Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change ACC 16 2282180 2282180 + Missense_Mutation SNP C C A TCGA-OR-A5JT-01A-11D-A29I-10 TCGA-OR-A5JT-10A-01D-A29L-10 g.chr16:2282180C>A c.424C>A c.(424-426)Cac>Aac p.H142N ACC 16 2282180 2282180 + Missense_Mutation SNP C C A TCGA-P6-A5OF-01A-11D-A29I-10 TCGA-P6-A5OF-10A-01D-A29L-10 g.chr16:2282180C>A c.424C>A c.(424-426)Cac>Aac p.H142N ACC 16 2284352 2284352 + Missense_Mutation SNP A A G TCGA-OR-A5KB-01A-11D-A30A-10 TCGA-OR-A5KB-11A-11D-A30A-10 g.chr16:2284352A>G c.1556A>G c.(1555-1557)tAc>tGc p.Y519C BLCA 16 2273626 2273626 + Silent SNP G G A TCGA-ZF-AA4X-01A-11D-A38G-08 TCGA-ZF-AA4X-10A-01D-A38J-08 g.chr16:2273626G>A c.12G>A c.(10-12)gcG>gcA p.A4A BLCA 16 2279581 2279581 + Missense_Mutation SNP C C T TCGA-KQ-A41R-01A-21D-A34U-08 TCGA-KQ-A41R-10G-01D-A34X-08 g.chr16:2279581C>T c.320C>T c.(319-321)gCa>gTa p.A107V BLCA 16 2279640 2279640 + Silent SNP C C T TCGA-DK-AA6U-01A-11D-A391-08 TCGA-DK-AA6U-10A-01D-A394-08 g.chr16:2279640C>T c.379C>T c.(379-381)Ctg>Ttg p.L127L BLCA 16 2284316 2284316 + Missense_Mutation SNP G G A TCGA-FD-A5BV-01A-11D-A26M-08 TCGA-FD-A5BV-10A-01D-A26K-08 g.chr16:2284316G>A c.1520G>A c.(1519-1521)cGt>cAt p.R507H BLCA 16 2284977 2284977 + Missense_Mutation SNP C C A TCGA-UY-A78N-01A-12D-A339-08 TCGA-UY-A78N-10A-01D-A339-08 g.chr16:2284977C>A c.1910C>A c.(1909-1911)gCt>gAt p.A637D BLCA 16 2285351 2285351 + Silent SNP C C T TCGA-K4-A83P-01A-11D-A34U-08 TCGA-K4-A83P-10A-01D-A34X-08 g.chr16:2285351C>T c.2133C>T c.(2131-2133)atC>atT p.I711I BLCA 16 2285495 2285495 + Frame_Shift_Del DEL C C - TCGA-DK-AA75-01A-11D-A391-08 TCGA-DK-AA75-10A-01D-A394-08 g.chr16:2285495delC c.2277delC c.(2275-2277)atcfs p.I759fs BRCA 16 2282221 2282221 + Silent SNP A A G TCGA-A2-A0T5-01A-21D-A099-09 TCGA-A2-A0T5-10A-01D-A099-09 g.chr16:2282221A>G c.465A>G c.(463-465)ggA>ggG p.G155G BRCA 16 2283116 2283116 + Missense_Mutation SNP A A G TCGA-E9-A3HO-01A-11D-A20S-09 TCGA-E9-A3HO-10A-02D-A20S-09 g.chr16:2283116A>G c.988A>G c.(988-990)Acc>Gcc p.T330A BRCA 16 2283890 2283890 + Missense_Mutation SNP C C T TCGA-BH-A18G-01A-11D-A12B-09 TCGA-BH-A18G-10A-01D-A12B-09 g.chr16:2283890C>T c.1274C>T c.(1273-1275)gCc>gTc p.A425V BRCA 16 2284337 2284337 + Missense_Mutation SNP C C T TCGA-E2-A1L7-01A-11D-A142-09 TCGA-E2-A1L7-10A-01D-A142-09 g.chr16:2284337C>T c.1541C>T c.(1540-1542)tCa>tTa p.S514L BRCA 16 2285081 2285081 + Splice_Site SNP G G A TCGA-BH-A18G-01A-11D-A12B-09 TCGA-BH-A18G-10A-01D-A12B-09 g.chr16:2285081G>A c.e13-1 CESC 16 2283533 2283533 + Missense_Mutation SNP G G C TCGA-C5-A1BM-01A-11D-A13W-08 TCGA-C5-A1BM-10A-01D-A13W-08 g.chr16:2283533G>C c.1151G>C c.(1150-1152)cGc>cCc p.R384P CESC 16 2285568 2285568 + Missense_Mutation SNP G G A TCGA-EA-A3HU-01A-11D-A20U-09 TCGA-EA-A3HU-10B-01D-A20U-09 g.chr16:2285568G>A c.2350G>A c.(2350-2352)Gtc>Atc p.V784I COAD 16 2279661 2279661 + Missense_Mutation SNP G G A TCGA-AD-6895-01A-11D-1924-10 TCGA-AD-6895-10A-01D-1924-10 g.chr16:2279661G>A c.400G>A c.(400-402)Gca>Aca p.A134T COAD 16 2282275 2282275 + Silent SNP C C T TCGA-A6-6781-01A-22D-1924-10 TCGA-A6-6781-10A-01D-1924-10 g.chr16:2282275C>T c.519C>T c.(517-519)ctC>ctT p.L173L COAD 16 2282575 2282575 + Missense_Mutation SNP C C T TCGA-AZ-4323-01A-21D-1835-10 TCGA-AZ-4323-10A-01D-1835-10 g.chr16:2282575C>T c.728C>T c.(727-729)aCg>aTg p.T243M COAD 16 2283133 2283133 + Silent SNP C C T TCGA-AA-3663-01A-01D-1719-10 TCGA-AA-3663-11A-01D-1719-10 g.chr16:2283133C>T c.1005C>T c.(1003-1005)gtC>gtT p.V335V COAD 16 2283533 2283533 + Missense_Mutation SNP G G A TCGA-DM-A28G-01A-11D-A16V-10 TCGA-DM-A28G-10A-01D-A16V-10 g.chr16:2283533G>A c.1151G>A c.(1150-1152)cGc>cAc p.R384H COAD 16 2283540 2283541 + Frame_Shift_Ins INS - - G TCGA-AA-3492-01A-01D-1408-10 TCGA-AA-3492-11A-01D-1408-10 g.chr16:2283540_2283541insG c.1158_1159insG c.(1159-1161)gggfs p.G387fs COAD 16 2283577 2283577 + Missense_Mutation SNP G G A TCGA-CM-4743-01A-01D-1719-10 TCGA-CM-4743-10A-01D-1719-10 g.chr16:2283577G>A c.1195G>A c.(1195-1197)Ggg>Agg p.G399R COAD 16 2283955 2283955 + Missense_Mutation SNP G G A TCGA-AD-6889-01A-11D-1924-10 TCGA-AD-6889-10A-01D-1924-10 g.chr16:2283955G>A c.1339G>A c.(1339-1341)Gca>Aca p.A447T COAD 16 2284270 2284270 + Missense_Mutation SNP C C T TCGA-CM-6162-01A-11D-1650-10 TCGA-CM-6162-10A-01D-1650-10 g.chr16:2284270C>T c.1474C>T c.(1474-1476)Cgc>Tgc p.R492C COAD 16 2284863 2284863 + Missense_Mutation SNP G G A TCGA-CM-6674-01A-11D-1835-10 TCGA-CM-6674-10A-01D-1835-10 g.chr16:2284863G>A c.1796G>A c.(1795-1797)gGc>gAc p.G599D COAD 16 2284933 2284933 + Silent SNP G G A TCGA-A6-5661-01A-01D-1650-10 TCGA-A6-5661-10A-01D-1650-10 g.chr16:2284933G>A c.1866G>A c.(1864-1866)acG>acA p.T622T COAD 16 2285268 2285268 + Missense_Mutation SNP G G A TCGA-AD-6895-01A-11D-1924-10 TCGA-AD-6895-10A-01D-1924-10 g.chr16:2285268G>A c.2050G>A c.(2050-2052)Gcc>Acc p.A684T COAD 16 2285362 2285362 + Frame_Shift_Del DEL C C - TCGA-AU-6004-01A-11D-1719-10 TCGA-AU-6004-10A-01D-1719-10 g.chr16:2285362delC c.2144delC c.(2143-2145)accfs p.T715fs COADREAD 16 2279661 2279661 + Missense_Mutation SNP G G A TCGA-AD-6895-01A-11D-1924-10 TCGA-AD-6895-10A-01D-1924-10 g.chr16:2279661G>A c.400G>A c.(400-402)Gca>Aca p.A134T COADREAD 16 2282275 2282275 + Silent SNP C C T TCGA-A6-6781-01A-22D-1924-10 TCGA-A6-6781-10A-01D-1924-10 g.chr16:2282275C>T c.519C>T c.(517-519)ctC>ctT p.L173L COADREAD 16 2282575 2282575 + Missense_Mutation SNP C C T TCGA-AZ-4323-01A-21D-1835-10 TCGA-AZ-4323-10A-01D-1835-10 g.chr16:2282575C>T c.728C>T c.(727-729)aCg>aTg p.T243M COADREAD 16 2282783 2282783 + Missense_Mutation SNP T T C TCGA-AH-6643-01A-11D-1826-10 TCGA-AH-6643-11A-01D-1826-10 g.chr16:2282783T>C c.757T>C c.(757-759)Tgt>Cgt p.C253R COADREAD 16 2283133 2283133 + Silent SNP C C T TCGA-AA-3663-01A-01D-1719-10 TCGA-AA-3663-11A-01D-1719-10 g.chr16:2283133C>T c.1005C>T c.(1003-1005)gtC>gtT p.V335V COADREAD 16 2283533 2283533 + Missense_Mutation SNP G G A TCGA-DM-A28G-01A-11D-A16V-10 TCGA-DM-A28G-10A-01D-A16V-10 g.chr16:2283533G>A c.1151G>A c.(1150-1152)cGc>cAc p.R384H COADREAD 16 2283540 2283541 + Frame_Shift_Ins INS - - G TCGA-AA-3492-01A-01D-1408-10 TCGA-AA-3492-11A-01D-1408-10 g.chr16:2283540_2283541insG c.1158_1159insG c.(1159-1161)gggfs p.G387fs COADREAD 16 2283577 2283577 + Missense_Mutation SNP G G A TCGA-CM-4743-01A-01D-1719-10 TCGA-CM-4743-10A-01D-1719-10 g.chr16:2283577G>A c.1195G>A c.(1195-1197)Ggg>Agg p.G399R COADREAD 16 2283955 2283955 + Missense_Mutation SNP G G A TCGA-AD-6889-01A-11D-1924-10 TCGA-AD-6889-10A-01D-1924-10 g.chr16:2283955G>A c.1339G>A c.(1339-1341)Gca>Aca p.A447T COADREAD 16 2284270 2284270 + Missense_Mutation SNP C C T TCGA-CM-6162-01A-11D-1650-10 TCGA-CM-6162-10A-01D-1650-10 g.chr16:2284270C>T c.1474C>T c.(1474-1476)Cgc>Tgc p.R492C COADREAD 16 2284863 2284863 + Missense_Mutation SNP G G A TCGA-CM-6674-01A-11D-1835-10 TCGA-CM-6674-10A-01D-1835-10 g.chr16:2284863G>A c.1796G>A c.(1795-1797)gGc>gAc p.G599D COADREAD 16 2284933 2284933 + Silent SNP G G A TCGA-A6-5661-01A-01D-1650-10 TCGA-A6-5661-10A-01D-1650-10 g.chr16:2284933G>A c.1866G>A c.(1864-1866)acG>acA p.T622T COADREAD 16 2285268 2285268 + Missense_Mutation SNP G G A TCGA-AD-6895-01A-11D-1924-10 TCGA-AD-6895-10A-01D-1924-10 g.chr16:2285268G>A c.2050G>A c.(2050-2052)Gcc>Acc p.A684T COADREAD 16 2285362 2285362 + Frame_Shift_Del DEL C C - TCGA-AU-6004-01A-11D-1719-10 TCGA-AU-6004-10A-01D-1719-10 g.chr16:2285362delC c.2144delC c.(2143-2145)accfs p.T715fs DLBC 16 2273676 2273676 + Missense_Mutation SNP C C A TCGA-G8-6324-01A-11D-2210-10 TCGA-G8-6324-10A-01D-2210-10 g.chr16:2273676C>A c.62C>A c.(61-63)gCc>gAc p.A21D GBMLGG 16 2278405 2278405 + Missense_Mutation SNP C C G TCGA-FG-A6IZ-01A-11D-A31L-08 TCGA-FG-A6IZ-10A-01D-A31J-08 g.chr16:2278405C>G c.190C>G c.(190-192)Cag>Gag p.Q64E GBMLGG 16 2279638 2279638 + Missense_Mutation SNP C C T TCGA-DU-6400-01A-12D-1705-08 TCGA-DU-6400-10A-01D-1705-08 g.chr16:2279638C>T c.377C>T c.(376-378)tCt>tTt p.S126F GBMLGG 16 2282496 2282496 + Missense_Mutation SNP C C T TCGA-FG-6692-01A-11D-1893-08 TCGA-FG-6692-10A-01D-1893-08 g.chr16:2282496C>T c.649C>T c.(649-651)Cgc>Tgc p.R217C GBMLGG 16 2284592 2284592 + Silent SNP G G A TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr16:2284592G>A c.1602G>A c.(1600-1602)caG>caA p.Q534Q GBMLGG 16 2285119 2285119 + Missense_Mutation SNP A A G TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr16:2285119A>G c.1973A>G c.(1972-1974)gAg>gGg p.E658G HNSC 16 2273689 2273689 + Silent SNP G G A TCGA-CN-6995-01A-31D-2012-08 TCGA-CN-6995-10A-01D-2013-08 g.chr16:2273689G>A c.75G>A c.(73-75)gcG>gcA p.A25A HNSC 16 2273707 2273707 + Silent SNP G G A TCGA-CV-6441-01A-11D-1683-08 TCGA-CV-6441-11A-01D-1683-08 g.chr16:2273707G>A c.93G>A c.(91-93)gcG>gcA p.A31A HNSC 16 2282198 2282198 + Missense_Mutation SNP G G A TCGA-CN-A63U-01A-11D-A30E-08 TCGA-CN-A63U-10A-01D-A30H-08 g.chr16:2282198G>A c.442G>A c.(442-444)Gtg>Atg p.V148M HNSC 16 2282237 2282237 + Missense_Mutation SNP G G A TCGA-D6-6826-01A-11D-1912-08 TCGA-D6-6826-10A-01D-1912-08 g.chr16:2282237G>A c.481G>A c.(481-483)Gag>Aag p.E161K HNSC 16 2283182 2283182 + Nonsense_Mutation SNP G G T TCGA-CN-5369-01A-01D-1434-08 TCGA-CN-5369-10A-01D-1434-08 g.chr16:2283182G>T c.1054G>T c.(1054-1056)Gag>Tag p.E352* HNSC 16 2285271 2285271 + Missense_Mutation SNP G G A TCGA-F7-A624-01A-22D-A30E-08 TCGA-F7-A624-10A-01D-A30H-08 g.chr16:2285271G>A c.2053G>A c.(2053-2055)Ggc>Agc p.G685S KICH 16 2282184 2282184 + Missense_Mutation SNP T T C TCGA-KN-8428-01A-11D-2310-10 TCGA-KN-8428-11A-01D-2311-10 g.chr16:2282184T>C c.428T>C c.(427-429)aTc>aCc p.I143T KIPAN 16 2282184 2282184 + Missense_Mutation SNP T T C TCGA-KN-8428-01A-11D-2310-10 TCGA-KN-8428-11A-01D-2311-10 g.chr16:2282184T>C c.428T>C c.(427-429)aTc>aCc p.I143T KIPAN 16 2285002 2285002 + Splice_Site SNP G G T TCGA-HE-A5NF-01A-11D-A26P-10 TCGA-HE-A5NF-10A-01D-A26P-10 g.chr16:2285002G>T c.1935G>T c.(1933-1935)gaG>gaT p.E645D KIRP 16 2285002 2285002 + Splice_Site SNP G G T TCGA-HE-A5NF-01A-11D-A26P-10 TCGA-HE-A5NF-10A-01D-A26P-10 g.chr16:2285002G>T c.1935G>T c.(1933-1935)gaG>gaT p.E645D LGG 16 2278405 2278405 + Missense_Mutation SNP C C G TCGA-FG-A6IZ-01A-11D-A31L-08 TCGA-FG-A6IZ-10A-01D-A31J-08 g.chr16:2278405C>G c.190C>G c.(190-192)Cag>Gag p.Q64E LGG 16 2279638 2279638 + Missense_Mutation SNP C C T TCGA-DU-6400-01A-12D-1705-08 TCGA-DU-6400-10A-01D-1705-08 g.chr16:2279638C>T c.377C>T c.(376-378)tCt>tTt p.S126F LGG 16 2282496 2282496 + Missense_Mutation SNP C C T TCGA-FG-6692-01A-11D-1893-08 TCGA-FG-6692-10A-01D-1893-08 g.chr16:2282496C>T c.649C>T c.(649-651)Cgc>Tgc p.R217C LGG 16 2284592 2284592 + Silent SNP G G A TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr16:2284592G>A c.1602G>A c.(1600-1602)caG>caA p.Q534Q LGG 16 2285119 2285119 + Missense_Mutation SNP A A G TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr16:2285119A>G c.1973A>G c.(1972-1974)gAg>gGg p.E658G LIHC 16 2282755 2282755 + Splice_Site SNP A A C TCGA-UB-A7MB-01A-11D-A33Q-10 TCGA-UB-A7MB-10A-01D-A33Q-10 g.chr16:2282755A>C c.e6-1 LUAD 16 2278460 2278460 + Missense_Mutation SNP G G T TCGA-38-4629-01A-02D-1265-08 TCGA-38-4629-11A-01D-1265-08 g.chr16:2278460G>T c.245G>T c.(244-246)tGc>tTc p.C82F LUAD 16 2282276 2282276 + Missense_Mutation SNP G G T TCGA-55-7727-01A-11D-2167-08 TCGA-55-7727-10A-01D-2167-08 g.chr16:2282276G>T c.520G>T c.(520-522)Gca>Tca p.A174S LUAD 16 2284322 2284322 + Missense_Mutation SNP A A T TCGA-78-7155-01A-11D-2036-08 TCGA-78-7155-10A-01D-2036-08 g.chr16:2284322A>T c.1526A>T c.(1525-1527)cAc>cTc p.H509L LUAD 16 2285348 2285348 + Silent SNP C C T TCGA-69-7979-01A-11D-2184-08 TCGA-69-7979-10A-01D-2184-08 g.chr16:2285348C>T c.2130C>T c.(2128-2130)acC>acT p.T710T LUAD 16 2285496 2285496 + Missense_Mutation SNP G G A TCGA-38-4625-01A-01D-1553-08 TCGA-38-4625-11A-01D-1553-08 g.chr16:2285496G>A c.2278G>A c.(2278-2280)Gag>Aag p.E760K LUSC 16 2278471 2278471 + Missense_Mutation SNP C C T TCGA-34-5232-01A-21D-1817-08 TCGA-34-5232-10A-01D-1817-08 g.chr16:2278471C>T c.256C>T c.(256-258)Cct>Tct p.P86S LUSC 16 2279622 2279622 + Missense_Mutation SNP G G C TCGA-51-4080-01A-01D-1458-08 TCGA-51-4080-11A-01D-1458-08 g.chr16:2279622G>C c.361G>C c.(361-363)Gtg>Ctg p.V121L LUSC 16 2282275 2282275 + Silent SNP C C G TCGA-66-2771-01A-01D-0983-08 TCGA-66-2771-11A-01D-0983-08 g.chr16:2282275C>G c.519C>G c.(517-519)ctC>ctG p.L173L LUSC 16 2282359 2282359 + Missense_Mutation SNP C C G TCGA-22-5477-01A-01D-1632-08 TCGA-22-5477-11A-11D-1632-08 g.chr16:2282359C>G c.603C>G c.(601-603)ttC>ttG p.F201L OV 16 2282783 2282783 + Missense_Mutation SNP T T G TCGA-13-1482-01A-01W-0549-09 TCGA-13-1482-10A-01W-0549-09 g.chr16:2282783T>G c.757T>G c.