DNA & RNA Element - UTRdb Gene Name Type ASPicDB UTRaspic Refseq ID Genome AIRE 3'UTR 988aace315 BA003239 NM_000383 chr21:44542039-44542538:+ AIRE 3'UTR 91e826e486 NM_000383 chr21:44531591-44542530:+ AIRE 3'UTR eeb3126875 NM_000383 chr21:44542039-44542530:+ AIRE 5'UTR 988aace315 CA005449 NM_000383 chr21:44534702-44535117:+

DNA & RNA Element - AREsite Gene Name Motif CDS Area ARE Area Evidence AIRE; APECED ATTTA 128-1765 2207-2211

DNA & RNA Element - microRNA Mirbase Acc miRNA Name Gene ID Gene Symbol miRNA Alignment Alignment Gene Alignment miRNA Start miRNA End Gene Start Gene End Genome Coordinates Conservation Align Score Seed Cat Energy mirSVR Score MIMAT0002891 hsa-miR-18a* 326 AIRE ggUCUUCCUCGUGAAUCCCGUCa :||| :|:: | ||||||| ggGGAACAGGUGGUCAGGGCAGa 2 22 348 370 [hg19:21:45710802-45710824:+] 0.4764 157 7 -19.99 -0.2236 MIMAT0004490 hsa-miR-19a* 326 AIRE acaucacgUUGAUACGUUUUGa ||| | |||||| gucucaaaAACAAAACAAAACa 2 15 1601 1622 [hg19:21:45718011-45718032:+] 0.5026 122 6 -5.81 -0.1130 MIMAT0004490 hsa-miR-19a* 326 AIRE acaucacgUUGAUACGUUUUGa ||| | |||||| gucucaaaAACAAAACAAAACa 2 15 401 422 [hg19:21:45718011-45718032:+] 0.5026 122 6 -5.81 -0.2258 MIMAT0004491 hsa-miR-19b-1* 326 AIRE cgaccuacguuuggacGUUUUGa |||||| gacuccgucucaaaaaCAAAACa 2 8 395 417 [hg19:21:45718005-45718027:+] 0.5026 120 6 -6.55 -0.1727 MIMAT0004492 hsa-miR-19b-2* 326 AIRE acuuuacguuuggacGUUUUGa |||||| acuccgucucaaaaaCAAAACa 2 8 396 417 [hg19:21:45718006-45718027:+] 0.5026 120 6 -6.55 -0.1727 MIMAT0004509 hsa-miR-93* 326 AIRE gcCCUUCACGA--UCGAGUCGUCa | ::|| || :| ||||||| guGUGGGUCCUGAGGGUCAGCAGa 2 21 818 841 [hg19:21:45713036-45713058,45713672-45713672:+] 0.5377 151 7 -22.37 -0.1098 MIMAT0004514 hsa-miR-29b-1* 326 AIRE agaUUUG-GUGGUAUACUUUGGUcg |||| | || | |||||| acaAAACAAAACA-AAAAAACCAca 3 22 1610 1633 [hg19:21:45718020-45718043:+] 0.5026 130 0 -9.92 -0.1647 MIMAT0004514 hsa-miR-29b-1* 326 AIRE agaUUUG-GUGGUAUACUUUGGUcg |||| | || | |||||| acaAAACAAAACA-AAAAAACCAca 3 22 410 433 [hg19:21:45718020-45718043:+] 0.5026 130 0 -9.92 -0.3160 MIMAT0004515 hsa-miR-29b-2* 326 AIRE gauucggugguacacUUUGGUc |||||| caaaacaaaacaaaaAAACCAc 2 8 411 432 [hg19:21:45718021-45718042:+] 0.5026 120 6 -6.37 -0.2007 MIMAT0004552 hsa-miR-139-3p 326 AIRE ugaggUUGUCCCGGCGCAGAGg |::: | |: |||||| gcaagAGUGAGACUCCGUCUCa 2 18 385 406 [hg19:21:45717995-45718016:+] 0.5026 121 6 -16.82 -0.1111 MIMAT0000251 hsa-miR-147 326 AIRE cgucuucguaaaGGUGUGUg |||||:| aaaacaaaaaaaCCACAUAa 2 9 417 436 [hg19:21:45718027-45718046:+] 0.5026 124 0 -10.58 -0.1203 MIMAT0004558 hsa-miR-181a-2* 326 AIRE ccauGUCAGUUG-CCAGUCACCa || |: | | ||||||| cgacCACUUUUCAGUUCAGUGGc 2 19 1653 1675 [hg19:21:45718063-45718085:+] 0.5130 145 7 -14.27 -0.3066 MIMAT0004558 hsa-miR-181a-2* 326 AIRE ccauGUCAGUUG-CCAGUCACCa || |: | | ||||||| cgacCACUUUUCAGUUCAGUGGc 2 19 453 475 [hg19:21:45718063-45718085:+] 0.5130 145 7 -14.27 -0.5309 MIMAT0000270 hsa-miR-181a* 326 AIRE ccaUGUUAGU-UGCCAGCUACCa :|:| || || ||||||| ugaGCGAGCACACCUUCGAUGGc 2 20 1121 1143 [hg19:21:45716321-45716328,45717539-45717553:+] 0.7023 154 7 -15.75 -0.3436 MIMAT0004694 hsa-miR-342-5p 326 AIRE aguuagugucuauCGUGGGGa ||||||| ucaggagggugcuGCACCCCa 2 9 468 488 [hg19:21:45710922-45710942:+] 0.4118 140 7 -20.13 -0.1043 MIMAT0002174 hsa-miR-484 326 AIRE uagcccuccccugaCUCGGACu ||||||| ucccagcuacauggGAGCCUGa 2 9 286 307 [hg19:21:45717896-45717917:+] 0.5116 140 7 -16.93 -0.1595 MIMAT0004762 hsa-miR-486-3p 326 AIRE uaGGAC--AUGACU--CGACGGGGc |||| |:| | ||||||| ugCCUGGAAAUUAAACCCUGCCCCa 2 20 1367 1391 [hg19:21:45717777-45717801:+] 0.5228 141 7 -20.82 -0.4042 MIMAT0004762 hsa-miR-486-3p 326 AIRE uaGGAC--AUGACU--CGACGGGGc |||| |:| | ||||||| ugCCUGGAAAUUAAACCCUGCCCCa 2 20 167 191 [hg19:21:45717777-45717801:+] 0.5228 141 7 -20.82 -0.6591 MIMAT0004764 hsa-miR-490-5p 326 AIRE ugGGUGGACCUCUA-GGUACc ||| ||||: || ||||| auCCA-CUGGGAAUGCCAUGc 2 19 121 140 [hg19:21:45710268-45710287:+] 0.4442 128 0 -21.98 -0.1350 MIMAT0002833 hsa-miR-520a-5p 326 AIRE ucuuUCAUGAAGGGAGACCUc | | || : ||||||| ccccACUUCUCUACUCUGGAa 2 18 1387 1407 [hg19:21:45717797-45717817:+] 0.5148 149 7 -16.54 -0.3933 MIMAT0002833 hsa-miR-520a-5p 326 AIRE ucuuUCAUGAAGGGAGACCUc | | || : ||||||| ccccACUUCUCUACUCUGGAa 2 18 187 207 [hg19:21:45717797-45717817:+] 0.5148 149 7 -16.54 -0.6451 MIMAT0002838 hsa-miR-525-5p 326 AIRE ucuuucacguAGG-GAGACCUc ||: ||||||| gccccacuucUCUACUCUGGAa 2 12 1386 1407 [hg19:21:45717796-45717817:+] 0.5148 142 7 -12.82 -0.3963 MIMAT0002838 hsa-miR-525-5p 326 AIRE ucuuucacguAGG-GAGACCUc ||: ||||||| gccccacuucUCUACUCUGGAa 2 12 186 207 [hg19:21:45717796-45717817:+] 0.5148 142 7 -12.82 -0.6488 MIMAT0002847 hsa-miR-518c* 326 AIRE gucuuUCACGAAGGGAGGUCUCu |||| || ||||||| ccugcAGUG-GGCCAUCCAGAGc 2 19 1146 1167 [hg19:21:45717556-45717577:+] 0.7797 152 7 -20.21 -0.1861 MIMAT0004777 hsa-miR-513a-3p 326 AIRE ggaagagucuuuccacUUUAAAu |||||| aaaaaccacauaacauAAAUUUa 2 8 424 446 [hg19:21:45718034-45718056:+] 0.5026 120 6 -6.92 -0.1227 MIMAT0004779 hsa-miR-509-5p 326 AIRE acuaACGGUGACAGACGUCAu || ||: ||||||| ucgaUGGCAU--CCUGCAGUg 2 18 1136 1154 [hg19:21:45717546-45717564:+] 0.7797 142 7 -16.44 -0.1259 MIMAT0004780 hsa-miR-532-3p 326 AIRE acguucggaaCCCACAC-CCUCc ||||||| |||| gcgcguugcgGGGUGUGCGGAGa 2 13 856 878 [hg19:21:45713687-45713709:+] 0.6377 124 0 -26.04 -0.1897 MIMAT0003231 hsa-miR-567 326 AIRE caagacaggaccuUCUUGUAUga | |||||| acaaaaaaaccacAUAACAUAaa 3 11 1620 1642 [hg19:21:45718030-45718052:+] 0.5026 122 0 -5.22 -0.1121 MIMAT0003231 hsa-miR-567 326 AIRE caagacaggaccuUCUUGUAUga | |||||| acaaaaaaaccacAUAACAUAaa 3 11 420 442 [hg19:21:45718030-45718052:+] 0.5026 122 0 -5.22 -0.2242 MIMAT0004796 hsa-miR-576-3p 326 AIRE cuaAGGUUA-AAAAGGUGUAGAa |:||:| |:||||||| cagUUCAGUGGCAUUCACAUCUc 2 20 1664 1686 [hg19:21:45718074-45718096:+] 0.5130 150 7 -16.67 -0.4874 MIMAT0004796 hsa-miR-576-3p 326 AIRE cuaAGGUUA-AAAAGGUGUAGAa |:||:| |:||||||| cagUUCAGUGGCAUUCACAUCUc 2 20 464 486 [hg19:21:45718074-45718096:+] 0.5130 150 7 -16.67 -0.7504 MIMAT0003256 hsa-miR-589* 326 AIRE agACCCUUGGCCGUAAAC-AAGACu || ||| | : | || ||||| gcUGUAAACAGCUCUGUGUUUCUGg 2 23 125 149 [hg19:21:45717735-45717759:+] 0.5315 122 0 -16.21 -0.1042 MIMAT0003282 hsa-miR-614 326 AIRE ggugGACCGUUCUUGU-CCGCAAg || :||||:|| |||||| caggCUCUUAAGAGCAUGGCGUUu 2 20 20 43 [hg19:21:45710167-45710190:+] 0.5211 135 6 -22.54 -0.2032 MIMAT0003286 hsa-miR-617 326 AIRE cgGUGGA-AGUUUA-CCCUUCAGa |||:| || | | ||||||| ccCACUUCUCUACUCUGGAAGUCc 2 21 188 211 [hg19:21:45717798-45717821:+] 0.5148 154 7 -19.46 -0.1271 MIMAT0004810 hsa-miR-629 326 AIRE ucaagagggUUGCAUUUGGGu || ||||||| ugugccuggAAAUUAAACCCu 2 13 1365 1385 [hg19:21:45717775-45717795:+] 0.5315 144 7 -13.10 -0.2480 MIMAT0004810 hsa-miR-629 326 AIRE ucaagagggUUGCAUUUGGGu || ||||||| ugugccuggAAAUUAAACCCu 2 13 165 185 [hg19:21:45717775-45717795:+] 0.5315 144 7 -13.10 -0.4507 MIMAT0003320 hsa-miR-650 326 AIRE cagGACUCU--CGC---GACG-GAGGa |||||| ||| |||| |||| gagCUGAGAUUGCGCCACUGCACUCCa 2 19 1549 1575 [hg19:21:45717959-45717985:+] 0.5026 124 0 -24.80 -0.1332 MIMAT0003320 hsa-miR-650 326 AIRE cagGACUCU--CGC---GACG-GAGGa |||||| ||| |||| |||| gagCUGAGAUUGCGCCACUGCACUCCa 2 19 349 375 [hg19:21:45717959-45717985:+] 0.5026 124 0 -24.80 -0.2619 MIMAT0003336 hsa-miR-658 326 AIRE ugGUUGCCUGGAUG---AAGGGAGGCGg || | |:|||:| | |||||||| ucCACCUGGCCUGCCUGUCCCCUCCGCu 2 24 597 624 [hg19:21:45711051-45711078:+] 0.7191 166 7 -33.74 -0.1030 MIMAT0004908 hsa-miR-220b 326 AIRE uucaCAGUCUGUGCCACCACc | ::|::::||||||| auuaGCUGGGUGUGGUGGUGg 2 18 1455 1475 [hg19:21:45717865-45717885:+] 0.5156 153 7 -25.56 -0.1199 MIMAT0004908 hsa-miR-220b 326 AIRE uucaCAGUCUGUGCCACCACc | ::|::::||||||| auuaGCUGGGUGUGGUGGUGg 2 18 255 275 [hg19:21:45717865-45717885:+] 0.5156 153 7 -25.56 -0.2383 MIMAT0004917 hsa-miR-888* 326 AIRE aaguggguuucuccACAGUCAg ||||||| acagcgccaccucuUGUCAGUg 2 9 99 120 [hg19:21:45717709-45717730:+] 0.5034 140 7 -15.00 -0.1877 MIMAT0004919 hsa-miR-541* 326 AIRE ucACCCU-GG---CUGUCGUCUUAG-GAAa ||||| || |:|| |||||| ||| caUGGGAGCCUGAGGCAUGAGAAUCACUUg 2 24 1495 1524 [hg19:21:45717905-45717934:+] 0.5076 133 0 -22.59 -0.2150 MIMAT0004919 hsa-miR-541* 326 AIRE ucACCCU-GG---CUGUCGUCUUAG-GAAa ||||| || |:|| |||||| ||| caUGGGAGCCUGAGGCAUGAGAAUCACUUg 2 24 295 324 [hg19:21:45717905-45717934:+] 0.5076 133 0 -22.59 -0.3974 MIMAT0004925 hsa-miR-876-3p 326 AIRE acuuaaugaaacaUUUGGUGgu ||||||| aaacaaaacaaaaAAACCACau 3 10 413 434 [hg19:21:45718023-45718044:+] 0.5026 125 0 -9.28 -0.1601 MIMAT0004948 hsa-miR-885-3p 326 AIRE auAGGUGAUGUGG-GGCGACGGa | | :| |||: ||||||| gcUGCCUUCCACUGGCGCUGCCa 2 21 913 935 [hg19:21:45713744-45713766:+] 0.6714 151 7 -22.58 -0.1063 MIMAT0004972 hsa-miR-922 326 AIRE cugcaucaggauaAG-AGACGACg || ||||||| gacggcggggagcUCAUCUGCUGu 2 11 554 577 [hg19:21:45711008-45711031:+] 0.7676 141 7 -19.13 -0.2171 MIMAT0004975 hsa-miR-509-3-5p 326 AIRE guaCUAACGGUGCAGACGUCAu ||| || | ||||||| uucGAUGGCAUC--CUGCAGUg 2 20 1135 1154 [hg19:21:45717545-45717564:+] 0.7797 148 7 -16.73 -0.1166 MIMAT0005825 hsa-miR-1180 326 AIRE uguGUGGGU-GCGCUCGG-CCUUu || ||| | :| ||| |||| cacCAGCCAUCAUGUGCCUGGAAa 2 20 1353 1376 [hg19:21:45717763-45717786:+] 0.5315 122 0 -21.39 -0.3727 MIMAT0005825 hsa-miR-1180 326 AIRE uguGUGGGU-GCGCUCGG-CCUUu || ||| | :| ||| |||| cacCAGCCAUCAUGUGCCUGGAAa 2 20 153 176 [hg19:21:45717763-45717786:+] 0.5315 122 0 -21.39 -0.6214 MIMAT0005869 hsa-miR-1205 326 AIRE gaGUUUCGUUUGGGACGUCu |:| | : |:||||||| uuCGAUG-GCAUCCUGCAGu 2 19 1135 1153 [hg19:21:45717545-45717563:+] 0.7797 148 7 -21.79 -0.4064 MIMAT0005870 hsa-miR-1206 326 AIRE cgaauuUGUAGAUGUAC-UUGu |||||| |||| ||| gcauucACAUCU-CAUGUAACc 2 16 1674 1694 [hg19:21:45718084-45718104:+] 0.5234 125 0 -12.82 -0.3909 MIMAT0005870 hsa-miR-1206 326 AIRE cgaauuUGUAGAUGUAC-UUGu |||||| |||| ||| gcauucACAUCU-CAUGUAACc 2 16 474 494 [hg19:21:45718084-45718104:+] 0.5234 125 0 -12.82 -0.6396 MIMAT0005871 hsa-miR-1207-5p 326 AIRE ggggagggucggaGGGACGGu ||||||| ccuggaaauuaaaCCCUGCCc 2 9 1369 1389 [hg19:21:45717779-45717799:+] 0.5228 140 7 -18.64 -0.4583 MIMAT0005871 hsa-miR-1207-5p 326 AIRE ggggagggucggaGGGACGGu ||||||| ccuggaaauuaaaCCCUGCCc 2 9 169 189 [hg19:21:45717779-45717799:+] 0.5228 140 7 -18.64 -0.7219 MIMAT0005908 hsa-miR-1257 326 AIRE ccAGUCUUG-GGUAGUAAGUGa |||| | :: ||||||| uuUCAGUUCAGUGGCAUUCACa 2 20 1661 1682 [hg19:21:45718071-45718092:+] 0.5130 146 7 -15.04 -0.2805 MIMAT0005908 hsa-miR-1257 326 AIRE ccAGUCUUG-GGUAGUAAGUGa |||| | :: ||||||| uuUCAGUUCAGUGGCAUUCACa 2 20 461 482 [hg19:21:45718071-45718092:+] 0.5130 146 7 -15.04 -0.4946 MIMAT0005953 hsa-miR-1322 326 AIRE gucguaGUCGUC-GUAGUAg || ||| |||||| uggggaCACCAGCCAUCAUg 2 14 1347 1366 [hg19:21:45717757-45717776:+] 0.5315 121 6 -12.39 -0.1034 MIMAT0005953 hsa-miR-1322 326 AIRE gucguaGUCGUC-GUAGUAg || ||| |||||| uggggaCACCAGCCAUCAUg 2 14 147 166 [hg19:21:45717757-45717776:+] 0.5315 121 6 -12.39 -0.2107 MIMAT0007886 hsa-miR-1911* 326 AIRE ccUCUG-GUGUUACGGACCAc || | | | |||||||| ggAGCCUCUCCUUGCCUGGUg 