP GP G GP G G GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE2C UBE4B 22939629 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B NUSAP1 22863883 biogrid exp GP GP G GP G G G GP GP G G GP G GP G G GP G GP P GP G GP GP GP GP G UBE4B FBXW11 26091241,25332235 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE4B FOXK1 26344197 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B RBM12 22863883 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G HGS UBE4B 24344129 biogrid exp GP GP G G GP GP G GP GP G GP G GP G G GP GP GP GP G GP GP GP G GP G GP GP G UBE4B GZMB 11802788 innatedb,hprd,bci exp G G GP G G GP G G G GP G G UBE4B CDC27 22045814 biogrid exp GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B VPS35 22939629 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP G GP GP G UBXN7 UBE4B 22939629 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B NDUFA7 22939629 biogrid exp GP GP G G GP GP G GP GP G GP G G G G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B ZRANB2 22939629 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B UFM1 22939629 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B USP34 22939629 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP GP GP G GP GP GP GP G UBE4B VPS29 22939629 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B SBDS 22939629 biogrid exp P P P P P P P P P P P P P P P P P P P UBE4B NUDCD3 22863883 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G AHCYL1 UBE4B 22939629 biogrid exp GP GP G G G GP G G GP G GP G G G G G GP G GP G G G GP G G G GP G G UBE4B NTRK1 25921289 biogrid exp P P P G P P P P P P P P P P P P P UBE4B ZFYVE19 22939629 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B CBL 20696396 biogrid exp G GP G G GP GP G G GP G GP G GP GP G G GP GP G G G G G G G GP G GP G UBE4B STUB1 26344197 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G VPS26A UBE4B 22939629 biogrid exp GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B TTC4 26344197 biogrid exp GP GP G G GP GP G GP GP G GP G P GP G GP GP GP GP G P GP GP G GP GP GP GP UBE4B VPS36 22939629 biogrid exp G GP G G G GP G GP GP G GP G GP G G GP GP GP GP G GP GP GP G GP G GP GP G UBE4B BTRC 26091241 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP G GP GP G UBE4B DNAJC7 15189447 hprd exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B ATP6V1F 22939629 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G ZPR1 UBE4B 22939629 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B UBE2V1 22939629 biogrid exp UBE4B TP53 24587254,21317885 biogrid,bci exp G G G G G G G G G G G G G G G GP G G G G GP G G G GP G G GP G UBE4B SULT1A1 22939629 biogrid exp GP GP G G G GP G GP GP G GP G G G G GP GP GP GP G GP G GP G GP G GP GP G UBE4B UBE4B 20017557 biogrid exp, ortho GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B UBE2D2 21317885,20696396 biogrid,dip exp, ortho GP G G G GP GP G G GP G GP G GP GP G G GP GP GP G GP GP G G G GP GP GP G UBE4B UCHL3 22939629 biogrid exp, ortho GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP G GP GP GP GP G UBE4B ATXN3 14749733,16525503 biogrid,intact exp, ortho GP GP G G GP GP G GP GP G GP G GP GP G P GP GP P G GP GP GP G GP GP GP GP G UBE4B VCP 19175675,12504083,18022694,14749733,20414249,16525503,21282470, 25402006, 21836163 hprd,biogrid,mint,intact,bci exp, ortho, pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B TRIP12 18627766, 25402006 biogrid exp, pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP G GP GP G UBE4B RAD23A 18234089, 25402006 biogrid exp, pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B UBQLN1 26344197,22939629, 25402006 biogrid exp, pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B UBXN1 18775313, 25402006 biogrid,intact exp, pred GP GP G G G GP G G GP G GP G GP GP G GP GP GP GP G GP GP G G GP GP GP GP G UBE4B UBE2D1 22939629, 25402006 biogrid exp, pred GP G G G GP GP G G GP G GP G GP GP G G GP GP GP G GP GP G G G GP GP GP G UBE4B CASP3 11802788, 21836163 hprd,bci exp, pred GP G G G GP G G GP G G G GP GP G GP G G GP G GP G G G GP GP GP GP G UBE4B ITPR1 ortho G G G G G GP G GP G G GP GP GP G G GP G G G GP G G GP GP GP G UBE4B NF2 ortho GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B YOD1 ortho GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP P G GP GP GP G GP GP GP GP G UBE4B DNAJB1 ortho GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B ABCB10 ortho GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B GYG1 ortho G G G G G GP G G G G GP G G GP G G GP GP GP G G G G G G G G GP G DNAJA2 UBE4B ortho GP GP G G GP GP G GP GP G GP G G GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B TRUB2 ortho G GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP G GP GP G STK16 UBE4B ortho GP P G G GP GP G GP GP G GP G GP G G GP GP G GP G GP GP GP G GP G GP GP G UBE4B MAD2L1 ortho P G G P P GP P P GP G GP P G P P GP P GP GP GP GP UBE4B FZR1 ortho G GP G G G GP G GP GP G GP G GP G G GP GP G P G G GP G G GP G GP GP G UBE4B HSPA9 ortho GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G EED UBE4B ortho GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP G GP G GP GP GP GP G UBE4B SUPT6H ortho GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B HSPA4 25402006 ortho, pred GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B UFD1L 25402006 ortho, pred G GP G G G GP G GP GP G GP G GP GP G GP GP G GP G GP GP G G GP G G GP G UBE4B RAD23B 25402006 ortho, pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B NSFL1C 25402006, 16082366 ortho, pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B NPLOC4 25402006, 16082366 ortho, pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B HRSP12 16082366 ortho, pred G GP G G G GP G G G G GP G G G G G GP G G G G G G G G G G GP G UBE4B TUBA1A 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B UBXN6 25402006 pred GP P G G GP GP G P P G GP P P G GP GP GP GP G P P GP G GP P GP GP G UBE4B RPS27A 16082366 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B CD2AP 25402006 pred GP GP G GP P G G GP GP G GP GP G GP GP G GP G GP GP GP G GP GP GP GP UBE4B DDB1 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B FAF1 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B ASPSCR1 25402006 pred GP GP G P GP G GP P G GP G GP GP G GP GP P GP G GP GP GP G GP G GP GP UBE4B ORM2 16082366 pred P P P P P P P P P P P UBE4B HSP90AB1 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B BRCA1 21836163 pred P P G GP P P P P P P GP P P P P P P P P P GP UBXN8 UBE4B 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE4B ARIH2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE4B Ubiquitin C variant 16082366 pred UBE4B SERPINB9 25402006 pred GP GP G G GP G G G G G GP G G GP G G G G G G G G G G G GP G GP G UBE4B BTBD2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE4B CASP9 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B ORM1 16082366 pred P P G GP P P P P G P P P GP G P UBE4B UBR2 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B CASP10 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP G G GP GP GP GP G UBE4B UBXN4 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B C16orf70 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP G GP G GP GP GP GP G UBE4B MAP3K3 25402006 pred G G G G GP GP G GP G G GP G GP GP G GP GP G G G GP G G G GP GP GP G G UBE4B APITD1 21836163 pred UBE4B UBE2D4 25402006 pred GP G G G GP GP G G GP G GP G GP GP G G GP GP GP G GP GP G G G GP GP GP G FCHSD2 UBE4B 25402006 pred GP GP G G GP GP G GP GP G GP G GP G G GP GP G GP G GP GP P G GP GP GP G G PARK2 UBE4B 25402006 pred P GP G P GP G GP GP G GP P G P GP GP P G P GP G GP P GP G UBE4B CUL2 25402006 pred GP GP G G G GP G G GP G GP G GP GP G G GP GP GP G GP GP GP G G G GP GP G UBE4B PRF1 25402006 pred G G G G G G G G G G G G GP G G G G G G G G G G G GP G G G UBE4B PTGES3 25402006 pred GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B PLAA 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B SVIP 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G P GP GP G GP GP GP GP G UBE4B VTN 25402006 pred P P P P P UBE4B VCPIP1 25402006 pred G G G G G G G GP GP G GP G G GP G GP G G P G GP G G G GP G GP G UBE4B PTPN3 25402006 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP G GP P GP GP G UBE4B UBR4 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP G GP G GP GP G UBE4B RNF19A 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B SRGN 25402006 pred G G G G GP GP G G G G G G GP GP G G GP G G G G G GP G G GP G G G UBE4B BID 25402006 pred G G G GP G G GP GP G G G GP GP G GP G G GP G G GP G G GP GP GP PJA2 UBE4B 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B PSMD7 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B SSB 