(757-759)Tgt>Ggt p.C253G PAAD 16 2279622 2279622 + Missense_Mutation SNP G G A TCGA-IB-7651-01A-11D-2154-08 TCGA-IB-7651-10A-01D-2154-08 g.chr16:2279622G>A c.361G>A c.(361-363)Gtg>Atg p.V121M PAAD 16 2284179 2284196 + In_Frame_Del DEL GCCGTTCGCCTGCGCGCA GCCGTTCGCCTGCGCGCA - TCGA-IB-7652-01A-11D-2154-08 TCGA-IB-7652-10A-01D-2154-08 g.chr16:2284179_2284196delGCCGTTCGCCTGCGCGCA c.1383_1400delGCCGTTCGCCTGCGCGCA c.(1381-1401)aggccgttcgcctgcgcgcag>agg p.PFACAQ462del PRAD 16 2284279 2284279 + Missense_Mutation SNP G G A TCGA-XK-AAIW-01A-11D-A41K-08 TCGA-XK-AAIW-10A-01D-A41N-08 g.chr16:2284279G>A c.1483G>A c.(1483-1485)Gac>Aac p.D495N PRAD 16 2284613 2284613 + Silent SNP C C T TCGA-J9-A8CL-01A-11D-A34U-08 TCGA-J9-A8CL-10A-01D-A34X-08 g.chr16:2284613C>T c.1623C>T c.(1621-1623)caC>caT p.H541H PRAD 16 2285489 2285489 + Missense_Mutation SNP G G T TCGA-XK-AAIW-01A-11D-A41K-08 TCGA-XK-AAIW-10A-01D-A41N-08 g.chr16:2285489G>T c.2271G>T c.(2269-2271)gaG>gaT p.E757D READ 16 2282783 2282783 + Missense_Mutation SNP T T C TCGA-AH-6643-01A-11D-1826-10 TCGA-AH-6643-11A-01D-1826-10 g.chr16:2282783T>C c.757T>C c.(757-759)Tgt>Cgt p.C253R SARC 16 2284933 2284933 + Silent SNP G G A TCGA-DX-AB32-01A-11D-A417-09 TCGA-DX-AB32-10A-01D-A41A-09 g.chr16:2284933G>A c.1866G>A c.(1864-1866)acG>acA p.T622T SKCM 16 2282530 2282530 + Missense_Mutation SNP C C T TCGA-EE-A17X-06A-11D-A197-08 TCGA-EE-A17X-10A-01D-A199-08 g.chr16:2282530C>T c.683C>T c.(682-684)tCc>tTc p.S228F SKCM 16 2283125 2283125 + Missense_Mutation SNP C C T TCGA-D3-A51J-06A-11D-A25O-08 TCGA-D3-A51J-10A-01D-A25O-08 g.chr16:2283125C>T c.997C>T c.(997-999)Cac>Tac p.H333Y SKCM 16 2283156 2283156 + Missense_Mutation SNP C C T TCGA-ER-A19M-06A-61D-A23B-08 TCGA-ER-A19M-10A-01D-A23B-08 g.chr16:2283156C>T c.1028C>T c.(1027-1029)tCc>tTc p.S343F SKCM 16 2283184 2283184 + Splice_Site SNP G G A TCGA-D3-A2JP-06A-11D-A19A-08 TCGA-D3-A2JP-10A-01D-A19A-08 g.chr16:2283184G>A c.1056G>A c.(1054-1056)gaG>gaA p.E352E SKCM 16 2284180 2284180 + Missense_Mutation SNP C C T TCGA-D9-A1JW-06A-11D-A19A-08 TCGA-D9-A1JW-10A-01D-A19A-08 g.chr16:2284180C>T c.1384C>T c.(1384-1386)Ccg>Tcg p.P462S SKCM 16 2284185 2284185 + Silent SNP C C T TCGA-ER-A193-06A-12D-A197-08 TCGA-ER-A193-10A-01D-A199-08 g.chr16:2284185C>T c.1389C>T c.(1387-1389)ttC>ttT p.F463F SKCM 16 2284186 2284186 + Missense_Mutation SNP G G C TCGA-FS-A1ZK-06A-11D-A197-08 TCGA-FS-A1ZK-10A-01D-A199-08 g.chr16:2284186G>C c.1390G>C c.(1390-1392)Gcc>Ccc p.A464P SKCM 16 2284258 2284258 + Missense_Mutation SNP G G A TCGA-DA-A1IA-06A-11D-A196-08 TCGA-DA-A1IA-10A-01D-A198-08 g.chr16:2284258G>A c.1462G>A c.(1462-1464)Gag>Aag p.E488K SKCM 16 2285285 2285285 + Silent SNP C C T TCGA-EE-A20C-06A-11D-A196-08 TCGA-EE-A20C-10A-01D-A198-08 g.chr16:2285285C>T c.2067C>T c.(2065-2067)atC>atT p.I689I SKCM 16 2285568 2285568 + Missense_Mutation SNP G G A TCGA-FS-A1ZW-06A-12D-A197-08 TCGA-FS-A1ZW-10A-01D-A199-08 g.chr16:2285568G>A c.2350G>A c.(2350-2352)Gtc>Atc p.V784I

Mutation - ICGC Project Code Chromosome Chromosome Start Chromosome End Mutation Type Mutated from Allele Mutated to Allele Consequence Type AA Mutation CDS Mutation BLCA-CN 16 2283492 2283492 single base substitution G A downstream_gene_variant BLCA-CN 16 2283492 2283492 single base substitution G A exon_variant BLCA-CN 16 2283492 2283492 single base substitution G A synonymous_variant L370L 1110G>A BLCA-CN 16 2283492 2283492 single base substitution G A upstream_gene_variant BLCA-CN 16 2284293 2284293 single base substitution C G downstream_gene_variant BLCA-CN 16 2284293 2284293 single base substitution C G exon_variant BLCA-CN 16 2284293 2284293 single base substitution C G intron_variant BLCA-CN 16 2284293 2284293 single base substitution C G synonymous_variant L499L 1497C>G BLCA-CN 16 2284293 2284293 single base substitution C G upstream_gene_variant BLCA-CN 16 2285098 2285098 single base substitution C T downstream_gene_variant BLCA-CN 16 2285098 2285098 single base substitution C T exon_variant BLCA-CN 16 2285098 2285098 single base substitution C T missense_variant A474V 1421C>T BLCA-CN 16 2285098 2285098 single base substitution C T missense_variant A651V 1952C>T BLCA-CN 16 2285098 2285098 single base substitution C T missense_variant R634W 1900C>T BLCA-US 16 2286829 2286829 single base substitution C T downstream_gene_variant BRCA-EU 16 2269546 2269546 single base substitution G A upstream_gene_variant BRCA-EU 16 2270120 2270120 single base substitution C T upstream_gene_variant BRCA-EU 16 2270961 2270961 single base substitution C G upstream_gene_variant BRCA-EU 16 2271405 2271405 insertion of <=200bp - T upstream_gene_variant BRCA-EU 16 2271502 2271502 single base substitution C T upstream_gene_variant BRCA-EU 16 2272759 2272759 single base substitution C T upstream_gene_variant BRCA-EU 16 2273894 2273894 single base substitution C G intron_variant BRCA-EU 16 2273894 2273894 single base substitution C G missense_variant L19V 55C>G BRCA-EU 16 2273894 2273894 single base substitution C G upstream_gene_variant BRCA-EU 16 2274001 2274001 single base substitution A G intron_variant BRCA-EU 16 2274001 2274001 single base substitution A G upstream_gene_variant BRCA-EU 16 2274557 2274557 single base substitution G C intron_variant BRCA-EU 16 2274557 2274557 single base substitution G C upstream_gene_variant BRCA-EU 16 2274726 2274726 single base substitution G A intron_variant BRCA-EU 16 2274726 2274726 single base substitution G A upstream_gene_variant BRCA-EU 16 2274944 2274944 single base substitution T C intron_variant BRCA-EU 16 2274944 2274944 single base substitution T C upstream_gene_variant BRCA-EU 16 2274975 2274975 single base substitution A T intron_variant BRCA-EU 16 2274975 2274975 single base substitution A T upstream_gene_variant BRCA-EU 16 2275324 2275324 single base substitution C G intron_variant BRCA-EU 16 2275324 2275324 single base substitution C G upstream_gene_variant BRCA-EU 16 2276947 2276947 single base substitution C G intron_variant BRCA-EU 16 2276947 2276947 single base substitution C G upstream_gene_variant BRCA-EU 16 2277417 2277417 single base substitution G T intron_variant BRCA-EU 16 2277417 2277417 single base substitution G T upstream_gene_variant BRCA-EU 16 2279425 2279425 single base substitution C T intron_variant BRCA-EU 16 2279425 2279425 single base substitution C T upstream_gene_variant BRCA-EU 16 2280068 2280068 single base substitution G A exon_variant BRCA-EU 16 2280068 2280068 single base substitution G A intron_variant BRCA-EU 16 2280068 2280068 single base substitution G A upstream_gene_variant BRCA-EU 16 2281021 2281021 single base substitution C G exon_variant BRCA-EU 16 2281021 2281021 single base substitution C G intron_variant BRCA-EU 16 2281021 2281021 single base substitution C G upstream_gene_variant BRCA-EU 16 2281428 2281428 single base substitution T G exon_variant BRCA-EU 16 2281428 2281428 single base substitution T G intron_variant BRCA-EU 16 2281428 2281428 single base substitution T G upstream_gene_variant BRCA-EU 16 2281457 2281457 single base substitution C G exon_variant BRCA-EU 16 2281457 2281457 single base substitution C G intron_variant BRCA-EU 16 2281457 2281457 single base substitution C G upstream_gene_variant BRCA-EU 16 2282468 2282468 single base substitution C T 3_prime_UTR_variant BRCA-EU 16 2282468 2282468 single base substitution C T exon_variant BRCA-EU 16 2282468 2282468 single base substitution C T synonymous_variant L185L 555C>T BRCA-EU 16 2282468 2282468 single base substitution C T synonymous_variant L207L 621C>T BRCA-EU 16 2282468 2282468 single base substitution C T upstream_gene_variant BRCA-EU 16 2282857 2282857 single base substitution C G downstream_gene_variant BRCA-EU 16 2282857 2282857 single base substitution C G exon_variant BRCA-EU 16 2282857 2282857 single base substitution C G missense_variant I255M 765C>G BRCA-EU 16 2282857 2282857 single base substitution C G missense_variant I277M 831C>G BRCA-EU 16 2282857 2282857 single base substitution C G upstream_gene_variant BRCA-EU 16 2283718 2283718 single base substitution C A downstream_gene_variant BRCA-EU 16 2283718 2283718 single base substitution C A exon_variant BRCA-EU 16 2283718 2283718 single base substitution C A intron_variant BRCA-EU 16 2283718 2283718 single base substitution C A upstream_gene_variant BRCA-EU 16 2284398 2284398 single base substitution C G downstream_gene_variant BRCA-EU 16 2284398 2284398 single base substitution C G exon_variant BRCA-EU 16 2284398 2284398 single base substitution C G intron_variant BRCA-EU 16 2284398 2284398 single base substitution C G upstream_gene_variant BRCA-EU 16 2284492 2284492 single base substitution G A downstream_gene_variant BRCA-EU 16 2284492 2284492 single base substitution G A exon_variant BRCA-EU 16 2284492 2284492 single base substitution G A intron_variant BRCA-EU 16 2284492 2284492 single base substitution G A upstream_gene_variant BRCA-EU 16 2284677 2284677 single base substitution G A downstream_gene_variant BRCA-EU 16 2284677 2284677 single base substitution G A exon_variant BRCA-EU 16 2284677 2284677 single base substitution G A missense_variant V386M 1156G>A BRCA-EU 16 2284677 2284677 single base substitution G A missense_variant V563M 1687G>A BRCA-EU 16 2284896 2284896 single base substitution C A downstream_gene_variant BRCA-EU 16 2284896 2284896 single base substitution C A exon_variant BRCA-EU 16 2284896 2284896 single base substitution C A missense_variant S433Y 1298C>A BRCA-EU 16 2284896 2284896 single base substitution C A missense_variant S610Y 1829C>A BRCA-EU 16 2284942 2284942 single base substitution G A downstream_gene_variant BRCA-EU 16 2284942 2284942 single base substitution G A exon_variant BRCA-EU 16 2284942 2284942 single base substitution G A synonymous_variant P448P 1344G>A BRCA-EU 16 2284942 2284942 single base substitution G A synonymous_variant P625P 1875G>A BRCA-EU 16 2285168 2285168 single base substitution C T downstream_gene_variant BRCA-EU 16 2285168 2285168 single base substitution C T exon_variant BRCA-EU 16 2285168 2285168 single base substitution C T intron_variant BRCA-EU 16 2285627 2285627 single base substitution G A 3_prime_UTR_variant BRCA-EU 16 2285627 2285627 single base substitution G A downstream_gene_variant BRCA-EU 16 2285627 2285627 single base substitution G A exon_variant BRCA-EU 16 2287030 2287030 single base substitution C T downstream_gene_variant BRCA-EU 16 2287327 2287327 single base substitution G A downstream_gene_variant BRCA-EU 16 2287438 2287438 single base substitution C T downstream_gene_variant BRCA-EU 16 2288954 2288954 single base substitution G A downstream_gene_variant BRCA-EU 16 2290079 2290079 single base substitution G A downstream_gene_variant BRCA-EU 16 2290338 2290338 single base substitution G C downstream_gene_variant BRCA-FR 16 2272759 2272759 single base substitution C T upstream_gene_variant BRCA-FR 16 2273162 2273162 single base substitution C T upstream_gene_variant BRCA-FR 16 2273894 2273894 single base substitution C G intron_variant BRCA-FR 16 2273894 2273894 single base substitution C G missense_variant L19V 55C>G BRCA-FR 16 2273894 2273894 single base substitution C G upstream_gene_variant BRCA-FR 16 2279425 2279425 single base substitution C T intron_variant BRCA-FR 16 2279425 2279425 single base substitution C T upstream_gene_variant BRCA-FR 16 2281021 2281021 single base substitution C G exon_variant BRCA-FR 16 2281021 2281021 single base substitution C G intron_variant BRCA-FR 16 2281021 2281021 single base substitution C G upstream_gene_variant BRCA-FR 16 2281457 2281457 single base substitution C G exon_variant BRCA-FR 16 2281457 2281457 single base substitution C G intron_variant BRCA-FR 16 2281457 2281457 single base substitution C G upstream_gene_variant BRCA-FR 16 2281665 2281665 single base substitution C A exon_variant BRCA-FR 16 2281665 2281665 single base substitution C A intron_variant BRCA-FR 16 2281665 2281665 single base substitution C A upstream_gene_variant BRCA-FR 16 2282468 2282468 single base substitution C T 3_prime_UTR_variant BRCA-FR 16 2282468 2282468 single base substitution C T exon_variant BRCA-FR 16 2282468 2282468 single base substitution C T synonymous_variant L185L 555C>T BRCA-FR 16 2282468 2282468 single base substitution C T synonymous_variant L207L 621C>T BRCA-FR 16 2282468 2282468 single base substitution C T upstream_gene_variant BRCA-FR 16 2282857 2282857 single base substitution C G downstream_gene_variant BRCA-FR 16 2282857 2282857 