2 19 1415 1435 [hg19:21:45717825-45717845:+] 0.5156 149 7 -27.74 -0.2599 MIMAT0007886 hsa-miR-1911* 326 AIRE ccUCUG-GUGUUACGGACCAc || | | | |||||||| ggAGCCUCUCCUUGCCUGGUg 2 19 215 235 [hg19:21:45717825-45717845:+] 0.5156 149 7 -27.74 -0.4660 MIMAT0007889 hsa-miR-1914 326 AIRE gucUUCACCCGGCCCGUGUCCc :|| ||: ||||||| cacGAGCCCGCUCUGCACAGGg 2 20 1081 1102 [hg19:21:45716281-45716302:+] 0.6249 147 7 -21.64 -0.1434 MIMAT0009447 hsa-miR-1972 326 AIRE acucGGUGACACGGACC--GGACu |:||||||: ||| |||| ccccCUACUGUGUGUGGGUCCUGa 2 19 807 830 [hg19:21:45713025-45713048:+] 0.6227 122 0 -27.34 -0.1175 MIMAT0009447 hsa-miR-1972 326 AIRE acuCGGUGAC---ACG-GACCG-GACu |||:||| | | ||||| ||| ugcGCCGCUGCCUUCCACUGGCGCUGc 2 20 907 933 [hg19:21:45713738-45713764:+] 0.6714 121 0 -25.61 -0.1063 MIMAT0009977 hsa-miR-2052 326 AIRE uguaaugacaauaGUUUUGu |||||| cucaaaaacaaaaCAAAACa 2 8 1603 1622 [hg19:21:45718013-45718032:+] 0.5026 120 6 -7.76 -0.1141 MIMAT0009977 hsa-miR-2052 326 AIRE uguaaugacaauaGUUUUGu |||||| cucaaaaacaaaaCAAAACa 2 8 403 422 [hg19:21:45718013-45718032:+] 0.5026 120 6 -7.76 -0.2279 MIMAT0014977 hsa-miR-3115 326 AIRE uggUUGAUCAUUUGG-GUAUa ||| | ||||| |||| caaAACAAAAAAACCACAUAa 2 18 1616 1636 [hg19:21:45718026-45718046:+] 0.5026 125 0 -8.80 -1.1775 MIMAT0014977 hsa-miR-3115 326 AIRE uggUUGAUCAUUUGG-GUAUa ||| | ||||| |||| caaAACAAAAAAACCACAUAa 2 18 416 436 [hg19:21:45718026-45718046:+] 0.5026 125 0 -8.80 -1.2741 MIMAT0015009 hsa-miR-548t 326 AIRE guuuuUGGUGCUAGUGAAAAc |:| ||| ||||||| uuaucAUCUCGACCACUUUUc 2 17 1644 1664 [hg19:21:45718054-45718074:+] 0.5026 160 7 -13.18 -0.2006 MIMAT0015009 hsa-miR-548t 326 AIRE guuuuUGGUGCUAGUGAAAAc |:| ||| ||||||| uuaucAUCUCGACCACUUUUc 2 17 444 464 [hg19:21:45718054-45718074:+] 0.5026 160 7 -13.18 -0.3748 MIMAT0015024 hsa-miR-3151 326 AIRE ugGACUAGGGUAACGGGGUGg :| | ||| |||||||| aaUUAAACCC--UGCCCCACu 2 20 1375 1393 [hg19:21:45717785-45717803:+] 0.5228 152 7 -22.45 -0.4393 MIMAT0015024 hsa-miR-3151 326 AIRE ugGACUAGGGUAACGGGGUGg :| | ||| |||||||| aaUUAAACCC--UGCCCCACu 2 20 175 193 [hg19:21:45717785-45717803:+] 0.5228 152 7 -22.45 -0.7002 MIMAT0015028 hsa-miR-3154 326 AIRE agacgaGGGUUGAGGGGAAGAc ||::: :||||||| ggaugaCCUGGAGUCCCUUCUg 2 17 1101 1122 [hg19:21:45716301-45716322:+] 0.6249 148 7 -24.38 -0.1342 MIMAT0015029 hsa-miR-3155 326 AIRE ucaAGGGU-GACGU---CUCGGACc ||||| || || ||||||| uaaUCCCAGCUACAUGGGAGCCUGa 2 19 283 307 [hg19:21:45717893-45717917:+] 0.5116 156 7 -22.04 -0.1564 MIMAT0015057 hsa-miR-3180-5p 326 AIRE gcugcaccccgccucgcAGACCUUc ||||||| cugccccacuucucuacUCUGGAAg 2 9 184 208 [hg19:21:45717794-45717818:+] 0.5204 140 7 -14.88 -0.1277 MIMAT0015075 hsa-miR-3191 326 AIRE gacagACCGGUCG-AUGCAGGGGu || :|| | | ||||||| ugccaUGCUCAUCUUUCGUCCCCa 2 19 133 156 [hg19:21:45710280-45710303:+] 0.4442 153 7 -24.92 -0.7975 MIMAT0015090 hsa-miR-1273d 326 AIRE ugacGUC--GGAGUUGGAGUACC-CAAg ||| :||:|| ||||| ||| uucuCAGGCUCUUAAGAGCAUGGCGUUu 2 22 16 43 [hg19:21:45710163-45710190:+] 0.5211 124 0 -20.52 -0.1994 MIMAT0016848 hsa-miR-4293 326 AIRE gacaAGGACAGUC-CGAc ||:|||||| ||| caccUCUUGUCAGUGCUc 2 14 106 123 [hg19:21:45717716-45717733:+] 0.5034 125 0 -16.32 -0.1236 MIMAT0016849 hsa-miR-4294 326 AIRE gggacgaCA-UCUGAGGg || ||||||| ggcaagaGUGAGACUCCg 2 11 384 401 [hg19:21:45717994-45718011:+] 0.5026 141 7 -13.38 -0.1600 MIMAT0016860 hsa-miR-4307 326 AIRE ccUUUGUCCUUUUUUGUaa ||||| | |||||| aaAAACAAAACAAAACAaa 3 18 1606 1624 [hg19:21:45718016-45718034:+] 0.5026 141 0 -5.57 -0.1014 MIMAT0016860 hsa-miR-4307 326 AIRE ccUUUGUCCUUUUUUGUaa ||||| | |||||| aaAAACAAAACAAAACAaa 3 18 406 424 [hg19:21:45718016-45718034:+] 0.5026 141 0 -5.57 -0.2045 MIMAT0016886 hsa-miR-4252 326 AIRE accacgacUGAGUCACCGg ::|||||||| acuuuucaGUUCAGUGGCa 2 12 1658 1676 [hg19:21:45718068-45718086:+] 0.5130 147 7 -16.34 -0.8622 MIMAT0016886 hsa-miR-4252 326 AIRE accacgacUGAGUCACCGg ::|||||||| acuuuucaGUUCAGUGGCa 2 12 458 476 [hg19:21:45718068-45718086:+] 0.5130 147 7 -16.34 -1.0795 MIMAT0016895 hsa-miR-2355 326 AIRE aacAGGUAACAUAGACCCCUa ||:: ||| |||||||| agcUCUG-UGUUUCUGGGGAc 2 19 1334 1353 [hg19:21:45717744-45717763:+] 0.5315 160 7 -19.15 -0.1649 MIMAT0016895 hsa-miR-2355 326 AIRE aacAGGUAACAUAGACCCCUa ||:: ||| |||||||| agcUCUG-UGUUUCUGGGGAc 2 19 134 153 [hg19:21:45717744-45717763:+] 0.5315 160 7 -19.15 -0.3202 MIMAT0016897 hsa-miR-4269 326 AIRE cgguccCGACAG-ACACGGACg || || |||||||| acaccaGCCAUCAUGUGCCUGg 2 16 1352 1373 [hg19:21:45717762-45717783:+] 0.5315 150 7 -21.94 -0.3812 MIMAT0016897 hsa-miR-4269 326 AIRE cggucCCGACAGACACGGACg ||: || ||||||| gguguGGUGGUGGGUGCCUGu 2 17 263 283 [hg19:21:45717873-45717893:+] 0.5156 152 7 -20.73 -0.1800 MIMAT0016897 hsa-miR-4269 326 AIRE cgguccCGACAG-ACACGGACg || || |||||||| acaccaGCCAUCAUGUGCCUGg 2 16 152 173 [hg19:21:45717762-45717783:+] 0.5315 150 7 -21.94 -0.6321 MIMAT0016904 hsa-miR-4276 326 AIRE cgUGUACUC--AGUG-ACUc :|||||| |||| ||| agGCAUGAGAAUCACUUGAa 2 16 1507 1526 [hg19:21:45717917-45717936:+] 0.5076 122 0 -14.58 -0.3307 MIMAT0016904 hsa-miR-4276 326 AIRE cgUGUACUC--AGUG-ACUc :|||||| |||| ||| agGCAUGAGAAUCACUUGAa 2 16 307 326 [hg19:21:45717917-45717936:+] 0.5076 122 0 -14.58 -0.5633 MIMAT0016910 hsa-miR-4278 326 AIRE guucccguuUGGGGGAUc |||||||| cggcccugcACCCCCUAc 2 10 797 814 [hg19:21:45713015-45713032:+] 0.6134 145 7 -16.87 -0.1010 MIMAT0000242 hsa-miR-129-5p 326 AIRE cguucgggucuggcGUUUUUc |||||| aaaacaaaacaaaaCAAAAAa 2 8 407 427 [hg19:21:45718017-45718037:+] 0.5026 120 6 -5.32 -0.1857 MIMAT0000255 hsa-miR-34a 