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B SYVN1 25402006 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B RCHY1 25402006 pred G GP G G G GP G GP GP G GP G GP G G GP GP G GP G G G GP G GP G GP G G UBE4B AMFR 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B UBA52 16082366 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBR5 UBE4B 25402006 pred GP G G G G GP G G GP G GP G GP GP G G GP G G G GP G G G G G GP GP G DFFA UBE4B 25402006, 21836163 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B BARD1 21836163 pred P G GP P P GP P P GP G GP P G P P GP P G P GP GP GP G KIF1B UBE4B 21836163 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE4B CUL1 25402006 pred GP G G G G GP G GP GP G GP G GP G G GP GP GP GP G GP GP GP G GP GP GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants O95155 A0A024RDH2 x-ray crystallography 20696396 direct interaction X 2 O95155 A0A024RDH2 isothermal titration calorimetry 20696396 direct interaction X 2 O95155 A0A024RDH2 nuclear magnetic resonance 20696396 direct interaction X 2 O95155 P62837 isothermal titration calorimetry 20696396 direct interaction X 2 O95155 P62837 nuclear magnetic resonance 20696396 direct interaction X 2 O95155 anti tag coimmunoprecipitation 18775313 association C 13 O95155 anti tag coimmunoprecipitation 18775313 association C 18 O95155 anti tag coimmunoprecipitation 18775313 association C 5 O95155 pull down 17955473 association C 32 O95155 P52735 two hybrid 18654987 physical association X 2 O95155 G4XH65 two hybrid array 25640309 physical association X 2 O95155 anti tag coimmunoprecipitation 18775313 association C 6 O95155 competition binding 16525503 direct interaction C 3 O95155 tandem affinity purification 24189400 association C 31

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B UBE4B UBE2D1 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_239206 prey bait AHCYL1 UBE4B MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_238814 bait prey UBE4B TP63 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 18418053 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_209331|BIOGRID_209330 bait|prey prey|bait UBE4B GZMB MI:0492(in vitro) 11802788 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_27873 - - VPS26A UBE4B MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_237603 prey bait UBE4B UBXN1 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 18775313 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0914(association) (intact)|(intact)|(intact)|(biogrid)|(intact) UniProt_183208|UniProt_183214|UniProt_97410|BIOGRID_149392|UniProt_97404 prey|prey|prey|prey|prey bait|bait|bait|bait|bait UBE4B DNAJC7 MI:0493(in vivo) 15189447 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_31941 - - UBE4B FEZ1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 15466860 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid) BIOGRID_209078|BIOGRID_209077|BIOGRID_209080 bait|prey|bait prey|bait|prey UBE4B SULT1A1 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_240702 prey bait UBE4B TTK MI:0004(affinity chromatography technology) 22045814 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_244391 prey bait UBE4B TTC9C MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_239380 prey bait UBE4B VPS36 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_238617 bait prey UBE4B UBE2D2 MI:0114(x-ray crystallography)|MI:0004(affinity chromatography technology) 20696396,21317885 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_142464|BIOGRID_221548 bait|bait prey|prey UBE4B SRPRB MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_238089 prey bait UBE4B SBDS MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_240905 prey bait UBE4B PSMB1 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_239814 prey bait UBE4B CDC27 MI:0004(affinity chromatography technology) 22045814 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_244393 bait prey UBE4B PPIF MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_242731 prey bait UBE4B UBE2D3 MI:0004(affinity chromatography technology)|MI:0114(x-ray crystallography)|MI:0114(x-ray crystallography)|MI:0114(x-ray crystallography)|MI:0114(x-ray crystallography)|MI:0096(pull down) 15466860,20017557,20696396,23550736 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0914(association)|MI:0914(association)|MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_221527|BIOGRID_225935|BIOGRID_142465|BIOGRID_141383|BIOGRID_142463|BIOGRID_272616 