single base substitution C G exon_variant BRCA-FR 16 2282857 2282857 single base substitution C G missense_variant I255M 765C>G BRCA-FR 16 2282857 2282857 single base substitution C G missense_variant I277M 831C>G BRCA-FR 16 2282857 2282857 single base substitution C G upstream_gene_variant BRCA-FR 16 2287438 2287438 single base substitution C T downstream_gene_variant BRCA-FR 16 2288237 2288237 single base substitution C G downstream_gene_variant BRCA-KR 16 2284918 2284918 single base substitution C G downstream_gene_variant BRCA-KR 16 2284918 2284918 single base substitution C G exon_variant BRCA-KR 16 2284918 2284918 single base substitution C G synonymous_variant A440A 1320C>G BRCA-KR 16 2284918 2284918 single base substitution C G synonymous_variant A617A 1851C>G BRCA-US 16 2282221 2282221 single base substitution A G exon_variant BRCA-US 16 2282221 2282221 single base substitution A G synonymous_variant G133G 399A>G BRCA-US 16 2282221 2282221 single base substitution A G synonymous_variant G155G 465A>G BRCA-US 16 2282221 2282221 single base substitution A G upstream_gene_variant BRCA-US 16 2283116 2283116 single base substitution A G downstream_gene_variant BRCA-US 16 2283116 2283116 single base substitution A G exon_variant BRCA-US 16 2283116 2283116 single base substitution A G missense_variant T330A 988A>G BRCA-US 16 2283116 2283116 single base substitution A G upstream_gene_variant BRCA-US 16 2283890 2283890 single base substitution C T downstream_gene_variant BRCA-US 16 2283890 2283890 single base substitution C T exon_variant BRCA-US 16 2283890 2283890 single base substitution C T intron_variant BRCA-US 16 2283890 2283890 single base substitution C T missense_variant A425V 1274C>T BRCA-US 16 2283890 2283890 single base substitution C T upstream_gene_variant BRCA-US 16 2284337 2284337 single base substitution C T downstream_gene_variant BRCA-US 16 2284337 2284337 single base substitution C T exon_variant BRCA-US 16 2284337 2284337 single base substitution C T intron_variant BRCA-US 16 2284337 2284337 single base substitution C T missense_variant S514L 1541C>T BRCA-US 16 2284337 2284337 single base substitution C T upstream_gene_variant BRCA-US 16 2285081 2285081 single base substitution G A downstream_gene_variant BRCA-US 16 2285081 2285081 single base substitution G A exon_variant BRCA-US 16 2285081 2285081 single base substitution G A splice_acceptor_variant BRCA-US 16 2287303 2287303 single base substitution G A downstream_gene_variant BRCA-US 16 2288404 2288404 single base substitution C G downstream_gene_variant BRCA-US 16 2290147 2290147 single base substitution C G downstream_gene_variant BTCA-JP 16 2282438 2282438 single base substitution G A intron_variant BTCA-JP 16 2282438 2282438 single base substitution G A upstream_gene_variant BTCA-JP 16 2284703 2284703 single base substitution C T downstream_gene_variant BTCA-JP 16 2284703 2284703 single base substitution C T exon_variant BTCA-JP 16 2284703 2284703 single base substitution C T synonymous_variant G394G 1182C>T BTCA-JP 16 2284703 2284703 single base substitution C T synonymous_variant G571G 1713C>T BTCA-JP 16 2285231 2285231 single base substitution C A downstream_gene_variant BTCA-JP 16 2285231 2285231 single base substitution C A exon_variant BTCA-JP 16 2285231 2285231 single base substitution C A stop_gained S654* 1961C>A BTCA-JP 16 2285231 2285231 single base substitution C A synonymous_variant I494I 1482C>A BTCA-JP 16 2285231 2285231 single base substitution C A synonymous_variant I671I 2013C>A BTCA-JP 16 2285255 2285255 single base substitution G A 3_prime_UTR_variant BTCA-JP 16 2285255 2285255 single base substitution G A downstream_gene_variant BTCA-JP 16 2285255 2285255 single base substitution G A exon_variant BTCA-JP 16 2285255 2285255 single base substitution G A synonymous_variant V502V 1506G>A BTCA-JP 16 2285255 2285255 single base substitution G A synonymous_variant V679V 2037G>A BTCA-JP 16 2287978 2287978 single base substitution G A downstream_gene_variant CESC-US 16 2283533 2283533 single base substitution G C downstream_gene_variant CESC-US 16 2283533 2283533 single base substitution G C exon_variant CESC-US 16 2283533 2283533 single base substitution G C intron_variant CESC-US 16 2283533 2283533 single base substitution G C missense_variant R384P 1151G>C CESC-US 16 2283533 2283533 single base substitution G C upstream_gene_variant CESC-US 16 2285568 2285568 single base substitution G A 3_prime_UTR_variant CESC-US 16 2285568 2285568 single base substitution G A downstream_gene_variant CESC-US 16 2285568 2285568 single base substitution G A exon_variant CESC-US 16 2285568 2285568 single base substitution G A missense_variant V607I 1819G>A CESC-US 16 2285568 2285568 single base substitution G A missense_variant V784I 2350G>A COAD-US 16 2278400 2278400 single base substitution G A exon_variant COAD-US 16 2278400 2278400 single base substitution G A missense_variant R40H 119G>A COAD-US 16 2278400 2278400 single base substitution G A missense_variant R62H 185G>A COAD-US 16 2278400 2278400 single base substitution G A upstream_gene_variant COAD-US 16 2279661 2279661 single base substitution G A exon_variant COAD-US 16 2279661 2279661 single base substitution G A missense_variant A112T 334G>A COAD-US 16 2279661 2279661 single base substitution G A missense_variant A134T 400G>A COAD-US 16 2279661 2279661 single base substitution G A upstream_gene_variant COAD-US 16 2282275 2282275 single base substitution C T exon_variant COAD-US 16 2282275 2282275 single base substitution C T synonymous_variant L151L 453C>T COAD-US 16 2282275 2282275 single base substitution C T synonymous_variant L173L 519C>T COAD-US 16 2282275 2282275 single base substitution C T upstream_gene_variant COAD-US 16 2282575 2282575 single base substitution C T missense_variant T221M 662C>T COAD-US 16 2282575 2282575 single base substitution C T missense_variant T243M 728C>T COAD-US 16 2282575 2282575 single base substitution C T splice_region_variant COAD-US 16 2282575 2282575 single base substitution C T upstream_gene_variant COAD-US 16 2283133 2283133 single base substitution C T downstream_gene_variant COAD-US 16 2283133 2283133 single base substitution C T exon_variant COAD-US 16 2283133 2283133 single base substitution C T synonymous_variant V335V 1005C>T COAD-US 16 2283133 2283133 single base substitution C T upstream_gene_variant COAD-US 16 2283471 2283471 single base substitution C T downstream_gene_variant COAD-US 16 2283471 2283471 single base substitution C T exon_variant COAD-US 16 2283471 2283471 single base substitution C T synonymous_variant S363S 1089C>T COAD-US 16 2283471 2283471 single base substitution C T upstream_gene_variant COAD-US 16 2283540 2283540 insertion of <=200bp - G downstream_gene_variant COAD-US 16 2283540 2283540 insertion of <=200bp - G exon_variant COAD-US 16 2283540 2283540 insertion of <=200bp - G frameshift_variant A386A? COAD-US 16 2283540 2283540 insertion of <=200bp - G intron_variant COAD-US 16 2283540 2283540 insertion of <=200bp - G upstream_gene_variant COAD-US 16 2283577 2283577 single base substitution G A downstream_gene_variant COAD-US 16 2283577 2283577 single base substitution G A exon_variant COAD-US 16 2283577 2283577 single base substitution G A intron_variant COAD-US 16 2283577 2283577 single base substitution G A missense_variant G399R 1195G>A COAD-US 16 2283577 2283577 single base substitution G A upstream_gene_variant COAD-US 16 2283955 2283955 single base substitution G A downstream_gene_variant COAD-US 16 2283955 2283955 single base substitution G A exon_variant COAD-US 16 2283955 2283955 single base substitution G A intron_variant COAD-US 16 2283955 2283955 single base substitution G A missense_variant A447T 1339G>A COAD-US 16 2283955 2283955 single base substitution G A upstream_gene_variant COAD-US 16 2284270 2284270 single base substitution C T downstream_gene_variant COAD-US 16 2284270 2284270 single base substitution C T exon_variant COAD-US 16 2284270 2284270 single base substitution C T intron_variant COAD-US 16 2284270 2284270 single base substitution C T missense_variant R492C 1474C>T COAD-US 16 2284270 2284270 single base substitution C T upstream_gene_variant COAD-US 16 2284732 2284732 single base substitution G A downstream_gene_variant COAD-US 16 2284732 2284732 single base substitution G A exon_variant COAD-US 16 2284732 2284732 single base substitution G A missense_variant G404D 1211G>A COAD-US 16 2284732 2284732 single base substitution G A missense_variant G581D 1742G>A COAD-US 16 2284863 2284863 single base substitution G A downstream_gene_variant COAD-US 16 2284863 2284863 single base substitution G A exon_variant COAD-US 16 2284863 2284863 single base substitution G A missense_variant G422D 1265G>A COAD-US 16 2284863 2284863 single base substitution G A missense_variant G599D 1796G>A COAD-US 16 2284933 2284933 single base substitution G A downstream_gene_variant COAD-US 16 2284933 2284933 single base substitution G A exon_variant COAD-US 16 2284933 2284933 single base substitution G A synonymous_variant T445T 1335G>A COAD-US 16 2284933 2284933 single base substitution G A synonymous_variant T622T 1866G>A COAD-US 16 2285268 2285268 single base substitution G A 3_prime_UTR_variant COAD-US 16 2285268 2285268 single base substitution G A downstream_gene_variant COAD-US 16 2285268 2285268 single base substitution G A exon_variant COAD-US 16 2285268 2285268 single base substitution G A missense_variant A507T 1519G>A COAD-US 16 2285268 2285268 single base substitution G A missense_variant A684T 2050G>A COAD-US 16 2285357 2285357 single base substitution C T 3_prime_UTR_variant COAD-US 16 2285357 2285357 single base substitution C T downstream_gene_variant COAD-US 16 2285357 2285357 single base substitution C T exon_variant COAD-US 16 2285357 2285357 single base substitution C T synonymous_variant I536I 1608C>T COAD-US 16 2285357 2285357 single base substitution C T synonymous_variant I713I 2139C>T COAD-US 16 2285362 2285362 deletion of <=200bp C - 3_prime_UTR_variant COAD-US 16 2285362 2285362 deletion of <=200bp C - downstream_gene_variant COAD-US 16 2285362 2285362 deletion of <=200bp C - exon_variant COAD-US 16 2285362 2285362 deletion of <=200bp C - frameshift_variant T538 COAD-US 16 2285362 2285362 deletion of <=200bp C - frameshift_variant T715 COAD-US 16 2286845 2286845 single base substitution G A downstream_gene_variant COAD-US 16 2287517 2287517 single base substitution C T downstream_gene_variant COAD-US 16 2290114 2290114 single base substitution G A downstream_gene_variant COCA-CN 16 2282327 2282327 single base substitution C T 3_prime_UTR_variant COCA-CN 16 2282327 2282327 single base substitution C T exon_variant COCA-CN 16 2282327 2282327 single base substitution C T missense_variant R169C 505C>T COCA-CN 16 2282327 2282327 single base substitution C T missense_variant R191C 571C>T COCA-CN 16 2282327 2282327 single base substitution C T upstream_gene_variant COCA-CN 16 2282346 2282346 single base substitution G A 3_prime_UTR_variant COCA-CN 16 2282346 2282346 single base substitution G A exon_variant COCA-CN 16 2282346 2282346 single base substitution G A missense_variant C175Y 524G>A COCA-CN 16 2282346 2282346 single base substitution G A missense_variant C197Y 590G>A COCA-CN 16 2282346 2282346 single base substitution G A upstream_gene_variant COCA-CN 16 2282647 2282647 single base substitution C T intron_variant COCA-CN 16 2282647 2282647 single base substitution C T upstream_gene_variant COCA-CN 16 2283506 2283506 single base substitution T C downstream_gene_variant COCA-CN 16 2283506 2283506 single base substitution T C exon_variant COCA-CN 16 2283506 2283506 single base substitution T C missense_variant M375T 1124T>C COCA-CN 16 2283506 2283506 single base substitution T C splice_region_variant COCA-CN 16 2283506 2283506 single base substitution T C upstream_gene_variant COCA-CN 16 2283938 2283938 single base substitution G A downstream_gene_variant COCA-CN 16 2283938 2283938 single base substitution G A exon_variant COCA-CN 16 2283938 2283938 single base substitution G A intron_variant COCA-CN 16 2283938 2283938 single base substitution G A missense_variant S441N 1322G>A COCA-CN 16 2283938 2283938 single base substitution G A upstream_gene_variant COCA-CN 16 2284175 2284175 single base substitution C T downstream_gene_variant COCA-CN 16 2284175 2284175 single base substitution C T exon_variant COCA-CN 16 2284175 2284175 single base substitution C T intron_variant COCA-CN 16 