326 AIRE uguUGGUCGAUUCUGUGACGGu :||| | ||||||||| ccuGCCAAGGAUGACACUGCCa 2 20 1057 1078 [hg19:21:45714378-45714386,45716266-45716278:+] 0.6108 159 7 -23.44 -0.4347 MIMAT0000430 hsa-miR-138 326 AIRE gccggACUAAG--UGUUGUGGUCGa || ||| : :|||||||| cucugUGUUUCUGGGGACACCAGCc 2 19 1336 1360 [hg19:21:45717746-45717770:+] 0.5315 153 7 -20.39 -0.1570 MIMAT0000430 hsa-miR-138 326 AIRE gccggACUAAG--UGUUGUGGUCGa || ||| : :|||||||| cucugUGUUUCUGGGGACACCAGCc 2 19 136 160 [hg19:21:45717746-45717770:+] 0.5315 153 7 -20.39 -0.3065 MIMAT0000431 hsa-miR-140-5p 326 AIRE gaUGGUAUCCCAUUUUGGUGac || | | |||||||| aaACAAAACAAAAAAACCACau 3 21 413 434 [hg19:21:45718023-45718044:+] 0.5026 132 0 -10.61 -0.1617 MIMAT0000435 hsa-miR-143 326 AIRE cucgAUGUCACGAAGUAGAGu || | | : ||||||| aacaUA-AAUUUAUCAUCUCg 2 18 1635 1654 [hg19:21:45718045-45718064:+] 0.5026 143 7 -11.69 -0.8059 MIMAT0000435 hsa-miR-143 326 AIRE cucgAUGUCACGAAGUAGAGu || | | : ||||||| aacaUA-AAUUUAUCAUCUCg 2 18 435 454 [hg19:21:45718045-45718064:+] 0.5026 143 7 -11.69 -1.0382 MIMAT0000686 hsa-miR-34c-5p 326 AIRE cguuagucgaUUGAUGUGACGGa :|: |||||||| gccugccaagGAUGACACUGCCa 2 14 1056 1078 [hg19:21:45714377-45714386,45716266-45716278:+] 0.6108 149 7 -16.89 -0.4347 MIMAT0000687 hsa-miR-299-3p 326 AIRE uucgccaaaugguagGGUGUAu |||||| aacaaaacaaaaaaaCCACAUa 2 8 1614 1635 [hg19:21:45718024-45718045:+] 0.5026 120 6 -13.75 -0.1939 MIMAT0000687 hsa-miR-299-3p 326 AIRE uucgccaaaugguagGGUGUAu |||||| aacaaaacaaaaaaaCCACAUa 2 8 414 435 [hg19:21:45718024-45718045:+] 0.5026 120 6 -13.75 -0.3641 MIMAT0000720 hsa-miR-376c 326 AIRE ugCACCUUAA-AGGAGA-UACAa |||| ||| | ||| |||| caGUGGCAUUCACAUCUCAUGUa 2 20 1669 1691 [hg19:21:45718079-45718101:+] 0.5234 126 0 -12.93 -0.4144 MIMAT0000720 hsa-miR-376c 326 AIRE ugCACCUUAA-AGGAGA-UACAa |||| ||| | ||| |||| caGUGGCAUUCACAUCUCAUGUa 2 20 469 491 [hg19:21:45718079-45718101:+] 0.5234 126 0 -12.93 -0.6679 MIMAT0004693 hsa-miR-330-5p 326 AIRE cgGAUUC--UGUGUCC--GGGUCUCu ||::| :: |||| ||||||| gaCUGGGGAGUUCAGGUACCCAGAGa 2 21 405 430 [hg19:21:45710859-45710884:+] 0.4025 150 7 -29.56 -0.1340 MIMAT0000756 hsa-miR-326 326 AIRE gaCCUC--CUUCCCGGGUCUCc |||| |:| ||||||| ggGGAGUUCAGGUACCCAGAGa 2 19 409 430 [hg19:21:45710863-45710884:+] 0.4025 149 7 -23.82 -0.1327 MIMAT0001541 hsa-miR-449a 326 AIRE ugGUCGAUUGUUA-UGUGACGGu | || || :|| |||||||| gcCUGCCAAGGAUGACACUGCCa 2 21 1056 1078 [hg19:21:45714377-45714386,45716266-45716278:+] 0.6108 163 7 -24.24 -0.4314 MIMAT0003327 hsa-miR-449b 326 AIRE cgGUCGAUUGUUA-UGUGACGGa | || || :|| |||||||| gcCUGCCAAGGAUGACACUGCCa 2 21 1056 1078 [hg19:21:45714377-45714386,45716266-45716278:+] 0.6108 163 7 -22.39 -0.4314 MIMAT0004911 hsa-miR-874 326 AIRE agccagggagcCCGGUCCCGUc ||:||||||| ggggaacagguGGUCAGGGCAg 2 12 348 369 [hg19:21:45710802-45710823:+] 0.4764 151 7 -27.75 -0.2474

DNA & RNA Element - TRANSFAC Accession AS Description Species Entrez Pubmed Binding Info G009545 AIRE Homo sapiens 326 9398839

DNA & RNA Element - TargetScan Gene Name UTR Region Start UTR Region End AIR Total Normalized 3P-seq-tags & Pseudocounts Strand hg19_chromosome Genome Start Genome End AIRE; APECED 1 197 100 23.415 + chr21 45717610 45717807 AIRE; APECED 198 214 86.987 23.415 + chr21 45717807 45717824 AIRE; APECED 215 492 73.974 23.415 + chr21 45717824 45718102 AIRE; APECED 493 918 52.62 23.415 + chr21 45718102 45718528

DNA & RNA Element - RepTar Gene Name miRNA Begin End Profile AIRE ebv-miR-BART19-3p beg:399 end:416 pic:3' TCGTAAGGGTTCGTTTGTTTT 5'& ||.||| |||||||| &5' -----TCTCAA--AAACAAAA 3' AIRE hsa-miR-1248 beg:78 end:97 pic:3' AAATCGTGTCACGAATAT-GTTCTTCCA 5'& ||| |||||||| &5' -----------GCTGGGATCAAGAAGG- 3' AIRE hsa-miR-4294 beg:388 end:401 pic:3' GGGACGACATCTGAGGG 5'& |. ||||||| &5' ----GTG--AGACTCC- 3' AIRE hsa-miR-138 beg:142 end:160 pic:3' GCCGGACTAAGTGTTGTGGTCGA 5'& .|||. .|||||||| &5' ---TCTGGG----GACACCAGC- 3' AIRE hsa-miR-548t beg:446 end:464 pic:3' GTTTTTGGTGCTAGTGAAAAC 5'& |.| ||| ||||||| &5' -----ATCTCGACCACTTTT- 3' AIRE hsa-miR-3169 beg:52 end:70 pic:3' GATACACGGTTCGTGTCAGGAT 5'& || | |||||||. &5' -------CCTTCCTCAGTCCTG 3' AIRE hsa-miR-4252 beg:463 end:476 pic:3' ACCACGACTGAGTCACCGG 5'& | .|||||||| &5' -------G-TTCAGTGGC- 3' AIRE hsa-miR-1207-5p beg:179 end:202 pic:3' GGGGA-GGGTCGGAGGGACGGT 5'& |||. |||| |.||.|| |. &5' CCCTGCCCCA-CTTCTCTACT- 3' AIRE hsa-miR-520a-5p beg:188 end:207 pic:3' TCTTTCATGAAGG---GAGACCTC 5'& |||||. ||||||| &5' -------ACTTCTCTACTCTGGA- 3' AIRE hsa-miR-525-5p beg:193 end:207 pic:3' TCTTTCACGTAGG-GAGACCTC 5'& ||. ||||||| &5' ----------TCTACTCTGGA- 3' AIRE hsa-miR-486-3p beg:181 end:191 pic:3' TAGGACATGACTCGACGGGGC 5'& ||||||| &5' -------------CTGCCCC- 3' AIRE ebv-miR-BART10star beg:321 end:339 pic:3' ACATGTCTTGGTTTCTCCACCG 5'& ||||. .||||||| &5' ------GAACTCGGGAGGTGG- 3' AIRE ebv-miR-BART21-5p beg:215 end:237 pic:3' CAATCAACGGA-AGT----GATCACT 5'& |||| || ||.|||| &5' -------GCCTCTCCTTGCCTGGTGA 3' AIRE hsa-miR-558 beg:10 end:27 pic:3' TAAAACCATGT-CGTCGAGT 5'& || ||| ||||||| &5' -----GGGACATGCAGCTC- 3' AIRE hsa-miR-3151 beg:179 end:194 pic:3' TGGACTAGGGTAACGGGGTGG 5'& ||| ||||||||. &5' -------CCC--TGCCCCACT 3' AIRE hsa-miR-617 beg:194 end:211 pic:3' CGGTG-GAAGTTTACCCTTCAGA 5'& |.|| || ||||||| &5' -CTACTCT-------GGAAGTC- 3' AIRE hsa-miR-220b beg:256 end:276 pic:3' TTCACAGTCTGTGCCACCACC 5'& | .|. .|||||||| &5' ----GCTGGGTGTGGTGGTGG 3' AIRE hsa-miR-4269 beg:265 end:284 pic:3' CGGTCCCGACAGACACGGACG 5'& ||. || |||||||. &5' -----GGTGGTGGGTGCCTGT 3' AIRE hcmv-miR-US5-2 beg:470 end:490 pic:3' CTGTAGCAGTGTGGATAGTATT 5'& |.