bait|bait|bait|bait|bait|bait prey|prey|prey|prey|prey|prey UBE4B UFM1 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_240474 bait prey UBE4B UBA6 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_242425 prey bait VPS4B UBE4B MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_239809 prey bait UBE4B MRPL53 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_238940 prey bait UBE4B VPS35 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_239164 bait prey UBE4B UBL7 MI:0401(biochemical)|MI:0401(biochemical) 22863883,22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|MI:0403(colocalization) (biogrid)|(biogrid) BIOGRID_235744|BIOGRID_304771 bait|prey prey|bait UBE4B ZFYVE19 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_240269 bait prey SCO2 UBE4B MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_243359 bait prey UBE4B SARNP MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_243432 prey bait UBE4B VAV2 MI:0018(two hybrid)|MI:0018(two hybrid) 18654987 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_184856|UniProt_96811 prey|prey bait|bait UBE4B UBE2L3 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_243646 prey bait UBE4B UCHL3 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_241736 bait prey TP73 UBE4B MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 16170377 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_126421|BIOGRID_126422 prey|bait bait|prey UBE4B CBL MI:0114(x-ray crystallography) 20696396 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association) (biogrid) BIOGRID_142462 bait prey UBE4B VPS29 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_243766 bait prey UBE4B HDLBP MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_243096 bait prey UBE4B NRF1 MI:0428(imaging technique) 24250222 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_296784 prey bait UBE4B ATP6V1F MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_238538 bait prey UBE4B NUDCD3 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304767 prey bait UBE4B ZRANB2 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_240929 bait prey UBE4B NDUFA7 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_242195 prey bait UBE4B NUSAP1 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304768 prey bait UBE4B UBQLN1 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_239221 bait prey UBE4B CASP6 MI:0492(in vitro) 11802788 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_9268 - - UBE4B CASP7 MI:0492(in vitro) 11802788 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_9759 - - UBE4B MDM2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21317885,24587254 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_145881|BIOGRID_145883|BIOGRID_145877|BIOGRID_145876|BIOGRID_309368|BIOGRID_309367 prey|prey|prey|bait|prey|bait bait|bait|bait|prey|bait|prey UBE4B VCP MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0493(in vivo)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study) 12504083,14749733,16525503,18022694,19175675,20414249,21282470 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|-|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|MI:0471(mint)|MI:0468(hprd)|MI:0471(mint)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_200461|BIOGRID_200462|MINT_82102|HPRD_8273|MINT_49873|BIOGRID_193685|BIOGRID_132661|BIOGRID_132660|BIOGRID_136561|BIOGRID_148320 bait|prey|bait|-|bait|prey|prey|bait|bait|bait prey|bait|prey|-|prey|bait|bait|prey|prey|prey HGS UBE4B MI:0096(pull down) 24344129 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_309350 bait prey UBE4B SF3B4 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_242528 prey bait UBE4B USP34 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_236743 bait prey UBE4B ELAVL1 MI:0096(pull down) 19322201 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_187343 prey bait UBE4B TRIP6 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_241510 prey bait UBE4B UBC MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study) 21139048,21890473,21906983,21963094,21987572,22505724,23000965 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_170412|BIOGRID_166531|BIOGRID_267646|BIOGRID_223258|BIOGRID_179647|BIOGRID_175063|BIOGRID_163195 