2284175 2284175 single base substitution C T missense_variant P460L 1379C>T COCA-CN 16 2284175 2284175 single base substitution C T upstream_gene_variant COCA-CN 16 2285406 2285406 single base substitution G A 3_prime_UTR_variant COCA-CN 16 2285406 2285406 single base substitution G A downstream_gene_variant COCA-CN 16 2285406 2285406 single base substitution G A exon_variant COCA-CN 16 2285406 2285406 single base substitution G A missense_variant A553T 1657G>A COCA-CN 16 2285406 2285406 single base substitution G A missense_variant A730T 2188G>A COCA-CN 16 2286945 2286945 single base substitution G A downstream_gene_variant COCA-CN 16 2286979 2286979 single base substitution G C downstream_gene_variant COCA-CN 16 2287704 2287704 single base substitution T C downstream_gene_variant COCA-CN 16 2287738 2287738 single base substitution G A downstream_gene_variant COCA-CN 16 2287785 2287785 single base substitution C T downstream_gene_variant COCA-CN 16 2289941 2289941 single base substitution A G downstream_gene_variant COCA-CN 16 2290047 2290047 single base substitution A G downstream_gene_variant ESAD-UK 16 2269320 2269332 deletion of <=200bp TTTTTTATTTTTA - upstream_gene_variant ESAD-UK 16 2270681 2270681 single base substitution G A upstream_gene_variant ESAD-UK 16 2270781 2270781 single base substitution C T upstream_gene_variant ESAD-UK 16 2271167 2271167 single base substitution A T upstream_gene_variant ESAD-UK 16 2271405 2271405 insertion of <=200bp - T upstream_gene_variant ESAD-UK 16 2272883 2272883 single base substitution C T upstream_gene_variant ESAD-UK 16 2273506 2273506 single base substitution C G upstream_gene_variant ESAD-UK 16 2273550 2273550 single base substitution C A upstream_gene_variant ESAD-UK 16 2273840 2273853 deletion of <=200bp ATGGCCCGAGCTGC - frameshift_variant MARAA1 ESAD-UK 16 2273840 2273853 deletion of <=200bp ATGGCCCGAGCTGC - intron_variant ESAD-UK 16 2273840 2273853 deletion of <=200bp ATGGCCCGAGCTGC - upstream_gene_variant ESAD-UK 16 2273944 2273944 single base substitution C T intron_variant ESAD-UK 16 2273944 2273944 single base substitution C T upstream_gene_variant ESAD-UK 16 2275591 2275591 single base substitution C T intron_variant ESAD-UK 16 2275591 2275591 single base substitution C T upstream_gene_variant ESAD-UK 16 2278465 2278465 single base substitution C T exon_variant ESAD-UK 16 2278465 2278465 single base substitution C T missense_variant R62W 184C>T ESAD-UK 16 2278465 2278465 single base substitution C T missense_variant R84W 250C>T ESAD-UK 16 2278465 2278465 single base substitution C T upstream_gene_variant ESAD-UK 16 2279102 2279102 single base substitution C T intron_variant ESAD-UK 16 2279102 2279102 single base substitution C T upstream_gene_variant ESAD-UK 16 2283035 2283035 single base substitution T C downstream_gene_variant ESAD-UK 16 2283035 2283035 single base substitution T C exon_variant ESAD-UK 16 2283035 2283035 single base substitution T C synonymous_variant L303L 907T>C ESAD-UK 16 2283035 2283035 single base substitution T C upstream_gene_variant ESAD-UK 16 2285835 2285835 single base substitution C G downstream_gene_variant ESAD-UK 16 2285987 2285987 single base substitution G A downstream_gene_variant ESAD-UK 16 2288072 2288072 single base substitution C T downstream_gene_variant ESCA-CN 16 2282111 2282111 single base substitution A T exon_variant ESCA-CN 16 2282111 2282111 single base substitution A T intron_variant ESCA-CN 16 2282111 2282111 single base substitution A T upstream_gene_variant KIRP-US 16 2284711 2284711 single base substitution C T downstream_gene_variant KIRP-US 16 2284711 2284711 single base substitution C T exon_variant KIRP-US 16 2284711 2284711 single base substitution C T missense_variant P397L 1190C>T KIRP-US 16 2284711 2284711 single base substitution C T missense_variant P574L 1721C>T LAML-KR 16 2278509 2278509 single base substitution G A exon_variant LAML-KR 16 2278509 2278509 single base substitution G A synonymous_variant A76A 228G>A LAML-KR 16 2278509 2278509 single base substitution G A synonymous_variant A98A 294G>A LAML-KR 16 2278509 2278509 single base substitution G A upstream_gene_variant LGG-US 16 2279638 2279638 single base substitution C T exon_variant LGG-US 16 2279638 2279638 single base substitution C T missense_variant S104F 311C>T LGG-US 16 2279638 2279638 single base substitution C T missense_variant S126F 377C>T LGG-US 16 2279638 2279638 single base substitution C T upstream_gene_variant LGG-US 16 2282496 2282496 single base substitution C T 3_prime_UTR_variant LGG-US 16 2282496 2282496 single base substitution C T exon_variant LGG-US 16 2282496 2282496 single base substitution C T missense_variant R195C 583C>T LGG-US 16 2282496 2282496 single base substitution C T missense_variant R217C 649C>T LGG-US 16 2282496 2282496 single base substitution C T upstream_gene_variant LIAD-FR 16 2282324 2282324 single base substitution G A 3_prime_UTR_variant LIAD-FR 16 2282324 2282324 single base substitution G A exon_variant LIAD-FR 16 2282324 2282324 single base substitution G A missense_variant G168S 502G>A LIAD-FR 16 2282324 2282324 single base substitution G A missense_variant G190S 568G>A LIAD-FR 16 2282324 2282324 single base substitution G A upstream_gene_variant LICA-FR 16 2268710 2268710 deletion of <=200bp T - upstream_gene_variant LICA-FR 16 2273733 2273733 single base substitution G A 5_prime_UTR_variant LICA-FR 16 2273733 2273733 single base substitution G A exon_variant LICA-FR 16 2273733 2273733 single base substitution G A missense_variant S40N 119G>A LICA-FR 16 2273733 2273733 single base substitution G A upstream_gene_variant LICA-FR 16 2287956 2287956 single base substitution C A downstream_gene_variant LIHC-US 16 2282755 2282755 single base substitution A C splice_acceptor_variant LIHC-US 16 2282755 2282755 single base substitution A C upstream_gene_variant LINC-JP 16 2273743 2273743 single base substitution C T 5_prime_UTR_premature_start_codon_gain_variant LINC-JP 16 2273743 2273743 single base substitution C T exon_variant LINC-JP 16 2273743 2273743 single base substitution C T synonymous_variant L43L 129C>T LINC-JP 16 2273743 2273743 single base substitution C T upstream_gene_variant LINC-JP 16 2288126 2288126 single base substitution C T downstream_gene_variant LINC-JP 16 2288265 2288265 single base substitution G A downstream_gene_variant LIRI-JP 16 2270386 2270386 single base substitution A G upstream_gene_variant LIRI-JP 16 2274120 2274120 single base substitution C T intron_variant LIRI-JP 16 2274120 2274120 single base substitution C T upstream_gene_variant LIRI-JP 16 2274761 2274761 single base substitution G A intron_variant LIRI-JP 16 2274761 2274761 single base substitution G A upstream_gene_variant LIRI-JP 16 2285844 2285844 single base substitution C G downstream_gene_variant LIRI-JP 16 2290689 2290689 single base substitution T C downstream_gene_variant LUSC-KR 16 2285270 2285270 single base substitution C T 3_prime_UTR_variant LUSC-KR 16 2285270 2285270 single base substitution C T downstream_gene_variant LUSC-KR 16 2285270 2285270 single base substitution C T exon_variant LUSC-KR 16 2285270 2285270 single base substitution C T synonymous_variant A507A 1521C>T LUSC-KR 16 2285270 2285270 single base substitution C T synonymous_variant A684A 2052C>T LUSC-KR 16 2285357 2285357 single base substitution C T 3_prime_UTR_variant LUSC-KR 16 2285357 2285357 single base substitution C T downstream_gene_variant LUSC-KR 16 2285357 2285357 single base substitution C T exon_variant LUSC-KR 16 2285357 2285357 single base substitution C T synonymous_variant I536I 1608C>T LUSC-KR 16 2285357 2285357 single base substitution C T synonymous_variant I713I 2139C>T LUSC-KR 16 2289525 2289525 single base substitution G T downstream_gene_variant LUSC-US 16 2278471 2278471 single base substitution C T exon_variant LUSC-US 16 2278471 2278471 single base substitution C T missense_variant P64S 190C>T LUSC-US 16 2278471 2278471 single base substitution C T missense_variant P86S 256C>T LUSC-US 16 2278471 2278471 single base substitution C T upstream_gene_variant LUSC-US 16 2279622 2279622 single base substitution G C exon_variant LUSC-US 16 2279622 2279622 single base substitution G C missense_variant V121L 361G>C LUSC-US 16 2279622 2279622 single base substitution G C missense_variant V99L 295G>C LUSC-US 16 2279622 2279622 single base substitution G C upstream_gene_variant LUSC-US 16 2282275 2282275 single base substitution C G exon_variant LUSC-US 16 2282275 2282275 single base substitution C G synonymous_variant L151L 453C>G LUSC-US 16 2282275 2282275 single base substitution C G synonymous_variant L173L 519C>G LUSC-US 16 2282275 2282275 single base substitution C G upstream_gene_variant LUSC-US 16 2282359 2282359 single base substitution C G 3_prime_UTR_variant LUSC-US 16 2282359 2282359 single base substitution C G exon_variant LUSC-US 16 2282359 2282359 single base substitution C G missense_variant F179L 537C>G LUSC-US 16 2282359 2282359 single base substitution C G missense_variant F201L 603C>G LUSC-US 16 2282359 2282359 single base substitution C G upstream_gene_variant MALY-DE 16 2270496 2270496 single base substitution G A upstream_gene_variant MALY-DE 16 2290521 2290525 deletion of <=200bp TTTTG - downstream_gene_variant MELA-AU 16 2268815 2268815 single base substitution G A upstream_gene_variant MELA-AU 16 2268886 2268886 single base substitution C T upstream_gene_variant MELA-AU 16 2269148 2269148 single base substitution C T upstream_gene_variant MELA-AU 16 2270653 2270653 single base substitution C T upstream_gene_variant MELA-AU 16 2271064 2271064 single base substitution G C upstream_gene_variant MELA-AU 16 2271305 2271305 single base substitution C T upstream_gene_variant MELA-AU 16 2271307 2271307 single base substitution T A upstream_gene_variant MELA-AU 16 2271607 2271607 single base substitution T C upstream_gene_variant MELA-AU 16 2272056 2272056 single base substitution C G upstream_gene_variant MELA-AU 16 2273114 2273114 single base substitution C T upstream_gene_variant MELA-AU 16 2273659 2273659 single base substitution A G exon_variant MELA-AU 16 2273659 2273659 single base substitution A G synonymous_variant A15A 45A>G MELA-AU 16 2273659 2273659 single base substitution A G upstream_gene_variant MELA-AU 16 2274186 2274186 single base substitution C T intron_variant MELA-AU 16 2274186 2274186 single base substitution C T upstream_gene_variant MELA-AU 16 2274802 2274802 single base substitution C T intron_variant MELA-AU 16 2274802 2274802 single base substitution C T upstream_gene_variant MELA-AU 16 2275097 2275097 single base substitution C T intron_variant MELA-AU 16 2275097 2275097 single base substitution C T upstream_gene_variant MELA-AU 16 2275283 2275283 single base substitution G A intron_variant MELA-AU 16 2275283 2275283 single base substitution G A upstream_gene_variant MELA-AU 16 2276585 2276585 single base substitution G A intron_variant MELA-AU 16 2276585 2276585 single base substitution G A upstream_gene_variant MELA-AU 16 2276743 2276743 single base substitution C T intron_variant MELA-AU 16 2276743 2276743 single base substitution C T upstream_gene_variant MELA-AU 16 2277245 2277245 single base substitution C T intron_variant MELA-AU 16 2277245 2277245 single base substitution C T upstream_gene_variant MELA-AU 16 2277727 2277727 single base substitution C T intron_variant MELA-AU 16 2277727 2277727 single base substitution C T upstream_gene_variant MELA-AU 16 2278396 2278396 single base substitution G A exon_variant MELA-AU 16 2278396 2278396 single base substitution G A missense_variant G39S 115G>A MELA-AU 16 2278396 2278396 single base substitution G A missense_variant G61S 181G>A MELA-AU 16 2278396 2278396 single base substitution G A upstream_gene_variant MELA-AU 16 2278551 2278551 single base substitution C T intron_variant MELA-AU 16 2278551 2278551 single base substitution C T upstream_gene_variant MELA-AU 16 2278782 2278782 single base substitution C T intron_variant MELA-AU 16 2278782 2278782 single base substitution C T upstream_gene_variant MELA-AU 16 2279546 2279546 single base substitution C T intron_variant MELA-AU 16 2279546 2279546 single base substitution C T upstream_gene_variant MELA-AU 16 2279548 2279548 single base substitution C A intron_variant MELA-AU 16 2279548 2279548 single base substitution C A upstream_gene_variant MELA-AU 16 2279977 2279977 single base substitution C T exon_variant MELA-AU 16 2279977 2279977 single base substitution C