||| |||||.| ||||. &5' GGCAT--TCACATC--TCATG- 3' AIRE hsa-miR-105 beg:292 end:317 pic:3' TGGTGTCCTCAGACT-CGTAAACT 5'& ||..|||| |||| |||| || &5' --CATGGGAGCCTGAGGCATGAGA 3' AIRE hsa-miR-1205 beg:167 end:188 pic:3' GAGTTTC-GTTTGGGACGTCT 5'& || .|| .||||||||| &5' CTGGAAATTAAACCCTGC--- 3' AIRE hsa-miR-1207-3p beg:66 end:86 pic:3' CTTTACTCCCGGTCGACT 5'& |.|| ||||.||||. &5' GGAAGCC-GGCCGGCTGG 3' AIRE hsa-miR-1226 beg:227 end:237 pic:3' GATCCCTTGTGTCCCGACCACT 5'& ||||||| &5' ---------------CTGGTGA 3' AIRE hsa-miR-1228 beg:295 end:317 pic:3' CCCCCCG--CTCCGTCCACACT 5'& ||| || |||||| || || &5' -GGGAGCCTGAGGCA--TGAGA 3' AIRE hsa-miR-1228 beg:327 end:351 pic:3' CCCC-CCG-CTCCGTCCACACT 5'& ||| ||. ||||. |||| &5' -GGGAGGTGGAGGTTGCAGTGA 3' AIRE hsa-miR-1229 beg:377 end:397 pic:3' GACACCCTCCCGTCACCACTCTC 5'& || |||| |||||| &5' -----GGTCGGCAAGAGTGAGA- 3' AIRE hsa-miR-1233 beg:324 end:344 pic:3' GACGCCCTCCTGTC-CCGAGT 5'& || ||||||| ..| ||.| &5' CT-CGGGAGG-TGGAGGTT-- 3' AIRE hsa-miR-1254 beg:362 end:387 pic:3' TGACGTCCGAGGTC-GAA-GGTCCGA 5'& |||||| |||||| || .| ||| &5' ACTGCA--CTCCAGTCTGGTC-GGC- 3' AIRE hsa-miR-1257 beg:461 end:482 pic:3' CCAGTCTTGGGTA-GTAAGTGA 5'& |||| | ||||||| &5' --TCAGTTCAGTGGCATTCAC- 3' AIRE hsa-miR-1269 beg:454 end:472 pic:3' GGTCATCGTGCCGAGTCAGGTC 5'& ||| .|||||.||| &5' -------CACTTTTCAGTTCAG 3' AIRE hsa-miR-1274a beg:296 end:317 pic:3' ACCGCGGACT-TGTCC-CTG 5'& || |||||| .|| | || &5' -GGAGCCTGAGGCATGAGA- 3' AIRE hsa-miR-1280 beg:259 end:276 pic:3' CCCACCGTCGCCACCCT 5'& |||| | |.|||||| &5' GGGT-GTGGTGGTGGG- 3' AIRE hsa-miR-1297 beg:307 end:327 pic:3' GTGGACTTAATGAACTT 5'& ||. |||| ||||||| &5' CATGAGAATCACTTGAA 3' AIRE hsa-miR-1301 beg:312 end:348 pic:3' CTTCAGTGA----GGGTCCG------TCGACGTT 5'& ||| ||||| |.|.|| .|.||||. &5' GAA-TCACTTGAACTCGGGAGGTGGAGGTTGCAG 3' AIRE hsa-miR-1303 beg:385 end:406 pic:3' TCTCGTTCTGGGGCAGAGATTT 5'& |||| ||||.||||||| &5' AGAGTGAGACTCCGTCTC---- 3' AIRE hsa-miR-1321 beg:468 end:487 pic:3' TAGTGTAAGTGGAGGGAC 5'& .| .||||||| ||.| &5' GTGGCATTCACATCTC-- 3' AIRE hsa-miR-140-5p beg:304 end:323 pic:3' GATGGTATCCCA--TTTTGGTGAC 5'& ||| |.||.|||| &5' -------AGGCATGAGAATCACT- 3' AIRE hsa-miR-143 beg:386 end:407 pic:3' CTCGATGTCACGAAGTAGAGT 5'& |||. || || |.||||| &5' GAGTG--AGA-CTCCGTCTCA 3' AIRE hsa-miR-143star beg:348 end:373 pic:3' TGGTCTCT-ACGTCGTGACGTGG 5'& .|. |||| |||. ||||||||. &5' GCT-GAGATTGCGCCACTGCACT 3' AIRE hsa-miR-181a-2star beg:461 end:475 pic:3' CCATGTCAGTTGCCAGTCACCA 5'& |||| ||||||| &5' ----CAGT------TCAGTGG- 3' AIRE hsa-miR-1825 beg:328 end:350 pic:3' CCTCT-CCTCC--CGTGACCT 5'& ||||. ||||| ||| || &5' GGAGGTGGAGGTTGCAGTG-- 3' AIRE hsa-miR-182star beg:305 end:320 pic:3' ATCAACCGTTCAGATCTTGGT 5'& |||| ||||.|| &5' -----GGCATG---AGAATCA 3' AIRE hsa-miR-184 beg:387 end:405 pic:3' TGGGAATAGTCAA---GAGGCAGGT 5'& ||| |||||||. &5' ---------AGTGAGACTCCGTCT- 3' AIRE hsa-miR-1909 beg:210 end:230 pic:3' GCCACTCGTGGGCCGGGGACGC 5'& ||| |||| |.| .||.||| &5' CGG-GAGC-CTC--TCCTTGC- 3' AIRE hsa-miR-1911star beg:212 end:236 pic:3' CCTCTGGTGTT--ACGGACCAC 5'& |||| || | ||||||||| &5' GGAG-CCTCTCCTTGCCTGGTG 3' AIRE hsa-miR-196b beg:284 end:307 pic:3' GGGTTGTTGT-CCTTTGATGGAT 5'& ||||.| ||| ||.| .|||. &5' CCCAGCTACATGGGA---GCCTG 3' AIRE hsa-miR-196b beg:379 end:401 pic:3' GGGTTGTTGTC-CTTTGATGGAT 5'& .|..||| || ||.||| || &5' -TCGGCAAGAGTGAGACT-CC-- 3' AIRE hsa-miR-197 beg:256 end:277 pic:3' CGACCCACCTCTTCCACCACTT 5'& |||||||| |||||||.. &5' GCTGGGTGT----GGTGGTGGG 3' AIRE hsa-miR-200cstar beg:247 end:272 pic:3' GGTTTGTGA-CGACCCATTCTGC 5'& .||| |.| |||||||. | | &5' -TAAAAATTAGCTGGGTGTGGTG 3' AIRE hsa-miR-205 beg:321 end:342 pic:3' GTCTGAGGCCACCTTACTTCCT 5'& || .||| | .||.||| &5' --GAACTCGG-GAGGTGGAGG- 3' AIRE hsa-miR-211 beg:81 end:100 pic:3' TCCGCTTCCTACTGTTTCCCTT 5'& .|||| .|||||.| &5' ------GGGATCAAGAAGGGGA 3' AIRE hsa-miR-2115 beg:325 end:344 pic:3' AGGTAGTCCTCAGTACCTTCGA 5'& ||.|||| .||||.|.| &5' ----TCGGGAG--GTGGAGGTT 3' AIRE hsa-miR-2115 beg:55 end:75 pic:3' AGGTAGTCCTCAGTACCTTCGA 5'& ||| || |||| ||||||| &5' TCC-TC---AGTCCTGGAAGC- 3' AIRE hsa-miR-216a beg:337 end:361 pic:3' AGTGTCAACGG---TCGACTCTAAT 5'& .||||| ||||||||||. &5' ----GGTTGCAGTGAGCTGAGATTG 3' AIRE hsa-miR-218-1star beg:302 end:321 pic:3' GGTACCACGAACTGCCTTGGTA 5'& || || || ||| |||.|| &5' CC-TGAGGCATGA--GAATCA- 3' AIRE hsa-miR-220c beg:128 end:144 pic:3' TCAGAAGTGTTGTCGGGACACA 5'& ||||||.|||||| &5' ---------AACAGCTCTGTGT 3' AIRE hsa-miR-222 beg:323 end:346 pic:3' TGGGTCATCGGTCTACATCGA 5'& ||.|.| || ..|| || || &5' ACTCGGGAGGTGGAGGTTGC- 3' AIRE hsa-miR-2355 beg:132 end:153 pic:3' AAC-AGGTAACATAGACCCCTA 5'& | ||.. ||| |||||||| &5' --GCTCTG-TGTTTCTGGGGA- 3' AIRE hsa-miR-26b beg:312 end:327 pic:3' TGGATAGGACTTAATGAACTT 5'& |||| ||||||| &5' ---------GAATCACTTGAA 3' AIRE hsa-miR-2861 beg:356 end:375 pic:3' GGCG-GGTGGCGGTCCGGGG 5'& .|| ||||.|| |.|| &5' -TGCGCCACTGCA---CTCC 3' AIRE hsa-miR-298 beg:211 end:233 pic:3' ACCCTCTTGGAGGGACGAAGACGA 5'& ||||| .||||.||| ||| &5' -GGGAGCCTCTCCTTGC--CTG-- 3' AIRE hsa-miR-3065-3p beg:21 end:44 pic:3' GAGGTTGTTATAGGACCACGACT 5'& ||| | | ||||||| &5' CTCTGATGAGAGA---GTGCTGA 3' AIRE hsa-miR-31 beg:98 end:117 pic:3' TCGATACGGTCGTAGAACGGA 5'& ||| |||| | |||||.| &5' AGC---GCCA-CCTCTTGTC- 3' AIRE hsa-miR-3132 beg:179 end:202 pic:3' AGGAGACTCGAGGAAGAGATGGGT 5'& || ||| | |||||||||.| &5' -CC-CTGCCCCACTTCTCTACTC- 3' AIRE hsa-miR-3141 beg:49 end:69 pic:3' AGGAGGAGGTGGG-CGGGAG 5'& ||||||.