prey|prey|prey|prey|prey|prey|prey bait|bait|bait|bait|bait|bait|bait UBE4B IGBP1 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_239291 prey bait UBE4B RAD23A MI:0004(affinity chromatography technology) 18234089 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_208082 bait prey UBXN7 UBE4B MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_240250 prey bait UBE4B ATXN3 MI:0004(affinity chromatography technology)|MI:0096(pull down) 14749733,16525503 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(intact) BIOGRID_132662|UniProt_85210 prey|prey bait|null UBE4B CASP3 MI:0492(in vitro) 11802788 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_7425 - - UBE4B CDKN2A MI:0096(pull down)|MI:0004(affinity chromatography technology) 17955473 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_93315|BIOGRID_297198 prey|prey bait|bait UBE2C UBE4B MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_239440 bait prey SSSCA1 UBE4B MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_237801 bait prey UBE4B PDE3A MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304769 prey bait UBE4B STAM MI:0096(pull down) 24344129 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309351 prey bait UBE4B p53 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21317885,24587254 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_145882|BIOGRID_145885|BIOGRID_145879|BIOGRID_145878|BIOGRID_309366|BIOGRID_145880 prey|bait|prey|bait|prey|prey bait|prey|bait|prey|bait|bait UBE4B THY1 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_241940 prey bait UBE4B USP9X MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_239854 bait prey NDUFA2 UBE4B MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_236865 bait prey UBE4B UBE2V1 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_240322 prey bait UBE4B RBM12 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304770 prey bait UBE4B XPC MI:0004(affinity chromatography technology) 19889839 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_135603 bait prey ZNF259 UBE4B MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_238454 prey bait

PPI - HINT Gene A Gene B PMID Method Quality UBA6 UBE4B 22939629 0401 HT UBE2C UBE4B 22939629 0401 HT NDUFA2 UBE4B 22939629 0401 HT SCO2 UBE4B 22939629 0401 HT AHCYL1 UBE4B 22939629 0401 HT SSSCA1 UBE4B 22939629 0401 HT ZPR1 UBE4B 22939629 0401 HT VPS4B UBE4B 22939629 0401 HT VPS26A UBE4B 22939629 0401 HT UBXN7 UBE4B 22939629 0401 HT UBE4B NDUFA7 22939629 0401 HT UBE4B ZRANB2 22939629 0401 HT UBE4B TTC4 26344197 0401 HT UBE4B THY1 22939629 0401 HT UBE4B UCHL3 22939629 0401 HT UBE4B PSMB1 22939629 0401 HT UBE4B PPIF 22939629 0401 HT UBE4B SULT1A1 22939629 0401 HT UBE4B UBE2D1 22939629 0401 HT UBE4B UBE2D3 20696396,20696396,20017557,20696396,20696396,23550736,20017557,15466860 0114,0096,0096,0065,0077,0096,0114,0096 LC UBE4B UFM1 22939629 0401 HT UBE4B UBE2D2 20696396,21317885,20696396,20696396,25801170 0065,0096,0077,0096,0096 LC UBE4B UBE2L3 22939629 0401 HT UBE4B IGBP1 22939629 0401 HT UBE4B SARNP 22939629 0401 HT UBE4B FOXK1 26344197 0401 HT UBE4B HDLBP 22939629 0401 HT UBE4B MDM2 21317885,21317885,24587254,21317885 0004,0096,0004,0401 LC UBE4B UBE2V1 22939629 0401 HT UBE4B PDE3A 22863883 0401 HT UBE4B SF3B4 22939629 0401 HT UBE4B TRIP6 22939629 0401 HT UBE4B ATP6V1F 22939629 0401 HT UBE4B Q53GA5 26673821,26673821,24587254,21317885,21317885,21317885,21317885 0401,0004,0004,0004,0415,0401,0096 LC UBE4B PCID2 26344197 0401 HT UBE4B USP34 22939629 0401 HT UBE4B VPS36 22939629 0401 HT UBE4B NUDCD3 22863883 0401 HT UBE4B TTC9C 22939629 0401 HT UBE4B USP9X 22939629 0401 HT UBE4B MRPL53 22939629 0401 HT UBE4B ZFYVE19 22939629 0401 HT UBE4B VPS35 22939629 0401 HT UBE4B UBL7 22863883,26186194,22939629 0401,0004,0401 HT UBE4B NUSAP1 22863883 0401 HT UBE4B RBM12 22863883 0401 HT UBE4B VPS29 22939629 0401 HT UBE4B FBXW11 25332235,26091241 0004,0004 LC UBE4B UBQLN1 26344197,22939629 0401,0401 HT UBE4B STUB1 26344197 0401 HT UBE4B SBDS 22939629 0401 HT UBE4B SRPRB 22939629 0401 HT UBE4B HEL-S-70 14749733,26389662,14749733,19175675,21282470,20414249,18022694 0096,0004,0004,0004,0004,0004,0004 LC UBA6 UBE4B 22939629 0401 HT UBE2C UBE4B 22939629 0401 HT NDUFA2 UBE4B 22939629 0401 HT SCO2 UBE4B 22939629 0401 HT AHCYL1 UBE4B 22939629 0401 HT SSSCA1 UBE4B 22939629 0401 HT ZPR1 UBE4B 22939629 