T intron_variant MELA-AU 16 2279977 2279977 single base substitution C T upstream_gene_variant MELA-AU 16 2279985 2279985 single base substitution C T exon_variant MELA-AU 16 2279985 2279985 single base substitution C T intron_variant MELA-AU 16 2279985 2279985 single base substitution C T upstream_gene_variant MELA-AU 16 2280237 2280237 single base substitution C T exon_variant MELA-AU 16 2280237 2280237 single base substitution C T intron_variant MELA-AU 16 2280237 2280237 single base substitution C T upstream_gene_variant MELA-AU 16 2280744 2280744 single base substitution C T exon_variant MELA-AU 16 2280744 2280744 single base substitution C T intron_variant MELA-AU 16 2280744 2280744 single base substitution C T upstream_gene_variant MELA-AU 16 2280827 2280827 single base substitution C T exon_variant MELA-AU 16 2280827 2280827 single base substitution C T intron_variant MELA-AU 16 2280827 2280827 single base substitution C T upstream_gene_variant MELA-AU 16 2280878 2280878 single base substitution C T exon_variant MELA-AU 16 2280878 2280878 single base substitution C T intron_variant MELA-AU 16 2280878 2280878 single base substitution C T upstream_gene_variant MELA-AU 16 2280929 2280929 single base substitution C T exon_variant MELA-AU 16 2280929 2280929 single base substitution C T intron_variant MELA-AU 16 2280929 2280929 single base substitution C T upstream_gene_variant MELA-AU 16 2281076 2281076 single base substitution C T exon_variant MELA-AU 16 2281076 2281076 single base substitution C T intron_variant MELA-AU 16 2281076 2281076 single base substitution C T upstream_gene_variant MELA-AU 16 2281162 2281162 single base substitution C A exon_variant MELA-AU 16 2281162 2281162 single base substitution C A intron_variant MELA-AU 16 2281162 2281162 single base substitution C A upstream_gene_variant MELA-AU 16 2281340 2281340 single base substitution C T exon_variant MELA-AU 16 2281340 2281340 single base substitution C T intron_variant MELA-AU 16 2281340 2281340 single base substitution C T upstream_gene_variant MELA-AU 16 2282243 2282243 single base substitution C T exon_variant MELA-AU 16 2282243 2282243 single base substitution C T missense_variant P141S 421C>T MELA-AU 16 2282243 2282243 single base substitution C T missense_variant P163S 487C>T MELA-AU 16 2282243 2282243 single base substitution C T upstream_gene_variant MELA-AU 16 2282243 2282244 multiple base substitution (>=2bp and <=200bp) CC GT exon_variant MELA-AU 16 2282243 2282244 multiple base substitution (>=2bp and <=200bp) CC GT missense_variant P141V 421CC>GT MELA-AU 16 2282243 2282244 multiple base substitution (>=2bp and <=200bp) CC GT missense_variant P163V 487CC>GT MELA-AU 16 2282243 2282244 multiple base substitution (>=2bp and <=200bp) CC GT upstream_gene_variant MELA-AU 16 2282534 2282535 multiple base substitution (>=2bp and <=200bp) CC TT 3_prime_UTR_variant MELA-AU 16 2282534 2282535 multiple base substitution (>=2bp and <=200bp) CC TT exon_variant MELA-AU 16 2282534 2282535 multiple base substitution (>=2bp and <=200bp) CC TT missense_variant FR207FC MELA-AU 16 2282534 2282535 multiple base substitution (>=2bp and <=200bp) CC TT missense_variant FR229FC MELA-AU 16 2282534 2282535 multiple base substitution (>=2bp and <=200bp) CC TT upstream_gene_variant MELA-AU 16 2282681 2282681 single base substitution C T intron_variant MELA-AU 16 2282681 2282681 single base substitution C T upstream_gene_variant MELA-AU 16 2283076 2283076 single base substitution G A downstream_gene_variant MELA-AU 16 2283076 2283076 single base substitution G A exon_variant MELA-AU 16 2283076 2283076 single base substitution G A synonymous_variant E316E 948G>A MELA-AU 16 2283076 2283076 single base substitution G A upstream_gene_variant MELA-AU 16 2283078 2283078 single base substitution C T downstream_gene_variant MELA-AU 16 2283078 2283078 single base substitution C T exon_variant MELA-AU 16 2283078 2283078 single base substitution C T missense_variant T317I 950C>T MELA-AU 16 2283078 2283078 single base substitution C T upstream_gene_variant MELA-AU 16 2283501 2283501 single base substitution G A downstream_gene_variant MELA-AU 16 2283501 2283501 single base substitution G A exon_variant MELA-AU 16 2283501 2283501 single base substitution G A splice_region_variant MELA-AU 16 2283501 2283501 single base substitution G A synonymous_variant Q373Q 1119G>A MELA-AU 16 2283501 2283501 single base substitution G A upstream_gene_variant MELA-AU 16 2283619 2283620 multiple base substitution (>=2bp and <=200bp) CC AT downstream_gene_variant MELA-AU 16 2283619 2283620 multiple base substitution (>=2bp and <=200bp) CC AT exon_variant MELA-AU 16 2283619 2283620 multiple base substitution (>=2bp and <=200bp) CC AT intron_variant MELA-AU 16 2283619 2283620 multiple base substitution (>=2bp and <=200bp) CC AT missense_variant P413M 1237CC>AT MELA-AU 16 2283619 2283620 multiple base substitution (>=2bp and <=200bp) CC AT upstream_gene_variant MELA-AU 16 2284183 2284183 single base substitution T A downstream_gene_variant MELA-AU 16 2284183 2284183 single base substitution T A exon_variant MELA-AU 16 2284183 2284183 single base substitution T A intron_variant MELA-AU 16 2284183 2284183 single base substitution T A missense_variant F463I 1387T>A MELA-AU 16 2284183 2284183 single base substitution T A upstream_gene_variant MELA-AU 16 2284438 2284438 single base substitution C T downstream_gene_variant MELA-AU 16 2284438 2284438 single base substitution C T exon_variant MELA-AU 16 2284438 2284438 single base substitution C T intron_variant MELA-AU 16 2284438 2284438 single base substitution C T upstream_gene_variant MELA-AU 16 2284658 2284658 single base substitution C T downstream_gene_variant MELA-AU 16 2284658 2284658 single base substitution C T exon_variant MELA-AU 16 2284658 2284658 single base substitution C T synonymous_variant F379F 1137C>T MELA-AU 16 2284658 2284658 single base substitution C T synonymous_variant F556F 1668C>T MELA-AU 16 2285001 2285001 single base substitution A G downstream_gene_variant MELA-AU 16 2285001 2285001 single base substitution A G exon_variant MELA-AU 16 2285001 2285001 single base substitution A G intron_variant MELA-AU 16 2285001 2285001 single base substitution A G missense_variant E468G 1403A>G MELA-AU 16 2285001 2285001 single base substitution A G missense_variant E645G 1934A>G MELA-AU 16 2285285 2285285 single base substitution C T 3_prime_UTR_variant MELA-AU 16 2285285 2285285 single base substitution C T downstream_gene_variant MELA-AU 16 2285285 2285285 single base substitution C T exon_variant MELA-AU 16 2285285 2285285 single base substitution C T synonymous_variant I512I 1536C>T MELA-AU 16 2285285 2285285 single base substitution C T synonymous_variant I689I 2067C>T MELA-AU 16 2285683 2285683 single base substitution C T 3_prime_UTR_variant MELA-AU 16 2285683 2285683 single base substitution C T downstream_gene_variant MELA-AU 16 2285683 2285683 single base substitution C T exon_variant MELA-AU 16 2286263 2286263 single base substitution G A downstream_gene_variant MELA-AU 16 2286491 2286492 multiple base substitution (>=2bp and <=200bp) CC TT downstream_gene_variant MELA-AU 16 2286698 2286698 single base substitution G A downstream_gene_variant MELA-AU 16 2286841 2286841 single base substitution G A downstream_gene_variant MELA-AU 16 2287322 2287322 single base substitution G A downstream_gene_variant MELA-AU 16 2288725 2288725 single base substitution G A downstream_gene_variant MELA-AU 16 2289296 2289296 single base substitution C T downstream_gene_variant MELA-AU 16 2289767 2289767 single base substitution C T downstream_gene_variant MELA-AU 16 2290030 2290030 single base substitution G A downstream_gene_variant MELA-AU 16 2290546 2290546 single base substitution G A downstream_gene_variant ORCA-IN 16 2278466 2278466 single base substitution G A exon_variant ORCA-IN 16 2278466 2278466 single base substitution G A missense_variant R62Q 185G>A ORCA-IN 16 2278466 2278466 single base substitution G A missense_variant R84Q 251G>A ORCA-IN 16 2278466 2278466 single base substitution G A upstream_gene_variant ORCA-IN 16 2282234 2282234 single base substitution G T exon_variant ORCA-IN 16 2282234 2282234 single base substitution G T missense_variant A138S 412G>T ORCA-IN 16 2282234 2282234 single base substitution G T missense_variant A160S 478G>T ORCA-IN 16 2282234 2282234 single base substitution G T upstream_gene_variant ORCA-IN 16 2283166 2283166 single base substitution G C downstream_gene_variant ORCA-IN 16 2283166 2283166 single base substitution G C exon_variant ORCA-IN 16 2283166 2283166 single base substitution G C missense_variant M346I 1038G>C ORCA-IN 16 2283166 2283166 single base substitution G C upstream_gene_variant ORCA-IN 16 2285411 2285411 single base substitution C T 3_prime_UTR_variant ORCA-IN 16 2285411 2285411 single base substitution C T downstream_gene_variant ORCA-IN 16 2285411 2285411 single base substitution C T exon_variant ORCA-IN 16 2285411 2285411 single base substitution C T synonymous_variant I554I 1662C>T ORCA-IN 16 2285411 2285411 single base substitution C T synonymous_variant I731I 2193C>T ORCA-IN 16 2285542 2285542 single base substitution G T 3_prime_UTR_variant ORCA-IN 16 2285542 2285542 single base substitution G T downstream_gene_variant ORCA-IN 16 2285542 2285542 single base substitution G T exon_variant ORCA-IN 16 2285542 2285542 single base substitution G T missense_variant G598V 1793G>T ORCA-IN 16 2285542 2285542 single base substitution G T missense_variant G775V 2324G>T ORCA-IN 16 2287592 2287592 single base substitution C A downstream_gene_variant ORCA-IN 16 2287600 2287600 single base substitution G T downstream_gene_variant OV-AU 16 2269983 2269983 single base substitution C T upstream_gene_variant OV-AU 16 2272946 2272946 single base substitution C G upstream_gene_variant OV-AU 16 2276015 2276015 single base substitution G A intron_variant OV-AU 16 2276015 2276015 single base substitution G A upstream_gene_variant OV-AU 16 2276832 2276832 single base substitution G A intron_variant OV-AU 16 2276832 2276832 single base substitution G A upstream_gene_variant OV-AU 16 2278399 2278399 single base substitution C T exon_variant OV-AU 16 2278399 2278399 single base substitution C T missense_variant R40C 118C>T OV-AU 16 2278399 2278399 single base substitution C T missense_variant R62C 184C>T OV-AU 16 2278399 2278399 single base substitution C T upstream_gene_variant OV-AU 16 2281968 2281968 single base substitution G A exon_variant OV-AU 16 2281968 2281968 single base substitution G A intron_variant OV-AU 16 2281968 2281968 single base substitution G A upstream_gene_variant OV-AU 16 2287635 2287635 single base substitution C G downstream_gene_variant OV-US 16 2282783 2282783 single base substitution T G downstream_gene_variant OV-US 16 2282783 2282783 single base substitution T G exon_variant OV-US 16 2282783 2282783 single base substitution T G missense_variant C231G 691T>G OV-US 16 2282783 2282783 single base substitution T G missense_variant C253G 757T>G OV-US 16 2282783 2282783 single base substitution T G upstream_gene_variant PACA-AU 16 2270110 2270110 single base substitution A G upstream_gene_variant PACA-AU 16 2272152 2272152 single base substitution G T upstream_gene_variant PACA-AU 16 2273966 2273966 single base substitution C A intron_variant PACA-AU 16 2273966 2273966 single base substitution C A upstream_gene_variant PACA-AU 16 2275834 2275834 single base substitution C T intron_variant PACA-AU 16 2275834 2275834 single base substitution C T upstream_gene_variant PACA-AU 16 2286545 2286545 single base substitution C T downstream_gene_variant PACA-AU 16 2289354 2289354 insertion of <=200bp - TGGTAACT downstream_gene_variant PACA-CA 16 2269915 2269915 single base substitution G A upstream_gene_variant PACA-CA 16 2269938 2269938 single base substitution C T upstream_gene_variant PACA-CA 16 2271010 2271010 deletion of <=200bp A - upstream_gene_variant PACA-CA 16 2271817 2271817 single base substitution G T upstream_gene_variant PACA-CA 16 2275481 2275481 single base substitution T C intron_variant PACA-CA 16 2275481 2275481 single base substitution T C upstream_gene_variant PACA-CA 16 2276369 2276369 single base substitution C T intron_variant PACA-CA 16 2276369 2276369 single base substitution C T upstream_gene_variant PACA-CA 16 2277313 2277313 single base substitution T C intron_variant PACA-CA 16 2277313 2277313 single base substitution T C upstream_gene_variant PACA-CA 16 2281818 