| |.| |.||| &5' -CCTCCTTC-CTCAGTCCT- 3' AIRE hsa-miR-3151 beg:275 end:298 pic:3' TGGAC--TAGGGTAACGGGGTGG 5'& .|||| |||||| || ||. &5' GCCTGTAATCCCA--GCTACAT- 3' AIRE hsa-miR-3157 beg:362 end:386 pic:3' TCTGACGTGA--TCGGACCGACTT 5'& |||||||| ||.||||. |. &5' --ACTGCACTCCAGTCTGGTCGG- 3' AIRE hsa-miR-3172 beg:169 end:186 pic:3' ATTCCTGACGTTTTGGGGT 5'& ||| ||||||. &5' ---GGAAATT-AAACCCT- 3' AIRE hsa-miR-3172 beg:388 end:401 pic:3' ATTCCTGACGTTTTGGGGT 5'& | |.||.|| &5' --------GTGAGACTCC- 3' AIRE hsa-miR-3180-5p beg:198 end:209 pic:3' GCTGCACCCCGCCTCGCAGACCTTC 5'& |||||||| &5' -----------------TCTGGAAG 3' AIRE hsa-miR-3195 beg:322 end:338 pic:3' TTGGGCCCGGGCCGCGC 5'& |||.|||| ||.| &5' AACTCGGGA--GGTG-- 3' AIRE hsa-miR-3199 beg:50 end:69 pic:3' TTGAAAGAGGATTCCGTCAGGGA 5'& ||||| ||||||. &5' ------CTCCTTCCTCAGTCCT- 3' AIRE hsa-miR-365star beg:188 end:213 pic:3' TGTCGACG-GGGACTTTCAGGGA 5'& || || |.|||.||||||| &5' ACTTCTCTACTCTGGAAGTCCC- 3' AIRE hsa-miR-378 beg:451 end:473 pic:3' GGAAGACTGAGGT----TCAGGTCA 5'& ||| | |||.|||| &5' ------GACCACTTTTCAGTTCAGT 3' AIRE hsa-miR-412 beg:327 end:341 pic:3' TGCCGATCACCTGGTCCACTTCA 5'& ||. |||||.|| &5' ---------GGG--AGGTGGAG- 3' AIRE hsa-miR-4254 beg:327 end:348 pic:3' CTCTACCACCTCATCGAGGTCCG 5'& |.|| ||||||| |.| ||| &5' GGGA-GGTGGAG--GTTGCAG-- 3' AIRE hsa-miR-4258 beg:257 end:276 pic:3' GGTTC-CGCCACCGCCCC 5'& | .| |.|||||.||| &5' CTGGGTGTGGTGGTGGG- 3' AIRE hsa-miR-4259 beg:275 end:294 pic:3' AGGACTGGGGATCTGGGTTGAC 5'& .||. || ||||.|| &5' -----GCCTGTAATCCCAGCT- 3' AIRE hsa-miR-4260 beg:389 end:408 pic:3' ACCCTGAGGTACGGGGTTC 5'& || |||||| |.|.||| &5' TGAGACTCC--GTCTCAA- 3' AIRE hsa-miR-4263 beg:299 end:318 pic:3' CCGG-TTCCGTGAATCTTA 5'& ||| .|||||. ||||| &5' -GCCTGAGGCATG-AGAAT 3' AIRE hsa-miR-4269 beg:152 end:173 pic:3' CGGTCCCGACAGACACGGACG 5'& |||| |||||||| &5' -CCAGCCATCA-TGTGCCTG- 3' AIRE hsa-miR-4271 beg:47 end:63 pic:3' GGGGTGGAAAAGAAGGGGG 5'& ||||| |||||.| &5' ---CACCTC--CTTCCTC- 3' AIRE hsa-miR-4280 beg:355 end:374 pic:3' CGAGACGAGTCTTGATGTGAG 5'& .||| |||.||||| &5' ---TTGCGCC--ACTGCACTC 3' AIRE hsa-miR-4284 beg:258 end:281 pic:3' TACCC-CACTA-CACTCG-GG 5'& |||| |||.| |||.|. || &5' -TGGGTGTGGTGGTGGGTGCC 3' AIRE hsa-miR-4284 beg:332 end:354 pic:3' TACC-CCACTA-CACTCGGG 5'& .||| ||| ||||||. &5' GTGGAGGTTGCAGTGAGCT- 3' AIRE hsa-miR-4304 beg:61 end:78 pic:3' ACGGGACCTGTACGGCC 5'& |.|||||| ||||| &5' -GTCCTGGAA--GCCGG 3' AIRE hsa-miR-4305 beg:255 end:273 pic:3' CTTGACCTCCACAGATCC 5'& |.||||. ||| || &5' -AGCTGGGTGTGGT--GG 3' AIRE hsa-miR-4305 beg:321 end:342 pic:3' CTTGA--CCTCCACAGATCC 5'& ||||| ||||||| ||| &5' GAACTCGGGAGGTGG--AGG 3' AIRE hsa-miR-4315 beg:285 end:304 pic:3' CAGGTCGA-GT-CTTTCGCC 5'& |||||| || | ||| &5' --CCAGCTACATGGGAGC-- 3' AIRE hsa-miR-4316 beg:368 end:387 pic:3' GTGGTC-GATCGGAGTGG 5'& | |||| ||.|.| .| &5' CTCCAGTCTGGTCG-GC- 3' AIRE hsa-miR-432star beg:328 end:352 pic:3' TCTGTACCTCCT-CGGTAGGTC 5'& .|| .|||||| || . || &5' GGAGGTGGAGGTTGCAG-TGAG 3' AIRE hsa-miR-4330 beg:17 end:36 pic:3' CGTTCCGAGACTAGACTCC 5'& ||| |||||||| ||| &5' GCA--GCTCTGATGAGAG- 3' AIRE hsa-miR-512-5p beg:256 end:267 pic:3' CTTTCACGGGAGTTCCGACTCAC 5'& ||||.||| &5' ---------------GCTGGGTG 3' AIRE hsa-miR-518e beg:323 end:346 pic:3' GTGAGA-CTTC-CCTTC-GCGAAA 5'& |||| ||.| |||.| .|| &5' -ACTCGGGAGGTGGAGGTTGC--- 3' AIRE hsa-miR-518f beg:21 end:42 pic:3' GGAGATTTCTCT-TCGCGAAAG 5'& ||||.| |||| ||.||| &5' -CTCTGATGAGAGAGTGCT--- 3' AIRE hsa-miR-520a-5p beg:132 end:152 pic:3' TCTTTCATGA-AGGGAGACCTC 5'& || || | ..|||||.| &5' ----AGCTCTGTGTTTCTGGGG 3' AIRE hsa-miR-532-5p beg:295 end:314 pic:3' TGCCA--GGATGTGAGTTCCGTAC 5'& |.|| ||| .||||||| &5' ATGGGAGCCT------GAGGCATG 3' AIRE hsa-miR-542-5p beg:197 end:215 pic:3' AGAGCACTGTACTACTAGGGGCT 5'& ||| ||. .||||||. &5' -CTC-TGGAA-----GTCCCCGG 3' AIRE hsa-miR-550star beg:373 end:398 pic:3' TACACGGACT--CC---CTCATTCTGT 5'& |.|||. || ||||.|||| &5' ----GTCTGGTCGGCAAGAGTGAGAC- 3' AIRE hsa-miR-555 beg:212 end:232 pic:3' TAGTCTCCAAGTCGAATGGGA 5'& .||| || |||.||. &5' ---GGAGCCTCTCCTTGCCT- 3' AIRE hsa-miR-567 beg:0 end:22 pic:3' CAAGACAGG---ACCT-TCTTGTATGA 5'& || ||| .|.||||.| &5' -------CCAGATGGCCGGGACATGC- 3' AIRE hsa-miR-576-3p beg:464 end:486 pic:3' CTAAGGTTAAAA-AGGTGTAGAA 5'& |.||.| |.||||||| &5' ---TTCAGTGGCATTCACATCT- 3' AIRE hsa-miR-593star beg:256 end:282 pic:3' CGACTCGTTACGGACCGACCACGGA 5'& ||||.|. .|| |||. ||||||| &5' GCTGGGT-GTGG-TGGTGGGTGCCT 3' AIRE hsa-miR-595 beg:352 end:374 pic:3' TCT-GTGTGGTGCCGTGTGAAG 5'& ||| ..|.|||| |||| | &5' AGATTGCGCCACTGCACTC--- 3' AIRE hsa-miR-596 beg:324 end:344 pic:3' GGGCTCCTCGGCCCGTCCGAA 5'& |.|| |||| .|| |||.| &5' CTCG-GGAGGTGG--AGGTT- 3' AIRE hsa-miR-596 beg:0 end:22 pic:3' GGGCTCC-TCGGCCC-GTCCGAA 5'& ||| || .|||||| || || &5' CCCCAGATGGCCGGGACATGC-- 3' AIRE hsa-miR-615-3p beg:384 end:406 pic:3' TTCTCCCTCTGGGTCCGAGCCT 5'& ||||| |||||.| | ||| &5' AAGAGTGAGACTCCGTCTC--- 3' AIRE hsa-miR-630 beg:21 end:42 pic:3' TGGAAGGGACCA-TGTCTTATGA 5'& |.||| | |||.|.|| &5' -----CTCTGATGAGAGAGTGCT 3' AIRE hsa-miR-668 beg:460 end:477 pic:3' CATCACCCGGCTCGGCTCACTGT 5'& .| ||. ||||.|| &5' --------TC-AGTTCAGTGGCA 3' AIRE hsa-miR-718 beg:321 end:342 pic:3' GCTGCGGGCCGCCCCGCCTTC 5'& || |.||| | ||.|||.| &5' -GAA-CTCGG-GAGGTGGAGG 3' AIRE hsa-miR-720 beg:333 end:352 pic:3' ACCTCCGGGGTCGCTCT 5'& ||||||.. |||.||| &5' TGGAGGTTGCAGTGAG- 3' AIRE hsa-miR-765 beg:180 end:200 pic:3' GTAGTGGAA-GGAAGAGGAGGT 5'& | ||| || ||.|||.