0401 HT VPS4B UBE4B 22939629 0401 HT VPS26A UBE4B 22939629 0401 HT UBXN7 UBE4B 22939629 0401 HT UBE4B NDUFA7 22939629 0401 HT UBE4B ZRANB2 22939629 0401 HT UBE4B TTC4 26344197 0401 HT UBE4B THY1 22939629 0401 HT UBE4B UCHL3 22939629 0401 HT UBE4B PSMB1 22939629 0401 HT UBE4B PPIF 22939629 0401 HT UBE4B SULT1A1 22939629 0401 HT UBE4B UBE2D1 22939629 0401 HT UBE4B UFM1 22939629 0401 HT UBE4B UBE2L3 22939629 0401 HT UBE4B IGBP1 22939629 0401 HT UBE4B SARNP 22939629 0401 HT UBE4B FOXK1 26344197 0401 HT UBE4B HDLBP 22939629 0401 HT UBE4B UBE2V1 22939629 0401 HT UBE4B PDE3A 22863883 0401 HT UBE4B SF3B4 22939629 0401 HT UBE4B TRIP6 22939629 0401 HT UBE4B ATP6V1F 22939629 0401 HT UBE4B PCID2 26344197 0401 HT UBE4B USP34 22939629 0401 HT UBE4B VPS36 22939629 0401 HT UBE4B NUDCD3 22863883 0401 HT UBE4B TTC9C 22939629 0401 HT UBE4B USP9X 22939629 0401 HT UBE4B MRPL53 22939629 0401 HT UBE4B ZFYVE19 22939629 0401 HT UBE4B VPS35 22939629 0401 HT UBE4B UBL7 22863883,26186194,22939629 0401,0004,0401 HT UBE4B NUSAP1 22863883 0401 HT UBE4B RBM12 22863883 0401 HT UBE4B VPS29 22939629 0401 HT UBE4B UBQLN1 26344197,22939629 0401,0401 HT UBE4B STUB1 26344197 0401 HT UBE4B SBDS 22939629 0401 HT UBE4B SRPRB 22939629 0401 HT UBE4B UBE2D3 20696396,20696396,20017557,20696396,20696396,23550736,20017557,15466860 0114,0096,0096,0065,0077,0096,0114,0096 LC UBE4B UBE2D2 20696396,21317885,20696396,20696396,25801170 0065,0096,0077,0096,0096 LC UBE4B MDM2 21317885,21317885,24587254,21317885 0004,0096,0004,0401 LC UBE4B Q53GA5 26673821,26673821,24587254,21317885,21317885,21317885,21317885 0401,0004,0004,0004,0415,0401,0096 LC UBE4B FBXW11 25332235,26091241 0004,0004 LC UBE4B HEL-S-70 14749733,26389662,14749733,19175675,21282470,20414249,18022694 0096,0004,0004,0004,0004,0004,0004 LC UBA6 UBE4B 22939629 0401 LC UBE2C UBE4B 22939629 0401 LC NDUFA2 UBE4B 22939629 0401 LC SCO2 UBE4B 22939629 0401 LC AHCYL1 UBE4B 22939629 0401 LC SSSCA1 UBE4B 22939629 0401 LC ZPR1 UBE4B 22939629 0401 LC VPS4B UBE4B 22939629 0401 LC VPS26A UBE4B 22939629 0401 LC UBXN7 UBE4B 22939629 0401 LC UBE4B UBE4B 20017557 0415 LC UBE4B NDUFA7 22939629 0401 LC UBE4B ZRANB2 22939629 0401 LC UBE4B TTC4 26344197 0401 LC UBE4B ESR1 25640309 0397 HT UBE4B THY1 22939629 0401 LC UBE4B GZMB 11802788 0435 LC UBE4B UCHL3 22939629 0401 LC UBE4B PSMB1 22939629 0401 LC UBE4B CBL 20696396 0114 LC UBE4B PPIF 22939629 0401 LC UBE4B SULT1A1 22939629 0401 LC UBE4B UBE2D1 22939629 0401 LC UBE4B VAV2 18654987 0018 HT UBE4B ATXN3 16525503 0405 LC UBE4B VCP 16525503 0405 LC UBE4B UBE2D3 20696396,20696396,20017557,20696396,20696396,20017557 0114,0096,0096,0065,0077,0114 LC UBE4B UFM1 22939629 0401 LC UBE4B UBE2D2 20696396,20696396,20696396 0065,0077,0096 LC UBE4B UBE2L3 22939629 0401 LC UBE4B IGBP1 22939629 0401 LC UBE4B SARNP 22939629 0401 LC UBE4B FOXK1 26344197 0401 LC UBE4B HDLBP 22939629 0401 LC UBE4B MDM2 21317885,21317885,21317885 0004,0096,0401 LC UBE4B UBE2V1 22939629 0401 LC UBE4B PDE3A 22863883 0401 LC UBE4B SF3B4 22939629 0401 LC UBE4B TRIP6 22939629 0401 LC UBE4B ATP6V1F 22939629 0401 LC UBE4B Q53GA5 26673821,26673821,21317885,21317885,21317885,21317885 0401,0004,0004,0415,0401,0096 LC UBE4B PCID2 26344197 0401 LC UBE4B USP34 22939629 0401 LC UBE4B VPS36 22939629 0401 LC UBE4B NUDCD3 22863883 0401 LC UBE4B TTC9C 22939629 0401 LC UBE4B USP9X 22939629 0401 LC UBE4B MRPL53 22939629 0401 LC UBE4B ZFYVE19 22939629 0401 LC UBE4B VPS35 22939629 0401 LC UBE4B UBL7 22863883,22939629 0401,0401 LC UBE4B DNAJC7 15189447 0018 LC UBE4B FEZ1 15466860,15466860 0415,0004 LC UBE4B NUSAP1 22863883 0401 LC UBE4B RBM12 22863883 0401 LC UBE4B VPS29 22939629 0401 LC UBE4B Q9UBT1 25640309 0018 HT UBE4B UBQLN1 26344197,22939629 0401,0401 LC UBE4B STUB1 26344197 0401 LC UBE4B SBDS 22939629 0401 LC UBE4B SRPRB 22939629 0401 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q5JVF3 O95155 PCID2 UBE4B 0.081 26344197 O95155 O14964 UBE4B HGS 0.309 24344129 O95155 O43678 UBE4B NDUFA2 0.081 22939629 O95155 O43819 UBE4B SCO2 0.081 22939629 O95155 O15350 UBE4B TP73 0.376 16170377 O95155 O43865 UBE4B AHCYL1 0.081 22939629 Q8N5M4 O95155 TTC9C UBE4B 0.081 22939629 Q8N726 O95155 CDKN2A UBE4B 0.183 17955473 O95155 O60232 UBE4B SSSCA1 0.081 22939629 Q9NTZ6 O95155 RBM12 UBE4B 0.081 22863883 Q9H3D4 O95155 TP63 UBE4B 0.376 18418053 Q8IVD9 O95155 NUDCD3 UBE4B 0.081 22863883 Q9Y5M8 O95155 