2281818 single base substitution G A exon_variant PACA-CA 16 2281818 2281818 single base substitution G A intron_variant PACA-CA 16 2281818 2281818 single base substitution G A upstream_gene_variant PACA-CA 16 2282260 2282260 single base substitution G A exon_variant PACA-CA 16 2282260 2282260 single base substitution G A synonymous_variant Q146Q 438G>A PACA-CA 16 2282260 2282260 single base substitution G A synonymous_variant Q168Q 504G>A PACA-CA 16 2282260 2282260 single base substitution G A upstream_gene_variant PACA-CA 16 2282375 2282375 single base substitution C T intron_variant PACA-CA 16 2282375 2282375 single base substitution C T upstream_gene_variant PACA-CA 16 2282376 2282376 single base substitution G A intron_variant PACA-CA 16 2282376 2282376 single base substitution G A upstream_gene_variant PACA-CA 16 2282426 2282426 single base substitution G C intron_variant PACA-CA 16 2282426 2282426 single base substitution G C upstream_gene_variant PACA-CA 16 2282904 2282904 single base substitution G A downstream_gene_variant PACA-CA 16 2282904 2282904 single base substitution G A exon_variant PACA-CA 16 2282904 2282904 single base substitution G A missense_variant R271H 812G>A PACA-CA 16 2282904 2282904 single base substitution G A missense_variant R293H 878G>A PACA-CA 16 2282904 2282904 single base substitution G A upstream_gene_variant PACA-CA 16 2285068 2285068 single base substitution G T downstream_gene_variant PACA-CA 16 2285068 2285068 single base substitution G T exon_variant PACA-CA 16 2285068 2285068 single base substitution G T intron_variant PACA-CA 16 2285095 2285095 single base substitution A G downstream_gene_variant PACA-CA 16 2285095 2285095 single base substitution A G exon_variant PACA-CA 16 2285095 2285095 single base substitution A G missense_variant D473G 1418A>G PACA-CA 16 2285095 2285095 single base substitution A G missense_variant D650G 1949A>G PACA-CA 16 2285095 2285095 single base substitution A G missense_variant M633V 1897A>G PACA-CA 16 2290525 2290525 single base substitution G T downstream_gene_variant PAEN-AU 16 2269983 2269983 single base substitution C T upstream_gene_variant PBCA-DE 16 2273637 2273637 single base substitution G C exon_variant PBCA-DE 16 2273637 2273637 single base substitution G C missense_variant R8P 23G>C PBCA-DE 16 2273637 2273637 single base substitution G C upstream_gene_variant PRAD-CA 16 2283691 2283691 single base substitution C T downstream_gene_variant PRAD-CA 16 2283691 2283691 single base substitution C T exon_variant PRAD-CA 16 2283691 2283691 single base substitution C T intron_variant PRAD-CA 16 2283691 2283691 single base substitution C T upstream_gene_variant PRAD-CA 16 2288605 2288605 single base substitution C T downstream_gene_variant PRAD-UK 16 2272106 2272106 single base substitution C T upstream_gene_variant PRAD-UK 16 2275461 2275461 single base substitution C T intron_variant PRAD-UK 16 2275461 2275461 single base substitution C T upstream_gene_variant PRAD-US 16 2290114 2290114 single base substitution G A downstream_gene_variant READ-US 16 2282234 2282234 single base substitution G A exon_variant READ-US 16 2282234 2282234 single base substitution G A missense_variant A138T 412G>A READ-US 16 2282234 2282234 single base substitution G A missense_variant A160T 478G>A READ-US 16 2282234 2282234 single base substitution G A upstream_gene_variant READ-US 16 2283951 2283951 single base substitution G A downstream_gene_variant READ-US 16 2283951 2283951 single base substitution G A exon_variant READ-US 16 2283951 2283951 single base substitution G A intron_variant READ-US 16 2283951 2283951 single base substitution G A synonymous_variant P445P 1335G>A READ-US 16 2283951 2283951 single base substitution G A upstream_gene_variant READ-US 16 2287249 2287249 single base substitution C T downstream_gene_variant READ-US 16 2287545 2287545 single base substitution G T downstream_gene_variant RECA-EU 16 2272940 2272940 single base substitution G A upstream_gene_variant RECA-EU 16 2276951 2276951 single base substitution C G intron_variant RECA-EU 16 2276951 2276951 single base substitution C G upstream_gene_variant RECA-EU 16 2286456 2286456 single base substitution C A downstream_gene_variant RECA-EU 16 2288558 2288558 single base substitution C T downstream_gene_variant SKCA-BR 16 2268700 2268700 single base substitution A C upstream_gene_variant SKCA-BR 16 2270257 2270257 single base substitution C T upstream_gene_variant SKCA-BR 16 2272818 2272818 single base substitution T C upstream_gene_variant SKCA-BR 16 2275804 2275804 single base substitution A T intron_variant SKCA-BR 16 2275804 2275804 single base substitution A T upstream_gene_variant SKCA-BR 16 2275808 2275808 single base substitution A T intron_variant SKCA-BR 16 2275808 2275808 single base substitution A T upstream_gene_variant SKCA-BR 16 2275832 2275832 single base substitution C T intron_variant SKCA-BR 16 2275832 2275832 single base substitution C T upstream_gene_variant SKCA-BR 16 2278749 2278749 single base substitution C T intron_variant SKCA-BR 16 2278749 2278749 single base substitution C T upstream_gene_variant SKCA-BR 16 2279080 2279080 single base substitution C T intron_variant SKCA-BR 16 2279080 2279080 single base substitution C T upstream_gene_variant SKCA-BR 16 2280880 2280880 single base substitution C T exon_variant SKCA-BR 16 2280880 2280880 single base substitution C T intron_variant SKCA-BR 16 2280880 2280880 single base substitution C T upstream_gene_variant SKCA-BR 16 2280898 2280898 single base substitution T G exon_variant SKCA-BR 16 2280898 2280898 single base substitution T G intron_variant SKCA-BR 16 2280898 2280898 single base substitution T G upstream_gene_variant SKCA-BR 16 2284528 2284528 single base substitution A G downstream_gene_variant SKCA-BR 16 2284528 2284528 single base substitution A G exon_variant SKCA-BR 16 2284528 2284528 single base substitution A G intron_variant SKCA-BR 16 2284528 2284528 single base substitution A G upstream_gene_variant SKCA-BR 16 2284658 2284658 single base substitution C T downstream_gene_variant SKCA-BR 16 2284658 2284658 single base substitution C T exon_variant SKCA-BR 16 2284658 2284658 single base substitution C T synonymous_variant F379F 1137C>T SKCA-BR 16 2284658 2284658 single base substitution C T synonymous_variant F556F 1668C>T SKCA-BR 16 2285168 2285168 single base substitution C G downstream_gene_variant SKCA-BR 16 2285168 2285168 single base substitution C G exon_variant SKCA-BR 16 2285168 2285168 single base substitution C G intron_variant SKCA-BR 16 2287496 2287496 single base substitution T C downstream_gene_variant SKCA-BR 16 2287501 2287501 single base substitution T C downstream_gene_variant SKCM-US 16 2282530 2282530 single base substitution C T 3_prime_UTR_variant SKCM-US 16 2282530 2282530 single base substitution C T exon_variant SKCM-US 16 2282530 2282530 single base substitution C T missense_variant S206F 617C>T SKCM-US 16 2282530 2282530 single base substitution C T missense_variant S228F 683C>T SKCM-US 16 2282530 2282530 single base substitution C T upstream_gene_variant SKCM-US 16 2283125 2283125 single base substitution C T downstream_gene_variant SKCM-US 16 2283125 2283125 single base substitution C T exon_variant SKCM-US 16 2283125 2283125 single base substitution C T missense_variant H333Y 997C>T SKCM-US 16 2283125 2283125 single base substitution C T upstream_gene_variant SKCM-US 16 2283156 2283156 single base substitution C T downstream_gene_variant SKCM-US 16 2283156 2283156 single base substitution C T exon_variant SKCM-US 16 2283156 2283156 single base substitution C T missense_variant S343F 1028C>T SKCM-US 16 2283156 2283156 single base substitution C T upstream_gene_variant SKCM-US 16 2283184 2283184 single base substitution G A downstream_gene_variant SKCM-US 16 2283184 2283184 single base substitution G A exon_variant SKCM-US 16 2283184 2283184 single base substitution G A splice_region_variant SKCM-US 16 2283184 2283184 single base substitution G A upstream_gene_variant SKCM-US 16 2284180 2284180 single base substitution C T downstream_gene_variant SKCM-US 16 2284180 2284180 single base substitution C T exon_variant SKCM-US 16 2284180 2284180 single base substitution C T intron_variant SKCM-US 16 2284180 2284180 single base substitution C T missense_variant P462S 1384C>T SKCM-US 16 2284180 2284180 single base substitution C T upstream_gene_variant SKCM-US 16 2284185 2284185 single base substitution C T downstream_gene_variant SKCM-US 16 2284185 2284185 single base substitution C T exon_variant SKCM-US 16 2284185 2284185 single base substitution C T intron_variant SKCM-US 16 2284185 2284185 single base substitution C T synonymous_variant F463F 1389C>T SKCM-US 16 2284185 2284185 single base substitution C T upstream_gene_variant SKCM-US 16 2284186 2284186 single base substitution G C downstream_gene_variant SKCM-US 16 2284186 2284186 single base substitution G C exon_variant SKCM-US 16 2284186 2284186 single base substitution G C intron_variant SKCM-US 16 2284186 2284186 single base substitution G C missense_variant A464P 1390G>C SKCM-US 16 2284186 2284186 single base substitution G C upstream_gene_variant SKCM-US 16 2284258 2284258 single base substitution G A downstream_gene_variant SKCM-US 16 2284258 2284258 single base substitution G A exon_variant SKCM-US 16 2284258 2284258 single base substitution G A intron_variant SKCM-US 16 2284258 2284258 single base substitution G A missense_variant E488K 1462G>A SKCM-US 16 2284258 2284258 single base substitution G A upstream_gene_variant SKCM-US 16 2285285 2285285 single base substitution C T 3_prime_UTR_variant SKCM-US 16 2285285 2285285 single base substitution C T downstream_gene_variant SKCM-US 16 2285285 2285285 single base substitution C T exon_variant SKCM-US 16 2285285 2285285 single base substitution C T synonymous_variant I512I 1536C>T SKCM-US 16 2285285 2285285 single base substitution C T synonymous_variant I689I 2067C>T SKCM-US 16 2285568 2285568 single base substitution G A 3_prime_UTR_variant SKCM-US 16 2285568 2285568 single base substitution G A downstream_gene_variant SKCM-US 16 2285568 2285568 single base substitution G A exon_variant SKCM-US 16 2285568 2285568 single base substitution G A missense_variant V607I 1819G>A SKCM-US 16 2285568 2285568 single base substitution G A missense_variant V784I 2350G>A SKCM-US 16 2287545 2287545 single base substitution G A downstream_gene_variant SKCM-US 16 2290030 2290030 single base substitution G A downstream_gene_variant STAD-US 16 2273712 2273712 single base substitution T C exon_variant STAD-US 16 2273712 2273712 single base substitution T C missense_variant V33A 98T>C STAD-US 16 2273712 2273712 single base substitution T C upstream_gene_variant STAD-US 16 2278379 2278379 single base substitution A G exon_variant STAD-US 16 2278379 2278379 single base substitution A G missense_variant D33G 98A>G STAD-US 16 2278379 2278379 single base substitution A G missense_variant D55G 164A>G STAD-US 16 2278379 2278379 single base substitution A G upstream_gene_variant STAD-US 16 2278400 2278400 single base substitution G A exon_variant STAD-US 16 2278400 2278400 single base substitution G A missense_variant R40H 119G>A STAD-US 16 2278400 2278400 single base substitution G A missense_variant R62H 185G>A STAD-US 16 2278400 2278400 single base substitution G A upstream_gene_variant STAD-US 16 2279661 2279661 single base substitution G A exon_variant STAD-US 16 2279661 2279661 single base substitution G A missense_variant A112T 334G>A STAD-US 16 2279661 2279661 single base substitution G A missense_variant A134T 400G>A STAD-US 16 2279661 2279661 single base substitution G A upstream_gene_variant STAD-US 16 2282763 2282763 single base substitution G A 3_prime_UTR_variant STAD-US 16 2282763 2282763 single base substitution G A exon_variant STAD-US 16 2282763 2282763 single base substitution G A missense_variant R224H 671G>A STAD-US 16 2282763 2282763 single base substitution G A missense_variant R246H 737G>A STAD-US 16 2282763 2282763 single base substitution G A upstream_gene_variant STAD-US 16 2282806 2282806 single base substitution G A downstream_gene_variant STAD-US 16 2282806 2282806 single base substitution G A exon_variant STAD-US 16 2282806 2282806 single base substitution G A synonymous_variant S238S 714G>A STAD-US 16 2282806 2282806 single base substitution G A synonymous_variant S260S 780G>A STAD-US 16 2282806 2282806 single base substitution G A upstream_gene_variant STAD-US 