| &5' ---C-CCTGCCCCACTTCTCTA 3' AIRE hsa-miR-877 beg:179 end:201 pic:3' GGGACGCGGTAGAGGAGATG 5'& |||||| ||| ||.|||||| &5' CCCTGCCCCA-CTTCTCTAC 3' AIRE hsa-miR-888star beg:100 end:120 pic:3' AAGTGGGTTTCTCCACAGTCAG 5'& |.|| ||||||| &5' --CGCCACCTCT--TGTCAGT- 3' AIRE hsa-miR-891b beg:325 end:347 pic:3' AGTTACTGAGTCCA-----TTCAACGT 5'& ||||.|| |.|||||| &5' ------ACTCGGGAGGTGGAGGTTGCA 3' AIRE hsa-miR-92bstar beg:361 end:384 pic:3' GTGACGTGGCG-CAGGGCAGGGA 5'& ||||||||. |||. ||| &5' CACTGCACTCCAGTCTGGTC--- 3' AIRE hsv1-miR-H12 beg:386 end:408 pic:3' TTCGCAAGCGTGAAGCAGGGTT 5'& .||.| | ||| ||||.||| &5' GAGTGA--G-ACTCCGTCTCAA 3' AIRE hsv1-miR-H13 beg:0 end:30 pic:3' GGTCA--CGAGC---GTGAAGCGGGATT 5'& |||| || || ||. ||.||.| &5' CCAGATGGC-CGGGACATGCAGCTCTGA 3' AIRE kshv-miR-K12-12 beg:213 end:235 pic:3' GCCTCTCCTTACCACCGGACCAA 5'& |||| ||||||| &5' -GGAGCCTCTCCTT-GCCTGGT- 3' AIRE kshv-miR-K12-12star beg:43 end:64 pic:3' AGTTGGTCCCGTG--GGAGGGGGT 5'& ||| ||| |||.||.|| &5' ------AGGACACCTCCTTCCTCA 3' AIRE kshv-miR-K12-7 beg:70 end:91 pic:3' CGCGGTC-GTTGTACCCTAGT 5'& |||.| |..| |||||||| &5' --GCCGGCCGGC-TGGGATCA 3' AIRE kshv-miR-K12-8 beg:155 end:174 pic:3' ACGAGAGAGTCAGCGCGGATC 5'& || | ||| .|.||||.| &5' -GC-CA-TCA--TGTGCCTGG 3' AIRE kshv-miR-K12-8star beg:256 end:276 pic:3' TCGCCCCGCAATCACT-CCCTCA 5'& ||| |||.| |.|||. ||| &5' AGCTGGGTG-TGGTGGTGGG--- 3' AIRE hsa-miR-629 beg:166 end:185 pic:3' TCAAGAGGGTTGC--ATTTGGGT 5'& || . ||||||| &5' ------CCTGGAAATTAAACCC- 3'

DNA & RNA Element - miRcode Gene Name Type microRNA Seed Position Seed Type Total Cons% Tr Region AIRE High_conserved miR-503 chr21:45710213 7-mer-m8 7 5pUTR AIRE High_conserved miR-503 chr21:45718469 7-mer-A1 9 ncRNA AIRE High_conserved miR-132/212/212-3p chr21:45708451 7-mer-m8 0 ncRNA AIRE High_conserved miR-7/7ab chr21:45707061 7-mer-m8 4 ncRNA AIRE High_conserved miR-9/9ab chr21:45706861 7-mer-A1 33 CDS, ncRNA AIRE High_conserved miR-9/9ab chr21:45710981 7-mer-A1 13 CDS AIRE High_conserved miR-93/93a/105/106a/291a-3p/294/295/302abcde/372/373/428/519a/520be/520acd-3p/1378/1420ac chr21:45710408 7-mer-A1 9 5pUTR AIRE High_conserved miR-138/138ab chr21:45717770 7-mer-m8 11 3pUTR, ncRNA AIRE High_conserved miR-143/1721/4770 chr21:45708872 7-mer-A1 2 ncRNA AIRE High_conserved miR-143/1721/4770 chr21:45718064 7-mer-m8 2 3pUTR, ncRNA AIRE High_conserved miR-143/1721/4770 chr21:45718097 7-mer-A1 9 3pUTR, ncRNA AIRE High_conserved miR-148ab-3p/152 chr21:45708514 7-mer-A1 9 ncRNA AIRE High_conserved miR-150/5127 chr21:45710555 7-mer-A1 9 5pUTR AIRE High_conserved miR-15abc/16/16abc/195/322/424/497/1907 chr21:45708667 7-mer-m8 4 ncRNA AIRE High_conserved miR-15abc/16/16abc/195/322/424/497/1907 chr21:45710892 7-mer-m8 11 CDS AIRE High_conserved miR-15abc/16/16abc/195/322/424/497/1907 chr21:45718469 8-mer 9 ncRNA AIRE High_conserved miR-183 chr21:45708809 7-mer-m8 13 ncRNA AIRE High_conserved miR-183 chr21:45708856 7-mer-m8 11 ncRNA AIRE High_conserved miR-187 chr21:45712951 7-mer-A1 4 CDS, ncRNA AIRE High_conserved miR-192/215 chr21:45710265 7-mer-A1 7 5pUTR AIRE High_conserved miR-199ab-5p chr21:45707176 8-mer 11 ncRNA AIRE High_conserved miR-199ab-5p chr21:45707303 7-mer-A1 7 ncRNA AIRE High_conserved miR-1ab/206/613 chr21:45708867 7-mer-A1 9 ncRNA AIRE High_conserved miR-203 chr21:45709299 7-mer-A1 9 ncRNA AIRE High_conserved miR-204/204b/211 chr21:45707289 7-mer-m8 20 ncRNA AIRE High_conserved miR-205/205ab chr21:45706459 7-mer-A1 38 CDS, ncRNA AIRE High_conserved miR-214/761/3619-5p chr21:45706509 7-mer-A1 22 CDS, ncRNA AIRE High_conserved miR-214/761/3619-5p chr21:45708488 7-mer-A1 7 ncRNA AIRE High_conserved miR-214/761/3619-5p chr21:45708668 7-mer-A1 4 ncRNA AIRE High_conserved miR-214/761/3619-5p chr21:45709503 7-mer-m8 11 ncRNA AIRE High_conserved miR-216a chr21:45717970 7-mer-m8 2 3pUTR, ncRNA AIRE High_conserved miR-218/218a chr21:45708929 7-mer-m8 4 ncRNA AIRE High_conserved miR-219-5p/508/508-3p/4782-3p chr21:45709382 7-mer-m8 11 ncRNA AIRE High_conserved miR-221/222/222ab/1928 chr21:45708714 7-mer-A1 2 ncRNA AIRE High_conserved miR-221/222/222ab/1928 chr21:45718333 7-mer-A1 7 ncRNA AIRE High_conserved miR-122/122a/1352 chr21:45709069 7-mer-m8 9 ncRNA AIRE High_conserved miR-122/122a/1352 chr21:45709586 7-mer-m8 29 CDS, ncRNA AIRE High_conserved miR-122/122a/1352 chr21:45717985 7-mer-A1 2 3pUTR, ncRNA AIRE High_conserved miR-24/24ab/24-3p chr21:45709515 7-mer-A1 11 ncRNA AIRE High_conserved miR-26ab/1297/4465 chr21:45717936 7-mer-A1 4 3pUTR, ncRNA AIRE High_conserved miR-31 chr21:45710970 7-mer-m8 16 CDS AIRE High_conserved miR-103a/107/107ab chr21:45705978 7-mer-A1 44 CDS, ncRNA AIRE High_conserved miR-103a/107/107ab chr21:45710891 7-mer-m8 9 CDS AIRE High_conserved miR-103a/107/107ab chr21:45710937 7-mer-A1 13 CDS AIRE High_conserved miR-103a/107/107ab chr21:45714282 7-mer-A1 11 ncRNA AIRE High_conserved miR-103a/107/107ab chr21:45718468 7-mer-m8 9 ncRNA AIRE High_conserved miR-338/338-3p chr21:45708904 7-mer-A1 7 ncRNA AIRE High_conserved miR-33a-3p/365/365-3p chr21:45708865 7-mer-m8 9 ncRNA AIRE High_conserved miR-34ac/34bc-5p/449abc/449c-5p chr21:45709487 7-mer-A1 13 ncRNA AIRE High_conserved miR-34ac/34bc-5p/449abc/449c-5p chr21:45710674 7-mer-m8 16 5pUTR AIRE High_conserved miR-34ac/34bc-5p/449abc/449c-5p chr21:45716278 8-mer 7 3pUTR, CDS, ncRNA AIRE High_conserved miR-10abc/10a-5p chr21:45708682 7-mer-A1 4 ncRNA AIRE High_conserved miR-128/128ab chr21:45708977 7-mer-m8 7 ncRNA AIRE