SRPRB UBE4B 0.081 22939629 Q9Y3A5 O95155 SBDS UBE4B 0.081 22939629 Q9Y297 O95155 BTRC UBE4B 0.21 26091241 O95155 O35987 UBE4B NSFL1C 0.126 18775313 Q00341 O95155 HDLBP UBE4B 0.081 22939629 O95155 O75351 UBE4B VPS4B 0.081 22939629 O95218 O95155 ZRANB2 UBE4B 0.081 22939629 O95155 O75312 UBE4B ZPR1 0.081 22939629 O95155 O75436 UBE4B VPS26A 0.081 22939629 O95155 O95155 UBE4B UBE4B 0.332 20017557 O95155 O94888 UBE4B UBXN7 0.081 22939629 P30260 O95155 CDC27 UBE4B 0.21 22045814 P03372 O95155 ESR1 UBE4B 0.286 25640309 P85037 O95155 FOXK1 UBE4B 0.081 26344197 P22681 O95155 CBL UBE4B 0.309 20696396 P15374 O95155 UCHL3 UBE4B 0.081 22939629 P54725 O95155 RAD23A UBE4B 0.309 18234089 P61960 O95155 UFM1 UBE4B 0.081 22939629 Q01831 O95155 XPC UBE4B 0.21 19889839 Q14669 O95155 TRIP12 UBE4B 0.309 18627766 Q86VN1 O95155 VPS36 UBE4B 0.081 22939629 Q16864 O95155 ATP6V1F UBE4B 0.081 22939629 Q70CQ2 O95155 USP34 UBE4B 0.081 22939629 Q96QK1 O95155 VPS35 UBE4B 0.081 22939629 Q93008 O95155 USP9X UBE4B 0.081 22939629 Q96K21 O95155 ZFYVE19 UBE4B 0.081 22939629 Q9UBQ0 O95155 VPS29 UBE4B 0.081 22939629 P00533 O95155 EGFR UBE4B 0.126 24189400 P04216 O95155 THY1 UBE4B 0.081 22939629 P04629 O95155 NTRK1 UBE4B 0.126 25921289 O95801 O95155 TTC4 UBE4B 0.081 26344197 Q9UKB1 O95155 FBXW11 UBE4B 0.309 26091241,25332235 Q96S82 O95155 UBL7 UBE4B 0.196 22863883,26186194 Q04323 O95155 UBXN1 UBE4B 0.236 18775313 P42771 O95155 CDKN2A UBE4B 0.286 17955473 Q00987 O95155 MDM2 UBE4B 0.765 21317885,24587254 Q9UMX0 O95155 UBQLN1 UBE4B 0.155 22939629,26344197 P54252 O95155 ATXN3 UBE4B 0.523 14749733,16525503 O95155 A2AUM9 UBE4B CEP152 0.236 26496610 P04637 O95155 TP53 UBE4B 0.888 21317885,24587254,26673821 P62837 O95155 UBE2D2 UBE4B 0.671 20696396,25801170,21317885 P55072 O95155 VCP UBE4B 0.853 19175675,18022694,20414249,14749733,21282470,26389662 P61077 O95155 UBE2D3 UBE4B 0.843 23550736,20696396,20017557,15466860 P30405 O95155 PPIF UBE4B 0.081 22939629 Q92783 O95155 STAM UBE4B 0.21 24344129 Q96EL3 O95155 MRPL53 UBE4B 0.081 22939629 Q9BXS6 O95155 NUSAP1 UBE4B 0.081 22863883 Q99689 O95155 FEZ1 UBE4B 0.569 15466860 P33981 O95155 TTK UBE4B 0.21 22045814 P78318 O95155 IGBP1 UBE4B 0.081 22939629 P82979 O95155 SARNP UBE4B 0.081 22939629 Q14432 O95155 PDE3A UBE4B 0.081 22863883 P50225 O95155 SULT1A1 UBE4B 0.081 22939629 Q15427 O95155 SF3B4 UBE4B 0.081 Q13404 O95155 UBE2V1 UBE4B 0.081 22939629 P51668 O95155 UBE2D1 UBE4B 0.081 22939629 Q15654 O95155 TRIP6 UBE4B 0.081 22939629 Q15717 O95155 ELAVL1 UBE4B 0.126 19322201 P20618 O95155 PSMB1 UBE4B 0.081 22939629 P68036 O95155 UBE2L3 UBE4B 0.081 22939629 O95155 A0AVT1 UBE4B UBA6 0.081 22939629 O95155 O00762 UBE4B UBE2C 0.081 22939629 P52735 O95155 VAV2 UBE4B 0.332 18654987

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 HGS UBE4B MI:0045 experimental interaction detection MI:0461 interaction database PFDN6 UBE4B MI:0362 inference MI:0461 interaction database TP73 UBE4B MI:0045 experimental interaction detection MI:0461 interaction database DNAJA2 UBE4B MI:0362 inference MI:0461 interaction database EED UBE4B MI:0362 inference MI:0461 interaction database STK16 UBE4B MI:0362 inference MI:0461 interaction database DNAJB5 UBE4B MI:0362 inference MI:0461 interaction database CEP152 UBE4B MI:0362 inference MI:0461 interaction database UBE4B HSPA4L MI:0362 inference MI:0461 interaction database UBE4B TRUB2 MI:0362 inference MI:0461 interaction database UBE4B EGFR MI:0045 experimental interaction detection MI:0461 interaction database UBE4B ESR1 MI:0045 experimental interaction detection MI:0461 interaction database UBE4B NTRK1 MI:0045 experimental interaction detection MI:0461 interaction database UBE4B TP53 MI:0045 experimental interaction detection MI:0461 interaction database UBE4B HSP90AA1 MI:0362 inference MI:0461 interaction database UBE4B ERCC1 MI:0362 inference MI:0461 interaction database UBE4B HSP90AB1 MI:0362 inference MI:0461 interaction database UBE4B UBB MI:0362 inference MI:0461 interaction database UBE4B UBC MI:0045 experimental interaction detection MI:0461 interaction database UBE4B HSPA1A MI:0362 inference MI:0461 interaction database UBE4B HSPA1B MI:0362 inference MI:0461 interaction database UBE4B HSPA8 MI:0362 inference MI:0461 interaction database UBE4B HSPA6 MI:0362 inference MI:0461 interaction database UBE4B CBL MI:0045 experimental interaction detection