16 2284179 2284179 single base substitution G A downstream_gene_variant STAD-US 16 2284179 2284179 single base substitution G A exon_variant STAD-US 16 2284179 2284179 single base substitution G A intron_variant STAD-US 16 2284179 2284179 single base substitution G A synonymous_variant R461R 1383G>A STAD-US 16 2284179 2284179 single base substitution G A upstream_gene_variant STAD-US 16 2284270 2284270 single base substitution C T downstream_gene_variant STAD-US 16 2284270 2284270 single base substitution C T exon_variant STAD-US 16 2284270 2284270 single base substitution C T intron_variant STAD-US 16 2284270 2284270 single base substitution C T missense_variant R492C 1474C>T STAD-US 16 2284270 2284270 single base substitution C T upstream_gene_variant STAD-US 16 2285285 2285285 single base substitution C T 3_prime_UTR_variant STAD-US 16 2285285 2285285 single base substitution C T downstream_gene_variant STAD-US 16 2285285 2285285 single base substitution C T exon_variant STAD-US 16 2285285 2285285 single base substitution C T synonymous_variant I512I 1536C>T STAD-US 16 2285285 2285285 single base substitution C T synonymous_variant I689I 2067C>T STAD-US 16 2285333 2285333 single base substitution G A 3_prime_UTR_variant STAD-US 16 2285333 2285333 single base substitution G A downstream_gene_variant STAD-US 16 2285333 2285333 single base substitution G A exon_variant STAD-US 16 2285333 2285333 single base substitution G A synonymous_variant A528A 1584G>A STAD-US 16 2285333 2285333 single base substitution G A synonymous_variant A705A 2115G>A STAD-US 16 2285362 2285362 deletion of <=200bp C - 3_prime_UTR_variant STAD-US 16 2285362 2285362 deletion of <=200bp C - downstream_gene_variant STAD-US 16 2285362 2285362 deletion of <=200bp C - exon_variant STAD-US 16 2285362 2285362 deletion of <=200bp C - frameshift_variant T538 STAD-US 16 2285362 2285362 deletion of <=200bp C - frameshift_variant T715 STAD-US 16 2285460 2285460 single base substitution C T 3_prime_UTR_variant STAD-US 16 2285460 2285460 single base substitution C T downstream_gene_variant STAD-US 16 2285460 2285460 single base substitution C T exon_variant STAD-US 16 2285460 2285460 single base substitution C T stop_gained Q571* 1711C>T STAD-US 16 2285460 2285460 single base substitution C T stop_gained Q748* 2242C>T STAD-US 16 2287831 2287831 single base substitution G A downstream_gene_variant STAD-US 16 2287970 2287970 single base substitution C T downstream_gene_variant STAD-US 16 2290000 2290000 single base substitution G A downstream_gene_variant STAD-US 16 2290019 2290019 single base substitution C A downstream_gene_variant STAD-US 16 2290126 2290126 single base substitution T C downstream_gene_variant THCA-SA 16 2287496 2287496 single base substitution T C downstream_gene_variant UCEC-US 16 2278450 2278450 single base substitution C A exon_variant UCEC-US 16 2278450 2278450 single base substitution C A missense_variant Q57K 169C>A UCEC-US 16 2278450 2278450 single base substitution C A missense_variant Q79K 235C>A UCEC-US 16 2278450 2278450 single base substitution C A upstream_gene_variant UCEC-US 16 2282320 2282320 single base substitution G T 3_prime_UTR_variant UCEC-US 16 2282320 2282320 single base substitution G T exon_variant UCEC-US 16 2282320 2282320 single base substitution G T missense_variant K166N 498G>T UCEC-US 16 2282320 2282320 single base substitution G T missense_variant K188N 564G>T UCEC-US 16 2282320 2282320 single base substitution G T upstream_gene_variant UCEC-US 16 2282838 2282838 single base substitution C T downstream_gene_variant UCEC-US 16 2282838 2282838 single base substitution C T exon_variant UCEC-US 16 2282838 2282838 single base substitution C T missense_variant T249I 746C>T UCEC-US 16 2282838 2282838 single base substitution C T missense_variant T271I 812C>T UCEC-US 16 2282838 2282838 single base substitution C T upstream_gene_variant UCEC-US 16 2282891 2282892 deletion of <=200bp AA - downstream_gene_variant UCEC-US 16 2282891 2282892 deletion of <=200bp AA - exon_variant UCEC-US 16 2282891 2282892 deletion of <=200bp AA - frameshift_variant K267 UCEC-US 16 2282891 2282892 deletion of <=200bp AA - frameshift_variant K289 UCEC-US 16 2282891 2282892 deletion of <=200bp AA - upstream_gene_variant UCEC-US 16 2283011 2283011 single base substitution G T downstream_gene_variant UCEC-US 16 2283011 2283011 single base substitution G T exon_variant UCEC-US 16 2283011 2283011 single base substitution G T splice_acceptor_variant UCEC-US 16 2283011 2283011 single base substitution G T upstream_gene_variant UCEC-US 16 2283030 2283030 single base substitution C T downstream_gene_variant UCEC-US 16 2283030 2283030 single base substitution C T exon_variant UCEC-US 16 2283030 2283030 single base substitution C T missense_variant A301V 902C>T UCEC-US 16 2283030 2283030 single base substitution C T upstream_gene_variant UCEC-US 16 2284212 2284212 single base substitution C T downstream_gene_variant UCEC-US 16 2284212 2284212 single base substitution C T exon_variant UCEC-US 16 2284212 2284212 single base substitution C T intron_variant UCEC-US 16 2284212 2284212 single base substitution C T synonymous_variant F472F 1416C>T UCEC-US 16 2284212 2284212 single base substitution C T upstream_gene_variant UCEC-US 16 2284690 2284690 single base substitution G A downstream_gene_variant UCEC-US 16 2284690 2284690 single base substitution G A exon_variant UCEC-US 16 2284690 2284690 single base substitution G A missense_variant R390Q 1169G>A UCEC-US 16 2284690 2284690 single base substitution G A missense_variant R567Q 1700G>A UCEC-US 16 2285069 2285069 single base substitution C T downstream_gene_variant UCEC-US 16 2285069 2285069 single base substitution C T exon_variant UCEC-US 16 2285069 2285069 single base substitution C T intron_variant UCEC-US 16 2285132 2285132 single base substitution C T downstream_gene_variant UCEC-US 16 2285132 2285132 single base substitution C T exon_variant UCEC-US 16 2285132 2285132 single base substitution C T missense_variant A645V 1934C>T UCEC-US 16 2285132 2285132 single base substitution C T synonymous_variant G485G 1455C>T UCEC-US 16 2285132 2285132 single base substitution C T synonymous_variant G662G 1986C>T UCEC-US 16 2285339 2285339 single base substitution C T 3_prime_UTR_variant UCEC-US 16 2285339 2285339 single base substitution C T downstream_gene_variant UCEC-US 16 2285339 2285339 single base substitution C T exon_variant UCEC-US 16 2285339 2285339 single base substitution C T synonymous_variant A530A 1590C>T UCEC-US 16 2285339 2285339 single base substitution C T synonymous_variant A707A 2121C>T UCEC-US 16 2287041 2287041 single base substitution C T downstream_gene_variant UCEC-US 16 2287847 2287847 single base substitution G A downstream_gene_variant UCEC-US 16 2290058 2290058 single base substitution G A downstream_gene_variant

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand CSCC-16-T COSM4468706 c.1559C>T p.P520L Substitution - Missense 16:2234354-2234354 + I2L-P7-Tumor-Organoid COSM5363712 c.311T>C p.V104A Substitution - Missense 16:2229571-2229571 + PCSI_0083_Pa_P_526 COSM3787117 c.1949A>G p.D650G Substitution - Missense 16:2235094-2235094 + 49M COSM1376708 c.1474C>T p.R492C Substitution - Missense 16:2234269-2234269 + TCGA-D9-A4Z6-01 COSM3507698 c.831C>T p.I277I Substitution - coding silent 16:2232856-2232856 + ORL-48 COSM4596468 c.230A>C p.K77T Substitution - Missense 16:2228444-2228444 + S02354 COSM5695558 c.1065C>G p.V355V Substitution - coding silent 16:2233446-2233446 + PCSI_0083_Pa_X COSM3377830 c.878G>A p.R293H Substitution - Missense 16:2232903-2232903 + TCGA-AG-4021-01 COSM3420858 c.1335G>A p.P445P Substitution - coding silent 16:2233950-2233950 + TCGA-BR-8380-01 COSM4059322 c.2115G>A p.A705A Substitution - coding silent 16:2235332-2235332 + TCGA-AD-6889-01 COSM1376707 c.1339G>A p.A447T Substitution - Missense 16:2233954-2233954 + TCGA-66-2771-01 COSM703014 c.519C>G p.L173L Substitution - coding silent 16:2232274-2232274 + SNU-175 COSM4650367 c.1265C>T p.T422I Substitution - Missense 16:2233646-2233646 + CSCC-27-T COSM4466431 c.1434C>T p.L478L Substitution - coding silent 16:2234229-2234229 + TCGA-D3-A51J-06 COSM3507699 c.997C>T p.H333Y Substitution - Missense 16:2233124-2233124 + AOCS-093-1-9 COSM3948381 c.184C>T p.R62C Substitution - Missense 16:2228398-2228398 + B104-0-Tumor COSM1756915 c.1497C>G p.L499L Substitution - coding silent 16:2234292-2234292 + TCGA-BS-A0UV-01 COSM968655 c.235C>A p.Q79K Substitution - Missense 16:2228449-2228449 + TCGA-AZ-4323-01 COSM1376702 c.728C>T p.T243M Substitution - Missense 16:2232574-2232574 + NB-0445 COSM1284678 c.1057-1_1057insC p.V355fs*14 Unknown 16:2233437-2233438 + TCGA-CG-5721-01 COSM4059316 c.164A>G p.D55G Substitution - Missense 16:2228378-2228378 + OSCC-GB_01360111 COSM5955541 c.251G>A p.R84Q Substitution - Missense 16:2228465-2228465 + CSCC-11-T COSM968663 c.1416C>T p.F472F Substitution - coding silent 16:2234211-2234211 + I2L-P19Ta-Tumor-Biopsy COSM5363330 c.1423G>A p.A475T Substitution - Missense 16:2234218-2234218 + CRC-31T COSM5457833 c.1379C>T p.P460L Substitution - Missense 16:2234174-2234174 + PD17994a COSM5790498 c.1875G>A p.P625P Substitution - coding silent 16:2234941-2234941 + PTC-7C COSM4128818 c.500G>A p.R167H Substitution - Missense 16:2232255-2232255 + SNUH_G79_S1 COSM3679229 c.1684C>A p.L562M Substitution - Missense 16:2234673-2234673 + CRC-19T COSM5481287 c.1322G>A p.S441N Substitution - Missense 16:2233937-2233937 + S0004 COSM5882683 c.2320G>A p.E774K Substitution - Missense 16:2235537-2235537 + TCGA-AZ-4615-01 COSM3754797 c.2139C>T p.I713I Substitution - coding silent 16:2235356-2235356 + TCGA-FS-A1ZK-06 COSM3507703 c.1390G>C p.A464P Substitution - Missense 16:2234185-2234185 + CHC892T COSM4958968 c.119G>A p.S40N Substitution - Missense 16:2223732-2223732 + PCSI_0083_Pa_P_526 COSM3787116 c.504G>A p.Q168Q Substitution - coding silent 16:2232259-2232259 + B62-0-Tumor COSM1749486 c.1952C>T p.A651V Substitution - Missense 16:2235097-2235097 + TCGA-EI-6882-01 COSM3420857 c.478G>A p.A160T Substitution - Missense 16:2232233-2232233 + YUROS COSM5384517 c.15G>A p.M5I Substitution - Missense 16:2223628-2223628 + YUROG COSM228635 c.1841C>T p.P614L Substitution - Missense 16:2234907-2234907 + TCGA-D3-A2JP-06 COSM3507701 c.1056G>A p.E352E Substitution - coding silent 16:2233183-2233183 + 46M COSM5587695 c.1609C>A p.H537N Substitution - Missense 16:2234598-2234598 + 92 COSM5015346 c.838A>G p.S280G Substitution - Missense 16:2232863-2232863 + OSCC-GB_00700111 COSM4890640 c.2324G>T p.G775V Substitution - Missense 16:2235541-2235541 + TCGA-BR-8487-01 COSM4059315 c.98T>C p.V33A Substitution - Missense 16:2223711-2223711 + CSCC-6-T COSM4479245 c.2307C>G p.V769V Substitution - coding silent 16:2235524-2235524 + TCGA-BR-8360-01 COSM4059319 c.737G>A p.R246H Substitution - Missense 16:2232762-2232762 + TCGA-ER-A19M-06 COSM3507700 c.1028C>T p.S343F Substitution - Missense 16:2233155-2233155 + I2L-P7-Tumor-Organoid COSM5363685 c.2208G>A p.V736V Substitution - coding silent 16:2235425-2235425 + TCGA-CM-6162-01 COSM1376708 c.1474C>T p.R492C Substitution - Missense 16:2234269-2234269 + B66 COSM1749485 c.1110G>A p.L370L Substitution - coding silent 16:2233491-2233491 + sysucc-880T COSM5462516 c.1124T>C p.M375T Substitution - Missense 16:2233505-2233505 + TCGA-AP-A0LM-01 COSM968664 c.1700G>A p.R567Q Substitution - Missense 16:2234689-2234689 + WA16 COSM237328 c.609+7C>T p.? Unknown 16:2232371-2232371 + I2L-P19Ta-Tumor-Organoid COSM5363330 c.1423G>A p.A475T Substitution - Missense 16:2234218-2234218 + TCGA-A2-A0T5-01 COSM3817540 c.465A>G p.G155G Substitution - coding silent 16:2232220-2232220 + WT033 COSM5352004 c.2129C>A p.T710N Substitution - Missense 16:2235346-2235346 + 18 COSM5745279 c.2122G>A p.A708T Substitution - Missense 16:2235339-2235339 + NCI-H716 COSM3279233 c.1089C>T p.S363S Substitution - coding silent 16:2233470-2233470 + ICGC_MB71 COSM3670189 c.23G>C p.R8P Substitution - Missense 16:2223636-2223636 + CRC-19T COSM5481288 c.2188G>A p.A730T Substitution - Missense 16:2235405-2235405 + TCGA-CM-4743-01 COSM1376706 c.1195G>A p.G399R Substitution - Missense 16:2233576-2233576 + YUKRIN COSM1708633 c.1462G>A p.E488K Substitution - Missense 16:2234257-2234257 + BD224T COSM5508638 c.2013C>A p.I671I Substitution - coding silent 16:2235230-2235230 + LIM1215 COSM4639407 c.1744C>A p.R582S Substitution - Missense 16:2234733-2234733 + LUAD-5V8LT COSM401609 c.1257G>C p.P419P Substitution - coding silent 16:2233638-2233638 + TCGA-FG-6692-01 