High_conserved miR-129-5p/129ab-5p chr21:45718037 7-mer-A1 2 3pUTR, ncRNA AIRE High_conserved miR-490-3p chr21:45709566 7-mer-m8 22 CDS, ncRNA AIRE Medium_conserved miR-504/4725-5p chr21:45707050 7-mer-m8 4 ncRNA AIRE Medium_conserved miR-504/4725-5p chr21:45713054 7-mer-A1 2 CDS, ncRNA AIRE Medium_conserved miR-590-3p chr21:45717868 7-mer-A1 7 3pUTR, ncRNA AIRE Medium_conserved miR-134/3118 chr21:45708598 7-mer-m8 11 ncRNA AIRE Medium_conserved miR-134/3118 chr21:45716284 7-mer-m8 4 3pUTR, CDS, ncRNA AIRE Medium_conserved miR-873 chr21:45709153 7-mer-m8 7 ncRNA AIRE Medium_conserved miR-873 chr21:45718143 7-mer-A1 9 ncRNA AIRE Medium_conserved miR-874 chr21:45708821 7-mer-m8 13 ncRNA AIRE Medium_conserved miR-874 chr21:45709905 7-mer-m8 20 CDS, ncRNA AIRE Medium_conserved miR-874 chr21:45710593 7-mer-m8 11 5pUTR AIRE Medium_conserved miR-874 chr21:45710823 7-mer-m8 0 CDS AIRE Medium_conserved miR-874 chr21:45710857 7-mer-m8 16 CDS AIRE Medium_conserved miR-149 chr21:45708465 7-mer-A1 11 ncRNA AIRE Medium_conserved miR-149 chr21:45709517 7-mer-m8 11 ncRNA AIRE Medium_conserved miR-149 chr21:45710426 7-mer-m8 0 5pUTR AIRE Medium_conserved miR-197 chr21:45707229 7-mer-A1 7 ncRNA AIRE Medium_conserved miR-290-5p/292-5p/371-5p/293 chr21:45708338 7-mer-m8 36 CDS, ncRNA AIRE Medium_conserved miR-299/299-3p/3563-3p chr21:45708565 7-mer-m8 9 ncRNA AIRE Medium_conserved miR-299/299-3p/3563-3p chr21:45718045 7-mer-A1 0 3pUTR, ncRNA AIRE Medium_conserved miR-326/330/330-5p chr21:45708259 7-mer-A1 36 CDS, ncRNA AIRE Medium_conserved miR-326/330/330-5p chr21:45710884 8-mer 13 CDS AIRE Medium_conserved miR-339b/339-5p/3586-5p chr21:45716303 7-mer-A1 29 3pUTR, CDS, ncRNA AIRE Medium_conserved miR-340-5p chr21:45709223 8-mer 9 ncRNA AIRE Medium_conserved miR-342-3p chr21:45718500 7-mer-m8 9 ncRNA AIRE Medium_conserved miR-346 chr21:45708844 7-mer-m8 11 ncRNA AIRE Medium_conserved miR-346 chr21:45718426 7-mer-A1 7 ncRNA AIRE Medium_conserved miR-370 chr21:45708330 7-mer-m8 33 CDS, ncRNA AIRE Medium_conserved miR-370 chr21:45708828 7-mer-m8 9 ncRNA AIRE Medium_conserved miR-370 chr21:45709902 7-mer-m8 18 CDS, ncRNA AIRE Medium_conserved miR-370 chr21:45710575 7-mer-m8 9 5pUTR AIRE Medium_conserved miR-370 chr21:45710631 7-mer-m8 9 5pUTR AIRE Medium_conserved miR-376abd/376b-3p chr21:45718229 7-mer-m8 4 ncRNA AIRE Medium_conserved miR-376abd/376b-3p chr21:45718473 7-mer-A1 9 ncRNA AIRE Medium_conserved miR-377 chr21:45718499 7-mer-m8 9 ncRNA AIRE Medium_conserved miR-378/422a/378bcdefhi chr21:45708257 8-mer 40 CDS, ncRNA AIRE Medium_conserved miR-378/422a/378bcdefhi chr21:45712228 7-mer-m8 16 CDS, ncRNA AIRE Medium_conserved miR-421 chr21:45709355 8-mer 4 ncRNA AIRE Medium_conserved miR-485-5p/1698/1703/1962 chr21:45707185 7-mer-m8 16 ncRNA AIRE Medium_conserved miR-485-5p/1698/1703/1962 chr21:45709179 7-mer-m8 11 ncRNA AIRE Medium_conserved miR-491-5p chr21:45705799 7-mer-A1 11 5pUTR, ncRNA AIRE Medium_conserved miR-491-5p chr21:45706943 7-mer-m8 7 CDS, ncRNA AIRE Medium_conserved miR-491-5p chr21:45707095 7-mer-m8 9 ncRNA AIRE Medium_conserved miR-491-5p chr21:45708571 7-mer-m8 4 ncRNA

DNA & RNA Element - RAID2 Gene Name RAID ID Interactor 1 Category 1 ID 1 Interactor 2 Category 2 ID 2 Methods Score AIRE RAID00107312 hsa-miR-4645-5p miRNA MIMAT0019705 AIRE mRNA 326 Prediction 0.1828 AIRE RAID00135975 hsa-miR-873-5p miRNA MIMAT0004953 AIRE mRNA 326 Prediction 0.1828 AIRE RAID00319510 hsa-miR-181a-2-3p miRNA MIMAT0004558 AIRE mRNA 326 Prediction 0.1828 AIRE RAID00619142 hsa-miR-34c-5p miRNA MIMAT0000686 AIRE mRNA 326 Prediction 0.1828 AIRE RAID00760022 hsa-miR-449a miRNA MIMAT0001541 AIRE mRNA 326 Prediction 0.1828 AIRE RAID00908572 hsa-miR-326 miRNA MIMAT0000756 AIRE mRNA 326 Prediction 0.1828 AIRE RAID01056611 hsa-miR-339-5p miRNA MIMAT0000764 AIRE mRNA 326 Prediction 0.1828 AIRE RAID01480132 hsa-miR-4673 miRNA MIMAT0019755 AIRE mRNA 326 Prediction 0.1828 AIRE RAID02054360 hsa-miR-874-3p miRNA MIMAT0004911 AIRE mRNA 326 Prediction 0.1828 AIRE RAID02153655 hsa-miR-520a-5p miRNA MIMAT0002833 AIRE mRNA 326 Prediction 0.1828 AIRE RAID02321960 hsa-miR-4252 miRNA MIMAT0016886 AIRE mRNA 326 Prediction 0.1828 AIRE RAID02605601 hsa-miR-138-5p miRNA MIMAT0000430 AIRE mRNA 326 Prediction 0.1828 AIRE RAID02792336 hsa-miR-449b-5p miRNA MIMAT0003327 AIRE mRNA 326 Prediction 0.1828 AIRE RAID02831442 hsa-miR-299-3p miRNA MIMAT0000687 AIRE mRNA 326 Prediction 0.1828 AIRE RAID02888830 hsa-miR-3682-3p miRNA MIMAT0018110 AIRE mRNA 326 Prediction 0.1828 AIRE RAID03194698 hsa-miR-3151-5p miRNA MIMAT0015024 AIRE mRNA 326 Prediction 0.1828 AIRE RAID03275253 hsa-miR-129-5p miRNA MIMAT0000242 AIRE mRNA 326 Prediction 0.1828 AIRE RAID03308589 hsa-miR-143-3p miRNA MIMAT0000435 AIRE mRNA 326 Prediction 0.1828 AIRE RAID03311950 hsa-miR-330-5p miRNA MIMAT0004693 AIRE mRNA 326 Prediction 0.1828 AIRE RAID03504559 hsa-miR-1911-3p miRNA MIMAT0007886 AIRE mRNA 326 Prediction 0.1828 AIRE RAID03548449 hsa-miR-140-5p miRNA MIMAT0000431 AIRE mRNA 326 Prediction 0.1828 AIRE RAID03760663 hsa-miR-376c-3p miRNA MIMAT0000720 AIRE mRNA 326 Prediction 0.1828 AIRE RAID03805703 hsa-miR-212-5p miRNA MIMAT0022695 AIRE mRNA 326 Prediction 0.1828 AIRE RAID03808911 hsa-miR-4294 miRNA MIMAT0016849 AIRE mRNA 326 Prediction 0.1828 AIRE RAID03915607 hsa-miR-34a-5p miRNA MIMAT0000255 AIRE mRNA 326 Prediction 0.1828 AIRE RAID05081414 CRNDE lncRNA 643911 AIRE protein 326 Microarray//RNA-seq 0.6606