MI:0461 interaction database UBE4B DNAJB1 MI:0362 inference MI:0461 interaction database UBE4B CDC27 MI:0045 experimental interaction detection MI:0461 interaction database UBE4B MAT2A MI:0362 inference MI:0461 interaction database UBE4B DNAJA1 MI:0362 inference MI:0461 interaction database UBE4B TTK MI:0045 experimental interaction detection MI:0461 interaction database UBE4B HSPA1L MI:0362 inference MI:0461 interaction database UBE4B HSPA4 MI:0362 inference MI:0461 interaction database UBE4B NF2 MI:0362 inference MI:0461 interaction database UBE4B HSPA9 MI:0362 inference MI:0461 interaction database UBE4B CDKN2A MI:0045 experimental interaction detection MI:0461 interaction database UBE4B NEDD4 MI:0362 inference MI:0461 interaction database UBE4B CSNK1D MI:0362 inference MI:0461 interaction database UBE4B NOVA1 MI:0362 inference MI:0461 interaction database UBE4B UBE2D1 MI:0362 inference MI:0461 interaction database UBE4B UBE2E1 MI:0362 inference MI:0461 interaction database UBE4B VAV2 MI:0045 experimental interaction detection MI:0461 interaction database UBE4B HRSP12 MI:0362 inference MI:0461 interaction database UBE4B ATXN3 MI:0045 experimental interaction detection MI:0461 interaction database UBE4B HSPA2 MI:0362 inference MI:0461 interaction database UBE4B RAD23A MI:0045 experimental interaction detection MI:0461 interaction database UBE4B RAD23B MI:0362 inference MI:0461 interaction database UBE4B VCP MI:0045 experimental interaction detection MI:0461 interaction database UBE4B DNAJB13 MI:0362 inference MI:0461 interaction database UBE4B UBE2D3 MI:0045 experimental interaction detection MI:0461 interaction database UBE4B UBE2D2 MI:0045 experimental interaction detection MI:0461 interaction database UBE4B RPS27A MI:0362 inference MI:0461 interaction database UBE4B UBA52 MI:0362 inference MI:0461 interaction database UBE4B EEF1A1 MI:0362 inference MI:0461 interaction database UBE4B MAT1A MI:0362 inference MI:0461 interaction database UBE4B MDM2 MI:0045 experimental interaction detection MI:0461 interaction database UBE4B XPC MI:0045 experimental interaction detection MI:0461 interaction database UBE4B UBXN1 MI:0045 experimental interaction detection MI:0461 interaction database UBE4B EEF1A2 MI:0362 inference MI:0461 interaction database UBE4B MAD2L1 MI:0362 inference MI:0461 interaction database UBE4B ITPR1 MI:0362 inference MI:0461 interaction database UBE4B TRIP12 MI:0045 experimental interaction detection MI:0461 interaction database UBE4B ELAVL1 MI:0045 experimental interaction detection MI:0461 interaction database UBE4B TAB1 MI:0362 inference MI:0461 interaction database UBE4B YOD1 MI:0362 inference MI:0461 interaction database UBE4B UBQLNL MI:0362 inference MI:0461 interaction database UBE4B CDKN2A MI:0045 experimental interaction detection MI:0461 interaction database UBE4B NPLOC4 MI:0362 inference MI:0461 interaction database UBE4B DNAJA4 MI:0362 inference MI:0461 interaction database UBE4B HSPH1 MI:0362 inference MI:0461 interaction database UBE4B STAM MI:0045 experimental interaction detection MI:0461 interaction database UBE4B UFD1L MI:0362 inference MI:0461 interaction database UBE4B UBE2E3 MI:0362 inference MI:0461 interaction database UBE4B UBE2W MI:0362 inference MI:0461 interaction database UBE4B UBE2E2 MI:0362 inference MI:0461 interaction database UBE4B UBL7 MI:0045 experimental interaction detection MI:0461 interaction database UBE4B FEZ1 MI:0045 experimental interaction detection MI:0461 interaction database UBE4B TP63 MI:0045 experimental interaction detection MI:0461 interaction database UBE4B ATXN3L MI:0362 inference MI:0461 interaction database UBE4B UBQLN4 MI:0362 inference MI:0461 interaction database UBE4B DNAJB4 MI:0362 inference MI:0461 interaction database UBE4B UBQLN2 MI:0362 inference MI:0461 interaction database UBE4B FBXW11 MI:0045 experimental interaction detection MI:0461 interaction database UBE4B FZR1 MI:0362 inference MI:0461 interaction database UBE4B UBQLN1 MI:0362 inference MI:0461 interaction database UBE4B STUB1 MI:0362 inference MI:0461 interaction database UBE4B NOVA2 MI:0362 inference MI:0461 interaction database UBE4B NSFL1C MI:0362 inference MI:0461 interaction database UBE4B BTRC MI:0045 experimental interaction detection MI:0461 interaction database UBE4B UBE2D4 MI:0362 inference MI:0461 interaction database