COSM3969456 c.649C>T p.R217C Substitution - Missense 16:2232495-2232495 + Pat_11_A COSM5850477 c.937G>A p.E313K Substitution - Missense 16:2233064-2233064 + TCGA-BR-8081-01 COSM3507704 c.2067C>T p.I689I Substitution - coding silent 16:2235284-2235284 + PTC-10C COSM4128819 c.1158T>G p.A386A Substitution - coding silent 16:2233539-2233539 + TCGA-34-5232-01 COSM703017 c.256C>T p.P86S Substitution - Missense 16:2228470-2228470 + TCGA-UB-A7MB-01 COSM4932101 c.731-2A>C p.? Unknown 16:2232754-2232754 + TCGA-BK-A0CC-01 COSM968656 c.360C>G p.I120M Substitution - Missense 16:2229620-2229620 + MOLT-4 COSM1678775 c.1328C>T p.T443I Substitution - Missense 16:2233943-2233943 + OSCC-GB_00200111 COSM3711978 c.478G>T p.A160S Substitution - Missense 16:2232233-2232233 + TCGA-AU-6004-01 COSM1376722 c.2144delC p.E717fs*3 Deletion - Frameshift 16:2235361-2235361 + 7T COSM3711898 c.1038G>C p.M346I Substitution - Missense 16:2233165-2233165 + T3174 COSM3888199 c.1389C>T p.F463F Substitution - coding silent 16:2234184-2234184 + TCGA-22-5477-01 COSM703013 c.603C>G p.F201L Substitution - Missense 16:2232358-2232358 + TCGA-AD-6895-01 COSM1376721 c.2050G>A p.A684T Substitution - Missense 16:2235267-2235267 + PD6722a COSM5798063 c.1593+9C>G p.? Unknown 16:2234397-2234397 + T3535 COSM4679997 c.1469G>A p.R490H Substitution - Missense 16:2234264-2234264 + TCGA-AY-6197-01 COSM3279233 c.1089C>T p.S363S Substitution - coding silent 16:2233470-2233470 + ME024T COSM226316 c.1610A>G p.H537R Substitution - Missense 16:2234599-2234599 + B66-Tumor COSM1749485 c.1110G>A p.L370L Substitution - coding silent 16:2233491-2233491 + sysucc-880T COSM5462515 c.590G>A p.C197Y Substitution - Missense 16:2232345-2232345 + 3N62-VS-3T62 COSM4984431 c.631A>G p.M211V Substitution - Missense 16:2232477-2232477 + 2T COSM3711899 c.2193C>T p.I731I Substitution - coding silent 16:2235410-2235410 + TCGA-AA-3492-01 COSM1376705 c.1158_1159insG p.E388fs*55 Insertion - Frameshift 16:2233539-2233540 + T1760 COSM4679994 c.317C>T p.P106L Substitution - Missense 16:2229577-2229577 + T3610 COSM4679995 c.990C>T p.T330T Substitution - coding silent 16:2233117-2233117 + TCGA-CM-6674-01 COSM1376718 c.1796G>A p.G599D Substitution - Missense 16:2234862-2234862 + TCGA-AY-6197-01 COSM3690697 c.1742G>A p.G581D Substitution - Missense 16:2234731-2234731 + 134426 COSM320056 c.2272G>T p.D758Y Substitution - Missense 16:2235489-2235489 + C086 COSM5530294 c.1333C>T p.P445S Substitution - Missense 16:2233948-2233948 + 587338 COSM1204849 c.185G>A p.R62H Substitution - Missense 16:2228399-2228399 + B104-0 COSM1756915 c.1497C>G p.L499L Substitution - coding silent 16:2234292-2234292 + TCGA-DA-A1IA-06 COSM1708633 c.1462G>A p.E488K Substitution - Missense 16:2234257-2234257 + PD7205a COSM5772422 c.621C>T p.L207L Substitution - coding silent 16:2232467-2232467 + TCGA-BH-A18G-01 COSM3817543 c.1936-1G>A p.? Unknown 16:2235080-2235080 + PT46 COSM5929648 c.203C>T p.T68I Substitution - Missense 16:2228417-2228417 + YUKAE COSM5384518 c.1412C>T p.A471V Substitution - Missense 16:2234207-2234207 + TCGA-D1-A103-01 COSM968665 c.1986C>T p.G662G Substitution - coding silent 16:2235131-2235131 + KPOPBR-39-T COSM5964596 c.1851C>G p.A617A Substitution - coding silent 16:2234917-2234917 + I2L-P19Tb-Tumor-Organoid COSM5363498 c.348T>G p.T116T Substitution - coding silent 16:2229608-2229608 + TCGA-EE-A17X-06 COSM3507693 c.683C>T p.S228F Substitution - Missense 16:2232529-2232529 + HCA7 COSM4630181 c.1140C>T p.I380I Substitution - coding silent 16:2233521-2233521 + LS411 COSM4646514 c.650G>A p.R217H Substitution - Missense 16:2232496-2232496 + TCGA-CG-5726-01 COSM4059320 c.780G>A p.S260S Substitution - coding silent 16:2232805-2232805 + BRC11 COSM5028048 c.1286C>G p.S429* Substitution - Nonsense 16:2233901-2233901 + PD11339a COSM5776207 c.1687G>A p.V563M Substitution - Missense 16:2234676-2234676 + ME043T COSM228635 c.1841C>T p.P614L Substitution - Missense 16:2234907-2234907 + NB-1669 COSM1284679 c.1594-1G>A p.? Unknown 16:2234582-2234582 + TCGA-AP-A0LM-01 COSM968657 c.564G>T p.K188N Substitution - Missense 16:2232319-2232319 + TCGA-HU-A4GU-01 COSM1204851 c.400G>A p.A134T Substitution - Missense 16:2229660-2229660 + TCGA-G7-6793-01 COSM3988340 c.1721C>T p.P574L Substitution - Missense 16:2234710-2234710 + TCGA-BR-7703-01 COSM4059323 c.2242C>T p.Q748* Substitution - Nonsense 16:2235459-2235459 + 46M COSM5587696 c.1135G>T p.G379C Substitution - Missense 16:2233516-2233516 + 587342 COSM1204850 c.257C>A p.P86H Substitution - Missense 16:2228471-2228471 + TCGA-BG-A0MQ-01 COSM968666 c.2121C>T p.A707A Substitution - coding silent 16:2235338-2235338 + TCGA-BR-8361-01 COSM1204849 c.185G>A p.R62H Substitution - Missense 16:2228399-2228399 + TCGA-26-5139 COSM2157187 c.2118_2119delTG p.A707fs*40 Deletion - Frameshift 16:2235335-2235336 + TCGA-BR-4184-01 COSM4059321 c.1383G>A p.R461R Substitution - coding silent 16:2234178-2234178 + TCGA-AP-A059-01 COSM968663 c.1416C>T p.F472F Substitution - coding silent 16:2234211-2234211 + TCGA-D1-A103-01 COSM968659 c.812C>T p.T271I Substitution - Missense 16:2232837-2232837 + TCGA-DU-6400-01 COSM3969455 c.377C>T p.S126F Substitution - Missense 16:2229637-2229637 + BD49T COSM5498198 c.2037G>A p.V679V Substitution - coding silent 16:2235254-2235254 + MOLT-4 COSM1678774 c.1277G>T p.S426I Substitution - Missense 16:2233892-2233892 + PCSI_0083_Pa_P COSM3377830 c.878G>A p.R293H Substitution - Missense 16:2232903-2232903 + PT16_1 COSM5898521 c.814C>T p.P272S Substitution - Missense 16:2232839-2232839 + CHC1489T COSM3667790 c.568G>A p.G190S Substitution - Missense 16:2232323-2232323 + TCGA-51-4080-01 COSM703015 c.361G>C p.V121L Substitution - Missense 16:2229621-2229621 + TCGA-C5-A1BM-01 COSM4826528 c.1151G>C p.R384P Substitution - Missense 16:2233532-2233532 + ESCC_9 COSM5623611 c.1010T>G p.V337G Substitution - Missense 16:2233137-2233137 + sysucc-311T COSM5479059 c.571C>T p.R191C Substitution - Missense 16:2232326-2232326 + PCSI_0083_Pa_X COSM3787116 c.504G>A p.Q168Q Substitution - coding silent 16:2232259-2232259 + CHC892T COSM4958968 c.119G>A p.S40N Substitution - Missense 16:2223732-2223732 + C086 COSM5530295 c.496C>T p.P166S Substitution - Missense 16:2232251-2232251 + TCGA-B5-A11U-01 COSM968660 c.865_866delAA p.K289fs*79 Deletion - Frameshift 16:2232890-2232891 + TCGA-D1-A17H-01 COSM968667 c.2163G>T p.E721D Substitution - Missense 16:2235380-2235380 + ESCC_122 COSM5640653 c.1752C>T p.F584F Substitution - coding silent 16:2234741-2234741 + TCGA-13-1482-01 COSM74475 c.757T>G p.C253G Substitution - Missense 16:2232782-2232782 + 1N63-VS-1T63 COSM4977977 c.494G>A p.S165N Substitution - Missense 16:2232249-2232249 + TCGA-AZ-4615-01 COSM1204849 c.185G>A p.R62H Substitution - Missense 16:2228399-2228399 + TCGA-AA-3663-01 COSM1376703 c.1005C>T p.V335V Substitution - coding silent 16:2233132-2233132 + 20T COSM3711978 c.478G>T p.A160S Substitution - Missense 16:2232233-2232233 + TCGA-BH-A18G-01 COSM3817542 c.1274C>T p.A425V Substitution - Missense 16:2233889-2233889 + OSCC-GB_00070111 COSM3711898 c.1038G>C p.M346I Substitution - Missense 16:2233165-2233165 + CSB1 COSM5028047 c.261G>A p.P87P Substitution - coding silent 16:2228475-2228475 + CN-AML-CR-25-Dx COSM5426673 c.294G>A p.A98A Substitution - coding silent 16:2228508-2228508 + BD57T COSM5510771 c.1713C>T p.G571G Substitution - coding silent 16:2234702-2234702 + TCGA-E9-A3HO-01 COSM3817541 c.988A>G p.T330A Substitution - Missense 16:2233115-2233115 + CHEWS020 COSM4578825 c.2247C>T p.A749A Substitution - coding silent 16:2235464-2235464 + YUNACK COSM1708632 c.1072G>A p.E358K Substitution - Missense 16:2233453-2233453 + TCGA-FS-A1ZW-06 COSM3507705 c.2350G>A p.V784I Substitution - Missense 16:2235567-2235567 + TCGA-A6-5661-01 COSM1376719 c.1866G>A p.T622T Substitution - coding silent 16:2234932-2234932 + TCGA-ER-A193-06 COSM3888199 c.1389C>T p.F463F Substitution - coding silent 16:2234184-2234184 + TCGA-D9-A1JW-06 COSM3507702 c.1384C>T p.P462S Substitution - Missense 16:2234179-2234179 + TCGA-EE-A20C-06 COSM3507704 c.2067C>T p.I689I Substitution - coding silent 16:2235284-2235284 + CCK81 COSM4620698 c.1874C>T p.P625L Substitution - Missense 16:2234940-2234940 + HCC152T COSM3706941 c.129C>T p.L43L Substitution - coding silent 16:2223742-2223742 + T578 COSM4679996 c.1008C>T p.H336H Substitution - coding silent 16:2233135-2233135 + TCGA-AD-6895-01 COSM1204851 c.400G>A p.A134T Substitution - Missense 16:2229660-2229660 + TCGA-A6-6781-01 COSM1376701 c.519C>T p.L173L Substitution - coding silent 16:2232274-2232274 + 49M COSM5590711 c.941C>T p.P314L Substitution - Missense 16:2233068-2233068 + CSCC-38-T COSM4555605 c.661G>A p.E221K Substitution - Missense 16:2232507-2232507 + HCC152 COSM3706941 c.129C>T p.L43L Substitution - coding silent 16:2223742-2223742 + Gp5D COSM3279231 c.1039A>G p.K347E Substitution - Missense 16:2233166-2233166 + ESCC_157 COSM5646264 c.887C>G p.S296C Substitution - Missense 16:2233014-2233014 + DN110E9 COSM5772422 c.621C>T p.L207L Substitution - coding silent 16:2232467-2232467 + OSCC-GB_00020111 COSM3711899 c.2193C>T p.I731I Substitution - coding silent 16:2235410-2235410 + TCGA-BR-6563-01 COSM1376708 c.1474C>T p.R492C Substitution - Missense 16:2234269-2234269 + ORL-48 COSM4596740 c.877C>T p.R293C Substitution - Missense 16:2232902-2232902 + pfg181T COSM4748654 c.1024C>A p.L342M Substitution - Missense 16:2233151-2233151 + TCGA-B5-A11E-01 COSM968661 c.884-1G>T p.? Unknown 16:2233010-2233010 + TCGA-E2-A1L7-01 COSM1478660 c.1541C>T p.S514L Substitution - Missense 16:2234336-2234336 + CSCC-44-T COSM4445849 c.158-3C>T p.? Unknown 16:2228369-2228369 + 587234 COSM1204851 c.400G>A p.A134T Substitution - Missense 16:2229660-2229660 + B62-0 COSM1749486 c.1952C>T p.A651V Substitution - Missense 16:2235097-2235097 + TCGA-BS-A0UA-01 COSM968662 c.902C>T p.A301V Substitution - Missense 16:2233029-2233029 +

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.513268 16p13.3 603022 Hs.615134;Hs.615137;Hs.615139;Hs.615142;Hs.615144;Hs.615147;Hs.615151;Hs.615152;Hs.615156;Hs.615157;Hs.615161;Hs.615175;Hs.615176;Hs.615178;Hs.615179;Hs.615180;Hs.615184;Hs.615188;Hs.615191;Hs.615196;Hs.615200;Hs.615209;Hs.615210;Hs.615213;Hs.615215;Hs.615220;Hs.615221;Hs.615224;Hs.615225;Hs.615230;Hs.615232;Hs.615233;Hs.615234;Hs.615235;Hs.615236;Hs.615238;Hs.615242;Hs.615243;Hs.615244;Hs.615245;Hs.615246;Hs.615247;Hs.615249;Hs.615250;Hs.615251;Hs.615252;Hs.615253;Hs.615254;Hs.615255;Hs.615256;Hs.615257;Hs.615261;Hs.615263;Hs.615265;Hs.615266;Hs.615267;Hs.615272;Hs.615273;Hs.615275;Hs.615276;Hs.615277;Hs.615278;Hs.615279;Hs.615283 16p13.3 603022

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer AA - Frameshift p.K289Rfs*79 c.866_867delAA 16 2282891 UCEC C A Synonymous p.T663T c.1989C>A 16 2285135 STAD - C Frameshift p.V355Rfs*14 c.1062dupC 16 2283439 NB C G Missense p.F201L c.603C>G 16 2282359 LUSC C G Nonsense p.S429* c.1286C>G 16 2283902 BRCA C G Synonymous p.L173L c.519C>G 16 2282275 LUSC C T IntronicSNV . c.1056+20C>T 16 2283204 CM C T IntronicSNV . c.1056+40C>T 16 2283224 CM C T Missense p.A301V c.902C>T 16 2283030 UCEC C T Missense p.H670Y c.2008C>T 16 2285226 STAD C T Missense p.P462S c.1384C>T 16 2284180 CM C T Missense p.P86S c.256C>T 16 2278471 LUSC C T Missense p.R217C c.649C>T 16 2282496 LGG C T Missense p.S126F c.377C>T 16 2279638 LGG C T Missense p.S228F c.683C>T 16 2282530 CM C T Missense p.S514L c.1541C>T 16 2284337 BRCA C T Missense p.T712I c.2135C>T 16 2285353 CM C T Synonymous p.A707A c.2121C>T 16 2285339 UCEC C T Synonymous p.I689I c.2067C>T 16 2285285 CM C T Synonymous p.P354P c.1062C>T 16 2283444 BRCA G A Missense p.E161K c.481G>A 16 2282237 HNSC G A Missense p.E488K c.1462G>A 16 2284258 CM G A Missense p.E760K c.2278G>A 16 2285496 LUAD G A Missense p.G497R c.1489G>A 16 2284285 STAD G A Missense p.R384H c.1151G>A 16 2283533 THCA G A Missense p.V784I c.2350G>A 16 2285568 CM G A SpliceAcceptorSNV . c.1594-1G>A 16 2284583 NB G A Synonymous p.A25A c.75G>A 16 2273689 HNSC G A Synonymous p.A31A c.93G>A 16 2273707 HNSC G A Synonymous p.E352E c.1056G>A 16 2283184 CM G A Synonymous p.P87P c.261G>A 16 2278476 BRCA G A Synonymous p.R8R c.24G>A 16 2273638 BRCA G A Synonymous p.S260S c.780G>A 16 2282806 STAD G A Synonymous p.T243T c.729G>A 16 2282576 STAD G C Missense p.A464P c.1390G>C 16 2284186 CM G C Missense p.V121L c.361G>C 16 2279622 LUSC G T Missense p.C82F c.245G>T 16 2278460 LUAD G T Missense p.D758Y c.2272G>T 16 2285490 SCLC G T Missense p.R84L c.251G>T 16 2278466 LUAD G T Nonsense p.E352* c.1054G>T 16 2283182 HNSC T G Missense p.C253G c.757T>G 16 2282783 OV